CYP2A6 c.1454G>T ;(p.R485L)

Variant ID: 19-41349732-C-A

NM_000762.5(CYP2A6):c.1454G>T;(p.R485L)

This variant was identified in 38 publications

View GRCh38 version.




Publications:


Integrative proteogenomic characterization of early esophageal cancer.

Nature Communications
Li, Lingling L; Jiang, Dongxian D; Zhang, Qiao Q; Liu, Hui H; Xu, Fujiang F; Guo, Chunmei C; Qin, Zhaoyu Z; Wang, Haixing H; Feng, Jinwen J; Liu, Yang Y; Chen, Weijie W; Zhang, Xue X; Bai, Lin L; Tian, Sha S; Tan, Subei S; Xu, Chen C; Song, Qi Q; Liu, Yalan Y; Zhong, Yunshi Y; Chen, Tianyin T; Zhou, Pinghong P; Zhao, Jian-Yuan JY; Hou, Yingyong Y; Ding, Chen C
Publication Date: 2023-03-25

Variant appearance in text: CYP2A6: R485L; rs28399468
PubMed Link: 36966136
Variant Present in the following documents:
  • 41467_2023_37440_MOESM4_ESM.xlsx, sheet 2
View BVdb publication page



Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.

Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Publication Date: 2022-10-14

Variant appearance in text: CYP2A6: R485L
PubMed Link: 36241656
Variant Present in the following documents:
  • 41598_2022_20939_MOESM6_ESM.xlsx, sheet 2
View BVdb publication page



The metabolic genomic atlas reveals potential drivers and clinically relevant insights into the etiology of esophageal squamous cell carcinoma.

Theranostics
Liu, Xuesong X; Hong, Ruoxi R; Du, Peina P; Yang, Di D; He, Meibo M; Wu, Qingnan Q; Li, Lin L; Wang, Yan Y; Chen, Jie J; Min, Qingjie Q; Li, Jinting J; Zhang, Weimin W; Zhan, Qimin Q
Publication Date: 2022

Variant appearance in text: CYP2A6: 1454G>T; R485L
PubMed Link: 36168622
Variant Present in the following documents:
  • thnov12p6160s2.xlsx, sheet 2
View BVdb publication page



The genetic landscape of major drug metabolizing cytochrome P450 genes-an updated analysis of population-scale sequencing data.

The Pharmacogenomics Journal
Zhou, Yitian Y; Lauschke, Volker M VM
Publication Date: 2022-12

Variant appearance in text: CYP2A6: R485L; rs28399468
PubMed Link: 36068297
Variant Present in the following documents:
  • Main text
  • 41397_2022_Article_288.pdf
View BVdb publication page



Deciphering Structural Alterations Associated with Activity Reductions of Genetic Polymorphisms in Cytochrome P450 2A6 Using Molecular Dynamics Simulations.

International Journal Of Molecular Sciences
Kato, Koichi K; Nakayoshi, Tomoki T; Nokura, Rika R; Hosono, Hiroki H; Hiratsuka, Masahiro M; Ishikawa, Yoshinobu Y; Kurimoto, Eiji E; Oda, Akifumi A
Publication Date: 2021-09-19

Variant appearance in text: CYP2A6: R485L
PubMed Link: 34576282
Variant Present in the following documents:
  • Main text
  • ijms-22-10119.pdf
View BVdb publication page



Functional characterization of novel rare CYP2A6 variants and potential implications for clinical outcomes.

Clinical And Translational Science
El-Boraie, Ahmed A; Tanner, Julie-Anne JA; Zhu, Andy Z X AZX; Claw, Katrina G KG; Prasad, Bhagwat B; Schuetz, Erin G EG; Thummel, Kenneth E KE; Fukunaga, Koya K; Mushiroda, Taisei T; Kubo, Michiaki M; Benowitz, Neal L NL; Lerman, Caryn C; Tyndale, Rachel F RF
Publication Date: 2021-09-03

Variant appearance in text: CYP2A6: 1454G>T; R485L; rs28399468
PubMed Link: 34476898
Variant Present in the following documents:
  • CTS-15-204-s001.pdf
  • CTS-15-204.pdf
View BVdb publication page



Functional characterization of novel rare CYP2A6 variants and potential implications for clinical outcomes.

Clinical And Translational Science
El-Boraie, Ahmed A; Tanner, Julie-Anne JA; Zhu, Andy Z X AZX; Claw, Katrina G KG; Prasad, Bhagwat B; Schuetz, Erin G EG; Thummel, Kenneth E KE; Fukunaga, Koya K; Mushiroda, Taisei T; Kubo, Michiaki M; Benowitz, Neal L NL; Lerman, Caryn C; Tyndale, Rachel F RF
Publication Date: 2022-01

Variant appearance in text: CYP2A6: 1454G>T; R485L; rs28399468
PubMed Link: 34476898
Variant Present in the following documents:
  • CTS-15-204-s001.pdf
  • CTS-15-204.pdf
View BVdb publication page



Genetic Variants in Smoking-Related Genes in Two Smoking Cessation Programs: A Cross-Sectional Study.

International Journal Of Environmental Research And Public Health
Pérez-Rubio, Gloria G; López-Flores, Luis Alberto LA; Cupertino, Ana Paula AP; Cartujano-Barrera, Francisco F; Reynales-Shigematsu, Luz Myriam LM; Ramírez, Mariana M; Ellerbeck, Edward F EF; Rodríguez-Bolaños, Rosibel R; Falfan-Valencia, Ramcés R
Publication Date: 2021-06-19

Variant appearance in text: rs28399468
PubMed Link: 34205269
Variant Present in the following documents:
  • Main text
  • ijerph-18-06597.pdf
View BVdb publication page



Biochemistry of nicotine metabolism and its relevance to lung cancer.

The Journal Of Biological Chemistry
Murphy, Sharon E SE
Publication Date: 2021

Variant appearance in text: rs28399468
PubMed Link: 33932402
Variant Present in the following documents:
  • Main text
View BVdb publication page



Actionable pharmacogenetic variants in Hong Kong Chinese exome sequencing data and projected prescription impact in the Hong Kong population.

Plos Genetics
Yu, Mullin Ho Chung MHC; Chan, Marcus Chun Yin MCY; Chung, Claudia Ching Yan CCY; Li, Andrew Wang Tat AWT; Yip, Chara Yin Wa CYW; Mak, Christopher Chun Yu CCY; Chau, Jeffrey Fong Ting JFT; Lee, Mianne M; Fung, Jasmine Lee Fong JLF; Tsang, Mandy Ho Yin MHY; Chan, Joshua Chun Ki JCK; Wong, Wilfred Hing Sang WHS; Yang, Jing J; Chui, William Chun Ming WCM; Chung, Patrick Ho Yu PHY; Yang, Wanling W; Lee, So Lun SL; Chan, Godfrey Chi Fung GCF; Tam, Paul Kwong Hang PKH; Lau, Yu Lung YL; Tang, Clara Sze Man CSM; Yeung, Kit San KS; Chung, Brian Hon Yin BHY
Publication Date: 2021-02

Variant appearance in text: rs28399468
PubMed Link: 33600428
Variant Present in the following documents:
  • pgen.1009323.s010.xlsx, sheet 1
View BVdb publication page



Population Pharmacokinetic and Pharmacogenetic Analysis of Mitotane in Patients with Adrenocortical Carcinoma: Towards Individualized Dosing.

Clinical Pharmacokinetics
Yin, Anyue A; Ettaieb, Madeleine H T MHT; Swen, Jesse J JJ; van Deun, Liselotte L; Kerkhofs, Thomas M A TMA; van der Straaten, Robert J H M RJHM; Corssmit, Eleonora P M EPM; Gelderblom, Hans H; Kerstens, Michiel N MN; Feelders, Richard A RA; Eekhoff, Marelise M; Timmers, Henri J L M HJLM; D'Avolio, Antonio A; Cusato, Jessica J; Guchelaar, Henk-Jan HJ; Haak, Harm R HR; Moes, Dirk Jan A R DJAR
Publication Date: 2021-01

Variant appearance in text: CYP2A6: R485L; rs28399468
PubMed Link: 32607875
Variant Present in the following documents:
  • 40262_2020_913_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Identification of a nonsense mutation in TNNI3K associated with cardiac conduction disease.

Journal Of Clinical Laboratory Analysis
Liu, Jiang J; Liu, Da D; Li, Muzheng M; Wu, Keke K; Liu, Na N; Zhao, Chenyu C; Shi, Xiaoliu X; Liu, Qiming Q
Publication Date: 2020-09

Variant appearance in text: CYP2A6: R485L; rs28399468
PubMed Link: 32529721
Variant Present in the following documents:
  • JCLA-34-e23418-s003.xls, sheet 1
View BVdb publication page



Genetic polymorphisms of the drug-metabolizing enzyme cytochrome P450 2A6 in a Tibetan Chinese population.

International Journal Of Clinical And Experimental Pathology
Xia, Ridong R; Zhu, Xikai X; Chen, Zhengshuai Z; He, Yongjun Y; Kang, Longli L; Yuan, Dongya D; Jin, Tianbo T; Wang, Li L
Publication Date: 2018

Variant appearance in text: CYP2A6: Arg485Leu; rs28399468
PubMed Link: 31949579
Variant Present in the following documents:
  • Main text
View BVdb publication page



Whole-genome landscape of mucosal melanoma reveals diverse drivers and therapeutic targets.

Nature Communications
Newell, Felicity F; Kong, Yan Y; Wilmott, James S JS; Johansson, Peter A PA; Ferguson, Peter M PM; Cui, Chuanliang C; Li, Zhongwu Z; Kazakoff, Stephen H SH; Burke, Hazel H; Dodds, Tristan J TJ; Patch, Ann-Marie AM; Nones, Katia K; Tembe, Varsha V; Shang, Ping P; van der Weyden, Louise L; Wong, Kim K; Holmes, Oliver O; Lo, Serigne S; Leonard, Conrad C; Wood, Scott S; Xu, Qinying Q; Rawson, Robert V RV; Mukhopadhyay, Pamela P; Dummer, Reinhard R; Levesque, Mitchell P MP; Jönsson, Göran G; Wang, Xuan X; Yeh, Iwei I; Wu, Hong H; Joseph, Nancy N; Bastian, Boris C BC; Long, Georgina V GV; Spillane, Andrew J AJ; Shannon, Kerwin F KF; Thompson, John F JF; Saw, Robyn P M RPM; Adams, David J DJ; Si, Lu L; Pearson, John V JV; Hayward, Nicholas K NK; Waddell, Nicola N; Mann, Graham J GJ; Guo, Jun J; Scolyer, Richard A RA
Publication Date: 2019-07-18

Variant appearance in text: CYP2A6: 1454G>T; Arg485Leu
PubMed Link: 31320640
Variant Present in the following documents:
  • 41467_2019_11107_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Evolving neoantigen profiles in colorectal cancers with DNA repair defects.

Genome Medicine
Rospo, Giuseppe G; Lorenzato, Annalisa A; Amirouchene-Angelozzi, Nabil N; Magrì, Alessandro A; Cancelliere, Carlotta C; Corti, Giorgio G; Negrino, Carola C; Amodio, Vito V; Montone, Monica M; Bartolini, Alice A; Barault, Ludovic L; Novara, Luca L; Isella, Claudio C; Medico, Enzo E; Bertotti, Andrea A; Trusolino, Livio L; Germano, Giovanni G; Di Nicolantonio, Federica F; Bardelli, Alberto A
Publication Date: 2019-06-28

Variant appearance in text: CYP2A6: R485L
PubMed Link: 31253177
Variant Present in the following documents:
  • 13073_2019_654_MOESM2_ESM.xlsx, sheet 57
View BVdb publication page



Genetic Evidence Supporting the Role of the Calcium Channel, CACNA1S, in Tooth Cusp and Root Patterning.

Frontiers In Physiology
Laugel-Haushalter, Virginie V; Morkmued, Supawich S; Stoetzel, Corinne C; Geoffroy, Véronique V; Muller, Jean J; Boland, Anne A; Deleuze, Jean-François JF; Chennen, Kirsley K; Pitiphat, Waranuch W; Dollfus, Hélène H; Niederreither, Karen K; Bloch-Zupan, Agnès A; Pungchanchaikul, Patimaporn P
Publication Date: 2018

Variant appearance in text: CYP2A6: 1454G>T; Arg485Leu; rs28399468
PubMed Link: 30319441
Variant Present in the following documents:
  • Table_5.xlsx, sheet 1
View BVdb publication page



An optimized prediction framework to assess the functional impact of pharmacogenetic variants.

The Pharmacogenomics Journal
Zhou, Yitian Y; Mkrtchian, Souren S; Kumondai, Masaki M; Hiratsuka, Masahiro M; Lauschke, Volker M VM
Publication Date: 2019-04

Variant appearance in text: CYP2A6: R485L; rs28399468
PubMed Link: 30206299
Variant Present in the following documents:
  • 41397_2018_44_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



P450 Pharmacogenetics in Indigenous North American Populations.

Journal Of Personalized Medicine
Henderson, Lindsay M LM; Claw, Katrina G KG; Woodahl, Erica L EL; Robinson, Renee F RF; Boyer, Bert B BB; Burke, Wylie W; Thummel, Kenneth E KE
Publication Date: 2018-02-01

Variant appearance in text: rs28399468
PubMed Link: 29389890
Variant Present in the following documents:
  • Main text
  • jpm-08-00009.pdf
View BVdb publication page



Variation in CYP2A6 Activity and Personalized Medicine.

Journal Of Personalized Medicine
Tanner, Julie-Anne JA; Tyndale, Rachel F RF
Publication Date: 2017-12-01

Variant appearance in text: CYP2A6: R485L; rs28399468
PubMed Link: 29194389
Variant Present in the following documents:
  • Main text
  • jpm-07-00018.pdf
View BVdb publication page



Comprehensive genomic analysis of Oesophageal Squamous Cell Carcinoma reveals clinical relevance.

Scientific Reports
Du, Peina P; Huang, Peide P; Huang, Xuanlin X; Li, Xiangchun X; Feng, Zhimin Z; Li, Fengyu F; Liang, Shaoguang S; Song, Yongmei Y; Stenvang, Jan J; Brünner, Nils N; Yang, Huanming H; Ou, Yunwei Y; Gao, Qiang Q; Li, Lin L
Publication Date: 2017-11-10

Variant appearance in text: CYP2A6: 1454G>T
PubMed Link: 29127303
Variant Present in the following documents:
  • 41598_2017_14909_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



CYP2A6 Polymorphisms Associate with Outcomes of S-1 Plus Oxaliplatin Chemotherapy in Chinese Gastric Cancer Patients.

Genomics, Proteomics & Bioinformatics
Yang, Lin L; Zou, Shanshan S; Shu, Chang C; Song, Yan Y; Sun, Yong-Kun YK; Zhang, Wen W; Zhou, Aiping A; Yuan, Xinghua X; Yang, Yi Y; Hu, Songnian S
Publication Date: 2017-08

Variant appearance in text: rs28399468
PubMed Link: 28811232
Variant Present in the following documents:
  • Main text
View BVdb publication page



Distribution of polymorphic variants of CYP2A6 and their involvement in nicotine addiction.

Excli Journal
López-Flores, Luis A LA; Pérez-Rubio, Gloria G; Falfán-Valencia, Ramcés R
Publication Date: 2017

Variant appearance in text: CYP2A6: Arg485Leu
PubMed Link: 28507465
Variant Present in the following documents:
  • Main text
  • EXCLI-16-174.pdf
View BVdb publication page



Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.

Clinical Pharmacology And Therapeutics
Zhou, Y Y; Ingelman-Sundberg, M M; Lauschke, V M VM
Publication Date: 2017-10

Variant appearance in text: CYP2A6: R485L; rs28399468
PubMed Link: 28378927
Variant Present in the following documents:
  • Main text
View BVdb publication page



A phase II study of preoperative chemoradiation with tegafur-uracil plus leucovorin for locally advanced rectal cancer with pharmacogenetic analysis.

Radiation Oncology (London, England)
Kim, Sun Young SY; Baek, Ji Yeon JY; Oh, Jae Hwan JH; Park, Sung Chan SC; Sohn, Dae Kyung DK; Kim, Min Ju MJ; Chang, Hee Jin HJ; Kong, Sun-Young SY; Kim, Dae Yong DY
Publication Date: 2017-03-27

Variant appearance in text: rs28399468
PubMed Link: 28347333
Variant Present in the following documents:
  • Main text
  • 13014_2017_Article_800.pdf
View BVdb publication page



Characterization of ADME gene variation in 21 populations by exome sequencing.

Pharmacogenetics And Genomics
Hovelson, Daniel H DH; Xue, Zhengyu Z; Zawistowski, Matthew M; Ehm, Margaret G MG; Harris, Elizabeth C EC; Stocker, Sophie L SL; Gross, Annette S AS; Jang, In-Jin IJ; Ieiri, Ichiro I; Lee, Jong-Eun JE; Cardon, Lon R LR; Chissoe, Stephanie L SL; Abecasis, Gonçalo G; Nelson, Matthew R MR
Publication Date: 2017-03

Variant appearance in text: rs28399468
PubMed Link: 27984508
Variant Present in the following documents:
  • fpc-27-089-s005.xlsx, sheet 2
  • fpc-27-089-s004.xlsx, sheet 2
View BVdb publication page



Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk.

Cancer Research
Patel, Yesha M YM; Park, Sunghim L SL; Han, Younghun Y; Wilkens, Lynne R LR; Bickeböller, Heike H; Rosenberger, Albert A; Caporaso, Neil N; Landi, Maria Teresa MT; Brüske, Irene I; Risch, Angela A; Wei, Yongyue Y; Christiani, David C DC; Brennan, Paul P; Houlston, Richard R; McKay, James J; McLaughlin, John J; Hung, Rayjean R; Murphy, Sharon S; Stram, Daniel O DO; Amos, Christopher C; Le Marchand, Loïc L
Publication Date: 2016-10-01

Variant appearance in text: rs28399468
PubMed Link: 27488534
Variant Present in the following documents:
  • Main text
View BVdb publication page



CYP2A6 genotyping methods and strategies using real-time and end point PCR platforms.

Pharmacogenomics
Wassenaar, Catherine A CA; Zhou, Qian Q; Tyndale, Rachel F RF
Publication Date: 2016

Variant appearance in text: rs28399468
PubMed Link: 26670214
Variant Present in the following documents:
  • Main text
View BVdb publication page



Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Plos One
Holehouse, Alex S AS; Naegle, Kristen M KM
Publication Date: 2015

Variant appearance in text: rs28399468
PubMed Link: 26659599
Variant Present in the following documents:
  • pone.0144692.s002.xlsx, sheet 1
View BVdb publication page



Characterization of 137 Genomic DNA Reference Materials for 28 Pharmacogenetic Genes: A GeT-RM Collaborative Project.

The Journal Of Molecular Diagnostics : Jmd
Pratt, Victoria M VM; Everts, Robin E RE; Aggarwal, Praful P; Beyer, Brittany N BN; Broeckel, Ulrich U; Epstein-Baak, Ruth R; Hujsak, Paul P; Kornreich, Ruth R; Liao, Jun J; Lorier, Rachel R; Scott, Stuart A SA; Smith, Chingying Huang CH; Toji, Lorraine H LH; Turner, Amy A; Kalman, Lisa V LV
Publication Date: 2016-01

Variant appearance in text: CYP2A6: R485L
PubMed Link: 26621101
Variant Present in the following documents:
  • Main text
View BVdb publication page



The Affymetrix DMET Plus platform reveals unique distribution of ADME-related variants in ethnic Arabs.

Disease Markers
Wakil, Salma M SM; Nguyen, Cao C; Muiya, Nzioka P NP; Andres, Editha E; Lykowska-Tarnowska, Agnieszka A; Baz, Batoul B; Tahir, Asma I AI; Meyer, Brian F BF; Morahan, Grant G; Dzimiri, Nduna N
Publication Date: 2015

Variant appearance in text: rs28399468
PubMed Link: 25802476
Variant Present in the following documents:
  • 542543.f1.xlsx, sheet 1
View BVdb publication page



The RPTEC/TERT1 cell line models key renal cell responses to the environmental toxicants, benzo[a]pyrene and cadmium.

Toxicology Reports
Simon, B R BR; Wilson, M J MJ; Wickliffe, J K JK
Publication Date: 2014

Variant appearance in text: rs28399468
PubMed Link: 25126521
Variant Present in the following documents:
  • mmc1.xls, sheet 1
View BVdb publication page



Screening for 392 polymorphisms in 141 pharmacogenes.

Biomedical Reports
Kim, Jason Yongha JY; Cheong, Hyun Sub HS; Park, Tae-Joon TJ; Shin, Hee Jung HJ; Seo, Doo Won DW; Na, Han Sung HS; Chung, Myeon Woo MW; Shin, Hyoung Doo HD
Publication Date: 2014-07

Variant appearance in text: rs28399468
PubMed Link: 24944790
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic polymorphisms of metabolic enzymes and the pharmacokinetics of indapamide in Taiwanese subjects.

The Aaps Journal
Wang, Teng-Hsu TH; Hsiong, Cheng-Huei CH; Ho, Hsin-Tien HT; Shih, Tung-Yuan TY; Yen, San-Jan SJ; Wang, Hui-Hung HH; Wu, Jer-Yuarn JY; Kuo, Benjamin Pei-Chung BP; Chen, Yuan-Tsong YT; Ho, Shung-Tai ST; Hu, Oliver Yoa-Pu OY
Publication Date: 2014-03

Variant appearance in text: CYP2A6: R485L; rs28399468
PubMed Link: 24357089
Variant Present in the following documents:
  • Main text
View BVdb publication page



Cytochrome p450 metabolism of betel quid-derived compounds: implications for the development of prevention strategies for oral and pharyngeal cancers.

Thescientificworldjournal
Lin, Che-Yi CY; Pan, Tien-Szu TS; Ting, Chun-Chan CC; Liang, Shih-Shin SS; Huang, Shu-Hung SH; Liu, Hsiu-Yueh HY; Ko, Edward Cheng-Chuan EC; Wu, Chung-Wei CW; Tang, Jen-Yang JY; Chen, Ping-Ho PH
Publication Date: 2013

Variant appearance in text: CYP2A6: R485L
PubMed Link: 23983642
Variant Present in the following documents:
  • Main text
  • TSWJ2013-618032.pdf
View BVdb publication page



Bioinformatics and variability in drug response: a protein structural perspective.

Journal Of The Royal Society, Interface
Lahti, Jennifer L JL; Tang, Grace W GW; Capriotti, Emidio E; Liu, Tianyun T; Altman, Russ B RB
Publication Date: 2012-07-07

Variant appearance in text: rs28399468
PubMed Link: 22552919
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mechanism-based inhibition of cytochrome P450 (CYP)2A6 by chalepensin in recombinant systems, in human liver microsomes and in mice in vivo.

British Journal Of Pharmacology
Ueng, Yune-Fang YF; Chen, Chien-Chih CC; Chung, Yu-Ting YT; Liu, Tsung-Yun TY; Chang, Yu-Ping YP; Lo, Wei-Sheng WS; Murayama, Norie N; Yamazaki, Hiroshi H; Souček, Pavel P; Chau, Gar-Yang GY; Chi, Chin-Wen CW; Chen, Ruei-Ming RM; Li, Ding-Tzai DT
Publication Date: 2011-07

Variant appearance in text: CYP2A6: Arg485Leu
PubMed Link: 21418183
Variant Present in the following documents:
  • Main text
View BVdb publication page



A novel CYP2A6 allele (CYP2A6*35) resulting in an amino-acid substitution (Asn438Tyr) is associated with lower CYP2A6 activity in vivo.

The Pharmacogenomics Journal
Al Koudsi, Nael N; Ahluwalia, Jasjit S JS; Lin, Shih-Ku SK; Sellers, Edward M EM; Tyndale, Rachel F RF
Publication Date: 2009-08

Variant appearance in text: CYP2A6: R485L
PubMed Link: 19365400
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genotyping panel for assessing response to cancer chemotherapy.

Bmc Medical Genomics
Dai, Zunyan Z; Papp, Audrey C AC; Wang, Danxin D; Hampel, Heather H; Sadee, Wolfgang W
Publication Date: 2008-06-11

Variant appearance in text: rs28399468
PubMed Link: 18547414
Variant Present in the following documents:
  • 1755-8794-1-24-S1.xls, sheet 1
View BVdb publication page



Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolism.

British Journal Of Clinical Pharmacology
Yoshida, Ryoko R; Nakajima, Miki M; Watanabe, Yuki Y; Kwon, Jun-Tack JT; Yokoi, Tsuyoshi T
Publication Date: 2002-11

Variant appearance in text: CYP2A6: R485L
PubMed Link: 12445030
Variant Present in the following documents:
  • Main text
View BVdb publication page