Genetic variations in relation to bleeding and pharmacodynamics of dabigatran in Chinese patients with nonvalvular atrial fibrillation: A nationwide multicentre prospective cohort study.
Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing.
Frontiers In Pharmacology
Silgado-Guzmán, Daniel Felipe DF; Angulo-Aguado, Mariana M; Morel, Adrien A; Niño-Orrego, María José MJ; Ruiz-Torres, Daniel-Armando DA; Contreras Bravo, Nora Constanza NC; Restrepo, Carlos Martin CM; Ortega-Recalde, Oscar O; Fonseca-Mendoza, Dora Janeth DJ
Validation of Genetic Markers Associated with Survival in Colorectal Cancer Patients Treated with Oxaliplatin-Based Chemotherapy.
Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Park, Hanla A HA; Seibold, Petra P; Edelmann, Dominic D; Benner, Axel A; Canzian, Federico F; Alwers, Elizabeth E; Jansen, Lina L; Schneider, Martin M; Hoffmeister, Michael M; Brenner, Hermann H; Chang-Claude, Jenny J
Polymorphisms in the CYP2A6 and ABCC4 genes are associated with a protective effect on chronic myeloid leukemia in the Brazilian Amazon population.
Molecular Genetics & Genomic Medicine
Monte, Natasha N; Pantoja, Karla B C C KBCC; Rodrigues, Juliana C G JCG; de Carvalho, Darlen C DC; Azevedo, Tereza C B TCB; Pereira, Esdras E B EEB; de Assumpção, Paulo P PP; Dos Santos, Sidney E B SEB; Fernandes, Marianne R MR; Dos Santos, Ney P C NPC
Polymorphisms in the CYP2A6 and ABCC4 genes are associated with a protective effect on chronic myeloid leukemia in the Brazilian Amazon population.
Molecular Genetics & Genomic Medicine
Monte, Natasha N; Pantoja, Karla B C C KBCC; Rodrigues, Juliana C G JCG; de Carvalho, Darlen C DC; Azevedo, Tereza C B TCB; Pereira, Esdras E B EEB; de Assumpção, Paulo P PP; Dos Santos, Sidney E B SEB; Fernandes, Marianne R MR; Dos Santos, Ney P C NPC
Polymorphisms of xenobiotic-metabolizing and transporter genes, and the risk of gastric and colorectal cancer in an admixed population from the Brazilian Amazon.
American Journal Of Translational Research
de Castro, Amanda Nazaré Cohen Lima ANCL; Fernandes, Marianne Rodrigues MR; de Carvalho, Darlen Cardoso DC; de Souza, Tatiane Piedade TP; Rodrigues, Juliana Carla Gomes JCG; Andrade, Roberta Borges RB; Modesto, Antonio Andre Conde AAC; Santos, Sidney S; Assumpção, Paulo Pimentel PP; Dos Santos, Ney Pereira Carneiro NPC
A pharmacokinetic and pharmacogenetic evaluation of contraceptive implants and antiretroviral therapy among women in Kenya and Uganda.
Aids (London, England)
Patel, Rena C RC; Stalter, Randy M RM; Thomas, Katherine K KK; Tamraz, Bani B; Blue, Steven W SW; Erikson, David W DW; Kim, Christina J CJ; Kelly, Edward J EJ; Nanda, Kavita K; Kourtis, Athena P AP; Lingappa, Jairam R JR; Mugo, Nelly N; Baeten, Jared M JM; Scarsi, Kimberly K KK; ,
Polymorphisms in cytochrome P450 are associated with extensive efavirenz pharmacokinetics and CNS toxicities in an HIV cohort in Botswana.
The Pharmacogenomics Journal
Vujkovic, Marijana M; Bellamy, Scarlett L SL; Zuppa, Athena F AF; Gastonguay, Marc R MR; Moorthy, Ganesh S GS; Ratshaa, Bakgaki B; Han, Xiaoyan X; Steenhoff, Andrew P AP; Mosepele, Mosepele M; Strom, Brian L BL; Bisson, Gregory P GP; Aplenc, Richard R; Gross, Robert R
Comprehensive Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Evaluation of Once-Daily Efavirenz 400 and 600 mg in Treatment-Naïve HIV-Infected Patients at 96 Weeks: Results of the ENCORE1 Study.
Clinical Pharmacokinetics
Dickinson, Laura L; Amin, Janaki J; Else, Laura L; Boffito, Marta M; Egan, Deirdre D; Owen, Andrew A; Khoo, Saye S; Back, David D; Orrell, Catherine C; Clarke, Amanda A; Losso, Marcelo M; Phanuphak, Praphan P; Carey, Dianne D; Cooper, David A DA; Emery, Sean S; Puls, Rebekah R
Pharmacokinetic and Pharmacodynamic Comparison of Once-Daily Efavirenz (400 mg vs. 600 mg) in Treatment-Naïve HIV-Infected Patients: Results of the ENCORE1 Study.
Clinical Pharmacology And Therapeutics
Dickinson, L L; Amin, J J; Else, L L; Boffito, M M; Egan, D D; Owen, A A; Khoo, S S; Back, D D; Orrell, C C; Clarke, A A; Losso, M M; Phanuphak, P P; Carey, D D; Cooper, D A DA; Emery, S S; Puls, R R; ,
CYP2B6*6, CYP2B6*18, Body weight and sex are predictors of efavirenz pharmacokinetics and treatment response: population pharmacokinetic modeling in an HIV/AIDS and TB cohort in Zimbabwe.
Bmc Pharmacology & Toxicology
Dhoro, Milcah M; Zvada, Simbarashe S; Ngara, Bernard B; Nhachi, Charles C; Kadzirange, Gerald G; Chonzi, Prosper P; Masimirembwa, Collen C
Modest but variable effect of rifampin on steady-state plasma pharmacokinetics of efavirenz in healthy African-American and Caucasian volunteers.
Antimicrobial Agents And Chemotherapy
Kwara, Awewura A; Tashima, Karen T KT; Dumond, Julie B JB; Poethke, Pamela P; Kurpewski, Jaclyn J; Kashuba, Angela D M AD; Court, Michael H MH; Greenblatt, David J DJ