CYP2A6 c.479T>A ;(p.L160H)

Variant ID: 19-41354533-A-T

NM_000762.5(CYP2A6):c.479T>A;(p.L160H)

This variant was identified in 124 publications

View GRCh38 version.




Publications:


The Influence of Cytochrome P450 Polymorphisms on Pharmacokinetic Profiles and Treatment Outcomes Among Malaria Patients in Sub-Saharan Africa: A Systematic Review.

Pharmacogenomics And Personalized Medicine
Marwa, Karol J KJ; Kapesa, Anthony A; Kamugisha, Erasmus E; Swedberg, Göte G
Publication Date: 2023

Variant appearance in text: rs1801272
PubMed Link: 37223718
Variant Present in the following documents:
  • Main text
  • pgpm-16-449.pdf
View BVdb publication page



Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23

Variant appearance in text: CYP2A6: 479T>A; Leu160His
PubMed Link: 36823319
Variant Present in the following documents:
  • 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6
View BVdb publication page



Contribution of Genetic Polymorphisms in Human Health.

International Journal Of Environmental Research And Public Health
Chiarella, Pieranna P; Capone, Pasquale P; Sisto, Renata R
Publication Date: 2023-01-04

Variant appearance in text: rs1801272
PubMed Link: 36673670
Variant Present in the following documents:
  • ijerph-20-00912.pdf
View BVdb publication page



Coumarin-Induced Hepatotoxicity: A Narrative Review.

Molecules (Basel, Switzerland)
Pitaro, Michele M; Croce, Nicoletta N; Gallo, Valentina V; Arienzo, Alyexandra A; Salvatore, Giulia G; Antonini, Giovanni G
Publication Date: 2022-12-19

Variant appearance in text: CYP2A6: Leu160His
PubMed Link: 36558195
Variant Present in the following documents:
  • Main text
View BVdb publication page



Clinical assessment for diet prescription.

Journal Of Preventive Medicine And Hygiene
Kiani, Aysha Karim AK; Medori, Maria Chiara MC; Dhuli, Kristjana K; Donato, Kevin K; Caruso, Paola P; Fioretti, Francesco F; Perrone, Marco Alfonso MA; Ceccarini, Maria Rachele MR; Manganotti, Paolo P; Nodari, Savina S; Codini, Michela M; Beccari, Tommaso T; Bertelli, Matteo M
Publication Date: 2022-06

Variant appearance in text: rs1801272
PubMed Link: 36479490
Variant Present in the following documents:
  • Main text
  • jpmh-2022-02-e102.pdf
View BVdb publication page



Association between gene polymorphisms in the cyclophosphamide metabolism pathway with complications after haploidentical hematopoietic stem cell transplantation.

Frontiers In Immunology
Muñiz, Paula P; Andrés-Zayas, Cristina C; Carbonell, Diego D; Chicano, María M; Bailén, Rebeca R; Oarbeascoa, Gillen G; Suárez-González, Julia J; Gómez Centurión, Ignacio I; Dorado, Nieves N; Gallardo, David D; Anguita, Javier J; Kwon, Mi M; Díez-Martín, Jose L JL; Martínez-Laperche, Carolina C; Buño, Ismael I
Publication Date: 2022

Variant appearance in text: rs1801272
PubMed Link: 36211438
Variant Present in the following documents:
  • Table_1.xlsx, sheet 1
View BVdb publication page



The genetic landscape of major drug metabolizing cytochrome P450 genes-an updated analysis of population-scale sequencing data.

The Pharmacogenomics Journal
Zhou, Yitian Y; Lauschke, Volker M VM
Publication Date: 2022-12

Variant appearance in text: CYP2A6: L160H; rs1801272
PubMed Link: 36068297
Variant Present in the following documents:
  • Main text
  • 41397_2022_Article_288.pdf
View BVdb publication page



Dopamine DRD2 and DRD3 Polymorphisms Involvement in Nicotine Dependence in Patients with Treatment-Resistant Mental Disorders.

Journal Of Personalized Medicine
Del Casale, Antonio A; Paolini, Marco M; Gentile, Giovanna G; Borro, Marina M; Zocchi, Clarissa C; Fiaschè, Federica F; Padovano, Alessio A; Zoppi, Teodolinda T; Modesti, Martina Nicole MN; De Luca, Ottavia O; Pomes, Leda Marina LM; Brugnoli, Roberto R; Ferracuti, Stefano S; Girardi, Paolo P; Pompili, Maurizio M; Simmaco, Maurizio M
Publication Date: 2022-04-02

Variant appearance in text: rs1801272
PubMed Link: 35455685
Variant Present in the following documents:
  • Main text
  • jpm-12-00565.pdf
View BVdb publication page



CYP2C19 plays a major role in the hepatic N-oxidation of cotinine.

Drug Metabolism And Disposition: The Biological Fate Of Chemicals
Perez-Paramo, Yadira X YX; Watson, Christy J W CJW; Chen, Gang G; Lazarus, Philip P
Publication Date: 2022-02-23

Variant appearance in text: rs1801272
PubMed Link: 35197312
Variant Present in the following documents:
  • Main text
  • dmd.121.000624.pdf
View BVdb publication page



Analysis of Very Important Pharmacogenomics Variants in the Chinese Lahu Population.

Pharmacogenomics And Personalized Medicine
Cheng, Yujing Y; Li, Qi Q; Yang, Xin X; Ding, Heng H; Chen, Wanlu W; Dai, Run R; Zhang, Chan C
Publication Date: 2021

Variant appearance in text: rs1801272
PubMed Link: 34629888
Variant Present in the following documents:
  • Main text
  • pgpm-14-1275.pdf
View BVdb publication page



Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

Translational And Clinical Pharmacology
Kim, Byungwook B; Yoon, Deok Yong DY; Lee, SeungHwan S; Jang, In-Jin IJ; Yu, Kyung-Sang KS; Cho, Joo-Youn JY; Oh, Jaeseong J
Publication Date: 2021-09

Variant appearance in text: CYP2A6: L160H; rs1801272
PubMed Link: 34621706
Variant Present in the following documents:
  • tcp-29-135-s001.xls, sheet 1
View BVdb publication page



Functional characterization of novel rare CYP2A6 variants and potential implications for clinical outcomes.

Clinical And Translational Science
El-Boraie, Ahmed A; Tanner, Julie-Anne JA; Zhu, Andy Z X AZX; Claw, Katrina G KG; Prasad, Bhagwat B; Schuetz, Erin G EG; Thummel, Kenneth E KE; Fukunaga, Koya K; Mushiroda, Taisei T; Kubo, Michiaki M; Benowitz, Neal L NL; Lerman, Caryn C; Tyndale, Rachel F RF
Publication Date: 2022-01

Variant appearance in text: CYP2A6: L160H
PubMed Link: 34476898
Variant Present in the following documents:
  • CTS-15-204-s001.pdf
  • CTS-15-204.pdf
View BVdb publication page



Functional characterization of novel rare CYP2A6 variants and potential implications for clinical outcomes.

Clinical And Translational Science
El-Boraie, Ahmed A; Tanner, Julie-Anne JA; Zhu, Andy Z X AZX; Claw, Katrina G KG; Prasad, Bhagwat B; Schuetz, Erin G EG; Thummel, Kenneth E KE; Fukunaga, Koya K; Mushiroda, Taisei T; Kubo, Michiaki M; Benowitz, Neal L NL; Lerman, Caryn C; Tyndale, Rachel F RF
Publication Date: 2021-09-03

Variant appearance in text: CYP2A6: L160H
PubMed Link: 34476898
Variant Present in the following documents:
  • CTS-15-204-s001.pdf
  • CTS-15-204.pdf
View BVdb publication page



Molecular and functional profiling identifies therapeutically targetable vulnerabilities in plasmablastic lymphoma.

Nature Communications
Frontzek, Fabian F; Staiger, Annette M AM; Zapukhlyak, Myroslav M; Xu, Wendan W; Bonzheim, Irina I; Borgmann, Vanessa V; Sander, Philip P; Baptista, Maria Joao MJ; Heming, Jan-Niklas JN; Berning, Philipp P; Wullenkord, Ramona R; Erdmann, Tabea T; Lutz, Mathias M; Veratti, Pia P; Ehrenfeld, Sophia S; Wienand, Kirsty K; Horn, Heike H; Goodlad, John R JR; Wilson, Matthew R MR; Anagnostopoulos, Ioannis I; Lamping, Mario M; Gonzalez-Barca, Eva E; Climent, Fina F; Salar, Antonio A; Castellvi, Josep J; Abrisqueta, Pau P; Menarguez, Javier J; Aldamiz, Teresa T; Richter, Julia J; Klapper, Wolfram W; Tzankov, Alexandar A; Dirnhofer, Stefan S; Rosenwald, Andreas A; Mate, José Luis JL; Tapia, Gustavo G; Lenz, Peter P; Miething, Cornelius C; Hartmann, Wolfgang W; Chapuy, Björn B; Fend, Falko F; Ott, German G; Navarro, José-Tomas JT; Grau, Michael M; Lenz, Georg G
Publication Date: 2021-08-31

Variant appearance in text: CYP2A6: 479T>A; L160H; rs1801272
PubMed Link: 34465776
Variant Present in the following documents:
  • 41467_2021_25405_MOESM7_ESM.xlsx, sheet 2
View BVdb publication page



Individualized Drugs' Selection by Evaluation of Drug Properties, Pharmacogenomics and Clinical Parameters: Performance of a Bioinformatic Tool Compared to a Clinically Established Counselling Process.

Pharmacogenomics And Personalized Medicine
Borro, Marina M; Gentile, Giovanna G; Preissner, Sally H SH; Pomes, Leda Marina LM; Gohlke, Björn-Oliver BO; Del Casale, Antonio A; Eckert, Andreas A; Marchetti, Paolo P; Preissner, Saskia S; Preissner, Robert R; Simmaco, Maurizio M
Publication Date: 2021

Variant appearance in text: rs1801272
PubMed Link: 34385834
Variant Present in the following documents:
  • Main text
  • pgpm-14-955.pdf
View BVdb publication page



Genetic Variants in Smoking-Related Genes in Two Smoking Cessation Programs: A Cross-Sectional Study.

International Journal Of Environmental Research And Public Health
Pérez-Rubio, Gloria G; López-Flores, Luis Alberto LA; Cupertino, Ana Paula AP; Cartujano-Barrera, Francisco F; Reynales-Shigematsu, Luz Myriam LM; Ramírez, Mariana M; Ellerbeck, Edward F EF; Rodríguez-Bolaños, Rosibel R; Falfan-Valencia, Ramcés R
Publication Date: 2021-06-19

Variant appearance in text: rs1801272
PubMed Link: 34205269
Variant Present in the following documents:
  • Main text
  • ijerph-18-06597.pdf
View BVdb publication page



HIV-1 and human genetic variation.

Nature Reviews. Genetics
McLaren, Paul J PJ; Fellay, Jacques J
Publication Date: 2021-10

Variant appearance in text: rs1801272
PubMed Link: 34168330
Variant Present in the following documents:
  • Main text
View BVdb publication page



Functional Gene Variants in Chronic Obstructive Pulmonary Disease: The Search Continues.

American Journal Of Respiratory Cell And Molecular Biology
Acunzo, Mario M; Nana-Sinkam, Patrick P
Publication Date: 2021-07

Variant appearance in text: rs1801272
PubMed Link: 33945772
Variant Present in the following documents:
  • Main text
View BVdb publication page



Biochemistry of nicotine metabolism and its relevance to lung cancer.

The Journal Of Biological Chemistry
Murphy, Sharon E SE
Publication Date: 2021

Variant appearance in text: CYP2A6: L160H; rs1801272
PubMed Link: 33932402
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic Factors Associated with COPD Depend on the Ancestral Caucasian/Amerindian Component in the Mexican Population.

Diagnostics (Basel, Switzerland)
Pérez-Rubio, Gloria G; Falfán-Valencia, Ramcés R; Fernández-López, Juan Carlos JC; Ramírez-Venegas, Alejandra A; Hernández-Zenteno, Rafael de Jesús RJ; Flores-Trujillo, Fernando F; Silva-Zolezzi, Irma I
Publication Date: 2021-03-27

Variant appearance in text: rs1801272
PubMed Link: 33801584
Variant Present in the following documents:
  • Main text
  • diagnostics-11-00599.pdf
View BVdb publication page



Genetic Diversity of Drug-Related Genes in Native Americans of the Brazilian Amazon.

Pharmacogenomics And Personalized Medicine
Fernandes, Marianne Rodrigues MR; Rodrigues, Juliana Carla Gomes JCG; Maroñas, Olalla O; Latorre-Pellicer, Ana A; Cruz, Raquel R; Guerreiro, João Farias JF; Burbano, Rommel Mario Rodriguez RMR; de Assumpção, Paulo Pimentel PP; Ribeiro-Dos-Santos, Andrea A; Dos Santos, Sidney Emanuel Batista SEB; Carracedo, Angel A; Dos Santos, Ney Pereira Carneiro NPC
Publication Date: 2021

Variant appearance in text: rs1801272
PubMed Link: 33519226
Variant Present in the following documents:
  • Main text
View BVdb publication page



Deregulated Immune Pathway Associated with Palbociclib Resistance in Preclinical Breast Cancer Models: Integrative Genomics and Transcriptomics.

Genes
Pandey, Kamal K; Lee, Eunbyeol E; Park, Nahee N; Hur, Jin J; Cho, Young Bin YB; Katuwal, Nar Bahadur NB; Kim, Seung Ki SK; Lee, Seung Ah SA; Kim, Isaac I; An, Hee Jung HJ; Hwang, Sohyun S; Moon, Yong Wha YW
Publication Date: 2021-01-25

Variant appearance in text: CYP2A6: L160H
PubMed Link: 33504001
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetics of 35 blood and urine biomarkers in the UK Biobank.

Nature Genetics
Sinnott-Armstrong, Nasa N; Tanigawa, Yosuke Y; Amar, David D; Mars, Nina N; Benner, Christian C; Aguirre, Matthew M; Venkataraman, Guhan Ram GR; Wainberg, Michael M; Ollila, Hanna M HM; Kiiskinen, Tuomo T; Havulinna, Aki S AS; Pirruccello, James P JP; Qian, Junyang J; Shcherbina, Anna A; , ; Rodriguez, Fatima F; Assimes, Themistocles L TL; Agarwala, Vineeta V; Tibshirani, Robert R; Hastie, Trevor T; Ripatti, Samuli S; Pritchard, Jonathan K JK; Daly, Mark J MJ; Rivas, Manuel A MA
Publication Date: 2021-02

Variant appearance in text: CYP2A6: 479T>A; Leu160His; rs1801272
PubMed Link: 33462484
Variant Present in the following documents:
  • NIHMS1651539-supplement-2.xlsx, sheet 21
View BVdb publication page



Influence of CYP4F2, ApoE, and CYP2A6 gene polymorphisms on the variability of Warfarin dosage requirements and susceptibility to cardiovascular disease in Jordan.

International Journal Of Medical Sciences
Al-Eitan, Laith N LN; Almasri, Ayah Y AY; Alnaamneh, Adan H AH; Aman, Hatem A HA; Alrabadi, Nasr N NN; Khasawneh, Rame H RH; Alghamdi, Mansour A MA
Publication Date: 2021

Variant appearance in text: rs1801272
PubMed Link: 33437219
Variant Present in the following documents:
  • Main text
  • ijmsv18p0826.pdf
View BVdb publication page



How Can Drug Metabolism and Transporter Genetics Inform Psychotropic Prescribing?

Frontiers In Genetics
Carvalho Henriques, Beatriz B; Yang, Esther H EH; Lapetina, Diego D; Carr, Michael S MS; Yavorskyy, Vasyl V; Hague, Joshua J; Aitchison, Katherine J KJ
Publication Date: 2020

Variant appearance in text: CYP2A6: Leu160His; rs1801272
PubMed Link: 33363564
Variant Present in the following documents:
  • Main text
View BVdb publication page



Variation in 100 relevant pharmacogenes among emiratis with insights from understudied populations.

Scientific Reports
Al-Mahayri, Zeina N ZN; Patrinos, George P GP; Wattanapokayakit, Sukanya S; Iemwimangsa, Nareenart N; Fukunaga, Koya K; Mushiroda, Taisei T; Chantratita, Wasun W; Ali, Bassam R BR
Publication Date: 2020-12-04

Variant appearance in text: rs1801272
PubMed Link: 33277594
Variant Present in the following documents:
  • 41598_2020_78231_MOESM1_ESM.pdf
View BVdb publication page



Abstracts from the 53rd European Society of Human Genetics (ESHG) Conference: e-Posters.

European Journal Of Human Genetics : Ejhg
Publication Date: 2020-12

Variant appearance in text: rs1801272
PubMed Link: 33262486
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pleiotropic Functions of Cytochrome P450 Monooxygenase-Derived Eicosanoids in Cancer.

Frontiers In Pharmacology
Luo, Ying Y; Liu, Jun-Yan JY
Publication Date: 2020

Variant appearance in text: CYP2A6: L160H; rs1801272
PubMed Link: 33192522
Variant Present in the following documents:
  • Main text
View BVdb publication page



Study of a supplement and a genetic test for lymphedema management.

Acta Bio-Medica : Atenei Parmensis
Michelini, Sandro S; Cestari, Marina M; Michelini, Serena S; Camilleri, Giorgio G; De Antoni, Luca L; Sonna, Willy Nelson WN; Bertelli, Matteo M
Publication Date: 2020-11-09

Variant appearance in text: rs1801272
PubMed Link: 33170163
Variant Present in the following documents:
  • Main text
  • ACTA-91-13.pdf
View BVdb publication page



Analysis of Comprehensive Pharmacogenomic Profiling of VIP Variants Among the Genetically Isolated Chechen Subpopulation from Jordan.

Pharmacogenomics And Personalized Medicine
Al-Eitan, Laith N LN; Rababa'h, Doaa M DM; Hakooz, Nancy M NM; Alghamdi, Mansour A MA; Dajani, Rana B RB
Publication Date: 2020

Variant appearance in text: rs1801272
PubMed Link: 32765042
Variant Present in the following documents:
  • Main text
  • pgpm-13-199.pdf
View BVdb publication page



Population Pharmacokinetic and Pharmacogenetic Analysis of Mitotane in Patients with Adrenocortical Carcinoma: Towards Individualized Dosing.

Clinical Pharmacokinetics
Yin, Anyue A; Ettaieb, Madeleine H T MHT; Swen, Jesse J JJ; van Deun, Liselotte L; Kerkhofs, Thomas M A TMA; van der Straaten, Robert J H M RJHM; Corssmit, Eleonora P M EPM; Gelderblom, Hans H; Kerstens, Michiel N MN; Feelders, Richard A RA; Eekhoff, Marelise M; Timmers, Henri J L M HJLM; D'Avolio, Antonio A; Cusato, Jessica J; Guchelaar, Henk-Jan HJ; Haak, Harm R HR; Moes, Dirk Jan A R DJAR
Publication Date: 2021-01

Variant appearance in text: CYP2A6: L160H; rs1801272
PubMed Link: 32607875
Variant Present in the following documents:
  • 40262_2020_913_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Genetic polymorphisms of pharmacogenomic VIP variants in the Dai population from Yunnan province.

Molecular Genetics & Genomic Medicine
Cheng, Yujing Y; Dai, Run R; Chen, Wanlu W; Li, Qi Q; Zhang, Chan C; Yang, Tonghua T
Publication Date: 2020-07

Variant appearance in text: rs1801272
PubMed Link: 32347657
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-wide association meta-analysis of nicotine metabolism and cigarette consumption measures in smokers of European descent.

Molecular Psychiatry
Buchwald, Jadwiga J; Chenoweth, Meghan J MJ; Palviainen, Teemu T; Zhu, Gu G; Benner, Christian C; Gordon, Scott S; Korhonen, Tellervo T; Ripatti, Samuli S; Madden, Pamela A F PAF; Lehtimäki, Terho T; Raitakari, Olli T OT; Salomaa, Veikko V; Rose, Richard J RJ; George, Tony P TP; Lerman, Caryn C; Pirinen, Matti M; Martin, Nicholas G NG; Kaprio, Jaakko J; Loukola, Anu A; Tyndale, Rachel F RF
Publication Date: 2021-06

Variant appearance in text: rs1801272
PubMed Link: 32157176
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-wide association meta-analysis of nicotine metabolism and cigarette consumption measures in smokers of European descent.

Molecular Psychiatry
Buchwald, Jadwiga J; Chenoweth, Meghan J MJ; Palviainen, Teemu T; Zhu, Gu G; Benner, Christian C; Gordon, Scott S; Korhonen, Tellervo T; Ripatti, Samuli S; Madden, Pamela A F PAF; Lehtimäki, Terho T; Raitakari, Olli T OT; Salomaa, Veikko V; Rose, Richard J RJ; George, Tony P TP; Lerman, Caryn C; Pirinen, Matti M; Martin, Nicholas G NG; Kaprio, Jaakko J; Loukola, Anu A; Tyndale, Rachel F RF
Publication Date: 2021-06

Variant appearance in text: rs1801272
PubMed Link: 32157176
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic Polymorphisms of Pharmacogenes among the Genetically Isolated Circassian Subpopulation from Jordan.

Journal Of Personalized Medicine
Al-Eitan, Laith N LN; Rababa'h, Doaa M DM; Hakooz, Nancy M NM; Alghamdi, Mansour A MA; Dajani, Rana B RB
Publication Date: 2020-01-06

Variant appearance in text: rs1801272
PubMed Link: 31935801
Variant Present in the following documents:
  • Main text
  • jpm-10-00002.pdf
View BVdb publication page



Data on the endogenous conversion of tyrosol into hydroxytyrosol in humans.

Data In Brief
Boronat, Anna A; Mateus, Julian J; Soldevila-Domenech, Natalia N; Guerra, Mercè M; Rodríguez-Morató, Jose J; Varon, Carlota C; Muñoz, Daniel D; Barbosa, Francina F; Morales, Juan Carlos JC; Gaedigk, Andreas A; Langohr, Klaus K; Covas, Maria-Isabel MI; Pérez-Mañá, Clara C; Fitó, Montserrat M; Tyndale, Rachel F RF; de la Torre, Rafael R
Publication Date: 2019-12

Variant appearance in text: CYP2A6: Leu160His; rs1801272
PubMed Link: 31788516
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



POT1 and Damage Response Malfunction Trigger Acquisition of Somatic Activating Mutations in the VEGF Pathway in Cardiac Angiosarcomas.

Journal Of The American Heart Association
Calvete, Oriol O; Garcia-Pavia, Pablo P; Domínguez, Fernando F; Mosteiro, Lluc L; Pérez-Cabornero, Lucía L; Cantalapiedra, Diego D; Zorio, Esther E; Ramón Y Cajal, Teresa T; Crespo-Leiro, Maria G MG; Teulé, Álex Á; Lázaro, Conxi C; Morente, Manuel M MM; Urioste, Miguel M; Benitez, Javier J
Publication Date: 2019-09-17

Variant appearance in text: rs1801272
PubMed Link: 31510873
Variant Present in the following documents:
  • JAH3-8-e012875-s001.pdf
  • JAH3-8-e012875.pdf
View BVdb publication page



Genetic polymorphisms analysis of pharmacogenomic VIP variants in Bai ethnic group from China.

Molecular Genetics & Genomic Medicine
Chen, Wanlu W; Ding, Heng H; Cheng, Yujing Y; Li, Qi Q; Dai, Run R; Yang, Xin X; Zhang, Chan C
Publication Date: 2019-09

Variant appearance in text: rs1801272
PubMed Link: 31361092
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic analysis of pharmacogenomic VIP variants in the Blang population from Yunnan Province of China.

Molecular Genetics & Genomic Medicine
Zhang, Chan C; Guo, Weiwei W; Cheng, Yujing Y; Li, Qi Q; Yang, Xin X; Dai, Run R; Zhu, Linhao L; Chen, Wanlu W
Publication Date: 2019-05

Variant appearance in text: CYP2A6: Leu160His; rs1801272
PubMed Link: 30955239
Variant Present in the following documents:
  • Main text
  • MGG3-7-e574.pdf
View BVdb publication page



Evaluation of a weighted genetic risk score for the prediction of biomarkers of CYP2A6 activity.

Addiction Biology
El-Boraie, Ahmed A; Taghavi, Taraneh T; Chenoweth, Meghan J MJ; Fukunaga, Koya K; Mushiroda, Taisei T; Kubo, Michiaki M; Lerman, Caryn C; Nollen, Nicole L NL; Benowitz, Neal L NL; Tyndale, Rachel F RF
Publication Date: 2020-01

Variant appearance in text: CYP2A6: L160H; rs1801272
PubMed Link: 30815984
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic polymorphisms of pharmacogenomic VIP variants in the Lisu population of southwestern China: A cohort study.

Medicine
Li, Bin B; Wang, Li L; Lei, Lingyu L; Zhang, Mingxiang M; Niu, Fanglin F; Chen, Peng P; Jin, Tianbo T
Publication Date: 2018-09

Variant appearance in text: CYP2A6: Leu160His; rs1801272
PubMed Link: 30235667
Variant Present in the following documents:
  • medi-97-e12231.pdf
View BVdb publication page



Whole genome sequencing identifies high-impact variants in well-known pharmacogenomic genes.

The Pharmacogenomics Journal
Choi, Jihoon J; Tantisira, Kelan G KG; Duan, Qing Ling QL
Publication Date: 2019-04

Variant appearance in text: rs1801272
PubMed Link: 30214008
Variant Present in the following documents:
  • NIHMS1503453-supplement-3.xlsx, sheet 1
View BVdb publication page



Association of genetic polymorphisms CYP2A6*2 rs1801272 and CYP2A6*9 rs28399433 with tobacco-induced lung Cancer: case-control study in an Egyptian population.

Bmc Cancer
Ezzeldin, Nada N; El-Lebedy, Dalia D; Darwish, Amira A; El Bastawisy, Ahmed A; Abd Elaziz, Shereen Hamdy SH; Hassan, Mirhane Mohamed MM; Saad-Hussein, Amal A
Publication Date: 2018-05-03

Variant appearance in text: rs1801272
PubMed Link: 29724170
Variant Present in the following documents:
  • Main text
  • 12885_2018_Article_4342.pdf
View BVdb publication page



Genetic polymorphisms in very important pharmacogenomic variants in the Zhuang ethnic group of Southwestern China: A cohort study in the Zhuang population.

Medicine
Li, Jing J; Guo, Chenghao C; Yan, Mengdan M; Niu, Fanglin F; Chen, Peng P; Li, Bin B; Jin, Tianbo T
Publication Date: 2018-04

Variant appearance in text: CYP2A6: Leu160His; rs1801272
PubMed Link: 29703042
Variant Present in the following documents:
  • medi-97-e0559.pdf
View BVdb publication page



Genetic variation in biotransformation enzymes, air pollution exposures, and risk of spina bifida.

American Journal Of Medical Genetics. Part A
Padula, Amy M AM; Yang, Wei W; Schultz, Kathleen K; Lurmann, Fred F; Hammond, S Katharine SK; Shaw, Gary M GM
Publication Date: 2018-05

Variant appearance in text: rs1801272
PubMed Link: 29681089
Variant Present in the following documents:
  • Main text
View BVdb publication page



Cardiac arrhythmia and neuroexcitability gene variants in resected brain tissue from patients with sudden unexpected death in epilepsy (SUDEP).

Npj Genomic Medicine
Friedman, Daniel D; Kannan, Kasthuri K; Faustin, Arline A; Shroff, Seema S; Thomas, Cheddhi C; Heguy, Adriana A; Serrano, Jonathan J; Snuderl, Matija M; Devinsky, Orrin O
Publication Date: 2018

Variant appearance in text: CYP2A6: L160H; rs1801272
PubMed Link: 29619247
Variant Present in the following documents:
  • 41525_2018_48_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



Actionable perturbations of damage responses by TCL1/ATM and epigenetic lesions form the basis of T-PLL.

Nature Communications
Schrader, A A; Crispatzu, G G; Oberbeck, S S; Mayer, P P; Pützer, S S; von Jan, J J; Vasyutina, E E; Warner, K K; Weit, N N; Pflug, N N; Braun, T T; Andersson, E I EI; Yadav, B B; Riabinska, A A; Maurer, B B; Ventura Ferreira, M S MS; Beier, F F; Altmüller, J J; Lanasa, M M; Herling, C D CD; Haferlach, T T; Stilgenbauer, S S; Hopfinger, G G; Peifer, M M; Brümmendorf, T H TH; Nürnberg, P P; Elenitoba-Johnson, K S J KSJ; Zha, S S; Hallek, M M; Moriggl, R R; Reinhardt, H C HC; Stern, M-H MH; Mustjoki, S S; Newrzela, S S; Frommolt, P P; Herling, M M
Publication Date: 2018-02-15

Variant appearance in text: CYP2A6: L160H; rs1801272
PubMed Link: 29449575
Variant Present in the following documents:
  • 41467_2017_2688_MOESM14_ESM.xls, sheet 3
View BVdb publication page



P450 Pharmacogenetics in Indigenous North American Populations.

Journal Of Personalized Medicine
Henderson, Lindsay M LM; Claw, Katrina G KG; Woodahl, Erica L EL; Robinson, Renee F RF; Boyer, Bert B BB; Burke, Wylie W; Thummel, Kenneth E KE
Publication Date: 2018-02-01

Variant appearance in text: rs1801272
PubMed Link: 29389890
Variant Present in the following documents:
  • Main text
View BVdb publication page



An integrative functional genomics framework for effective identification of novel regulatory variants in genome-phenome studies.

Genome Medicine
Zhao, Junfei J; Cheng, Feixiong F; Jia, Peilin P; Cox, Nancy N; Denny, Joshua C JC; Zhao, Zhongming Z
Publication Date: 2018-01-29

Variant appearance in text: CYP2A6: L160H; rs1801272
PubMed Link: 29378629
Variant Present in the following documents:
  • 13073_2018_513_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Pharmacokinetic characterization of three novel 4-mg nicotine lozenges
.

International Journal Of Clinical Pharmacology And Therapeutics
Sukhija, Manpreet M; Srivastava, Reena R; Kaushik, Aditya A
Publication Date: 2018-03

Variant appearance in text: rs1801272
PubMed Link: 29350176
Variant Present in the following documents:
  • Main text
  • intjclinpharmacol-56-113.pdf
View BVdb publication page



Genetic variation in human drug-related genes.

Genome Medicine
Schärfe, Charlotta Pauline Irmgard CPI; Tremmel, Roman R; Schwab, Matthias M; Kohlbacher, Oliver O; Marks, Debora Susan DS
Publication Date: 2017-12-22

Variant appearance in text: rs1801272
PubMed Link: 29273096
Variant Present in the following documents:
  • 13073_2017_502_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



Novel CYP2A6 diplotypes identified through next-generation sequencing are associated with in-vitro and in-vivo nicotine metabolism.

Pharmacogenetics And Genomics
Tanner, Julie-Anne JA; Zhu, Andy Z AZ; Claw, Katrina G KG; Prasad, Bhagwat B; Korchina, Viktoriya V; Hu, Jianhong J; Doddapaneni, HarshaVardhan H; Muzny, Donna M DM; Schuetz, Erin G EG; Lerman, Caryn C; Thummel, Kenneth E KE; Scherer, Steven E SE; Tyndale, Rachel F RF
Publication Date: 2018-01

Variant appearance in text: rs1801272
PubMed Link: 29232328
Variant Present in the following documents:
  • Main text
View BVdb publication page



Variation in CYP2A6 Activity and Personalized Medicine.

Journal Of Personalized Medicine
Tanner, Julie-Anne JA; Tyndale, Rachel F RF
Publication Date: 2017-12-01

Variant appearance in text: CYP2A6: L160H; rs1801272
PubMed Link: 29194389
Variant Present in the following documents:
  • Main text
  • jpm-07-00018.pdf
View BVdb publication page



Data on polymorphisms in CYP2A6 associated to risk and predispose to smoking related variables.

Data In Brief
López-Flores, Luis A LA; Pérez-Rubio, Gloria G; Ramírez-Venegas, Alejandra A; Ambrocio-Ortiz, Enrique E; Sansores, Raúl H RH; Falfán-Valencia, Ramcés R
Publication Date: 2017-12

Variant appearance in text: rs1801272
PubMed Link: 28971126
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page