Pharmacokinetic modeling of R and S-Methadone and their metabolites to study the effects of various covariates in post-operative children.
Cpt: Pharmacometrics & Systems Pharmacology
Aruldhas, Blessed W BW; Quinney, Sara K SK; Overholser, Brian R BR; Heathman, Michael A MA; Masters, Andrea R AR; Ly, Reynold C RC; Gao, Hongyu H; Packiasabapathy, Senthil S; Sadhasivam, Senthilkumar S
Pharmacogenomics of methadone: a narrative review of the literature.
Pharmacogenomics
Packiasabapathy, Senthil S; Aruldhas, Blessed W BW; Horn, Nicole N; Overholser, Brian R BR; Quinney, Sara K SK; Renschler, Janelle S JS; Sadhasivam, Senthilkumar S
Genome-Wide Pharmacogenomic Study on Methadone Maintenance Treatment Identifies SNP rs17180299 and Multiple Haplotypes on CYP2B6, SPON1, and GSG1L Associated with Plasma Concentrations of Methadone R- and S-enantiomers in Heroin-Dependent Patients.