CYP2B6 c.171+6023A>T

Variant ID: 19-41503404-A-T

NM_000767.4(CYP2B6):c.171+6023A>T

This variant was identified in 8 publications

View GRCh38 version.




Publications:


Pharmacokinetic modeling of R and S-Methadone and their metabolites to study the effects of various covariates in post-operative children.

Cpt: Pharmacometrics & Systems Pharmacology
Aruldhas, Blessed W BW; Quinney, Sara K SK; Overholser, Brian R BR; Heathman, Michael A MA; Masters, Andrea R AR; Ly, Reynold C RC; Gao, Hongyu H; Packiasabapathy, Senthil S; Sadhasivam, Senthilkumar S
Publication Date: 2021-10

Variant appearance in text: rs7250601
PubMed Link: 34435753
Variant Present in the following documents:
  • Main text
  • PSP4-10-1183.pdf
View BVdb publication page



Novel associations between CYP2B6 polymorphisms, perioperative methadone metabolism and clinical outcomes in children.

Pharmacogenomics
Packiasabapathy, Senthil S; Aruldhas, Blessed W BW; Zhang, Pengyue P; Overholser, Brian R BR; Quinney, Sara K SK; Sadhasivam, Senthilkumar S
Publication Date: 2021-07

Variant appearance in text: rs7250601
PubMed Link: 34100292
Variant Present in the following documents:
  • Main text
  • pgs-22-591.pdf
View BVdb publication page



Pharmacogenetics of tenofovir and emtricitabine penetration into cerebrospinal fluid.

Southern African Journal Of Hiv Medicine
Decloedt, Eric H EH; Sinxadi, Phumla Z PZ; Wiesner, Lubbe L; Joska, John A JA; Haas, David W DW; Maartens, Gary G
Publication Date: 2021

Variant appearance in text: rs7250601
PubMed Link: 34007475
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacogenomics of methadone: a narrative review of the literature.

Pharmacogenomics
Packiasabapathy, Senthil S; Aruldhas, Blessed W BW; Horn, Nicole N; Overholser, Brian R BR; Quinney, Sara K SK; Renschler, Janelle S JS; Sadhasivam, Senthilkumar S
Publication Date: 2020-08

Variant appearance in text: rs7250601
PubMed Link: 32705966
Variant Present in the following documents:
  • Main text
View BVdb publication page



Whole genome sequencing identifies high-impact variants in well-known pharmacogenomic genes.

The Pharmacogenomics Journal
Choi, Jihoon J; Tantisira, Kelan G KG; Duan, Qing Ling QL
Publication Date: 2019-04

Variant appearance in text: rs7250601
PubMed Link: 30214008
Variant Present in the following documents:
  • NIHMS1503453-supplement-3.xlsx, sheet 1
View BVdb publication page



Effects of cytochrome P450 single nucleotide polymorphisms on methadone metabolism and pharmacodynamics.

Biochemical Pharmacology
Ahmad, Taha T; Valentovic, Monica A MA; Rankin, Gary O GO
Publication Date: 2018-07

Variant appearance in text: rs7250601
PubMed Link: 29458047
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-Wide Pharmacogenomic Study on Methadone Maintenance Treatment Identifies SNP rs17180299 and Multiple Haplotypes on CYP2B6, SPON1, and GSG1L Associated with Plasma Concentrations of Methadone R- and S-enantiomers in Heroin-Dependent Patients.

Plos Genetics
Yang, Hsin-Chou HC; Chu, Shih-Kai SK; Huang, Chieh-Liang CL; Kuo, Hsiang-Wei HW; Wang, Sheng-Chang SC; Liu, Sheng-Wen SW; Ho, Ing-Kang IK; Liu, Yu-Li YL
Publication Date: 2016-03

Variant appearance in text: rs7250601
PubMed Link: 27010727
Variant Present in the following documents:
  • Main text
  • pgen.1005910.pdf
View BVdb publication page



Haplotype structure of CYP2B6 and association with plasma efavirenz concentrations in a Chilean HIV cohort.

The Journal Of Antimicrobial Chemotherapy
Carr, Daniel F DF; la Porte, Charles J L CJ; Pirmohamed, Munir M; Owen, Andrew A; Cortes, Claudia P CP
Publication Date: 2010-09

Variant appearance in text: rs7250601
PubMed Link: 20639527
Variant Present in the following documents:
  • Main text
View BVdb publication page