Publications:

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Whole genome sequencing identifies high-impact variants in well-known pharmacogenomic genes.

The Pharmacogenomics Journal

Choi, Jihoon J; Tantisira, Kelan G KG; Duan, Qing Ling QL

Publication Date: 2019-04

Variant appearance in text: rs4803417

PubMed Link: 30214008

Variant Present in the following documents:

• NIHMS1503453-supplement-3.xlsx, sheet 1

View BVdb publication page

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Polymorphisms in cytochrome P450 are associated with extensive efavirenz pharmacokinetics and CNS toxicities in an HIV cohort in Botswana.

The Pharmacogenomics Journal

Vujkovic, Marijana M; Bellamy, Scarlett L SL; Zuppa, Athena F AF; Gastonguay, Marc R MR; Moorthy, Ganesh S GS; Ratshaa, Bakgaki B; Han, Xiaoyan X; Steenhoff, Andrew P AP; Mosepele, Mosepele M; Strom, Brian L BL; Bisson, Gregory P GP; Aplenc, Richard R; Gross, Robert R

Publication Date: 2018-09

Variant appearance in text: rs4803417

PubMed Link: 29855606

Variant Present in the following documents:

• Main text
• nihms959883.pdf

View BVdb publication page

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Pharmacogenetics of plasma efavirenz exposure in HIV-infected adults and children in South Africa.

British Journal Of Clinical Pharmacology

Sinxadi, Phumla Z PZ; Leger, Paul D PD; McIlleron, Helen M HM; Smith, Peter J PJ; Dave, Joel A JA; Levitt, Naomi S NS; Maartens, Gary G; Haas, David W DW

Publication Date: 2015-07

Variant appearance in text: rs4803417

PubMed Link: 25611810

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetic variation in the CYP2B6 gene is related to circulating 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) concentrations: an observational population-based study.

Environmental Health : A Global Access Science Source

Penell, Johanna J; Lind, Lars L; Fall, Tove T; Syvänen, Anne-Christine AC; Axelsson, Tomas T; Lundmark, Per P; Morris, Andrew P AP; Lindgren, Cecilia C; Mahajan, Anubha A; Salihovic, Samira S; van Bavel, Bert B; Ingelsson, Erik E; Lind, P Monica PM

Publication Date: 2014-05-08

Variant appearance in text: rs4803417

PubMed Link: 24885815

Variant Present in the following documents:

• Main text
• 1476-069X-13-34.pdf

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CYP2B6 non-coding variation associated with smoking cessation is also associated with differences in allelic expression, splicing, and nicotine metabolism independent of common amino-acid changes.

Plos One

Bloom, A Joseph AJ; Martinez, Maribel M; Chen, Li-Shiun LS; Bierut, Laura J LJ; Murphy, Sharon E SE; Goate, Alison A

Publication Date: 2013

Variant appearance in text: rs4803417

PubMed Link: 24260284

Variant Present in the following documents:

• Main text
• pone.0079700.pdf

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Clinical and genetic determinants of plasma nevirapine exposure following an intrapartum dose to prevent mother-to-child HIV transmission.

The Journal Of Infectious Diseases

Vardhanabhuti, Saran S; Acosta, Edward P EP; Ribaudo, Heather J HJ; Severe, Patrice P; Lalloo, Umesh U; Kumarasamy, Nagalingeshwaran N; Taulo, Frank F; Kabanda, Joseph J; Oneko, Olola O; Ive, Prudence P; Sambarey, Pradeep P; Chan, Ellen S ES; Hitti, Jane J; Hong, Francis F; McMahon, Deborah D; Haas, David W DW; ,

Publication Date: 2013-08-15

Variant appearance in text: rs4803417

PubMed Link: 23687222

Variant Present in the following documents:

• Main text

View BVdb publication page

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Multiple genetic variants predict steady-state nevirapine clearance in HIV-infected Cambodians.

Pharmacogenetics And Genomics

Bertrand, Julie J; Chou, Monidarin M; Richardson, Danielle M DM; Verstuyft, Céline C; Leger, Paul D PD; Mentré, France F; Taburet, Anne-Marie AM; Haas, David W DW; ,

Publication Date: 2012-12

Variant appearance in text: rs4803417

PubMed Link: 23104099

Variant Present in the following documents:

• Main text

View BVdb publication page

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Analysis of pharmacogenetic traits in two distinct South African populations.

Human Genomics

Ikediobi, Ogechi O; Aouizerat, Bradley B; Xiao, Yuanyuan Y; Gandhi, Monica M; Gebhardt, Stefan S; Warnich, Louise L

Publication Date: 2011-05

Variant appearance in text: rs4803417

PubMed Link: 21712189

Variant Present in the following documents:

• Main text

View BVdb publication page

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