Publications:

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The Influence of Cytochrome P450 Polymorphisms on Pharmacokinetic Profiles and Treatment Outcomes Among Malaria Patients in Sub-Saharan Africa: A Systematic Review.

Pharmacogenomics And Personalized Medicine

Marwa, Karol J KJ; Kapesa, Anthony A; Kamugisha, Erasmus E; Swedberg, Göte G

Publication Date: 2023

Variant appearance in text: CYP2B6: Q172H; rs3745274

PubMed Link: 37223718

Variant Present in the following documents:

• Main text
• pgpm-16-449.pdf

View BVdb publication page

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Influence of CYP2B6 Genotype on Methadone Dosage in Patients from the Methadone Maintenance Treatment (MMT) Program in Pereira, Colombia.

Life (Basel, Switzerland)

Isaza, Carlos C; Castaño-Ramírez, Oscar Mauricio OM; Vélez, Juan Pablo JP; Henao, Julieta J; Beltrán-Angarita, Leonardo L; Sepúlveda-Arias, Juan Carlos JC

Publication Date: 2023-04-18

Variant appearance in text: rs3745274

PubMed Link: 37109567

Variant Present in the following documents:

• Main text
• life-13-01038.pdf

View BVdb publication page

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An Updated Overview of the Role of CYP450 during Xenobiotic Metabolization in Regulating the Acute Myeloid Leukemia Microenvironment.

International Journal Of Molecular Sciences

Sandoval, Cristian C; Calle, Yolanda Y; Godoy, Karina K; Farías, Jorge J

Publication Date: 2023-03-23

Variant appearance in text: CYP2B6: Q172H

PubMed Link: 37047003

Variant Present in the following documents:

• Main text
• ijms-24-06031.pdf

View BVdb publication page

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Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications

Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA

Publication Date: 2023-04-03

Variant appearance in text: CYP2B6: Q172H

PubMed Link: 37012232

Variant Present in the following documents:

• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2

View BVdb publication page

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Relating CYP2B6 genotype and efavirenz resistance among post-partum women living with HIV with high viremia in Uganda: a nested cross-sectional study.

Aids Research And Therapy

Buzibye, Allan A; Wools-Kaloustian, Kara K; Olagunju, Adeniyi A; Twinomuhwezi, Ellon E; Yiannoutsos, Constantin C; Owen, Andrew A; Neary, Megan M; Matovu, Joshua J; Banturaki, Grace G; Castelnuovo, Barbara B; Lamorde, Mohammed M; Khoo, Saye S; Waitt, Catriona C; Kiragga, Agnes A

Publication Date: 2023-03-31

Variant appearance in text: rs3745274

PubMed Link: 37004096

Variant Present in the following documents:

• Main text
• 12981_2023_Article_514.pdf

View BVdb publication page

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Mechanisms and implications in gene polymorphism mediated diverse reponses to sedatives, analgesics and muscle relaxants.

Korean Journal Of Anesthesiology

Sun, Yan Y; Zhu, Hongyu H; Esmaeili, Elham E; Tang, Xue X; Wu, Zhilin Z

Publication Date: 2022-12-05

Variant appearance in text: CYP2B6: 516G>T; rs3745274

PubMed Link: 36935389

Variant Present in the following documents:

• Main text
• kja-22654.pdf

View BVdb publication page

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Genetic and Non-genetic Factors Influencing Efavirenz Population Pharmacokinetics Among HIV-infected Children in Ethiopia.

Cpt: Pharmacometrics & Systems Pharmacology

Chala, Adugna A; Kitabi, Eliford Ngaimisi EN; Ahmed, Jemal Hussien JH; Tadesse, Birkneh Tilahun BT; Chaka, Tolossa Eticha TE; Makonnen, Eyasu E; Aklillu, Eleni E

Publication Date: 2023-02-24

Variant appearance in text: CYP2B6: 516G>T

PubMed Link: 36840416

Variant Present in the following documents:

• Main text
• PSP4-12-783.pdf

View BVdb publication page

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: CYP2B6: 516G>T; Gln172His

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Effect of common OPRM1, COMT, SLC6A4, ABCB1, and CYP2B6 polymorphisms on perioperative analgesic and propofol demands on patients subjected to thyroidectomy surgery.

Pharmacological Reports : Pr

Soultati, Ioanna I; Ntenti, Charikleia C; Tsaousi, Georgia G; Pourzitaki, Chryssa C; Gkinas, Dimitris D; Thomaidou, Evanthia E; Alexandrakis, Spiros S; Papavramidis, Theodosios T; Goulas, Antonis A

Publication Date: 2023-02-07

Variant appearance in text: CYP2B6: 516G>T; rs3745274

PubMed Link: 36749481

Variant Present in the following documents:

• Main text
• 43440_2023_Article_455.pdf

View BVdb publication page

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Therapeutic and Toxic Effects of Valproic Acid Metabolites.

Metabolites

Shnayder, Natalia A NA; Grechkina, Violetta V VV; Khasanova, Aiperi K AK; Bochanova, Elena N EN; Dontceva, Evgenia A EA; Petrova, Marina M MM; Asadullin, Azat R AR; Shipulin, German A GA; Altynbekov, Kuanysh S KS; Al-Zamil, Mustafa M; Nasyrova, Regina F RF

Publication Date: 2023-01-16

Variant appearance in text: rs3745274

PubMed Link: 36677060

Variant Present in the following documents:

• Main text
• metabolites-13-00134.pdf

View BVdb publication page

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Circulating messenger RNA variants as a potential biomarker for surveillance of hepatocellular carcinoma.

Frontiers In Oncology

Block, Timothy T; Zezulinski, Daniel D; Kaplan, David E DE; Lu, Jingqiao J; Zanine, Samantha S; Zhan, Tingting T; Doria, Cataldo C; Sayeed, Aejaz A

Publication Date: 2022

Variant appearance in text: rs3745274

PubMed Link: 36582804

Variant Present in the following documents:

• Table_6.xlsx, sheet 1

View BVdb publication page

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Variations in the Frequencies of Polymorphisms in the CYP450s Genes in Eight Major Ethnicities of Iran: A Review of the Human Data.

Journal Of Personalized Medicine

Neyshaburinezhad, Navid N; Ghasim, Hengameh H; Rouini, Mohammadreza M; Daali, Youssef Y; Ardakani, Yalda H YH

Publication Date: 2022-11-05

Variant appearance in text: rs3745274

PubMed Link: 36579562

Variant Present in the following documents:

• jpm-12-01848.pdf

View BVdb publication page

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Pharmacogenetics of CYP2A6, CYP2B6, and UGT2B7 in the Context of HIV Treatments in African Populations.

Journal Of Personalized Medicine

Ford, Graeme R GR; Niehaus, Antoinette A; Joubert, Fourie F; Pepper, Michael S MS

Publication Date: 2022-12-05

Variant appearance in text: rs3745274

PubMed Link: 36556234

Variant Present in the following documents:

• Main text
• jpm-12-02013.pdf

View BVdb publication page

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Pathogenesis of Bronchopulmonary Dysplasia: Role of Oxidative Stress from 'Omics' Studies.

Antioxidants (Basel, Switzerland)

Kimble, Ashley A; Robbins, Mary E ME; Perez, Marta M

Publication Date: 2022-12-01

Variant appearance in text: rs3745274

PubMed Link: 36552588

Variant Present in the following documents:

• Main text
• antioxidants-11-02380.pdf

View BVdb publication page

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Establishment and characterization of a new mantle cell lymphoma cell line with a NOTCH2 mutation, Arbo.

Ejhaem

Safa, Firas F; Rasmussen, Terri T; Lobelle-Rich, Patricia P; Collier, Stephanie S; Milligan, Nicholas N; Schmeig, John J; Schmid, Janet J; Wiewiorowski, Carol C; Totaro, Denise D; Brown, Theresa C TC; Satyavarapu, Ishwarya I; Badoo, Melody M; Ungerleider, Nathan N; Flemington, Erik K EK; Safah, Hana H; Saba, Nakhle S NS

Publication Date: 2022-11

Variant appearance in text: rs3745274

PubMed Link: 36467812

Variant Present in the following documents:

• JHA2-3-1326-s001.xlsx, sheet 1

View BVdb publication page

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SNPs in 3'UTR miRNA Target Sequences Associated with Individual Drug Susceptibility.

International Journal Of Molecular Sciences

Rykova, Elena E; Ershov, Nikita N; Damarov, Igor I; Merkulova, Tatiana T

Publication Date: 2022-11-08

Variant appearance in text: rs3745274

PubMed Link: 36430200

Variant Present in the following documents:

• Main text
• ijms-23-13725.pdf

View BVdb publication page

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Pharmacogenes that demonstrate high association evidence according to CPIC, DPWG, and PharmGKB.

Frontiers In Medicine

Alshabeeb, Mohammad A MA; Alyabsi, Mesnad M; Aziz, Mohammad A MA; Abohelaika, Salah S

Publication Date: 2022

Variant appearance in text: rs3745274

PubMed Link: 36388934

Variant Present in the following documents:

• Main text
• fmed-09-1001876.pdf

View BVdb publication page

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Pharmacogenomics in Psychiatry Practice: The Value and the Challenges.

International Journal Of Molecular Sciences

Alchakee, Aminah A; Ahmed, Munazza M; Eldohaji, Leen L; Alhaj, Hamid H; Saber-Ayad, Maha M

Publication Date: 2022-11-03

Variant appearance in text: rs3745274

PubMed Link: 36362270

Variant Present in the following documents:

• Main text
• ijms-23-13485.pdf

View BVdb publication page

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The Role of Single Nucleotide Polymorphisms in Transporter Proteins and the Folate Metabolism Pathway in Delayed Methotrexate Excretion: A Case Report and Literature Review.

Pharmacogenomics And Personalized Medicine

Wang, Jun J; Zhao, Yue-Tao YT; Sun, Meng-Jiao MJ; Chen, Feng F; Guo, Hong-Li HL

Publication Date: 2022

Variant appearance in text: rs3745274

PubMed Link: 36349164

Variant Present in the following documents:

• Main text
• pgpm-15-919.pdf

View BVdb publication page

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Frequency of CYP2B6 Alleles in Major Iranian Ethnicities, Affecting Response to Efavirenz.

Genetics Research

Mardi, Parham P; Tavakoli-Far, Bahareh B; Sheibani Nia, Samira S; Jazayeri, Roshanak R; Houshmand, Massoud M

Publication Date: 2022

Variant appearance in text: CYP2B6: Q172H; rs3745274

PubMed Link: 36320932

Variant Present in the following documents:

• GR2022-5754776.pdf

View BVdb publication page

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Pharmacogenomics in drug-induced cardiotoxicity: Current status and the future.

Frontiers In Cardiovascular Medicine

Li, Mo-Yun MY; Peng, Li-Ming LM; Chen, Xiao-Ping XP

Publication Date: 2022

Variant appearance in text: rs3745274

PubMed Link: 36312261

Variant Present in the following documents:

• Main text
• fcvm-09-966261.pdf
• Table_1.pdf

View BVdb publication page

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Comparison of genetic susceptibility to lung adenocarcinoma and squamous cell carcinoma in Japanese patients using a novel panel for cancer-related drug-metabolizing enzyme genes.

Scientific Reports

Ohnami, Sumiko S; Naruoka, Akane A; Isaka, Mitsuhiro M; Mizuguchi, Maki M; Nakatani, Sou S; Kamada, Fukumi F; Shimoda, Yuji Y; Sakai, Ai A; Ohshima, Keiichi K; Hatakeyama, Keiichi K; Maruyama, Kouji K; Ohde, Yasuhisa Y; Kenmotsu, Hirotsugu H; Takahashi, Toshiaki T; Akiyama, Yasuto Y; Nagashima, Takeshi T; Urakami, Kenichi K; Ohnami, Shumpei S; Yamaguchi, Ken K

Publication Date: 2022-10-26

Variant appearance in text: rs3745274

PubMed Link: 36289279

Variant Present in the following documents:

• Main text
• 41598_2022_Article_22914.pdf

View BVdb publication page

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Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.

Scientific Reports

Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA

Publication Date: 2022-10-14

Variant appearance in text: CYP2B6: Q172H

PubMed Link: 36241656

Variant Present in the following documents:

• 41598_2022_20939_MOESM13_ESM.xlsx, sheet 2
• 41598_2022_20939_MOESM6_ESM.xlsx, sheet 2
• 41598_2022_20939_MOESM7_ESM.xlsx, sheet 2
• 41598_2022_20939_MOESM5_ESM.xlsx, sheet 2
• 41598_2022_20939_MOESM12_ESM.xlsx, sheet 2
• 41598_2022_20939_MOESM8_ESM.xlsx, sheet 2
• 41598_2022_20939_MOESM9_ESM.xlsx, sheet 2

View BVdb publication page

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Association between gene polymorphisms in the cyclophosphamide metabolism pathway with complications after haploidentical hematopoietic stem cell transplantation.

Frontiers In Immunology

Muñiz, Paula P; Andrés-Zayas, Cristina C; Carbonell, Diego D; Chicano, María M; Bailén, Rebeca R; Oarbeascoa, Gillen G; Suárez-González, Julia J; Gómez Centurión, Ignacio I; Dorado, Nieves N; Gallardo, David D; Anguita, Javier J; Kwon, Mi M; Díez-Martín, Jose L JL; Martínez-Laperche, Carolina C; Buño, Ismael I

Publication Date: 2022

Variant appearance in text: rs3745274

PubMed Link: 36211438

Variant Present in the following documents:

• Table_1.xlsx, sheet 1

View BVdb publication page

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The genetic landscape of major drug metabolizing cytochrome P450 genes-an updated analysis of population-scale sequencing data.

The Pharmacogenomics Journal

Zhou, Yitian Y; Lauschke, Volker M VM

Publication Date: 2022-12

Variant appearance in text: CYP2B6: Q172H; rs3745274

PubMed Link: 36068297

Variant Present in the following documents:

• Main text
• 41397_2022_Article_288.pdf

View BVdb publication page

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CYP2C8*3 and *4 define CYP2C8 phenotype: An approach with the substrate cinitapride.

Clinical And Translational Science

Campodónico, Diana María DM; Zubiaur, Pablo P; Soria-Chacartegui, Paula P; Casajús, Ana A; Villapalos-García, Gonzalo G; Navares-Gómez, Marcos M; Gómez-Fernández, Antía A; Parra-Garcés, Raúl R; Mejía-Abril, Gina G; Román, Manuel M; Martín-Vílchez, Samuel S; Ochoa, Dolores D; Abad-Santos, Francisco F

Publication Date: 2022-11

Variant appearance in text: rs3745274

PubMed Link: 36065758

Variant Present in the following documents:

• Main text
• CTS-15-2613.pdf

View BVdb publication page

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Investigation of the genetic effect of 56 tobacco-smoking susceptibility genes on DNA methylation and RNA expression in human brain.

Frontiers In Psychiatry

Yang, Zhongli Z; Yang, Jiekun J; Mao, Ying Y; Li, Ming D MD

Publication Date: 2022

Variant appearance in text: CYP2B6: 516G>T; Q172H; rs3745274

PubMed Link: 36061282

Variant Present in the following documents:

• fpsyt-13-924062.pdf

View BVdb publication page

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The Effects of Cumulative Dose and Polymorphisms in CYP2B6 on the Mitotane Plasma Trough Concentrations in Chinese Patients With Advanced Adrenocortical Carcinoma.

Frontiers In Oncology

Liu, Xin X; Shang, Junmei J; Fu, Qiang Q; Lu, Lin L; Deng, Jianhua J; Tang, Yan Y; Li, Jiantao J; Mei, Dan D; Zhang, Bo B; Zhang, Shuyang S

Publication Date: 2022

Variant appearance in text: CYP2B6: Q172H; rs3745274

PubMed Link: 35847963

Variant Present in the following documents:

• fonc-12-919027.pdf

View BVdb publication page

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Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing.

Frontiers In Pharmacology

Silgado-Guzmán, Daniel Felipe DF; Angulo-Aguado, Mariana M; Morel, Adrien A; Niño-Orrego, María José MJ; Ruiz-Torres, Daniel-Armando DA; Contreras Bravo, Nora Constanza NC; Restrepo, Carlos Martin CM; Ortega-Recalde, Oscar O; Fonseca-Mendoza, Dora Janeth DJ

Publication Date: 2022

Variant appearance in text: CYP2B6: 516G>T; Gln172His; rs3745274

PubMed Link: 35846994

Variant Present in the following documents:

• Table1.xlsx, sheet 1

View BVdb publication page

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The Impact of Pharmacogenetics on Pharmacokinetics and Pharmacodynamics in Neonates and Infants: A Systematic Review.

Pharmacogenomics And Personalized Medicine

Yalçin, Nadir N; Flint, Robert B RB; van Schaik, Ron H N RHN; Simons, Sinno H P SHP; Allegaert, Karel K

Publication Date: 2022

Variant appearance in text: rs3745274

PubMed Link: 35795337

Variant Present in the following documents:

• Main text
• pgpm-15-675.pdf

View BVdb publication page

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Pharmacogenetics of Breast Cancer Treatments: A Sub-Saharan Africa Perspective.

Pharmacogenomics And Personalized Medicine

Nthontho, Keneuoe Cecilia KC; Ndlovu, Andrew Khulekani AK; Sharma, Kirthana K; Kasvosve, Ishmael I; Hertz, Daniel Louis DL; Paganotti, Giacomo Maria GM

Publication Date: 2022

Variant appearance in text: CYP2B6: Q172H; rs3745274

PubMed Link: 35761855

Variant Present in the following documents:

• Main text
• pgpm-15-613.pdf

View BVdb publication page

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Pharmacogenomic Profile of Amazonian Amerindians.

Journal Of Personalized Medicine

Rodrigues, Juliana Carla Gomes JCG; Fernandes, Marianne Rodrigues MR; Ribeiro-Dos-Santos, André Maurício AM; de Araújo, Gilderlanio Santana GS; de Souza, Sandro José SJ; Guerreiro, João Farias JF; Ribeiro-Dos-Santos, Ândrea Â; de Assumpção, Paulo Pimentel PP; Santos, Ney Pereira Carneiro Dos NPCD; Santos, Sidney S

Publication Date: 2022-06-10

Variant appearance in text: rs3745274

PubMed Link: 35743738

Variant Present in the following documents:

• Main text
• jpm-12-00952.pdf

View BVdb publication page

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Pharmacogenetics of Dolutegravir Plasma Exposure Among Southern Africans With Human Immunodeficiency Virus.

The Journal Of Infectious Diseases

Cindi, Zinhle Z; Kawuma, Aida N AN; Maartens, Gary G; Bradford, Yuki Y; Venter, Francois F; Sokhela, Simiso S; Chandiwana, Nomathemba N; Wasmann, Roeland E RE; Denti, Paolo P; Wiesner, Lubbe L; Ritchie, Marylyn D MD; Haas, David W DW; Sinxadi, Phumla P

Publication Date: 2022-11-01

Variant appearance in text: rs3745274

PubMed Link: 35512135

Variant Present in the following documents:

• EMS145648-supplement-Supplementary_file.pdf

View BVdb publication page

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Drug Repurposing in Cancer Therapy: Influence of Patient's Genetic Background in Breast Cancer Treatment.

International Journal Of Molecular Sciences

Rodrigues, Rafaela R; Duarte, Diana D; Vale, Nuno N

Publication Date: 2022-04-14

Variant appearance in text: rs3745274

PubMed Link: 35457144

Variant Present in the following documents:

• Main text
• ijms-23-04280.pdf

View BVdb publication page

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Pharmacogene Variants Associated with Liver Transplant in a Twelve-Year Clinical Follow-Up.

Pharmaceutics

Sendra, Luis L; Olivera, Gladys G GG; López-Andújar, Rafael R; Serrano, Cristina C; Rojas, Luis E LE; Montalvá, Eva María EM; Herrero, María José MJ; Aliño, Salvador F SF

Publication Date: 2022-02-03

Variant appearance in text: rs3745274

PubMed Link: 35214086

Variant Present in the following documents:

• pharmaceutics-14-00354.pdf

View BVdb publication page

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CYP2C19 plays a major role in the hepatic N-oxidation of cotinine.

Drug Metabolism And Disposition: The Biological Fate Of Chemicals

Perez-Paramo, Yadira X YX; Watson, Christy J W CJW; Chen, Gang G; Lazarus, Philip P

Publication Date: 2022-02-23

Variant appearance in text: rs3745274

PubMed Link: 35197312

Variant Present in the following documents:

• Main text
• dmd.121.000624.pdf

View BVdb publication page

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CYP2B6 allelic variants and non-genetic factors influence CYP2B6 enzyme function.

Scientific Reports

Mangó, Katalin K; Kiss, Ádám Ferenc ÁF; Fekete, Ferenc F; Erdős, Réka R; Monostory, Katalin K

Publication Date: 2022-02-22

Variant appearance in text: CYP2B6: 516G>T; Q172H; rs3745274

PubMed Link: 35194103

Variant Present in the following documents:

• 41598_2022_Article_7022.pdf

View BVdb publication page

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