JAK-STAT signaling in inflammatory breast cancer enables chemotherapy-resistant cell states.
Cancer Research
Stevens, Laura E LE; Peluffo, Guillermo G; Qiu, Xintao X; Temko, Daniel D; Fassl, Anne A; Li, Zheqi Z; Trinh, Anne A; Seehawer, Marco M; Jovanovic, Bojana B; Aleckovic, Masa M; Wilde, Callahan M CM; Geck, Renee C RC; Shu, Shaokun S; Kingston, Natalie L NL; Harper, Nicholas W NW; Almendro, Vanessa V; Pyke, Alanna L AL; Egri, Shawn B SB; Papanastasiou, Malvina M; Clement, Kendell K; Zhou, Ningxuan N; Walker, Sarah S; Salas, Jacqueline J; Park, So Yeon SY; Frank, David A DA; Meissner, Alexander A; Jaffe, Jacob D JD; Sicinski, Piotr P; Toker, Alex A; Michor, Franziska F; Long, Henry W HW; Overmoyer, Beth A BA; Polyak, Kornelia K
Publication Date: 2022-11-21
Variant appearance in text: CYP2B6: 823-197T>C; rs2279345
Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
The Effects of Cumulative Dose and Polymorphisms in CYP2B6 on the Mitotane Plasma Trough Concentrations in Chinese Patients With Advanced Adrenocortical Carcinoma.
Frontiers In Oncology
Liu, Xin X; Shang, Junmei J; Fu, Qiang Q; Lu, Lin L; Deng, Jianhua J; Tang, Yan Y; Li, Jiantao J; Mei, Dan D; Zhang, Bo B; Zhang, Shuyang S
Dexketoprofen Pharmacokinetics is not Significantly Altered by Genetic Polymorphism.
Frontiers In Pharmacology
Mejía-Abril, Gina G; Zubiaur, Pablo P; Navares-Gómez, Marcos M; Villapalos-García, Gonzalo G; Román, Manuel M; Ochoa, Dolores D; Abad-Santos, Francisco F
SLCO1B1 Phenotype and CYP3A5 Polymorphism Significantly Affect Atorvastatin Bioavailability.
Journal Of Personalized Medicine
Zubiaur, Pablo P; Benedicto, Maria Dolores MD; Villapalos-García, Gonzalo G; Navares-Gómez, Marcos M; Mejía-Abril, Gina G; Román, Manuel M; Martín-Vílchez, Samuel S; Ochoa, Dolores D; Abad-Santos, Francisco F
Pharmacogenomics of methadone: a narrative review of the literature.
Pharmacogenomics
Packiasabapathy, Senthil S; Aruldhas, Blessed W BW; Horn, Nicole N; Overholser, Brian R BR; Quinney, Sara K SK; Renschler, Janelle S JS; Sadhasivam, Senthilkumar S
Introducing the first whole genomes of nationals from the United Arab Emirates.
Scientific Reports
AlSafar, Habiba S HS; Al-Ali, Mariam M; Elbait, Gihan Daw GD; Al-Maini, Mustafa H MH; Ruta, Dymitr D; Peramo, Braulio B; Henschel, Andreas A; Tay, Guan K GK
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2B6 and Efavirenz-Containing Antiretroviral Therapy.
Clinical Pharmacology And Therapeutics
Desta, Zeruesenay Z; Gammal, Roseann S RS; Gong, Li L; Whirl-Carrillo, Michelle M; Gaur, Aditya H AH; Sukasem, Chonlaphat C; Hockings, Jennifer J; Myers, Alan A; Swart, Marelize M; Tyndale, Rachel F RF; Masimirembwa, Collen C; Iwuchukwu, Otito F OF; Chirwa, Sanika S; Lennox, Jeffrey J; Gaedigk, Andrea A; Klein, Teri E TE; Haas, David W DW
Polymorphisms in cytochrome P450 are associated with extensive efavirenz pharmacokinetics and CNS toxicities in an HIV cohort in Botswana.
The Pharmacogenomics Journal
Vujkovic, Marijana M; Bellamy, Scarlett L SL; Zuppa, Athena F AF; Gastonguay, Marc R MR; Moorthy, Ganesh S GS; Ratshaa, Bakgaki B; Han, Xiaoyan X; Steenhoff, Andrew P AP; Mosepele, Mosepele M; Strom, Brian L BL; Bisson, Gregory P GP; Aplenc, Richard R; Gross, Robert R
Genetic variants in CYP2B6 and CYP2A6 explain interindividual variation in efavirenz plasma concentrations of HIV-infected children with diverse ethnic origin.
Plos One
Soeria-Atmadja, Sandra S; Österberg, Emma E; Gustafsson, Lars L LL; Dahl, Marja-Liisa ML; Eriksen, Jaran J; Rubin, Johanna J; Navér, Lars L
Multiphenotype association study of patients randomized to initiate antiretroviral regimens in AIDS Clinical Trials Group protocol A5202.
Pharmacogenetics And Genomics
Verma, Anurag A; Bradford, Yuki Y; Verma, Shefali S SS; Pendergrass, Sarah A SA; Daar, Eric S ES; Venuto, Charles C; Morse, Gene D GD; Ritchie, Marylyn D MD; Haas, David W DW
Genome-Wide Pharmacogenomic Study on Methadone Maintenance Treatment Identifies SNP rs17180299 and Multiple Haplotypes on CYP2B6, SPON1, and GSG1L Associated with Plasma Concentrations of Methadone R- and S-enantiomers in Heroin-Dependent Patients.
Pharmacogenetics of plasma efavirenz exposure in HIV-infected adults and children in South Africa.
British Journal Of Clinical Pharmacology
Sinxadi, Phumla Z PZ; Leger, Paul D PD; McIlleron, Helen M HM; Smith, Peter J PJ; Dave, Joel A JA; Levitt, Naomi S NS; Maartens, Gary G; Haas, David W DW
Genetic variation in the CYP2B6 gene is related to circulating 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) concentrations: an observational population-based study.
Environmental Health : A Global Access Science Source
Penell, Johanna J; Lind, Lars L; Fall, Tove T; Syvänen, Anne-Christine AC; Axelsson, Tomas T; Lundmark, Per P; Morris, Andrew P AP; Lindgren, Cecilia C; Mahajan, Anubha A; Salihovic, Samira S; van Bavel, Bert B; Ingelsson, Erik E; Lind, P Monica PM
Multiple genetic variants predict steady-state nevirapine clearance in HIV-infected Cambodians.
Pharmacogenetics And Genomics
Bertrand, Julie J; Chou, Monidarin M; Richardson, Danielle M DM; Verstuyft, Céline C; Leger, Paul D PD; Mentré, France F; Taburet, Anne-Marie AM; Haas, David W DW; ,
Potential contribution of cytochrome P450 2B6 to hepatic 4-hydroxycyclophosphamide formation in vitro and in vivo.
Drug Metabolism And Disposition: The Biological Fate Of Chemicals
Raccor, Brianne S BS; Claessens, Adam J AJ; Dinh, Jean C JC; Park, Julie R JR; Hawkins, Douglas S DS; Thomas, Sushma S SS; Makar, Karen W KW; McCune, Jeannine S JS; Totah, Rheem A RA
Influence of CYP2B6 polymorphisms on the persistence of plasma nevirapine concentrations following a single intra-partum dose for the prevention of mother to child transmission in HIV-infected Thai women.
The Journal Of Antimicrobial Chemotherapy
Chantarangsu, Soranun S; Cressey, Tim R TR; Mahasirimongkol, Surakameth S; Capparelli, Edmund E; Tawon, Yardpiroon Y; Ngo-Giang-Huong, Nicole N; Jourdain, Gonzague G; Lallemant, Marc M; Chantratita, Wasun W