Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Therapeutic and Toxic Effects of Valproic Acid Metabolites.
Metabolites
Shnayder, Natalia A NA; Grechkina, Violetta V VV; Khasanova, Aiperi K AK; Bochanova, Elena N EN; Dontceva, Evgenia A EA; Petrova, Marina M MM; Asadullin, Azat R AR; Shipulin, German A GA; Altynbekov, Kuanysh S KS; Al-Zamil, Mustafa M; Nasyrova, Regina F RF
Immunogenomic analysis of human brain metastases reveals diverse immune landscapes across genetically distinct tumors.
Cell Reports. Medicine
Álvarez-Prado, Ángel F ÁF; Maas, Roeltje R RR; Soukup, Klara K; Klemm, Florian F; Kornete, Mara M; Krebs, Fanny S FS; Zoete, Vincent V; Berezowska, Sabina S; Brouland, Jean-Philippe JP; Hottinger, Andreas F AF; Daniel, Roy T RT; Hegi, Monika E ME; Joyce, Johanna A JA
Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Association between gene polymorphisms in the cyclophosphamide metabolism pathway with complications after haploidentical hematopoietic stem cell transplantation.
Frontiers In Immunology
Muñiz, Paula P; Andrés-Zayas, Cristina C; Carbonell, Diego D; Chicano, María M; Bailén, Rebeca R; Oarbeascoa, Gillen G; Suárez-González, Julia J; Gómez Centurión, Ignacio I; Dorado, Nieves N; Gallardo, David D; Anguita, Javier J; Kwon, Mi M; Díez-Martín, Jose L JL; Martínez-Laperche, Carolina C; Buño, Ismael I
CYP2C8*3 and *4 define CYP2C8 phenotype: An approach with the substrate cinitapride.
Clinical And Translational Science
Campodónico, Diana María DM; Zubiaur, Pablo P; Soria-Chacartegui, Paula P; Casajús, Ana A; Villapalos-García, Gonzalo G; Navares-Gómez, Marcos M; Gómez-Fernández, Antía A; Parra-Garcés, Raúl R; Mejía-Abril, Gina G; Román, Manuel M; Martín-Vílchez, Samuel S; Ochoa, Dolores D; Abad-Santos, Francisco F
Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing.
Frontiers In Pharmacology
Silgado-Guzmán, Daniel Felipe DF; Angulo-Aguado, Mariana M; Morel, Adrien A; Niño-Orrego, María José MJ; Ruiz-Torres, Daniel-Armando DA; Contreras Bravo, Nora Constanza NC; Restrepo, Carlos Martin CM; Ortega-Recalde, Oscar O; Fonseca-Mendoza, Dora Janeth DJ
Publication Date: 2022
Variant appearance in text: CYP2B6: 1459C>T; Arg487Cys; rs3211371
Genomic, transcriptomic, and metabolomic profiles of hiPSC-derived dopamine neurons from clinically discordant brothers with identical PRKN deletions.
Npj Parkinson'S Disease
Cukier, Holly N HN; Kim, Hyunjin H; Griswold, Anthony J AJ; Codreanu, Simona G SG; Prince, Lisa M LM; Sherrod, Stacy D SD; McLean, John A JA; Dykxhoorn, Derek M DM; Ess, Kevin C KC; Hedera, Peter P; Bowman, Aaron B AB; Neely, M Diana MD
Publication Date: 2022-06-29
Variant appearance in text: CYP2B6: R487C; rs3211371
Association between genetic polymorphisms in cytochrome P450 enzymes and survivals in women with breast cancer receiving adjuvant endocrine therapy: a systematic review and meta-analysis.
Expert Reviews In Molecular Medicine
Chan, Carmen Wing Han CWH; Li, Caixia C; Xiao, Eleven Jinnan EJ; Li, Minjie M; Phiri, Patrick Gladson McLeywick PGM; Yan, Tingting T; Chan, Judy Yuet Wa JYW
The correlation between the level of 3-hydroxypropyl mercapturic acid, CYP2B6 polymorphisms, and hematuria occurrences after cyclophosphamide administration and its bioanalytical methods: A systematic review.
Heliyon
Harahap, Yahdiana Y; Nurahman, Farhan F; Purwanto, Denni Joko DJ; Yanuar, Arry A
Effects of Cytochrome P450 and Transporter Polymorphisms on the Bioavailability and Safety of Dutasteride and Tamsulosin.
Frontiers In Pharmacology
Villapalos-García, Gonzalo G; Zubiaur, Pablo P; Navares-Gómez, Marcos M; Saiz-Rodríguez, Miriam M; Mejía-Abril, Gina G; Martín-Vílchez, Samuel S; Román, Manuel M; Ochoa, Dolores D; Abad-Santos, Francisco F
Variants in COMT, CYP3A5, CYP2B6, and ABCG2 Alter Quetiapine Pharmacokinetics.
Pharmaceutics
Zubiaur, Pablo P; Fernández-Campos, Paula P; Navares-Gómez, Marcos M; Soria-Chacartegui, Paula P; Villapalos-García, Gonzalo G; Román, Manuel M; Mejía-Abril, Gina G; Ochoa, Dolores D; Abad-Santos, Francisco F
Precision Medicine into Clinical Practice: A Web-Based Tool Enables Real-Time Pharmacogenetic Assessment of Tailored Treatments in Psychiatric Disorders.
Journal Of Personalized Medicine
Zampatti, Stefania S; Fabrizio, Carlo C; Ragazzo, Michele M; Campoli, Giulia G; Caputo, Valerio V; Strafella, Claudia C; Pellicano, Clelia C; Cascella, Raffaella R; Spalletta, Gianfranco G; Petrosini, Laura L; Caltagirone, Carlo C; Termine, Andrea A; Giardina, Emiliano E
Publication Date: 2021-08-27
Variant appearance in text: CYP2B6: 1459C>T; Arg487Cys; rs3211371
PriME-PGx: La Princesa University Hospital Multidisciplinary Initiative for the Implementation of Pharmacogenetics.
Journal Of Clinical Medicine
Zubiaur, Pablo P; Mejía-Abril, Gina G; Navares-Gómez, Marcos M; Villapalos-García, Gonzalo G; Soria-Chacartegui, Paula P; Saiz-Rodríguez, Miriam M; Ochoa, Dolores D; Abad-Santos, Francisco F
Frequency of Important CYP450 Enzyme Gene Polymorphisms in the Iranian Population in Comparison with Other Major Populations: A Comprehensive Review of the Human Data.
Journal Of Personalized Medicine
Neyshaburinezhad, Navid N; Ghasim, Hengameh H; Rouini, Mohammadreza M; Daali, Youssef Y; Ardakani, Yalda H YH
Individualized Drugs' Selection by Evaluation of Drug Properties, Pharmacogenomics and Clinical Parameters: Performance of a Bioinformatic Tool Compared to a Clinically Established Counselling Process.
Pharmacogenomics And Personalized Medicine
Borro, Marina M; Gentile, Giovanna G; Preissner, Sally H SH; Pomes, Leda Marina LM; Gohlke, Björn-Oliver BO; Del Casale, Antonio A; Eckert, Andreas A; Marchetti, Paolo P; Preissner, Saskia S; Preissner, Robert R; Simmaco, Maurizio M
Dexketoprofen Pharmacokinetics is not Significantly Altered by Genetic Polymorphism.
Frontiers In Pharmacology
Mejía-Abril, Gina G; Zubiaur, Pablo P; Navares-Gómez, Marcos M; Villapalos-García, Gonzalo G; Román, Manuel M; Ochoa, Dolores D; Abad-Santos, Francisco F
Pharmacogene Sequencing of a Gabonese Population with Severe Plasmodium falciparum Malaria Reveals Multiple Novel Variants with Putative Relevance for Antimalarial Treatment.
Antimicrobial Agents And Chemotherapy
Pernaute-Lau, Leyre L; Adegnika, Ayola Akim AA; Zhou, Yitian Y; Zinsou, Jeannot F JF; Gil, Jose Pedro JP; Krishna, Sanjeev S; Kremsner, Peter G PG; Lauschke, Volker M VM; Velavan, Thirumalaisamy P TP
Publication Date: 2021-06-17
Variant appearance in text: CYP2B6: R487C; rs3211371
Pharmacogenetic predictors of nevirapine pharmacokinetics in Ghanaian children living with HIV with or without TB coinfection.
Infection, Genetics And Evolution : Journal Of Molecular Epidemiology And Evolutionary Genetics In Infectious Diseases
Langaee, Taimour T; Al-Shaer, Mohammad H MH; Gong, Yan Y; Lima, Elizabeth E; Antwi, Sampson S; Enimil, Anthony A; Dompreh, Albert A; Yang, Hongmei H; Alghamdi, Wael A WA; Wiesner, Lubbe L; Peloquin, Charles A CA; Kwara, Awewura A
SLCO1B1 Phenotype and CYP3A5 Polymorphism Significantly Affect Atorvastatin Bioavailability.
Journal Of Personalized Medicine
Zubiaur, Pablo P; Benedicto, Maria Dolores MD; Villapalos-García, Gonzalo G; Navares-Gómez, Marcos M; Mejía-Abril, Gina G; Román, Manuel M; Martín-Vílchez, Samuel S; Ochoa, Dolores D; Abad-Santos, Francisco F
Drug-Drug Interactions and Pharmacogenomic Evaluation in Colorectal Cancer Patients: The New Drug-PIN® System Comprehensive Approach.
Pharmaceuticals (Basel, Switzerland)
Roberto, Michela M; Rossi, Alessandro A; Panebianco, Martina M; Pomes, Leda Marina LM; Arrivi, Giulia G; Ierinò, Debora D; Simmaco, Maurizio M; Marchetti, Paolo P; Mazzuca, Federica F
Publication Date: 2021-01-15
Variant appearance in text: CYP2B6: Arg487Cys; rs3211371