Publications:

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APOE alleles modulate associations of plasma metabolites with variants from multiple genes on chromosome 19q13.3.

Frontiers In Aging Neuroscience

Nazarian, Alireza A; Loiko, Elena E; Yassine, Hussein N HN; Finch, Caleb E CE; Kulminski, Alexander M AM

Publication Date: 2022

Variant appearance in text: rs519113

PubMed Link: 36389057

Variant Present in the following documents:

• Main text
• fnagi-14-1023493.pdf

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Haplotype architecture of the Alzheimer's risk in the APOE region via co-skewness.

Alzheimer'S & Dementia (Amsterdam, Netherlands)

Kulminski, Alexander M AM; Philipp, Ian I; Loika, Yury Y; He, Liang L; Culminskaya, Irina I

Publication Date: 2020

Variant appearance in text: rs519113

PubMed Link: 33204816

Variant Present in the following documents:

• Main text
• DAD2-12-e12129.pdf

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Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population.

Alzheimer'S & Dementia (Amsterdam, Netherlands)

Zhou, Xiaopu X; Chen, Yu Y; Ip, Fanny C F FCF; Lai, Nicole C H NCH; Li, Yolanda Y T YYT; Jiang, Yuanbing Y; Zhong, Huan H; Chen, Yuewen Y; Zhang, Yulin Y; Ma, Shuangshuang S; Lo, Ronnie M N RMN; Cheung, Kit K; Tong, Estella P S EPS; Ko, Ho H; Shoai, Maryam M; Mok, Kin Y KY; Hardy, John J; Mok, Vincent C T VCT; Kwok, Timothy C Y TCY; Fu, Amy K Y AKY; Ip, Nancy Y NY

Publication Date: 2020

Variant appearance in text: rs519113

PubMed Link: 32775599

Variant Present in the following documents:

• Main text
• DAD2-12-e12074-s001.pdf
• DAD2-12-e12074.pdf

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Association of the NCAN-TM6SF2-CILP2-PBX4-SUGP1-MAU2 SNPs and gene-gene and gene-environment interactions with serum lipid levels.

Aging

Deng, Guo-Xiong GX; Yin, Rui-Xing RX; Guan, Yao-Zong YZ; Liu, Chun-Xiao CX; Zheng, Peng-Fei PF; Wei, Bi-Liu BL; Wu, Jin-Zhen JZ; Miao, Liu L

Publication Date: 2020-06-22

Variant appearance in text: rs519113

PubMed Link: 32568739

Variant Present in the following documents:

• Main text
• aging-12-103361.pdf

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Genetic and regulatory architecture of Alzheimer's disease in the APOE region.

Alzheimer'S & Dementia (Amsterdam, Netherlands)

Kulminski, Alexander M AM; Shu, Leonardo L; Loika, Yury Y; He, Liang L; Nazarian, Alireza A; Arbeev, Konstantin K; Ukraintseva, Svetlana S; Yashin, Anatoliy A; Culminskaya, Irina I

Publication Date: 2020

Variant appearance in text: rs519113

PubMed Link: 32211503

Variant Present in the following documents:

• Main text
• DAD2-12-e12008.pdf
• DAD2-12-e12008-s007.xlsx, sheet 1

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DNA methylation QTL analysis identifies new regulators of human longevity.

Human Molecular Genetics

Szymczak, Silke S; Dose, Janina J; Torres, Guillermo G GG; Heinsen, Femke-Anouska FA; Venkatesh, Geetha G; Datlinger, Paul P; Nygaard, Marianne M; Mengel-From, Jonas J; Flachsbart, Friederike F; Klapper, Wolfram W; Christensen, Kaare K; Lieb, Wolfgang W; Schreiber, Stefan S; Häsler, Robert R; Bock, Christoph C; Franke, Andre A; Nebel, Almut A

Publication Date: 2020-05-08

Variant appearance in text: rs519113

PubMed Link: 32160291

Variant Present in the following documents:

• Main text
• ddaa033.pdf

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Non-coding variability at the APOE locus contributes to the Alzheimer's risk.

Nature Communications

Zhou, Xiaopu X; Chen, Yu Y; Mok, Kin Y KY; Kwok, Timothy C Y TCY; Mok, Vincent C T VCT; Guo, Qihao Q; Ip, Fanny C FC; Chen, Yuewen Y; Mullapudi, Nandita N; , ; Giusti-Rodríguez, Paola P; Sullivan, Patrick F PF; Hardy, John J; Fu, Amy K Y AKY; Li, Yun Y; Ip, Nancy Y NY

Publication Date: 2019-07-25

Variant appearance in text: rs519113

PubMed Link: 31346172

Variant Present in the following documents:

• Main text
• 41467_2019_Article_10945.pdf
• 41467_2019_10945_MOESM1_ESM.pdf

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The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.

Scientific Reports

Moon, Sanghoon S; Kim, Young Jin YJ; Han, Sohee S; Hwang, Mi Yeong MY; Shin, Dong Mun DM; Park, Min Young MY; Lu, Yontao Y; Yoon, Kyungheon K; Jang, Hye-Mi HM; Kim, Yun Kyoung YK; Park, Tae-Joon TJ; Song, Dae Sub DS; Park, Jae Kyung JK; Lee, Jong-Eun JE; Kim, Bong-Jo BJ

Publication Date: 2019-02-04

Variant appearance in text: rs519113

PubMed Link: 30718733

Variant Present in the following documents:

• 41598_2018_37832_MOESM1_ESM.pdf

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PRS-on-Spark (PRSoS): a novel, efficient and flexible approach for generating polygenic risk scores.

Bmc Bioinformatics

Chen, Lawrence M LM; Yao, Nelson N; Garg, Elika E; Zhu, Yuecai Y; Nguyen, Thao T T TTT; Pokhvisneva, Irina I; Hari Dass, Shantala A SA; Unternaehrer, Eva E; Gaudreau, Hélène H; Forest, Marie M; McEwen, Lisa M LM; MacIsaac, Julia L JL; Kobor, Michael S MS; Greenwood, Celia M T CMT; Silveira, Patricia P PP; Meaney, Michael J MJ; O'Donnell, Kieran J KJ

Publication Date: 2018-08-08

Variant appearance in text: rs519113

PubMed Link: 30089455

Variant Present in the following documents:

• Main text
• 12859_2018_Article_2289.pdf

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BCL3-PVRL2-TOMM40 SNPs, gene-gene and gene-environment interactions on dyslipidemia.

Scientific Reports

Miao, Liu L; Yin, Rui-Xing RX; Pan, Shang-Ling SL; Yang, Shuo S; Yang, De-Zhai DZ; Lin, Wei-Xiong WX

Publication Date: 2018-04-18

Variant appearance in text: rs519113

PubMed Link: 29670124

Variant Present in the following documents:

• Main text
• 41598_2018_Article_24432.pdf

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Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer's disease pathogenesis.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Zhou, Xiaopu X; Chen, Yu Y; Mok, Kin Y KY; Zhao, Qianhua Q; Chen, Keliang K; Chen, Yuewen Y; Hardy, John J; Li, Yun Y; Fu, Amy K Y AKY; Guo, Qihao Q; Ip, Nancy Y NY; ,

Publication Date: 2018-02-20

Variant appearance in text: rs519113

PubMed Link: 29432188

Variant Present in the following documents:

• pnas.1715554115.sapp.pdf

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Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals.

Biodata Mining

Holzinger, Emily R ER; Verma, Shefali S SS; Moore, Carrie B CB; Hall, Molly M; De, Rishika R; Gilbert-Diamond, Diane D; Lanktree, Matthew B MB; Pankratz, Nathan N; Amuzu, Antoinette A; Burt, Amber A; Dale, Caroline C; Dudek, Scott S; Furlong, Clement E CE; Gaunt, Tom R TR; Kim, Daniel Seung DS; Riess, Helene H; Sivapalaratnam, Suthesh S; Tragante, Vinicius V; van Iperen, Erik P A EPA; Brautbar, Ariel A; Carrell, David S DS; Crosslin, David R DR; Jarvik, Gail P GP; Kuivaniemi, Helena H; Kullo, Iftikhar J IJ; Larson, Eric B EB; Rasmussen-Torvik, Laura J LJ; Tromp, Gerard G; Baumert, Jens J; Cruickshanks, Karen J KJ; Farrall, Martin M; Hingorani, Aroon D AD; Hovingh, G K GK; Kleber, Marcus E ME; Klein, Barbara E BE; Klein, Ronald R; Koenig, Wolfgang W; Lange, Leslie A LA; Mӓrz, Winfried W; North, Kari E KE; Charlotte Onland-Moret, N N; Reiner, Alex P AP; Talmud, Philippa J PJ; van der Schouw, Yvonne T YT; Wilson, James G JG; Kivimaki, Mika M; Kumari, Meena M; Moore, Jason H JH; Drenos, Fotios F; Asselbergs, Folkert W FW; Keating, Brendan J BJ; Ritchie, Marylyn D MD

Publication Date: 2017

Variant appearance in text: rs519113

PubMed Link: 28770004

Variant Present in the following documents:

• Main text
• 13040_2017_Article_145.pdf

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The genetic overlap between mood disorders and cardiometabolic diseases: a systematic review of genome wide and candidate gene studies.

Translational Psychiatry

Amare, A T AT; Schubert, K O KO; Klingler-Hoffmann, M M; Cohen-Woods, S S; Baune, B T BT

Publication Date: 2017-01-24

Variant appearance in text: rs519113

PubMed Link: 28117839

Variant Present in the following documents:

• Main text
• tp2016261a.pdf

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Genetic variants in PVRL2-TOMM40-APOE region are associated with human longevity in a Han Chinese population.

Plos One

Lu, Fang F; Guan, Huaijin H; Gong, Bo B; Liu, Xiaoqi X; Zhu, Rongrong R; Wang, Yong Y; Qian, Jingjing J; Zhou, Tianqiu T; Lan, Xiaoyan X; Wang, Pu P; Lin, Ying Y; Ma, Shi S; Lin, He H; Zhu, Xiong X; Chen, Rong R; Zhu, Xianjun X; Shi, Yi Y; Yang, Zhenglin Z

Publication Date: 2014

Variant appearance in text: rs519113

PubMed Link: 24924924

Variant Present in the following documents:

• Main text

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Heritability and genomics of gene expression in peripheral blood.

Nature Genetics

Wright, Fred A FA; Sullivan, Patrick F PF; Brooks, Andrew I AI; Zou, Fei F; Sun, Wei W; Xia, Kai K; Madar, Vered V; Jansen, Rick R; Chung, Wonil W; Zhou, Yi-Hui YH; Abdellaoui, Abdel A; Batista, Sandra S; Butler, Casey C; Chen, Guanhua G; Chen, Ting-Huei TH; D'Ambrosio, David D; Gallins, Paul P; Ha, Min Jin MJ; Hottenga, Jouke Jan JJ; Huang, Shunping S; Kattenberg, Mathijs M; Kochar, Jaspreet J; Middeldorp, Christel M CM; Qu, Ani A; Shabalin, Andrey A; Tischfield, Jay J; Todd, Laura L; Tzeng, Jung-Ying JY; van Grootheest, Gerard G; Vink, Jacqueline M JM; Wang, Qi Q; Wang, Wei W; Wang, Weibo W; Willemsen, Gonneke G; Smit, Johannes H JH; de Geus, Eco J EJ; Yin, Zhaoyu Z; Penninx, Brenda W J H BW; Boomsma, Dorret I DI

Publication Date: 2014-05

Variant appearance in text: rs519113

PubMed Link: 24728292

Variant Present in the following documents:

• NIHMS576016-supplement-1.pdf

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Effect of genetic predisposition on blood lipid traits using cumulative risk assessment in the korean population.

Genomics & Informatics

Go, Min Jin MJ; Hwang, Joo-Yeon JY; Kim, Dong-Joon DJ; Lee, Hye-Ja HJ; Jang, Han Byul HB; Park, Kyung-Hee KH; Song, Jihyun J; Lee, Jong-Young JY

Publication Date: 2012-06

Variant appearance in text: rs519113

PubMed Link: 23105936

Variant Present in the following documents:

• Main text
• gni-10-99.pdf

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Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.

Molecular Psychiatry

Shyn, S I SI; Shi, J J; Kraft, J B JB; Potash, J B JB; Knowles, J A JA; Weissman, M M MM; Garriock, H A HA; Yokoyama, J S JS; McGrath, P J PJ; Peters, E J EJ; Scheftner, W A WA; Coryell, W W; Lawson, W B WB; Jancic, D D; Gejman, P V PV; Sanders, A R AR; Holmans, P P; Slager, S L SL; Levinson, D F DF; Hamilton, S P SP

Publication Date: 2011-02

Variant appearance in text: rs519113

PubMed Link: 20038947

Variant Present in the following documents:

• NIHMS142361-supplement-1.pdf

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