Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine.
Nature Genetics
Schlosser, Pascal P; Scherer, Nora N; Grundner-Culemann, Franziska F; Monteiro-Martins, Sara S; Haug, Stefan S; Steinbrenner, Inga I; Uluvar, Burulça B; Wuttke, Matthias M; Cheng, Yurong Y; Ekici, Arif B AB; Gyimesi, Gergely G; Karoly, Edward D ED; Kotsis, Fruzsina F; Mielke, Johanna J; Gomez, Maria F MF; Yu, Bing B; Grams, Morgan E ME; Coresh, Josef J; Boerwinkle, Eric E; Köttgen, Michael M; Kronenberg, Florian F; Meiselbach, Heike H; Mohney, Robert P RP; Akilesh, Shreeram S; , ; Schmidts, Miriam M; Hediger, Matthias A MA; Schultheiss, Ulla T UT; Eckardt, Kai-Uwe KU; Oefner, Peter J PJ; Sekula, Peggy P; Li, Yong Y; Köttgen, Anna A
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.
Nature
Pairo-Castineira, Erola E; Rawlik, Konrad K; Bretherick, Andrew D AD; Qi, Ting T; Wu, Yang Y; Nassiri, Isar I; McConkey, Glenn A GA; Zechner, Marie M; Klaric, Lucija L; Griffiths, Fiona F; Oosthuyzen, Wilna W; Kousathanas, Athanasios A; Richmond, Anne A; Millar, Jonathan J; Russell, Clark D CD; Malinauskas, Tomas T; Thwaites, Ryan R; Morrice, Kirstie K; Keating, Sean S; Maslove, David D; Nichol, Alistair A; Semple, Malcolm G MG; Knight, Julian J; Shankar-Hari, Manu M; Summers, Charlotte C; Hinds, Charles C; Horby, Peter P; Ling, Lowell L; McAuley, Danny D; Montgomery, Hugh H; Openshaw, Peter J M PJM; Begg, Colin C; Walsh, Timothy T; Tenesa, Albert A; Flores, Carlos C; Riancho, José A JA; Rojas-Martinez, Augusto A; Lapunzina, Pablo P; , ; , ; , ; , ; Yang, Jian J; Ponting, Chris P CP; Wilson, James F JF; Vitart, Veronique V; Abedalthagafi, Malak M; Luchessi, Andre D AD; Parra, Esteban J EJ; Cruz, Raquel R; Carracedo, Angel A; Fawkes, Angie A; Murphy, Lee L; Rowan, Kathy K; Pereira, Alexandre C AC; Law, Andy A; Fairfax, Benjamin B; Hendry, Sara Clohisey SC; Baillie, J Kenneth JK
Association of Inherited Genetic Factors With Drug-Induced Hepatic Damage Among Children With Acute Lymphoblastic Leukemia.
Jama Network Open
Yang, Wenjian W; Karol, Seth E SE; Hoshitsuki, Keito K; Lee, Shawn S; Larsen, Eric C EC; Winick, Naomi N; Carroll, William L WL; Loh, Mignon L ML; Raetz, Elizabeth A EA; Hunger, Stephen P SP; Winter, Stuart S SS; Dunsmore, Kimberly P KP; Devidas, Meenakshi M; Relling, Mary V MV; Yang, Jun J JJ
The contribution of common and rare genetic variants to variation in metabolic traits in 288,137 East Asians.
Nature Communications
Kim, Young Jin YJ; Moon, Sanghoon S; Hwang, Mi Yeong MY; Han, Sohee S; Jang, Hye-Mi HM; Kong, Jinhwa J; Shin, Dong Mun DM; Yoon, Kyungheon K; Kim, Sung Min SM; Lee, Jong-Eun JE; Mahajan, Anubha A; Park, Hyun-Young HY; McCarthy, Mark I MI; Cho, Yoon Shin YS; Kim, Bong-Jo BJ
Extensive Study of Breast Milk and Infant Growth: Protocol of the Cambridge Baby Growth and Breastfeeding Study (CBGS-BF).
Nutrients
Olga, Laurentya L; Petry, Clive J CJ; van Diepen, Janna A JA; Prentice, Philippa M PM; Hughes, Ieuan A IA; Vervoort, Jacques J; Boekhorst, Jos J; Chichlowski, Maciej M; Gross, Gabriele G; Dunger, David B DB; Ong, Ken K KK
Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes.
Nature Genetics
Robertson, Catherine C CC; Inshaw, Jamie R J JRJ; Onengut-Gumuscu, Suna S; Chen, Wei-Min WM; Santa Cruz, David Flores DF; Yang, Hanzhi H; Cutler, Antony J AJ; Crouch, Daniel J M DJM; Farber, Emily E; Bridges, S Louis SL; Edberg, Jeffrey C JC; Kimberly, Robert P RP; Buckner, Jane H JH; Deloukas, Panos P; Divers, Jasmin J; Dabelea, Dana D; Lawrence, Jean M JM; Marcovina, Santica S; Shah, Amy S AS; Greenbaum, Carla J CJ; Atkinson, Mark A MA; Gregersen, Peter K PK; Oksenberg, Jorge R JR; Pociot, Flemming F; Rewers, Marian J MJ; Steck, Andrea K AK; Dunger, David B DB; , ; Wicker, Linda S LS; Concannon, Patrick P; Todd, John A JA; Rich, Stephen S SS
Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes.
Nature Genetics
Robertson, Catherine C CC; Inshaw, Jamie R J JRJ; Onengut-Gumuscu, Suna S; Chen, Wei-Min WM; Santa Cruz, David Flores DF; Yang, Hanzhi H; Cutler, Antony J AJ; Crouch, Daniel J M DJM; Farber, Emily E; Bridges, S Louis SL; Edberg, Jeffrey C JC; Kimberly, Robert P RP; Buckner, Jane H JH; Deloukas, Panos P; Divers, Jasmin J; Dabelea, Dana D; Lawrence, Jean M JM; Marcovina, Santica S; Shah, Amy S AS; Greenbaum, Carla J CJ; Atkinson, Mark A MA; Gregersen, Peter K PK; Oksenberg, Jorge R JR; Pociot, Flemming F; Rewers, Marian J MJ; Steck, Andrea K AK; Dunger, David B DB; , ; Wicker, Linda S LS; Concannon, Patrick P; Todd, John A JA; Rich, Stephen S SS
A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis.
Communications Biology
Bell, Steven S; Rigas, Andreas S AS; Magnusson, Magnus K MK; Ferkingstad, Egil E; Allara, Elias E; Bjornsdottir, Gyda G; Ramond, Anna A; Sørensen, Erik E; Halldorsson, Gisli H GH; Paul, Dirk S DS; Burgdorf, Kristoffer S KS; Eggertsson, Hannes P HP; Howson, Joanna M M JMM; Thørner, Lise W LW; Kristmundsdottir, Snaedis S; Astle, William J WJ; Erikstrup, Christian C; Sigurdsson, Jon K JK; Vuckovic, Dragana D; Dinh, Khoa M KM; Tragante, Vinicius V; Surendran, Praveen P; Pedersen, Ole B OB; Vidarsson, Brynjar B; Jiang, Tao T; Paarup, Helene M HM; Onundarson, Pall T PT; Akbari, Parsa P; Nielsen, Kaspar R KR; Lund, Sigrun H SH; Juliusson, Kristinn K; Magnusson, Magnus I MI; Frigge, Michael L ML; Oddsson, Asmundur A; Olafsson, Isleifur I; Kaptoge, Stephen S; Hjalgrim, Henrik H; Runarsson, Gudmundur G; Wood, Angela M AM; Jonsdottir, Ingileif I; Hansen, Thomas F TF; Sigurdardottir, Olof O; Stefansson, Hreinn H; Rye, David D; , ; Peters, James E JE; Westergaard, David D; Holm, Hilma H; Soranzo, Nicole N; Banasik, Karina K; Thorleifsson, Gudmar G; Ouwehand, Willem H WH; Thorsteinsdottir, Unnur U; Roberts, David J DJ; Sulem, Patrick P; Butterworth, Adam S AS; Gudbjartsson, Daniel F DF; Danesh, John J; Brunak, Søren S; Di Angelantonio, Emanuele E; Ullum, Henrik H; Stefansson, Kari K
Publication Date: 2021-02-03
Variant appearance in text: FUT2: -2-40C>T; rs516246
FUT2-ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses.
Nature Communications
Ahluwalia, Tarunveer S TS; Eliasen, Anders U AU; Sevelsted, Astrid A; Pedersen, Casper-Emil T CT; Stokholm, Jakob J; Chawes, Bo B; Bork-Jensen, Jette J; Grarup, Niels N; Pedersen, Oluf O; Hansen, Torben T; Linneberg, Allan A; Sharma, Amitabh A; Weiss, Scott T ST; Evans, Michael D MD; Jackson, Daniel J DJ; Morin, Andreanne A; Krogfelt, Karen A KA; Schjørring, Susanne S; Mortensen, Preben B PB; Hougaard, David M DM; Bybjerg-Grauholm, Jonas J; Bækvad-Hansen, Marie M; Mors, Ole O; Nordentoft, Merete M; Børglum, Anders D AD; Werge, Thomas T; Agerbo, Esben E; Gern, James E JE; Lemanske, Robert F RF; Ober, Carole C; Pedersen, Anders G AG; Bisgaard, Hans H; Bønnelykke, Klaus K
Clinical and genetic correlates of islet-autoimmune signatures in juvenile-onset type 1 diabetes.
Diabetologia
Claessens, Laura A LA; Wesselius, Joris J; van Lummel, Menno M; Laban, Sandra S; Mulder, Flip F; Mul, Dick D; Nikolic, Tanja T; Aanstoot, Henk-Jan HJ; Koeleman, Bobby P C BPC; Roep, Bart O BO
The effect of liver enzymes on adiposity: a Mendelian randomization study.
Scientific Reports
Liu, Junxi J; Au Yeung, Shiu Lun SL; Kwok, Man Ki MK; Leung, June Yue Yan JYY; Lin, Shi Lin SL; Hui, Lai Ling LL; Leung, Gabriel Matthew GM; Schooling, C Mary CM
Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines.
Scientific Reports
Skowron, Margaretha A MA; Petzsch, Patrick P; Hardt, Karin K; Wagner, Nicholas N; Beier, Manfred M; Stepanow, Stefanie S; Drechsler, Matthias M; Rieder, Harald H; Köhrer, Karl K; Niegisch, Günter G; Hoffmann, Michèle J MJ; Schulz, Wolfgang A WA
Genome-Wide Association Study Identifies Loci for Liver Enzyme Concentrations in Mexican Americans: The GUARDIAN Consortium.
Obesity (Silver Spring, Md.)
Young, Kendra A KA; Palmer, Nicholette D ND; Fingerlin, Tasha E TE; Langefeld, Carl D CD; Norris, Jill M JM; Wang, Nan N; Xiang, Anny H AH; Guo, Xiuqing X; Williams, Adrienne H AH; Chen, Yii-Der I YI; Taylor, Kent D KD; Rotter, Jerome I JI; Raffel, Leslie J LJ; Goodarzi, Mark O MO; Watanabe, Richard M RM; Wagenknecht, Lynne E LE
Liver Function and Risk of Type 2 Diabetes: Bidirectional Mendelian Randomization Study.
Diabetes
De Silva, N Maneka G NMG; Borges, Maria Carolina MC; Hingorani, Aroon D AD; Engmann, Jorgen J; Shah, Tina T; Zhang, Xiaoshuai X; Luan, Jian'an J; Langenberg, Claudia C; Wong, Andrew A; Kuh, Diana D; Chambers, John C JC; Zhang, Weihua W; Jarvelin, Marjo-Ritta MR; Sebert, Sylvain S; Auvinen, Juha J; , ; Gaunt, Tom R TR; Lawlor, Deborah A DA
FUT2 genotype and secretory status are not associated with fecal microbial composition and inferred function in healthy subjects.
Gut Microbes
Turpin, Williams W; Bedrani, Larbi L; Espin-Garcia, Osvaldo O; Xu, Wei W; Silverberg, Mark S MS; Smith, Michelle I MI; Guttman, David S DS; Griffiths, Anne A; Moayyedi, Paul P; Panaccione, Remo R; Huynh, Hien H; Steinhart, Hillary H; Aumais, Guy G; Shestopaloff, Konstantin K; Dieleman, Levinus A LA; Turner, Dan D; Paterson, Andrew D AD; Croitoru, Kenneth K
Fine-mapping inflammatory bowel disease loci to single-variant resolution.
Nature
Huang, Hailiang H; Fang, Ming M; Jostins, Luke L; Umićević Mirkov, Maša M; Boucher, Gabrielle G; Anderson, Carl A CA; Andersen, Vibeke V; Cleynen, Isabelle I; Cortes, Adrian A; Crins, François F; D'Amato, Mauro M; Deffontaine, Valérie V; Dmitrieva, Julia J; Docampo, Elisa E; Elansary, Mahmoud M; Farh, Kyle Kai-How KK; Franke, Andre A; Gori, Ann-Stephan AS; Goyette, Philippe P; Halfvarson, Jonas J; Haritunians, Talin T; Knight, Jo J; Lawrance, Ian C IC; Lees, Charlie W CW; Louis, Edouard E; Mariman, Rob R; Meuwissen, Theo T; Mni, Myriam M; Momozawa, Yukihide Y; Parkes, Miles M; Spain, Sarah L SL; Théâtre, Emilie E; Trynka, Gosia G; Satsangi, Jack J; van Sommeren, Suzanne S; Vermeire, Severine S; Xavier, Ramnik J RJ; , ; Weersma, Rinse K RK; Duerr, Richard H RH; Mathew, Christopher G CG; Rioux, John D JD; McGovern, Dermot P B DPB; Cho, Judy H JH; Georges, Michel M; Daly, Mark J MJ; Barrett, Jeffrey C JC
Genetic Characterization and Influence on Inflammatory Bowel Disease Expression in a Diverse Hispanic South Florida Cohort.
Clinical And Translational Gastroenterology
Damas, Oriana M OM; Gomez, Lissette L; Quintero, Maria A MA; Rampersaud, Evadnie E; Slifer, Susan S; Beecham, Gary W GW; Kerman, David H DH; Deshpande, Amar R AR; Sussman, Daniel A DA; Abreu, Maria T MT; McCauley, Jacob L JL
Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease.
Gut
Imhann, Floris F; Vich Vila, Arnau A; Bonder, Marc Jan MJ; Fu, Jingyuan J; Gevers, Dirk D; Visschedijk, Marijn C MC; Spekhorst, Lieke M LM; Alberts, Rudi R; Franke, Lude L; van Dullemen, Hendrik M HM; Ter Steege, Rinze W F RWF; Huttenhower, Curtis C; Dijkstra, Gerard G; Xavier, Ramnik J RJ; Festen, Eleonora A M EAM; Wijmenga, Cisca C; Zhernakova, Alexandra A; Weersma, Rinse K RK
Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD.
Plos Genetics
Sun, Wei W; Kechris, Katerina K; Jacobson, Sean S; Drummond, M Bradley MB; Hawkins, Gregory A GA; Yang, Jenny J; Chen, Ting-Huei TH; Quibrera, Pedro Miguel PM; Anderson, Wayne W; Barr, R Graham RG; Basta, Patricia V PV; Bleecker, Eugene R ER; Beaty, Terri T; Casaburi, Richard R; Castaldi, Peter P; Cho, Michael H MH; Comellas, Alejandro A; Crapo, James D JD; Criner, Gerard G; Demeo, Dawn D; Christenson, Stephanie A SA; Couper, David J DJ; Curtis, Jeffrey L JL; Doerschuk, Claire M CM; Freeman, Christine M CM; Gouskova, Natalia A NA; Han, MeiLan K MK; Hanania, Nicola A NA; Hansel, Nadia N NN; Hersh, Craig P CP; Hoffman, Eric A EA; Kaner, Robert J RJ; Kanner, Richard E RE; Kleerup, Eric C EC; Lutz, Sharon S; Martinez, Fernando J FJ; Meyers, Deborah A DA; Peters, Stephen P SP; Regan, Elizabeth A EA; Rennard, Stephen I SI; Scholand, Mary Beth MB; Silverman, Edwin K EK; Woodruff, Prescott G PG; O'Neal, Wanda K WK; Bowler, Russell P RP; , ; ,
Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease.
Human Molecular Genetics
Orlando, Giulia G; Law, Philip J PJ; Palin, Kimmo K; Tuupanen, Sari S; Gylfe, Alexandra A; Hänninen, Ulrika A UA; Cajuso, Tatiana T; Tanskanen, Tomas T; Kondelin, Johanna J; Kaasinen, Eevi E; Sarin, Antti-Pekka AP; Kaprio, Jaakko J; Eriksson, Johan G JG; Rissanen, Harri H; Knekt, Paul P; Pukkala, Eero E; Jousilahti, Pekka P; Salomaa, Veikko V; Ripatti, Samuli S; Palotie, Aarno A; Järvinen, Heikki H; Renkonen-Sinisalo, Laura L; Lepistö, Anna A; Böhm, Jan J; Mecklin, Jukka-Pekka JP; Al-Tassan, Nada A NA; Palles, Claire C; Martin, Lynn L; Barclay, Ella E; Tenesa, Albert A; Farrington, Susan S; Timofeeva, Maria N MN; Meyer, Brian F BF; Wakil, Salma M SM; Campbell, Harry H; Smith, Christopher G CG; Idziaszczyk, Shelley S; Maughan, Timothy S TS; Kaplan, Richard R; Kerr, Rachel R; Kerr, David D; Buchanan, Daniel D DD; Win, Aung Ko AK; Hopper, John J; Jenkins, Mark M; Lindor, Noralane M NM; Newcomb, Polly A PA; Gallinger, Steve S; Conti, David D; Schumacher, Fred F; Casey, Graham G; Taipale, Jussi J; Cheadle, Jeremy P JP; Dunlop, Malcolm G MG; Tomlinson, Ian P IP; Aaltonen, Lauri A LA; Houlston, Richard S RS
Bruse, Shannon S; Moreau, Michael M; Bromberg, Yana Y; Jang, Jun-Ho JH; Wang, Nan N; Ha, Hongseok H; Picchi, Maria M; Lin, Yong Y; Langley, Raymond J RJ; Qualls, Clifford C; Klensney-Tait, Julia J; Zabner, Joseph J; Leng, Shuguang S; Mao, Jenny J; Belinsky, Steven A SA; Xing, Jinchuan J; Nyunoya, Toru T
Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial.
Frontiers In Public Health
Keene, Keith L KL; Chen, Wei-Min WM; Chen, Fang F; Williams, Stephen R SR; Elkhatib, Stacey D SD; Hsu, Fang-Chi FC; Mychaleckyj, Josyf C JC; Doheny, Kimberly F KF; Pugh, Elizabeth W EW; Ling, Hua H; Laurie, Cathy C CC; Gogarten, Stephanie M SM; Madden, Ebony B EB; Worrall, Bradford B BB; Sale, Michele M MM
Reprograming of gut microbiome energy metabolism by the FUT2 Crohn's disease risk polymorphism.
The Isme Journal
Tong, Maomeng M; McHardy, Ian I; Ruegger, Paul P; Goudarzi, Maryam M; Kashyap, Purna C PC; Haritunians, Talin T; Li, Xiaoxiao X; Graeber, Thomas G TG; Schwager, Emma E; Huttenhower, Curtis C; Fornace, Albert J AJ; Sonnenburg, Justin L JL; McGovern, Dermot P B DP; Borneman, James J; Braun, Jonathan J
Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links.
Plos Genetics
Rueedi, Rico R; Ledda, Mirko M; Nicholls, Andrew W AW; Salek, Reza M RM; Marques-Vidal, Pedro P; Morya, Edgard E; Sameshima, Koichi K; Montoliu, Ivan I; Da Silva, Laeticia L; Collino, Sebastiano S; Martin, François-Pierre FP; Rezzi, Serge S; Steinbeck, Christoph C; Waterworth, Dawn M DM; Waeber, Gérard G; Vollenweider, Peter P; Beckmann, Jacques S JS; Le Coutre, Johannes J; Mooser, Vincent V; Bergmann, Sven S; Genick, Ulrich K UK; Kutalik, Zoltán Z
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Nature
Jostins, Luke L; Ripke, Stephan S; Weersma, Rinse K RK; Duerr, Richard H RH; McGovern, Dermot P DP; Hui, Ken Y KY; Lee, James C JC; Schumm, L Philip LP; Sharma, Yashoda Y; Anderson, Carl A CA; Essers, Jonah J; Mitrovic, Mitja M; Ning, Kaida K; Cleynen, Isabelle I; Theatre, Emilie E; Spain, Sarah L SL; Raychaudhuri, Soumya S; Goyette, Philippe P; Wei, Zhi Z; Abraham, Clara C; Achkar, Jean-Paul JP; Ahmad, Tariq T; Amininejad, Leila L; Ananthakrishnan, Ashwin N AN; Andersen, Vibeke V; Andrews, Jane M JM; Baidoo, Leonard L; Balschun, Tobias T; Bampton, Peter A PA; Bitton, Alain A; Boucher, Gabrielle G; Brand, Stephan S; Büning, Carsten C; Cohain, Ariella A; Cichon, Sven S; D'Amato, Mauro M; De Jong, Dirk D; Devaney, Kathy L KL; Dubinsky, Marla M; Edwards, Cathryn C; Ellinghaus, David D; Ferguson, Lynnette R LR; Franchimont, Denis D; Fransen, Karin K; Gearry, Richard R; Georges, Michel M; Gieger, Christian C; Glas, Jürgen J; Haritunians, Talin T; Hart, Ailsa A; Hawkey, Chris C; Hedl, Matija M; Hu, Xinli X; Karlsen, Tom H TH; Kupcinskas, Limas L; Kugathasan, Subra S; Latiano, Anna A; Laukens, Debby D; Lawrance, Ian C IC; Lees, Charlie W CW; Louis, Edouard E; Mahy, Gillian G; Mansfield, John J; Morgan, Angharad R AR; Mowat, Craig C; Newman, William W; Palmieri, Orazio O; Ponsioen, Cyriel Y CY; Potocnik, Uros U; Prescott, Natalie J NJ; Regueiro, Miguel M; Rotter, Jerome I JI; Russell, Richard K RK; Sanderson, Jeremy D JD; Sans, Miquel M; Satsangi, Jack J; Schreiber, Stefan S; Simms, Lisa A LA; Sventoraityte, Jurgita J; Targan, Stephan R SR; Taylor, Kent D KD; Tremelling, Mark M; Verspaget, Hein W HW; De Vos, Martine M; Wijmenga, Cisca C; Wilson, David C DC; Winkelmann, Juliane J; Xavier, Ramnik J RJ; Zeissig, Sebastian S; Zhang, Bin B; Zhang, Clarence K CK; Zhao, Hongyu H; , ; Silverberg, Mark S MS; Annese, Vito V; Hakonarson, Hakon H; Brant, Steven R SR; Radford-Smith, Graham G; Mathew, Christopher G CG; Rioux, John D JD; Schadt, Eric E EE; Daly, Mark J MJ; Franke, Andre A; Parkes, Miles M; Vermeire, Severine S; Barrett, Jeffrey C JC; Cho, Judy H JH
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
Nature Genetics
Chambers, John C JC; Zhang, Weihua W; Sehmi, Joban J; Li, Xinzhong X; Wass, Mark N MN; Van der Harst, Pim P; Holm, Hilma H; Sanna, Serena S; Kavousi, Maryam M; Baumeister, Sebastian E SE; Coin, Lachlan J LJ; Deng, Guohong G; Gieger, Christian C; Heard-Costa, Nancy L NL; Hottenga, Jouke-Jan JJ; Kühnel, Brigitte B; Kumar, Vinod V; Lagou, Vasiliki V; Liang, Liming L; Luan, Jian'an J; Vidal, Pedro Marques PM; Mateo Leach, Irene I; O'Reilly, Paul F PF; Peden, John F JF; Rahmioglu, Nilufer N; Soininen, Pasi P; Speliotes, Elizabeth K EK; Yuan, Xin X; Thorleifsson, Gudmar G; Alizadeh, Behrooz Z BZ; Atwood, Larry D LD; Borecki, Ingrid B IB; Brown, Morris J MJ; Charoen, Pimphen P; Cucca, Francesco F; Das, Debashish D; de Geus, Eco J C EJ; Dixon, Anna L AL; Döring, Angela A; Ehret, Georg G; Eyjolfsson, Gudmundur I GI; Farrall, Martin M; Forouhi, Nita G NG; Friedrich, Nele N; Goessling, Wolfram W; Gudbjartsson, Daniel F DF; Harris, Tamara B TB; Hartikainen, Anna-Liisa AL; Heath, Simon S; Hirschfield, Gideon M GM; Hofman, Albert A; Homuth, Georg G; Hyppönen, Elina E; Janssen, Harry L A HL; Johnson, Toby T; Kangas, Antti J AJ; Kema, Ido P IP; Kühn, Jens P JP; Lai, Sandra S; Lathrop, Mark M; Lerch, Markus M MM; Li, Yun Y; Liang, T Jake TJ; Lin, Jing-Ping JP; Loos, Ruth J F RJ; Martin, Nicholas G NG; Moffatt, Miriam F MF; Montgomery, Grant W GW; Munroe, Patricia B PB; Musunuru, Kiran K; Nakamura, Yusuke Y; O'Donnell, Christopher J CJ; Olafsson, Isleifur I; Penninx, Brenda W BW; Pouta, Anneli A; Prins, Bram P BP; Prokopenko, Inga I; Puls, Ralf R; Ruokonen, Aimo A; Savolainen, Markku J MJ; Schlessinger, David D; Schouten, Jeoffrey N L JN; Seedorf, Udo U; Sen-Chowdhry, Srijita S; Siminovitch, Katherine A KA; Smit, Johannes H JH; Spector, Timothy D TD; Tan, Wenting W; Teslovich, Tanya M TM; Tukiainen, Taru T; Uitterlinden, Andre G AG; Van der Klauw, Melanie M MM; Vasan, Ramachandran S RS; Wallace, Chris C; Wallaschofski, Henri H; Wichmann, H-Erich HE; Willemsen, Gonneke G; Würtz, Peter P; Xu, Chun C; Yerges-Armstrong, Laura M LM; , ; , ; , ; , ; , ; , ; , ; Abecasis, Goncalo R GR; Ahmadi, Kourosh R KR; Boomsma, Dorret I DI; Caulfield, Mark M; Cookson, William O WO; van Duijn, Cornelia M CM; Froguel, Philippe P; Matsuda, Koichi K; McCarthy, Mark I MI; Meisinger, Christa C; Mooser, Vincent V; Pietiläinen, Kirsi H KH; Schumann, Gunter G; Snieder, Harold H; Sternberg, Michael J E MJ; Stolk, Ronald P RP; Thomas, Howard C HC; Thorsteinsdottir, Unnur U; Uda, Manuela M; Waeber, Gérard G; Wareham, Nicholas J NJ; Waterworth, Dawn M DM; Watkins, Hugh H; Whitfield, John B JB; Witteman, Jacqueline C M JC; Wolffenbuttel, Bruce H R BH; Fox, Caroline S CS; Ala-Korpela, Mika M; Stefansson, Kari K; Vollenweider, Peter P; Völzke, Henry H; Schadt, Eric E EE; Scott, James J; Järvelin, Marjo-Riitta MR; Elliott, Paul P; Kooner, Jaspal S JS