FGF21 c.36A>G ;(p.G12=)

Variant ID: 19-49259529-A-G

NM_019113.2(FGF21):c.36A>G;(p.G12=)

This variant was identified in 85 publications

View GRCh38 version.




Publications:


Association of NAFLD with FGF21 Polygenic Hazard Score, and Its Interaction with Protein Intake Level in Korean Adults.

Nutrients
Lee, Hae Jin HJ; Shon, Jinyoung J; Park, Yoon Jung YJ
Publication Date: 2023-05-19

Variant appearance in text: rs838133
PubMed Link: 37242268
Variant Present in the following documents:
  • Main text
  • nutrients-15-02385.pdf
View BVdb publication page



Non-pharmacological management options for MAFLD: a practical guide.

Therapeutic Advances In Endocrinology And Metabolism
Stefano, José Tadeu JT; Duarte, Sebastião Mauro Bezerra SMB; Ribeiro Leite Altikes, Renato Gama RG; Oliveira, Claudia P CP
Publication Date: 2023

Variant appearance in text: rs838133
PubMed Link: 36968655
Variant Present in the following documents:
  • Main text
  • 10.1177_20420188231160394.pdf
View BVdb publication page



Evaluation of polygenic risk score for risk prediction of gastric cancer.

World Journal Of Gastrointestinal Oncology
Wang, Xiao-Yu XY; Wang, Li-Li LL; Xu, Lin L; Liang, Shu-Zhen SZ; Yu, Meng-Chao MC; Zhang, Qiu-Yue QY; Dong, Quan-Jiang QJ
Publication Date: 2023-02-15

Variant appearance in text: rs838133
PubMed Link: 36908320
Variant Present in the following documents:
  • WJGO-15-276.pdf
View BVdb publication page



Sleep Duration, Midday Napping, and Serum Homocysteine Levels: A Gene-Environment Interaction Study.

Nutrients
Mo, Tingting T; Wang, Yufei Y; Gao, Hui H; Li, Wending W; Zhou, Lue L; Yuan, Yu Y; Zhang, Xiaomin X; He, Meian M; Guo, Huan H; Long, Pinpin P; Wu, Tangchun T
Publication Date: 2023-01-01

Variant appearance in text: rs838133
PubMed Link: 36615867
Variant Present in the following documents:
  • nutrients-15-00210.pdf
View BVdb publication page



Effects of homocysteine on nonalcoholic fatty liver related disease: A mendelian randomization study.

Frontiers In Molecular Biosciences
Chen, Pengcheng P; Yang, Ze Z; Guo, Lingyun L; Huang, Yingfei Y; Li, Jingjia J; Chen, Xin X
Publication Date: 2022

Variant appearance in text: rs838133
PubMed Link: 36561351
Variant Present in the following documents:
  • Main text
  • fmolb-09-1083855.pdf
View BVdb publication page



Inferring causal effects of homocysteine and B-vitamin concentrations on bone mineral density and fractures: Mendelian randomization analyses.

Frontiers In Endocrinology
Fu, Liwan L; Wang, Yuquan Y; Hu, Yue-Qing YQ
Publication Date: 2022

Variant appearance in text: rs838133
PubMed Link: 36518252
Variant Present in the following documents:
  • Main text
  • fendo-13-1037546.pdf
View BVdb publication page



Causal effects of B vitamins and homocysteine on obesity and musculoskeletal diseases: A Mendelian randomization study.

Frontiers In Nutrition
Fu, Liwan L; Wang, Yuquan Y; Hu, Yue-Qing YQ
Publication Date: 2022

Variant appearance in text: rs838133
PubMed Link: 36505230
Variant Present in the following documents:
  • Main text
  • fnut-09-1048122.pdf
View BVdb publication page



Polymorphisms, diet and nutrigenomics.

Journal Of Preventive Medicine And Hygiene
Kiani, Aysha Karim AK; Bonetti, Gabriele G; Donato, Kevin K; Kaftalli, Jurgen J; Herbst, Karen L KL; Stuppia, Liborio L; Fioretti, Francesco F; Nodari, Savina S; Perrone, Marco M; Chiurazzi, Pietro P; Bellinato, Francesco F; Gisondi, Paolo P; Bertelli, Matteo M
Publication Date: 2022-06

Variant appearance in text: rs838133
PubMed Link: 36479483
Variant Present in the following documents:
  • Main text
  • jpmh-2022-02-e125.pdf
View BVdb publication page



Genetics in non-alcoholic fatty liver disease: The role of risk alleles through the lens of immune response.

Clinical And Molecular Hepatology
Sookoian, Silvia S; Pirola, Carlos J CJ
Publication Date: 2022-12-05

Variant appearance in text: rs838133
PubMed Link: 36472053
Variant Present in the following documents:
  • Main text
  • cmh-2022-0318.pdf
View BVdb publication page



Establishment and characterization of a new mantle cell lymphoma cell line with a NOTCH2 mutation, Arbo.

Ejhaem
Safa, Firas F; Rasmussen, Terri T; Lobelle-Rich, Patricia P; Collier, Stephanie S; Milligan, Nicholas N; Schmeig, John J; Schmid, Janet J; Wiewiorowski, Carol C; Totaro, Denise D; Brown, Theresa C TC; Satyavarapu, Ishwarya I; Badoo, Melody M; Ungerleider, Nathan N; Flemington, Erik K EK; Safah, Hana H; Saba, Nakhle S NS
Publication Date: 2022-11

Variant appearance in text: N/A
PubMed Link: 36467812
Variant Present in the following documents:
View BVdb publication page



The role of FGF21 and its analogs on liver associated diseases.

Frontiers In Medicine
Falamarzi, Kimia K; Malekpour, Mahdi M; Tafti, Mobin Fallah MF; Azarpira, Negar N; Behboodi, Mehrdad M; Zarei, Mohammad M
Publication Date: 2022

Variant appearance in text: rs838133
PubMed Link: 36457562
Variant Present in the following documents:
  • Main text
  • fmed-09-967375.pdf
View BVdb publication page



Hyperhomocysteinemia and intracranial aneurysm: A mendelian randomization study.

Frontiers In Neurology
Ma, Chencheng C; Zhang, Weiwei W; Mao, Lei L; Zhang, Guangjian G; Shen, Yuqi Y; Chang, Hanxiao H; Xu, Xiupeng X; Li, Zheng Z; Lu, Hua H
Publication Date: 2022

Variant appearance in text: rs838133
PubMed Link: 36247759
Variant Present in the following documents:
  • Main text
  • fneur-13-948989.pdf
View BVdb publication page



Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.

Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Publication Date: 2022-10-14

Variant appearance in text: N/A
PubMed Link: 36241656
Variant Present in the following documents:
View BVdb publication page



A genomic deletion encompassing CRYBB2-CRYBB2P1 is responsible for autosomal recessive congenital cataracts.

Human Genome Variation
Irum, Bushra B; Kabir, Firoz F; Shoshany, Nadav N; Khan, Shahid Y SY; Rauf, Bushra B; Naeem, Muhammad Asif MA; Qaiser, Tanveer A TA; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Publication Date: 2022-09-08

Variant appearance in text: N/A
PubMed Link: 36075891
Variant Present in the following documents:
View BVdb publication page



Genome-wide association study for circulating FGF21 in patients with alcohol use disorder: Molecular links between the SNHG16 locus and catecholamine metabolism.

Molecular Metabolism
Ho, Ming-Fen MF; Zhang, Cheng C; Moon, Irene I; Wei, Lixuan L; Coombes, Brandon B; Biernacka, Joanna J; Skime, Michelle M; Choi, Doo-Sup DS; Frye, Mark M; Schmidt, Kristen K; Gliske, Kate K; Braughton, Jacqueline J; Ngo, Quyen Q; Skillon, Cedric C; Seppala, Marvin M; Oesterle, Tyler T; Karpyak, Victor V; Li, Hu H; Weinshilboum, Richard R
Publication Date: 2022-09

Variant appearance in text: rs838133
PubMed Link: 35752286
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Personalized medicine in nonalcoholic fatty liver disease.

Clinical And Molecular Hepatology
Pirola, Carlos J CJ; Sookoian, Silvia S
Publication Date: 2022-10

Variant appearance in text: rs838133
PubMed Link: 35748062
Variant Present in the following documents:
  • Main text
  • cmh-2022-0175.pdf
View BVdb publication page



Empowering consumers to PREVENT diet-related diseases through OMICS sciences (PREVENTOMICS): protocol for a parallel double-blinded randomised intervention trial to investigate biomarker-based nutrition plans for weight loss.

Bmj Open
Aldubayan, Mona Adnan MA; Pigsborg, Kristina K; Gormsen, Sophia M O SMO; Serra, Francisca F; Palou, Mariona M; Mena, Pedro P; Wetzels, Mart M; Calleja, Alberto A; Caimari, Antoni A; Del Bas, Josep J; Gutierrez, Biotza B; Magkos, Faidon F; Hjorth, Mads Fiil MF
Publication Date: 2022-03-29

Variant appearance in text: rs838133
PubMed Link: 35351696
Variant Present in the following documents:
  • Main text
  • bmjopen-2021-051285.pdf
  • bmjopen-2021-051285.draft_revisions.pdf
View BVdb publication page



Artificial sweeteners and cancer risk: Results from the NutriNet-Santé population-based cohort study.

Plos Medicine
Debras, Charlotte C; Chazelas, Eloi E; Srour, Bernard B; Druesne-Pecollo, Nathalie N; Esseddik, Younes Y; Szabo de Edelenyi, Fabien F; Agaësse, Cédric C; De Sa, Alexandre A; Lutchia, Rebecca R; Gigandet, Stéphane S; Huybrechts, Inge I; Julia, Chantal C; Kesse-Guyot, Emmanuelle E; Allès, Benjamin B; Andreeva, Valentina A VA; Galan, Pilar P; Hercberg, Serge S; Deschasaux-Tanguy, Mélanie M; Touvier, Mathilde M
Publication Date: 2022-03

Variant appearance in text: rs838133
PubMed Link: 35324894
Variant Present in the following documents:
  • Main text
  • pmed.1003950.pdf
View BVdb publication page



Fibroblast Growth Factor 21 Facilitates the Homeostatic Control of Feeding Behavior.

Journal Of Clinical Medicine
Wu, Chih-Ting CT; Chaffin, Aki T AT; Ryan, Karen K KK
Publication Date: 2022-01-24

Variant appearance in text: rs838133
PubMed Link: 35160033
Variant Present in the following documents:
  • Main text
  • jcm-11-00580.pdf
View BVdb publication page



Fibroblast Growth Factor 21 Facilitates the Homeostatic Control of Feeding Behavior.

Journal Of Clinical Medicine
Wu, Chih-Ting CT; Chaffin, Aki T AT; Ryan, Karen K KK
Publication Date: 2022-01-24

Variant appearance in text: rs838133
PubMed Link: 35160033
Variant Present in the following documents:
  • Main text
  • jcm-11-00580.pdf
View BVdb publication page



The influence of host genetics on liver microbiome composition in patients with NAFLD.

Ebiomedicine
Pirola, Carlos Jose CJ; Salatino, Adrian A; Quintanilla, Maria Florencia MF; Castaño, Gustavo Osvaldo GO; Garaycoechea, Martin M; Sookoian, Silvia S
Publication Date: 2022-01-26

Variant appearance in text: rs838133
PubMed Link: 35092912
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



The influence of host genetics on liver microbiome composition in patients with NAFLD.

Ebiomedicine
Pirola, Carlos Jose CJ; Salatino, Adrian A; Quintanilla, Maria Florencia MF; Castaño, Gustavo Osvaldo GO; Garaycoechea, Martin M; Sookoian, Silvia S
Publication Date: 2022-02

Variant appearance in text: rs838133
PubMed Link: 35092912
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Single Nucleotide Polymorphisms in Close Proximity to the Fibroblast Growth Factor 21 (FGF21) Gene Found to Be Associated with Sugar Intake in a Swedish Population.

Nutrients
Janzi, Suzanne S; González-Padilla, Esther E; Najafi, Kevin K; Ramne, Stina S; Ahlqvist, Emma E; Borné, Yan Y; Sonestedt, Emily E
Publication Date: 2021-11-05

Variant appearance in text: rs838133
PubMed Link: 34836209
Variant Present in the following documents:
  • Main text
View BVdb publication page



Does FGF21 Mediate the Potential Decrease in Sweet Food Intake and Preference Following Bariatric Surgery?

Nutrients
Nielsen, Mette S MS; Ritz, Christian C; Chenchar, Anne A; Bredie, Wender L P WLP; Gillum, Matthew P MP; Sjödin, Anders A
Publication Date: 2021-10-28

Variant appearance in text: rs838133
PubMed Link: 34836096
Variant Present in the following documents:
  • Main text
  • nutrients-13-03840.pdf
View BVdb publication page



The Impact of Homocysteine on the Risk of Hormone-Related Cancers: A Mendelian Randomization Study.

Frontiers In Nutrition
He, Qian Q; Yang, Ze Z; Sun, Yandi Y; Qu, Zihao Z; Jia, Xueyao X; Li, Jingjia J; Lin, Yindan Y; Luo, Yan Y
Publication Date: 2021

Variant appearance in text: rs838133
PubMed Link: 34504857
Variant Present in the following documents:
  • Main text
View BVdb publication page



The Interaction of Single Nucleotide Polymorphisms on Fibroblast Growth Factor 19 Superfamily Genes Is Associated With Alcohol Dependence-Related Aggression.

Frontiers In Genetics
Xu, Jinzhong J; Wu, Fenzan F; Wang, Fan F; Yang, Fan F; Liu, Meng M; Lou, Mengbei M; Wu, Linman L; Li, Hui H; Lin, Wenhui W; Fan, Yunchao Y; Chen, Li L; Liu, Yanlong Y; Xu, Haiyun H; He, Jue J
Publication Date: 2021

Variant appearance in text: rs838133
PubMed Link: 34490035
Variant Present in the following documents:
  • Main text
  • fgene-12-695835.pdf
View BVdb publication page



Mistranslation Drives Alterations in Protein Levels and the Effects of a Synonymous Variant at the Fibroblast Growth Factor 21 Locus.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
Bayoumi, Ali A; Elsayed, Asmaa A; Han, Shuanglin S; Petta, Salvatore S; Adams, Leon A LA; Aller, Rocio R; Khan, Anis A; García-Monzón, Carmelo C; Arias-Loste, María Teresa MT; Miele, Luca L; Latchoumanin, Olivier O; Alenizi, Shafi S; Gallego-Durán, Rocio R; Fischer, Janett J; Berg, Thomas T; Craxì, Antonio A; Metwally, Mayada M; Qiao, Liang L; Liddle, Christopher C; Yki-Järvinen, Hannele H; Bugianesi, Elisabetta E; Romero-Gomez, Manuel M; George, Jacob J; Eslam, Mohammed M
Publication Date: 2021-06

Variant appearance in text: rs838133
PubMed Link: 34141520
Variant Present in the following documents:
  • Main text
View BVdb publication page



Appraising the Causal Association of Plasma Homocysteine Levels With Atrial Fibrillation Risk: A Two-Sample Mendelian Randomization Study.

Frontiers In Genetics
Chen, Songzan S; Yang, Fangkun F; Xu, Tian T; Wang, Yao Y; Zhang, Kaijie K; Fu, Guosheng G; Zhang, Wenbin W
Publication Date: 2021

Variant appearance in text: rs838133
PubMed Link: 34122499
Variant Present in the following documents:
  • Main text
View BVdb publication page



Dietary Patterns and Their Associations With the FTO and FGF21 Gene Variants Among Emirati Adults.

Frontiers In Nutrition
Naja, Farah F; Itani, Leila L; Hammoudeh, Sarah S; Manzoor, Shaista S; Abbas, Nada N; Radwan, Hadia H; Saber-Ayad, Maha M
Publication Date: 2021

Variant appearance in text: rs838133
PubMed Link: 34095191
Variant Present in the following documents:
  • Main text
  • fnut-08-668901.pdf
View BVdb publication page



Case Report: A Variant Non-ketotic Hyperglycinemia With GLRX5 Mutations: Manifestation of Deficiency of Activities of the Respiratory Chain Enzymes.

Frontiers In Genetics
Feng, Wei-Xing WX; Zhuo, Xiu-Wei XW; Liu, Zhi-Mei ZM; Li, Jiu-Wei JW; Zhang, Wei-Hua WH; Wu, Yun Y; Han, Tong-Li TL; Fang, Fang F
Publication Date: 2021

Variant appearance in text: FGF21: 36A>G; rs838133
PubMed Link: 34054912
Variant Present in the following documents:
  • Table_2.xlsx, sheet 1
View BVdb publication page



Genetic Evidence Supporting Fibroblast Growth Factor 21 Signalling as a Pharmacological Target for Cardiometabolic Outcomes and Alzheimer's Disease.

Nutrients
Larsson, Susanna C SC; Gill, Dipender D
Publication Date: 2021-04-29

Variant appearance in text: rs838133
PubMed Link: 33946944
Variant Present in the following documents:
  • Main text
View BVdb publication page



Homocysteine, B vitamins, and cardiovascular disease: a Mendelian randomization study.

Bmc Medicine
Yuan, Shuai S; Mason, Amy M AM; Carter, Paul P; Burgess, Stephen S; Larsson, Susanna C SC
Publication Date: 2021-04-23

Variant appearance in text: rs838133
PubMed Link: 33888102
Variant Present in the following documents:
  • Main text
View BVdb publication page



A Mendelian Randomization Study of Plasma Homocysteine Levels and Cerebrovascular and Neurodegenerative Diseases.

Frontiers In Genetics
Liu, Weishi W; Zhang, Luyang L; Li, Shen S; Liu, Chen C; Tong, Ying Y; Fang, Hui H; Zhang, Rui R; Song, Bo B; Xia, Zongping Z; Xu, Yuming Y
Publication Date: 2021

Variant appearance in text: rs838133
PubMed Link: 33868384
Variant Present in the following documents:
  • Main text
View BVdb publication page



The Effect of FGF21 and Its Genetic Variants on Food and Drug Cravings, Adipokines and Metabolic Traits.

Biomedicines
Epperlein, Sarah S; Gebhardt, Claudia C; Rohde, Kerstin K; Chakaroun, Rima R; Patt, Marie M; Schamarek, Imke I; Kralisch, Susan S; Heiker, John T JT; Scholz, Markus M; Stumvoll, Michael M; Kovacs, Peter P; Breitfeld, Jana J; Tönjes, Anke A
Publication Date: 2021-03-29

Variant appearance in text: rs838133
PubMed Link: 33805553
Variant Present in the following documents:
  • Main text
  • biomedicines-09-00345.pdf
View BVdb publication page



Causal Effects of Homocysteine, Folate, and Cobalamin on Kidney Function: A Mendelian Randomization Study.

Nutrients
Park, Sehoon S; Lee, Soojin S; Kim, Yaerim Y; Cho, Semin S; Kim, Kwangsoo K; Kim, Yong Chul YC; Han, Seung Seok SS; Lee, Hajeong H; Lee, Jung Pyo JP; Joo, Kwon Wook KW; Lim, Chun Soo CS; Kim, Yon Su YS; Kim, Dong Ki DK
Publication Date: 2021-03-11

Variant appearance in text: rs838133
PubMed Link: 33799553
Variant Present in the following documents:
  • Main text
View BVdb publication page



Disseminated Talaromyces marneffei Infection in a Non-HIV Infant With a Homozygous Private Variant of RELB.

Frontiers In Cellular And Infection Microbiology
Ding, Xiaofang X; Huang, Han H; Zhong, Lili L; Chen, Min M; Peng, Fang F; Zhang, Bing B; Cui, Xinyu X; Yang, Xiu-An XA
Publication Date: 2021

Variant appearance in text: N/A
PubMed Link: 33791233
Variant Present in the following documents:
View BVdb publication page



Whole Genome Interpretation for a Family of Five.

Frontiers In Genetics
Corpas, Manuel M; Megy, Karyn K; Mistry, Vanisha V; Metastasio, Antonio A; Lehmann, Edmund E
Publication Date: 2021

Variant appearance in text: rs838133
PubMed Link: 33763108
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetics of 35 blood and urine biomarkers in the UK Biobank.

Nature Genetics
Sinnott-Armstrong, Nasa N; Tanigawa, Yosuke Y; Amar, David D; Mars, Nina N; Benner, Christian C; Aguirre, Matthew M; Venkataraman, Guhan Ram GR; Wainberg, Michael M; Ollila, Hanna M HM; Kiiskinen, Tuomo T; Havulinna, Aki S AS; Pirruccello, James P JP; Qian, Junyang J; Shcherbina, Anna A; , ; Rodriguez, Fatima F; Assimes, Themistocles L TL; Agarwala, Vineeta V; Tibshirani, Robert R; Hastie, Trevor T; Ripatti, Samuli S; Pritchard, Jonathan K JK; Daly, Mark J MJ; Rivas, Manuel A MA
Publication Date: 2021-02

Variant appearance in text: FGF21: 36A>G; rs838133
PubMed Link: 33462484
Variant Present in the following documents:
  • NIHMS1651539-supplement-2.xlsx, sheet 21
View BVdb publication page



FGF19 and FGF21 for the Treatment of NASH-Two Sides of the Same Coin? Differential and Overlapping Effects of FGF19 and FGF21 From Mice to Human.

Frontiers In Endocrinology
Henriksson, Emma E; Andersen, Birgitte B
Publication Date: 2020

Variant appearance in text: rs838133
PubMed Link: 33414764
Variant Present in the following documents:
  • Main text
View BVdb publication page



FGF21: An Emerging Therapeutic Target for Non-Alcoholic Steatohepatitis and Related Metabolic Diseases.

Frontiers In Endocrinology
Tillman, Erik J EJ; Rolph, Tim T
Publication Date: 2020

Variant appearance in text: rs838133
PubMed Link: 33381084
Variant Present in the following documents:
  • Main text
  • fendo-11-601290.pdf
View BVdb publication page



AKR-001, an Fc-FGF21 Analog, Showed Sustained Pharmacodynamic Effects on Insulin Sensitivity and Lipid Metabolism in Type 2 Diabetes Patients.

Cell Reports. Medicine
Kaufman, Allegra A; Abuqayyas, Lubna L; Denney, William S WS; Tillman, Erik J EJ; Rolph, Tim T
Publication Date: 2020-07-21

Variant appearance in text: rs838133
PubMed Link: 33205064
Variant Present in the following documents:
  • Main text
View BVdb publication page



An integrative machine learning approach to discovering multi-level molecular mechanisms of obesity using data from monozygotic twin pairs.

Royal Society Open Science
Kibble, Milla M; Khan, Suleiman A SA; Ammad-Ud-Din, Muhammad M; Bollepalli, Sailalitha S; Palviainen, Teemu T; Kaprio, Jaakko J; Pietiläinen, Kirsi H KH; Ollikainen, Miina M
Publication Date: 2020-10

Variant appearance in text: rs838133
PubMed Link: 33204460
Variant Present in the following documents:
  • Main text
View BVdb publication page