The survival rate of laryngeal squamous cell carcinoma: impact of IL1RAP rs4624606, IL1RL1 rs1041973, IL-6 rs1800795, BLK rs13277113, and TIMP3 rs9621532 single nucleotide polymorphisms.
Discover. Oncology
Pasvenskaite, Agne A; Liutkeviciene, Rasa R; Gedvilaite, Greta G; Vilkeviciute, Alvita A; Liutkevicius, Vykintas V; Uloza, Virgilijus V
Inflammatory and infectious upper respiratory diseases associate with 41 genomic loci and type 2 inflammation.
Nature Communications
Saarentaus, Elmo C EC; Karjalainen, Juha J; Rämö, Joel T JT; Kiiskinen, Tuomo T; Havulinna, Aki S AS; Mehtonen, Juha J; Hautakangas, Heidi H; Ruotsalainen, Sanni S; Tamlander, Max M; Mars, Nina N; , ; Toppila-Salmi, Sanna S; Pirinen, Matti M; Kurki, Mitja M; Ripatti, Samuli S; Daly, Mark M; Palotie, Tuula T; Mäkitie, Antti A; Palotie, Aarno A
Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Deep resequencing identifies candidate functional genes in leprosy GWAS loci.
Plos Neglected Tropical Diseases
Fava, Vinicius M VM; Dallmann-Sauer, Monica M; Orlova, Marianna M; Correa-Macedo, Wilian W; Van Thuc, Nguyen N; Thai, Vu Hong VH; Alcaïs, Alexandre A; Abel, Laurent L; Cobat, Aurélie A; Schurr, Erwin E
Publication Date: 2021-12
Variant appearance in text: IL1RL1: A78E; rs1041973
Deep resequencing identifies candidate functional genes in leprosy GWAS loci.
Plos Neglected Tropical Diseases
Fava, Vinicius M VM; Dallmann-Sauer, Monica M; Orlova, Marianna M; Correa-Macedo, Wilian W; Van Thuc, Nguyen N; Thai, Vu Hong VH; Alcaïs, Alexandre A; Abel, Laurent L; Cobat, Aurélie A; Schurr, Erwin E
Publication Date: 2021-12-08
Variant appearance in text: IL1RL1: A78E; rs1041973
Integrated genetic and metabolic landscapes predict vulnerabilities of temozolomide resistant glioblastoma cells.
Npj Systems Biology And Applications
Immanuel, Selva Rupa Christinal SRC; Ghanate, Avinash D AD; Parmar, Dharmeshkumar S DS; Yadav, Ritu R; Uthup, Riya R; Panchagnula, Venkateswarlu V; Raghunathan, Anu A
Publication Date: 2021-01-08
Variant appearance in text: IL1RL1: A78E; rs1041973
Interaction between MyD88, TIRAP and IL1RL1 against Helicobacter pylori infection.
Scientific Reports
Fulgione, Andrea A; Papaianni, Marina M; Cuomo, Paola P; Paris, Debora D; Romano, Marco M; Tuccillo, Concetta C; Palomba, Letizia L; Medaglia, Chiara C; De Seta, Massimiliano M; Esposito, Nicolino N; Motta, Andrea A; Iannelli, Antonio A; Iannelli, Domenico D; Capparelli, Rosanna R
Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium.
Jci Insight
Portelli, Michael A MA; Dijk, F Nicole FN; Ketelaar, Maria E ME; Shrine, Nick N; Hankinson, Jenny J; Bhaker, Sangita S; Grotenboer, Néomi S NS; Obeidat, Ma'en M; Henry, Amanda P AP; Billington, Charlotte K CK; Shaw, Dominick D; Johnson, Simon R SR; Pogson, Zara Ek ZE; Fogarty, Andrew A; McKeever, Tricia M TM; Nickle, David C DC; Bossé, Yohan Y; van den Berge, Maarten M; Faiz, Alen A; Brouwer, Sharon S; Vonk, Judith M JM; de Vos, Paul P; Brandsma, Corry-Anke CA; Vermeulen, Cornelis J CJ; Singapuri, Amisha A; Heaney, Liam G LG; Mansur, Adel H AH; Chaudhuri, Rekha R; Thomson, Neil C NC; Holloway, John W JW; Lockett, Gabrielle A GA; Howarth, Peter H PH; Niven, Robert R; Simpson, Angela A; Blakey, John D JD; Tobin, Martin D MD; Postma, Dirkje S DS; Hall, Ian P IP; Wain, Louise V LV; Nawijn, Martijn C MC; Brightling, Christopher E CE; Koppelman, Gerard H GH; Sayers, Ian I
Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines.
Scientific Reports
Skowron, Margaretha A MA; Petzsch, Patrick P; Hardt, Karin K; Wagner, Nicholas N; Beier, Manfred M; Stepanow, Stefanie S; Drechsler, Matthias M; Rieder, Harald H; Köhrer, Karl K; Niegisch, Günter G; Hoffmann, Michèle J MJ; Schulz, Wolfgang A WA
Publication Date: 2019-10-09
Variant appearance in text: IL1RL1: A78E; rs1041973
A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.
Scientific Reports
Stringer, Brett W BW; Day, Bryan W BW; D'Souza, Rochelle C J RCJ; Jamieson, Paul R PR; Ensbey, Kathleen S KS; Bruce, Zara C ZC; Lim, Yi Chieh YC; Goasdoué, Kate K; Offenhäuser, Carolin C; Akgül, Seçkin S; Allan, Suzanne S; Robertson, Thomas T; Lucas, Peter P; Tollesson, Gert G; Campbell, Scott S; Winter, Craig C; Do, Hongdo H; Dobrovic, Alexander A; Inglis, Po-Ling PL; Jeffree, Rosalind L RL; Johns, Terrance G TG; Boyd, Andrew W AW
Publication Date: 2019-03-20
Variant appearance in text: IL1RL1: A78E; rs1041973
Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases.
Cell Death & Disease
Grassi, Ludovica L; Alfonsi, Romina R; Francescangeli, Federica F; Signore, Michele M; De Angelis, Maria Laura ML; Addario, Antonio A; Costantini, Manuela M; Flex, Elisabetta E; Ciolfi, Andrea A; Pizzi, Simone S; Bruselles, Alessandro A; Pallocca, Matteo M; Simone, Giuseppe G; Haoui, Mustapha M; Falchi, Mario M; Milella, Michele M; Sentinelli, Steno S; Di Matteo, Paola P; Stellacci, Emilia E; Gallucci, Michele M; Muto, Giovanni G; Tartaglia, Marco M; De Maria, Ruggero R; Bonci, Désirée D
A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma.
Plos Genetics
Smith, Dirk D; Helgason, Hannes H; Sulem, Patrick P; Bjornsdottir, Unnur Steina US; Lim, Ai Ching AC; Sveinbjornsson, Gardar G; Hasegawa, Haruki H; Brown, Michael M; Ketchem, Randal R RR; Gavala, Monica M; Garrett, Logan L; Jonasdottir, Adalbjorg A; Jonasdottir, Aslaug A; Sigurdsson, Asgeir A; Magnusson, Olafur T OT; Eyjolfsson, Gudmundur I GI; Olafsson, Isleifur I; Onundarson, Pall Torfi PT; Sigurdardottir, Olof O; Gislason, David D; Gislason, Thorarinn T; Ludviksson, Bjorn Runar BR; Ludviksdottir, Dora D; Boezen, H Marike HM; Heinzmann, Andrea A; Krueger, Marcus M; Porsbjerg, Celeste C; Ahluwalia, Tarunveer S TS; Waage, Johannes J; Backer, Vibeke V; Deichmann, Klaus A KA; Koppelman, Gerard H GH; Bønnelykke, Klaus K; Bisgaard, Hans H; Masson, Gisli G; Thorsteinsdottir, Unnur U; Gudbjartsson, Daniel F DF; Johnston, James A JA; Jonsdottir, Ingileif I; Stefansson, Kari K
Publication Date: 2017-03
Variant appearance in text: ST2: Ala78Glu; rs1041973
The role of ST2 and ST2 genetic variants in schistosomiasis.
The Journal Of Allergy And Clinical Immunology
Long, Xin X; Daya, Michelle M; Zhao, Jianping J; Rafaels, Nicholas N; Liang, Huifang H; Potee, Joseph J; Campbell, Monica M; Zhang, Bixiang B; Araujo, Maria Ilma MI; Oliveira, Ricardo R RR; Mathias, Rasika A RA; Gao, Li L; Ruczinski, Ingo I; Georas, Steve N SN; Vercelli, Donata D; Beaty, Terri H TH; Barnes, Kathleen C KC; Chen, Xiaoping X; Chen, Qian Q
IL1RL1 asthma risk variants regulate airway type 2 inflammation.
Jci Insight
Gordon, Erin D ED; Palandra, Joe J; Wesolowska-Andersen, Agata A; Ringel, Lando L; Rios, Cydney L CL; Lachowicz-Scroggins, Marrah E ME; Sharp, Louis Z LZ; Everman, Jamie L JL; MacLeod, Hannah J HJ; Lee, Jae W JW; Mason, Robert J RJ; Matthay, Michael A MA; Sheldon, Richard T RT; Peters, Michael C MC; Nocka, Karl H KH; Fahy, John V JV; Seibold, Max A MA
Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells.
Stem Cell Reports
Garate, Zita Z; Quintana-Bustamante, Oscar O; Crane, Ana M AM; Olivier, Emmanuel E; Poirot, Laurent L; Galetto, Roman R; Kosinski, Penelope P; Hill, Collin C; Kung, Charles C; Agirre, Xabi X; Orman, Israel I; Cerrato, Laura L; Alberquilla, Omaira O; Rodriguez-Fornes, Fatima F; Fusaki, Noemi N; Garcia-Sanchez, Felix F; Maia, Tabita M TM; Ribeiro, Maria L ML; Sevilla, Julian J; Prosper, Felipe F; Jin, Shengfang S; Mountford, Joanne J; Guenechea, Guillermo G; Gouble, Agnes A; Bueren, Juan A JA; Davis, Brian R BR; Segovia, Jose C JC
Publication Date: 2015-12-08
Variant appearance in text: IL1RL1: A78E; rs1041973
Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets.
Nature Communications
Witkiewicz, Agnieszka K AK; McMillan, Elizabeth A EA; Balaji, Uthra U; Baek, GuemHee G; Lin, Wan-Chi WC; Mansour, John J; Mollaee, Mehri M; Wagner, Kay-Uwe KU; Koduru, Prasad P; Yopp, Adam A; Choti, Michael A MA; Yeo, Charles J CJ; McCue, Peter P; White, Michael A MA; Knudsen, Erik S ES
Publication Date: 2015-04-09
Variant appearance in text: IL1RL1: A78E; rs1041973
Whole-genome sequencing of the world's oldest people.
Plos One
Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK
Publication Date: 2014
Variant appearance in text: IL1RL1: A78E; rs1041973
Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling.
The Journal Of Clinical Investigation
Ho, Jennifer E JE; Chen, Wei-Yu WY; Chen, Ming-Huei MH; Larson, Martin G MG; McCabe, Elizabeth L EL; Cheng, Susan S; Ghorbani, Anahita A; Coglianese, Erin E; Emilsson, Valur V; Johnson, Andrew D AD; Walter, Stefan S; Franceschini, Nora N; O'Donnell, Christopher J CJ; , ; , ; Dehghan, Abbas A; Lu, Chen C; Levy, Daniel D; Newton-Cheh, Christopher C; , ; Lin, Honghuang H; Felix, Janine F JF; Schreiter, Eric R ER; Vasan, Ramachandran S RS; Januzzi, James L JL; Lee, Richard T RT; Wang, Thomas J TJ
Publication Date: 2013-10
Variant appearance in text: IL1RL1: A78E; rs1041973
IL1RL1 gene variants and nasopharyngeal IL1RL-a levels are associated with severe RSV bronchiolitis: a multicenter cohort study.
Plos One
Faber, Tina E TE; Schuurhof, Annemieke A; Vonk, Annelies A; Koppelman, Gerard H GH; Hennus, Marije P MP; Kimpen, Jan L L JL; Janssen, Riny R; Bont, Louis J LJ
A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.
Plos Genetics
McKay, James D JD; Truong, Therese T; Gaborieau, Valerie V; Chabrier, Amelie A; Chuang, Shu-Chun SC; Byrnes, Graham G; Zaridze, David D; Shangina, Oxana O; Szeszenia-Dabrowska, Neonila N; Lissowska, Jolanta J; Rudnai, Peter P; Fabianova, Eleonora E; Bucur, Alexandru A; Bencko, Vladimir V; Holcatova, Ivana I; Janout, Vladimir V; Foretova, Lenka L; Lagiou, Pagona P; Trichopoulos, Dimitrios D; Benhamou, Simone S; Bouchardy, Christine C; Ahrens, Wolfgang W; Merletti, Franco F; Richiardi, Lorenzo L; Talamini, Renato R; Barzan, Luigi L; Kjaerheim, Kristina K; Macfarlane, Gary J GJ; Macfarlane, Tatiana V TV; Simonato, Lorenzo L; Canova, Cristina C; Agudo, Antonio A; Castellsagué, Xavier X; Lowry, Ray R; Conway, David I DI; McKinney, Patricia A PA; Healy, Claire M CM; Toner, Mary E ME; Znaor, Ariana A; Curado, Maria Paula MP; Koifman, Sergio S; Menezes, Ana A; Wünsch-Filho, Victor V; Neto, José Eluf JE; Garrote, Leticia Fernández LF; Boccia, Stefania S; Cadoni, Gabriella G; Arzani, Dario D; Olshan, Andrew F AF; Weissler, Mark C MC; Funkhouser, William K WK; Luo, Jingchun J; Lubiński, Jan J; Trubicka, Joanna J; Lener, Marcin M; Oszutowska, Dorota D; Schwartz, Stephen M SM; Chen, Chu C; Fish, Sherianne S; Doody, David R DR; Muscat, Joshua E JE; Lazarus, Philip P; Gallagher, Carla J CJ; Chang, Shen-Chih SC; Zhang, Zuo-Feng ZF; Wei, Qingyi Q; Sturgis, Erich M EM; Wang, Li-E LE; Franceschi, Silvia S; Herrero, Rolando R; Kelsey, Karl T KT; McClean, Michael D MD; Marsit, Carmen J CJ; Nelson, Heather H HH; Romkes, Marjorie M; Buch, Shama S; Nukui, Tomoko T; Zhong, Shilong S; Lacko, Martin M; Manni, Johannes J JJ; Peters, Wilbert H M WH; Hung, Rayjean J RJ; McLaughlin, John J; Vatten, Lars L; Njølstad, Inger I; Goodman, Gary E GE; Field, John K JK; Liloglou, Triantafillos T; Vineis, Paolo P; Clavel-Chapelon, Francoise F; Palli, Domenico D; Tumino, Rosario R; Krogh, Vittorio V; Panico, Salvatore S; González, Carlos A CA; Quirós, J Ramón JR; Martínez, Carmen C; Navarro, Carmen C; Ardanaz, Eva E; Larrañaga, Nerea N; Khaw, Kay-Tee KT; Key, Timothy T; Bueno-de-Mesquita, H Bas HB; Peeters, Petra H M PH; Trichopoulou, Antonia A; Linseisen, Jakob J; Boeing, Heiner H; Hallmans, Göran G; Overvad, Kim K; Tjønneland, Anne A; Kumle, Merethe M; Riboli, Elio E; Välk, Kristjan K; Vooder, Tõnu T; Voodern, Tõnu T; Metspalu, Andres A; Zelenika, Diana D; Boland, Anne A; Delepine, Marc M; Foglio, Mario M; Lechner, Doris D; Blanché, Hélène H; Gut, Ivo G IG; Galan, Pilar P; Heath, Simon S; Hashibe, Mia M; Hayes, Richard B RB; Boffetta, Paolo P; Lathrop, Mark M; Brennan, Paul P
Allelic variants of IL1R1 gene associate with severe hand osteoarthritis.
Bmc Medical Genetics
Näkki, Annu A; Kouhia, Sanna T ST; Saarela, Janna J; Harilainen, Arsi A; Tallroth, Kaj K; Videman, Tapio T; Battié, Michele C MC; Kaprio, Jaakko J; Peltonen, Leena L; Kujala, Urho M UM
Evaluation of candidate genes in a genome-wide association study of childhood asthma in Mexicans.
The Journal Of Allergy And Clinical Immunology
Wu, Hao H; Romieu, Isabelle I; Shi, Min M; Hancock, Dana B DB; Li, Huiling H; Sienra-Monge, Juan-Jose JJ; Chiu, Grace Y GY; Xu, Hong H; del Rio-Navarro, Blanca Estela BE; London, Stephanie J SJ
Asthma and genes encoding components of the vitamin D pathway.
Respiratory Research
Bossé, Yohan Y; Lemire, Mathieu M; Poon, Audrey H AH; Daley, Denise D; He, Jian-Qing JQ; Sandford, Andrew A; White, John H JH; James, Alan L AL; Musk, Arthur William AW; Palmer, Lyle J LJ; Raby, Benjamin A BA; Weiss, Scott T ST; Kozyrskyj, Anita L AL; Becker, Allan A; Hudson, Thomas J TJ; Laprise, Catherine C