Variant ID: 2-113591275-A-G

NM_000576.2(IL1B):c.100-123T>C

This variant was identified in 37 publications




Publications:


IL-1B rs2853550 polymorphism contributes to esophageal cancer susceptibility in Chinese Han population of Northwest China.

Molecular Medicine (Cambridge, Mass.)
R Zhao, X Chen, W Ren, H Dai, H Li, H Li, A Jia, Y Wu, P Han, Y Shao
Publication Date: 2020-06-11

Variant appearance in text: rs3136558
PubMed Link: 32527212
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association between IL-1 gene polymorphisms and tuberculosis susceptibility in the Chinese Tibetan population.

International Journal Of Clinical And Experimental Pathology
J Wang, T Jin, F Mo, H Dong, Y Wang, L Kang, Q Hu
Publication Date: 2018

Variant appearance in text: rs3136558
PubMed Link: 31949628
Variant Present in the following documents:
  • Main text
View BVdb publication page



Host susceptibility to severe influenza A virus infection.

Critical Care (London, England)
S Clohisey, JK Baillie
Publication Date: 2019-09-05

Variant appearance in text: rs3136558
PubMed Link: 31488196
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association between IL1B gene and cervical cancer susceptibility in Chinese Uygur Population: A Case-Control study.

Molecular Genetics & Genomic Medicine
L Wang, W Zhao, J Hong, F Niu, J Li, S Zhang, T Jin
Publication Date: 2019-08

Variant appearance in text: rs3136558
PubMed Link: 31222982
Variant Present in the following documents:
  • Main text
View BVdb publication page



Influenza Pathogenesis: The Effect of Host Factors on Severity of Disease.

Journal Of Immunology (Baltimore, Md. : 1950)
AP Gounder, ACM Boon
Publication Date: 2019-01-15

Variant appearance in text: rs3136558
PubMed Link: 30617115
Variant Present in the following documents:
  • Main text
  • nihms-1507797.pdf
View BVdb publication page



Genetic variants in genes related to inflammation, apoptosis and autophagy in breast cancer risk.

Plos One
JM Schuetz, A Grundy, DG Lee, AS Lai, LC Kobayashi, H Richardson, J Long, W Zheng, KJ Aronson, JJ Spinelli, AR Brooks-Wilson
Publication Date: 2019

Variant appearance in text: rs3136558
PubMed Link: 30601841
Variant Present in the following documents:
  • pone.0209010.s001.pdf
View BVdb publication page



Interleukin-1 Receptor Antagonist Is Associated With Pediatric Acute Respiratory Distress Syndrome and Worse Outcomes in Children With Acute Respiratory Failure.

Pediatric Critical Care Medicine : A Journal Of The Society Of Critical Care Medicine And The World Federation Of Pediatric Intensive And Critical Care Societies
MK Dahmer, MW Quasney, A Sapru, G Gildengorin, MAQ Curley, MA Matthay, H Flori,
Publication Date: 2018-10

Variant appearance in text: rs3136558
PubMed Link: 30095747
Variant Present in the following documents:
  • NIHMS980151-supplement-Supplemental_Data_File___doc___tif__pdf__etc__.docx
View BVdb publication page



Association Between Polymorphisms of Interleukin 1 Family Genes and Hepatocellular Carcinoma.

Medical Science Monitor : International Medical Journal Of Experimental And Clinical Research
KH Tak, GI Yu, MY Lee, DH Shin
Publication Date: 2018-05-26

Variant appearance in text: rs3136558
PubMed Link: 29802240
Variant Present in the following documents:
  • Main text
View BVdb publication page



Interleukin gene polymorphisms in Chinese Han population with breast cancer, a case-control study.

Oncotarget
X Zuo, M Li, Y Yang, T Liang, H Yang, X Zhao, D Yang
Publication Date: 2018-04-06

Variant appearance in text: rs3136558
PubMed Link: 29719585
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-wide association study for pollinosis identified two novel loci in interleukin (IL)-1B in a Japanese population.

Nagoya Journal Of Medical Science
R Fujii, A Hishida, MC Wu, T Kondo, Y Hattori, M Naito, K Endoh, M Nakatochi, N Hamajima, M Kubo, K Kuriki, K Wakai
Publication Date: 2018-02

Variant appearance in text: rs3136558
PubMed Link: 29581620
Variant Present in the following documents:
  • Main text
View BVdb publication page



Determination of IL-1B (rs16944) and IL-6 (rs1800796) genetic polymorphisms in IgA nephropathy in a northwest Chinese Han population.

Oncotarget
D Zhang, M Xie, X Yang, Y Zhang, Y Su, Y Wang, H Huang, H Han, W Li, K Fu, H Su, W Xu, Y Han, R Wang, P Zhang, W Wu, Y Huang, D Chen, T Jin, J Wei
Publication Date: 2017-09-22

Variant appearance in text: rs3136558
PubMed Link: 29069743
Variant Present in the following documents:
  • Main text
View BVdb publication page



IL1 genes polymorphism and the risk of renal cell carcinoma in Chinese Han population.

Oncotarget
F Wang, Y Zhang, S Wang, Y Zhang, D Wu, C Zhang, Y Gao, X Liu, W Wang, S Zhang
Publication Date: 2017-08-22

Variant appearance in text: rs3136558
PubMed Link: 28915570
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of anti-inflammatory cytokine IL10 polymorphisms with motoric cognitive risk syndrome in an Ashkenazi Jewish population.

Neurobiology Of Aging
S Sathyan, N Barzilai, G Atzmon, S Milman, E Ayers, J Verghese
Publication Date: 2017-10

Variant appearance in text: rs3136558
PubMed Link: 28705468
Variant Present in the following documents:
  • Main text
  • NIHMS886142-supplement-2.docx
View BVdb publication page



Investigation of DNA repair-related SNPs underlying susceptibility to papillary thyroid carcinoma reveals MGMT as a novel candidate gene in Belarusian children exposed to radiation.

Bmc Cancer
C Lonjou, F Damiola, M Moissonnier, G Durand, I Malakhova, V Masyakin, F Le Calvez-Kelm, E Cardis, G Byrnes, A Kesminiene, F Lesueur
Publication Date: 2017-05-12

Variant appearance in text: rs3136558
PubMed Link: 28499365
Variant Present in the following documents:
  • 12885_2017_3314_MOESM1_ESM.xls
View BVdb publication page



Genetic factors in pathogenesis of diabetes mellitus after kidney transplantation.

Therapeutics And Clinical Risk Management
M Tarnowski, S Słuczanowska-Głabowska, A Pawlik, M Mazurek-Mochol, E Dembowska
Publication Date: 2017

Variant appearance in text: rs3136558
PubMed Link: 28435278
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of IL-1A and IL-1B polymorphisms with ankylosing spondylitis among the Chinese Han population: a case-control study.

Oncotarget
L Li, B Shi, W Zheng, W Xing, Y Zhao, F Li, D Xin, T Jin, Y Zhu, X Yang
Publication Date: 2017-04-25

Variant appearance in text: rs3136558
PubMed Link: 28423679
Variant Present in the following documents:
  • Main text
View BVdb publication page



Population genetics of immune-related multilocus copy number variation in Native Americans.

Journal Of The Royal Society, Interface
LW Zuccherato, S Schneider, E Tarazona-Santos, RJ Hardwick, DE Berg, H Bogle, MH Gouveia, LR Machado, M Machado, F Rodrigues-Soares, GB Soares-Souza, DL Togni, R Zamudio, RH Gilman, D Duarte, EJ Hollox, MR Rodrigues
Publication Date: 2017-03

Variant appearance in text: rs3136558
PubMed Link: 28356540
Variant Present in the following documents:
  • rsif20170057supp1.doc
View BVdb publication page



Genetic dissection of host immune response in pneumonia development and progression.

Scientific Reports
TV Smelaya, OB Belopolskaya, SV Smirnova, AN Kuzovlev, VV Moroz, AM Golubev, NA Pabalan, LE Salnikova
Publication Date: 2016-10-11

Variant appearance in text: rs3136558
PubMed Link: 27725770
Variant Present in the following documents:
  • srep35021-s1.pdf
View BVdb publication page



Expression and Sequence Variants of Inflammatory Genes; Effects on Plasma Inflammation Biomarkers Following a 6-Week Supplementation with Fish Oil.

International Journal Of Molecular Sciences
H Cormier, I Rudkowska, S Lemieux, P Couture, MC Vohl
Publication Date: 2016-03-15

Variant appearance in text: rs3136558
PubMed Link: 26999109
Variant Present in the following documents:
  • Main text
View BVdb publication page



TNF, IL6, and IL1B Polymorphisms Are Associated with Severe Influenza A (H1N1) Virus Infection in the Mexican Population.

Plos One
RA García-Ramírez, A Ramírez-Venegas, R Quintana-Carrillo, ÁE Camarena, R Falfán-Valencia, JM Mejía-Aranguré
Publication Date: 2015

Variant appearance in text: rs3136558
PubMed Link: 26657940
Variant Present in the following documents:
  • Main text
  • pone.0144832.s001.pdf
  • pone.0144832.s002.pdf
  • pone.0144832.s003.pdf
View BVdb publication page



Epistasis analysis links immune cascades and cerebral amyloidosis.

Journal Of Neuroinflammation
AL Benedet, A Labbe, P Lemay, ER Zimmer, TA Pascoal, A Leuzy, S Mathotaarachchi, S Mohades, M Shin, A Dionne-Laporte, T Beaudry, C Picard, S Gauthier, J Poirier, G Rouleau, P Rosa-Neto,
Publication Date: 2015-12-01

Variant appearance in text: rs3136558
PubMed Link: 26626881
Variant Present in the following documents:
  • 12974_2015_436_MOESM2_ESM.docx
View BVdb publication page



A population-based case-control study of genetic variation in cytokine genes associated with risk of cervical and vulvar cancers.

Gynecologic Oncology
S Hardikar, LG Johnson, M Malkki, EW Petersdorf, DA Galloway, SM Schwartz, MM Madeleine
Publication Date: 2015-10

Variant appearance in text: rs3136558
PubMed Link: 26241630
Variant Present in the following documents:
  • NIHMS716539-supplement.xlsx
View BVdb publication page



Oesophageal squamous cell carcinoma in high-risk Chinese populations: Possible role for vascular epithelial growth factor A.

European Journal Of Cancer (Oxford, England : 1990)
A Golozar, TH Beaty, PE Gravitt, I Ruczinski, YL Qiao, JH Fan, T Ding, ZZ Tang, A Etemadi, N Hu, PL Hyland, L Wang, C Wang, SM Dawsey, ND Freedman, CC Abnet, AM Goldstein, PR Taylor
Publication Date: 2014-11

Variant appearance in text: rs3136558
PubMed Link: 25172294
Variant Present in the following documents:
  • NIHMS624582-supplement-Supplement.docx
View BVdb publication page



Apoptosis-Related Single Nucleotide Polymorphisms and the Risk of Non-Small Cell Lung Cancer in Women.

Journal Of Cancer Therapeutics & Research
A Pathak, AS Wenzlaff, PL Hyland, ML Cote, GR Keele, S Land, ML Boulton, AG Schwartz
Publication Date: 2014

Variant appearance in text: rs3136558
PubMed Link: 24790730
Variant Present in the following documents:
  • NIHMS559787-supplement-Supplementary_Table_1.doc
View BVdb publication page



IL-1β associations with posttraumatic epilepsy development: a genetics and biomarker cohort study.

Epilepsia
ML Diamond, AC Ritter, MD Failla, JA Boles, YP Conley, PM Kochanek, AK Wagner
Publication Date: 2014-07

Variant appearance in text: rs3136558
PubMed Link: 24754437
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetics of new-onset diabetes after transplantation.

Journal Of The American Society Of Nephrology : Jasn
JA McCaughan, AJ McKnight, AP Maxwell
Publication Date: 2014-05

Variant appearance in text: rs3136558
PubMed Link: 24309190
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mental quality of life is related to a cytokine genetic pathway.

Plos One
D Schoormans, T Radonic, P de Witte, M Groenink, D Azim, R Lutter, BJ Mulder, MA Sprangers, AH Zwinderman
Publication Date: 2012

Variant appearance in text: rs3136558
PubMed Link: 23049769
Variant Present in the following documents:
  • pone.0045126.s004.xls
View BVdb publication page



Impact of cytokine and cytokine receptor gene polymorphisms on cellular immunity after smallpox vaccination.

Gene
IG Ovsyannikova, IH Haralambieva, RB Kennedy, VS Pankratz, RA Vierkant, RM Jacobson, GA Poland
Publication Date: 2012-11-15

Variant appearance in text: rs3136558
PubMed Link: 23009887
Variant Present in the following documents:
  • NIHMS402815-supplement-supplement_1.pdf
View BVdb publication page



Multigenic control of measles vaccine immunity mediated by polymorphisms in measles receptor, innate pathway, and cytokine genes.

Vaccine
RB Kennedy, IG Ovsyannikova, IH Haralambieva, MM O'Byrne, RM Jacobson, VS Pankratz, GA Poland
Publication Date: 2012-03-09

Variant appearance in text: rs3136558
PubMed Link: 22265947
Variant Present in the following documents:
  • NIHMS350206-supplement-01.doc
View BVdb publication page



Identifying host genetic risk factors in the context of public health surveillance for invasive pneumococcal disease.

Plos One
JR Lingappa, L Dumitrescu, SM Zimmer, R Lynfield, JM McNicholl, NE Messonnier, CG Whitney, DC Crawford
Publication Date: 2011

Variant appearance in text: rs3136558
PubMed Link: 21858107
Variant Present in the following documents:
  • pone.0023413.s001.doc
  • pone.0023413.s004.doc
View BVdb publication page



Cytokine and cytokine receptor single-nucleotide polymorphisms predict risk for non-small cell lung cancer among women.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
AL Van Dyke, ML Cote, AS Wenzlaff, W Chen, J Abrams, S Land, CN Giroux, AG Schwartz
Publication Date: 2009-06

Variant appearance in text: rs3136558
PubMed Link: 19505916
Variant Present in the following documents:
  • Main text
View BVdb publication page



Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies.

Cytokine
AL Van Dyke, ML Cote, AS Wenzlaff, S Land, AG Schwartz
Publication Date: 2009-05

Variant appearance in text: rs3136558
PubMed Link: 19356949
Variant Present in the following documents:
  • Main text
View BVdb publication page



Complexity in the genetic architecture of leukoaraiosis in hypertensive sibships from the GENOA Study.

Bmc Medical Genomics
JA Smith, ST Turner, YV Sun, M Fornage, RJ Kelly, TH Mosley, CR Jack, IJ Kullo, SL Kardia
Publication Date: 2009-04-07

Variant appearance in text: rs3136558
PubMed Link: 19351393
Variant Present in the following documents:
  • 1755-8794-2-16-S1.xls
View BVdb publication page



Interactions between metallopeptidase 3 polymorphism rs679620 and BMI in predicting blood pressure in African-American women with hypertension.

Journal Of Hypertension
J Taylor, YV Sun, J Chu, TH Mosley, SL Kardia
Publication Date: 2008-12

Variant appearance in text: rs3136558
PubMed Link: 19008710
Variant Present in the following documents:
  • NIHMS254027-supplement-supplemental_table.doc
View BVdb publication page



Genetic associations with schizophrenia: meta-analyses of 12 candidate genes.

Schizophrenia Research
J Shi, ES Gershon, C Liu
Publication Date: 2008-09

Variant appearance in text: rs3136558
PubMed Link: 18715757
Variant Present in the following documents:
  • NIHMS59748-supplement-7.doc
View BVdb publication page



Investigating the complex genetic architecture of ankle-brachial index, a measure of peripheral arterial disease, in non-Hispanic whites.

Bmc Medical Genomics
SL Kardia, MT Greene, E Boerwinkle, ST Turner, IJ Kullo
Publication Date: 2008-05-15

Variant appearance in text: rs3136558
PubMed Link: 18482449
Variant Present in the following documents:
  • 1755-8794-1-16-S1.pdf
View BVdb publication page



Variation in inflammation-related genes and risk of incident nonfatal myocardial infarction or ischemic stroke.

Atherosclerosis
JC Bis, SR Heckbert, NL Smith, AP Reiner, K Rice, T Lumley, LA Hindorff, KD Marciante, DA Enquobahrie, SA Monks, BM Psaty
Publication Date: 2008-05

Variant appearance in text: rs3136558
PubMed Link: 17981284
Variant Present in the following documents:
  • Main text
View BVdb publication page



Alternative transcript annotations:

Transcript cDNA Protein Consequence Exon Intron
ENST00000263341.2 c.100-123T>C - intron_variant - 3/6
ENST00000416750.1 c.100-123T>C - intron_variant - 3/4
ENST00000418817.1 c.100-123T>C - intron_variant - 3/4
ENST00000432018.1 c.100-123T>C - intron_variant - 2/3
ENST00000491056.1 n.650-123T>C - intron_variant,non_coding_transcript_variant - 2/5
ENST00000496280.1 n.187-123T>C - intron_variant,non_coding_transcript_variant - 3/3
NM_000576.3 c.100-123T>C - intron_variant - 3/6