Blood pressure lowering and risk of new-onset type 2 diabetes: an individual participant data meta-analysis.
Lancet (London, England)
Nazarzadeh, Milad M; Bidel, Zeinab Z; Canoy, Dexter D; Copland, Emma E; Wamil, Malgorzata M; Majert, Jeannette J; Smith Byrne, Karl K; Sundström, Johan J; Teo, Koon K; Davis, Barry R BR; Chalmers, John J; Pepine, Carl J CJ; Dehghan, Abbas A; Bennett, Derrick A DA; Smith, George Davey GD; Rahimi, Kazem K; ,
Variant rs6749447 (T > G) in the serine threonine kinase gene is associated with cardiovascular complications, the Tampere adult population cardiovascular risk study.
Medicine
Kunnas, Tarja T; Määttä, Kirsi K; Nikkari, Seppo T ST
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
Nature Genetics
Evangelou, Evangelos E; Warren, Helen R HR; Mosen-Ansorena, David D; Mifsud, Borbala B; Pazoki, Raha R; Gao, He H; Ntritsos, Georgios G; Dimou, Niki N; Cabrera, Claudia P CP; Karaman, Ibrahim I; Ng, Fu Liang FL; Evangelou, Marina M; Witkowska, Katarzyna K; Tzanis, Evan E; Hellwege, Jacklyn N JN; Giri, Ayush A; Velez Edwards, Digna R DR; Sun, Yan V YV; Cho, Kelly K; Gaziano, J Michael JM; Wilson, Peter W F PWF; Tsao, Philip S PS; Kovesdy, Csaba P CP; Esko, Tonu T; Mägi, Reedik R; Milani, Lili L; Almgren, Peter P; Boutin, Thibaud T; Debette, Stéphanie S; Ding, Jun J; Giulianini, Franco F; Holliday, Elizabeth G EG; Jackson, Anne U AU; Li-Gao, Ruifang R; Lin, Wei-Yu WY; Luan, Jian'an J; Mangino, Massimo M; Oldmeadow, Christopher C; Prins, Bram Peter BP; Qian, Yong Y; Sargurupremraj, Muralidharan M; Shah, Nabi N; Surendran, Praveen P; Thériault, Sébastien S; Verweij, Niek N; Willems, Sara M SM; Zhao, Jing-Hua JH; Amouyel, Philippe P; Connell, John J; de Mutsert, Renée R; Doney, Alex S F ASF; Farrall, Martin M; Menni, Cristina C; Morris, Andrew D AD; Noordam, Raymond R; Paré, Guillaume G; Poulter, Neil R NR; Shields, Denis C DC; Stanton, Alice A; Thom, Simon S; Abecasis, Gonçalo G; Amin, Najaf N; Arking, Dan E DE; Ayers, Kristin L KL; Barbieri, Caterina M CM; Batini, Chiara C; Bis, Joshua C JC; Blake, Tineka T; Bochud, Murielle M; Boehnke, Michael M; Boerwinkle, Eric E; Boomsma, Dorret I DI; Bottinger, Erwin P EP; Braund, Peter S PS; Brumat, Marco M; Campbell, Archie A; Campbell, Harry H; Chakravarti, Aravinda A; Chambers, John C JC; Chauhan, Ganesh G; Ciullo, Marina M; Cocca, Massimiliano M; Collins, Francis F; Cordell, Heather J HJ; Davies, Gail G; de Borst, Martin H MH; de Geus, Eco J EJ; Deary, Ian J IJ; Deelen, Joris J; Del Greco M, Fabiola F; Demirkale, Cumhur Yusuf CY; Dörr, Marcus M; Ehret, Georg B GB; Elosua, Roberto R; Enroth, Stefan S; Erzurumluoglu, A Mesut AM; Ferreira, Teresa T; Frånberg, Mattias M; Franco, Oscar H OH; Gandin, Ilaria I; Gasparini, Paolo P; Giedraitis, Vilmantas V; Gieger, Christian C; Girotto, Giorgia G; Goel, Anuj A; Gow, Alan J AJ; Gudnason, Vilmundur V; Guo, Xiuqing X; Gyllensten, Ulf U; Hamsten, Anders A; Harris, Tamara B TB; Harris, Sarah E SE; Hartman, Catharina A CA; Havulinna, Aki S AS; Hicks, Andrew A AA; Hofer, Edith E; Hofman, Albert A; Hottenga, Jouke-Jan JJ; Huffman, Jennifer E JE; Hwang, Shih-Jen SJ; Ingelsson, Erik E; James, Alan A; Jansen, Rick R; Jarvelin, Marjo-Riitta MR; Joehanes, Roby R; Johansson, Åsa Å; Johnson, Andrew D AD; Joshi, Peter K PK; Jousilahti, Pekka P; Jukema, J Wouter JW; Jula, Antti A; Kähönen, Mika M; Kathiresan, Sekar S; Keavney, Bernard D BD; Khaw, Kay-Tee KT; Knekt, Paul P; Knight, Joanne J; Kolcic, Ivana I; Kooner, Jaspal S JS; Koskinen, Seppo S; Kristiansson, Kati K; Kutalik, Zoltan Z; Laan, Maris M; Larson, Marty M; Launer, Lenore J LJ; Lehne, Benjamin B; Lehtimäki, Terho T; Liewald, David C M DCM; Lin, Li L; Lind, Lars L; Lindgren, Cecilia M CM; Liu, YongMei Y; Loos, Ruth J F RJF; Lopez, Lorna M LM; Lu, Yingchang Y; Lyytikäinen, Leo-Pekka LP; Mahajan, Anubha A; Mamasoula, Chrysovalanto C; Marrugat, Jaume J; Marten, Jonathan J; Milaneschi, Yuri Y; Morgan, Anna A; Morris, Andrew P AP; Morrison, Alanna C AC; Munson, Peter J PJ; Nalls, Mike A MA; Nandakumar, Priyanka P; Nelson, Christopher P CP; Niiranen, Teemu T; Nolte, Ilja M IM; Nutile, Teresa T; Oldehinkel, Albertine J AJ; Oostra, Ben A BA; O'Reilly, Paul F PF; Org, Elin E; Padmanabhan, Sandosh S; Palmas, Walter W; Palotie, Aarno A; Pattie, Alison A; Penninx, Brenda W J H BWJH; Perola, Markus M; Peters, Annette A; Polasek, Ozren O; Pramstaller, Peter P PP; Nguyen, Quang Tri QT; Raitakari, Olli T OT; Ren, Meixia M; Rettig, Rainer R; Rice, Kenneth K; Ridker, Paul M PM; Ried, Janina S JS; Riese, Harriëtte H; Ripatti, Samuli S; Robino, Antonietta A; Rose, Lynda M LM; Rotter, Jerome I JI; Rudan, Igor I; Ruggiero, Daniela D; Saba, Yasaman Y; Sala, Cinzia F CF; Salomaa, Veikko V; Samani, Nilesh J NJ; Sarin, Antti-Pekka AP; Schmidt, Reinhold R; Schmidt, Helena H; Shrine, Nick N; Siscovick, David D; Smith, Albert V AV; Snieder, Harold H; Sõber, Siim S; Sorice, Rossella R; Starr, John M JM; Stott, David J DJ; Strachan, David P DP; Strawbridge, Rona J RJ; Sundström, Johan J; Swertz, Morris A MA; Taylor, Kent D KD; Teumer, Alexander A; Tobin, Martin D MD; Tomaszewski, Maciej M; Toniolo, Daniela D; Traglia, Michela M; Trompet, Stella S; Tuomilehto, Jaakko J; Tzourio, Christophe C; Uitterlinden, André G AG; Vaez, Ahmad A; van der Most, Peter J PJ; van Duijn, Cornelia M CM; Vergnaud, Anne-Claire AC; Verwoert, Germaine C GC; Vitart, Veronique V; Völker, Uwe U; Vollenweider, Peter P; Vuckovic, Dragana D; Watkins, Hugh H; Wild, Sarah H SH; Willemsen, Gonneke G; Wilson, James F JF; Wright, Alan F AF; Yao, Jie J; Zemunik, Tatijana T; Zhang, Weihua W; Attia, John R JR; Butterworth, Adam S AS; Chasman, Daniel I DI; Conen, David D; Cucca, Francesco F; Danesh, John J; Hayward, Caroline C; Howson, Joanna M M JMM; Laakso, Markku M; Lakatta, Edward G EG; Langenberg, Claudia C; Melander, Olle O; Mook-Kanamori, Dennis O DO; Palmer, Colin N A CNA; Risch, Lorenz L; Scott, Robert A RA; Scott, Rodney J RJ; Sever, Peter P; Spector, Tim D TD; van der Harst, Pim P; Wareham, Nicholas J NJ; Zeggini, Eleftheria E; Levy, Daniel D; Munroe, Patricia B PB; Newton-Cheh, Christopher C; Brown, Morris J MJ; Metspalu, Andres A; Hung, Adriana M AM; O'Donnell, Christopher J CJ; Edwards, Todd L TL; Psaty, Bruce M BM; Tzoulaki, Ioanna I; Barnes, Michael R MR; Wain, Louise V LV; Elliott, Paul P; Caulfield, Mark J MJ; ,
Towards Precision Medicine for Hypertension: A Review of Genomic, Epigenomic, and Microbiomic Effects on Blood Pressure in Experimental Rat Models and Humans.
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.
Hypertension (Dallas, Tex. : 1979)
Wain, Louise V LV; Vaez, Ahmad A; Jansen, Rick R; Joehanes, Roby R; van der Most, Peter J PJ; Erzurumluoglu, A Mesut AM; O'Reilly, Paul F PF; Cabrera, Claudia P CP; Warren, Helen R HR; Rose, Lynda M LM; Verwoert, Germaine C GC; Hottenga, Jouke-Jan JJ; Strawbridge, Rona J RJ; Esko, Tonu T; Arking, Dan E DE; Hwang, Shih-Jen SJ; Guo, Xiuqing X; Kutalik, Zoltan Z; Trompet, Stella S; Shrine, Nick N; Teumer, Alexander A; Ried, Janina S JS; Bis, Joshua C JC; Smith, Albert V AV; Amin, Najaf N; Nolte, Ilja M IM; Lyytikäinen, Leo-Pekka LP; Mahajan, Anubha A; Wareham, Nicholas J NJ; Hofer, Edith E; Joshi, Peter K PK; Kristiansson, Kati K; Traglia, Michela M; Havulinna, Aki S AS; Goel, Anuj A; Nalls, Mike A MA; Sõber, Siim S; Vuckovic, Dragana D; Luan, Jian'an J; Del Greco M, Fabiola F; Ayers, Kristin L KL; Marrugat, Jaume J; Ruggiero, Daniela D; Lopez, Lorna M LM; Niiranen, Teemu T; Enroth, Stefan S; Jackson, Anne U AU; Nelson, Christopher P CP; Huffman, Jennifer E JE; Zhang, Weihua W; Marten, Jonathan J; Gandin, Ilaria I; Harris, Sarah E SE; Zemunik, Tatijana T; Lu, Yingchang Y; Evangelou, Evangelos E; Shah, Nabi N; de Borst, Martin H MH; Mangino, Massimo M; Prins, Bram P BP; Campbell, Archie A; Li-Gao, Ruifang R; Chauhan, Ganesh G; Oldmeadow, Christopher C; Abecasis, Gonçalo G; Abedi, Maryam M; Barbieri, Caterina M CM; Barnes, Michael R MR; Batini, Chiara C; Beilby, John J; Blake, Tineka T; Boehnke, Michael M; Bottinger, Erwin P EP; Braund, Peter S PS; Brown, Morris M; Brumat, Marco M; Campbell, Harry H; Chambers, John C JC; Cocca, Massimiliano M; Collins, Francis F; Connell, John J; Cordell, Heather J HJ; Damman, Jeffrey J JJ; Davies, Gail G; de Geus, Eco J EJ; de Mutsert, Renée R; Deelen, Joris J; Demirkale, Yusuf Y; Doney, Alex S F ASF; Dörr, Marcus M; Farrall, Martin M; Ferreira, Teresa T; Frånberg, Mattias M; Gao, He H; Giedraitis, Vilmantas V; Gieger, Christian C; Giulianini, Franco F; Gow, Alan J AJ; Hamsten, Anders A; Harris, Tamara B TB; Hofman, Albert A; Holliday, Elizabeth G EG; Hui, Jennie J; Jarvelin, Marjo-Riitta MR; Johansson, Åsa Å; Johnson, Andrew D AD; Jousilahti, Pekka P; Jula, Antti A; Kähönen, Mika M; Kathiresan, Sekar S; Khaw, Kay-Tee KT; Kolcic, Ivana I; Koskinen, Seppo S; Langenberg, Claudia C; Larson, Marty M; Launer, Lenore J LJ; Lehne, Benjamin B; Liewald, David C M DCM; Lin, Li L; Lind, Lars L; Mach, François F; Mamasoula, Chrysovalanto C; Menni, Cristina C; Mifsud, Borbala B; Milaneschi, Yuri Y; Morgan, Anna A; Morris, Andrew D AD; Morrison, Alanna C AC; Munson, Peter J PJ; Nandakumar, Priyanka P; Nguyen, Quang Tri QT; Nutile, Teresa T; Oldehinkel, Albertine J AJ; Oostra, Ben A BA; Org, Elin E; Padmanabhan, Sandosh S; Palotie, Aarno A; Paré, Guillaume G; Pattie, Alison A; Penninx, Brenda W J H BWJH; Poulter, Neil N; Pramstaller, Peter P PP; Raitakari, Olli T OT; Ren, Meixia M; Rice, Kenneth K; Ridker, Paul M PM; Riese, Harriëtte H; Ripatti, Samuli S; Robino, Antonietta A; Rotter, Jerome I JI; Rudan, Igor I; Saba, Yasaman Y; Saint Pierre, Aude A; Sala, Cinzia F CF; Sarin, Antti-Pekka AP; Schmidt, Reinhold R; Scott, Rodney R; Seelen, Marc A MA; Shields, Denis C DC; Siscovick, David D; Sorice, Rossella R; Stanton, Alice A; Stott, David J DJ; Sundström, Johan J; Swertz, Morris M; Taylor, Kent D KD; Thom, Simon S; Tzoulaki, Ioanna I; Tzourio, Christophe C; Uitterlinden, André G AG; Völker, Uwe U; Vollenweider, Peter P; Wild, Sarah S; Willemsen, Gonneke G; Wright, Alan F AF; Yao, Jie J; Thériault, Sébastien S; Conen, David D; Attia, John J; Sever, Peter P; Debette, Stéphanie S; Mook-Kanamori, Dennis O DO; Zeggini, Eleftheria E; Spector, Tim D TD; van der Harst, Pim P; Palmer, Colin N A CNA; Vergnaud, Anne-Claire AC; Loos, Ruth J F RJF; Polasek, Ozren O; Starr, John M JM; Girotto, Giorgia G; Hayward, Caroline C; Kooner, Jaspal S JS; Lindgren, Cecila M CM; Vitart, Veronique V; Samani, Nilesh J NJ; Tuomilehto, Jaakko J; Gyllensten, Ulf U; Knekt, Paul P; Deary, Ian J IJ; Ciullo, Marina M; Elosua, Roberto R; Keavney, Bernard D BD; Hicks, Andrew A AA; Scott, Robert A RA; Gasparini, Paolo P; Laan, Maris M; Liu, YongMei Y; Watkins, Hugh H; Hartman, Catharina A CA; Salomaa, Veikko V; Toniolo, Daniela D; Perola, Markus M; Wilson, James F JF; Schmidt, Helena H; Zhao, Jing Hua JH; Lehtimäki, Terho T; van Duijn, Cornelia M CM; Gudnason, Vilmundur V; Psaty, Bruce M BM; Peters, Annette A; Rettig, Rainer R; James, Alan A; Jukema, J Wouter JW; Strachan, David P DP; Palmas, Walter W; Metspalu, Andres A; Ingelsson, Erik E; Boomsma, Dorret I DI; Franco, Oscar H OH; Bochud, Murielle M; Newton-Cheh, Christopher C; Munroe, Patricia B PB; Elliott, Paul P; Chasman, Daniel I DI; Chakravarti, Aravinda A; Knight, Joanne J; Morris, Andrew P AP; Levy, Daniel D; Tobin, Martin D MD; Snieder, Harold H; Caulfield, Mark J MJ; Ehret, Georg B GB
Potential role of gene-environment interactions in ion transport mechanisms in the etiology of renal cell cancer.
Scientific Reports
Deckers, Ivette A G IA; van den Brandt, Piet A PA; van Engeland, Manon M; van Schooten, Frederik J FJ; Godschalk, Roger W L RW; Keszei, András P AP; Hogervorst, Janneke G F JG; Schouten, Leo J LJ
TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.
Journal Of Hypertension
Chittani, Martina M; Zaninello, Roberta R; Lanzani, Chiara C; Frau, Francesca F; Ortu, Maria F MF; Salvi, Erika E; Fresu, Giovanni G; Citterio, Lorena L; Braga, Daniele D; Piras, Daniela A DA; Carpini, Simona Delli SD; Velayutham, Dinesh D; Simonini, Marco M; Argiolas, Giuseppe G; Pozzoli, Simona S; Troffa, Chiara C; Glorioso, Valeria V; Kontula, Kimmo K KK; Hiltunen, Timo P TP; Donner, Kati M KM; Turner, Stephen T ST; Boerwinkle, Eric E; Chapman, Arlene B AB; Padmanabhan, Sandosh S; Dominiczak, Anna F AF; Melander, Olle O; Johnson, Julie A JA; Cooper-Dehoff, Rhonda M RM; Gong, Yan Y; Rivera, Natalia V NV; Condorelli, Gianluigi G; Trimarco, Bruno B; Manunta, Paolo P; Cusi, Daniele D; Glorioso, Nicola N; Barlassina, Cristina C
Extracellular water and blood pressure in adults with growth hormone (GH) deficiency: a genotype-phenotype association study.
Plos One
Barbosa, Edna J L EJ; Glad, Camilla A M CA; Nilsson, Anna G AG; Bosaeus, Niklas N; Nyström, Helena Filipsson HF; Svensson, Per-Arne PA; Bengtsson, Bengt-Åke BÅ; Nilsson, Staffan S; Bosaeus, Ingvar I; Boguszewski, Cesar Luiz CL; Johannsson, Gudmundur G
Salt sensitivity of blood pressure is associated with polymorphisms in the sodium-bicarbonate cotransporter.
Hypertension (Dallas, Tex. : 1979)
Carey, Robert M RM; Schoeffel, Cynthia D CD; Gildea, John J JJ; Jones, John E JE; McGrath, Helen E HE; Gordon, Lindsay N LN; Park, Min Jeong MJ; Sobota, Rafal S RS; Underwood, Patricia C PC; Williams, Jonathan J; Sun, Bei B; Raby, Benjamin B; Lasky-Su, Jessica J; Hopkins, Paul N PN; Adler, Gail K GK; Williams, Scott M SM; Jose, Pedro A PA; Felder, Robin A RA
Lack of association between polymorphisms in STK39, a putative thiazide response gene, and blood pressure response to hydrochlorothiazide.
Pharmacogenetics And Genomics
Duarte, Julio D JD; Lobmeyer, Maximilian T MT; Wang, Zhiying Z; Chapman, Arlene B AB; Gums, John G JG; Langaee, Taimour Y TY; Boerwinkle, Eric E; Turner, Stephen T ST; Johnson, Julie A JA
From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Wang, Ying Y; O'Connell, Jeffrey R JR; McArdle, Patrick F PF; Wade, James B JB; Dorff, Sarah E SE; Shah, Sanjiv J SJ; Shi, Xiaolian X; Pan, Lin L; Rampersaud, Evadnie E; Shen, Haiqing H; Kim, James D JD; Subramanya, Arohan R AR; Steinle, Nanette I NI; Parsa, Afshin A; Ober, Carole C CC; Welling, Paul A PA; Chakravarti, Aravinda A; Weder, Alan B AB; Cooper, Richard S RS; Mitchell, Braxton D BD; Shuldiner, Alan R AR; Chang, Yen-Pei C YP