IDH1 c.394_395delinsTT ;(p.R132F)

Variant ID: 2-209113112-CG-AA

NM_005896.2(IDH1):c.394_395delinsTT;(p.R132F)

This variant was identified in 9 publications

View GRCh38 version.




Publications:


Secondary IDH1 resistance mutations and oncogenic IDH2 mutations cause acquired resistance to ivosidenib in cholangiocarcinoma.

Npj Precision Oncology
Cleary, James M JM; Rouaisnel, Betty B; Daina, Antoine A; Raghavan, Srivatsan S; Roller, Lauren A LA; Huffman, Brandon M BM; Singh, Harshabad H; Wen, Patrick Y PY; Bardeesy, Nabeel N; Zoete, Vincent V; Wolpin, Brian M BM; Losman, Julie-Aurore JA
Publication Date: 2022-09-02

Variant appearance in text: IDH1: R132F
PubMed Link: 36056177
Variant Present in the following documents:
  • Main text
  • 41698_2022_Article_304.pdf
View BVdb publication page



Prognostic importance of IDH mutations in chondrosarcoma: An individual patient data meta-analysis.

Cancer Medicine
Vuong, Huy Gia HG; Ngo, Tam N M TNM; Dunn, Ian F IF
Publication Date: 2021-07

Variant appearance in text: IDH1: R132F
PubMed Link: 34085407
Variant Present in the following documents:
  • Main text
  • CAM4-10-4415.pdf
View BVdb publication page



Outcome of patients with IDH1/2-mutated post-myeloproliferative neoplasm AML in the era of IDH inhibitors.

Blood Advances
Chifotides, Helen T HT; Masarova, Lucia L; Alfayez, Mansour M; Daver, Naval N; Alvarado, Yesid Y; Jabbour, Elias E; Konopleva, Marina M; Kantarjian, Hagop M HM; Patel, Keyur P KP; DiNardo, Courtney D CD; Verstovsek, Srdan S
Publication Date: 2020-11-10

Variant appearance in text: IDH1: R132F
PubMed Link: 33112940
Variant Present in the following documents:
  • Main text
View BVdb publication page



Clonality analysis and IDH1 and IDH2 mutation detection in both components of dedifferentiated chondrosarcoma, implicated its monoclonal origin.

Journal Of Bone Oncology
Yang, Tingting T; Bai, Yueqing Y; Chen, Jie J; Sun, Keyang K; Luo, Yanli Y; Huang, Wentao W; Zhang, Huizhen H
Publication Date: 2020-06

Variant appearance in text: IDH1: R132F
PubMed Link: 32742915
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Targets for therapy in biliary tract cancers: the new horizon of personalized medicine.

Chinese Clinical Oncology
Iyer, Pritish P; Chen, Ming-Huang MH; Goyal, Lipika L; Denlinger, Crystal S CS
Publication Date: 2020-02

Variant appearance in text: IDH1: R132F
PubMed Link: 32146818
Variant Present in the following documents:
  • Main text
View BVdb publication page



Safety and activity of ivosidenib in patients with IDH1-mutant advanced cholangiocarcinoma: a phase 1 study.

The Lancet. Gastroenterology & Hepatology
Lowery, Maeve A MA; Burris, Howard A HA; Janku, Filip F; Shroff, Rachna T RT; Cleary, James M JM; Azad, Nilofer S NS; Goyal, Lipika L; Maher, Elizabeth A EA; Gore, Lia L; Hollebecque, Antoine A; Beeram, Muralidhar M; Trent, Jonathan C JC; Jiang, Liewen L; Fan, Bin B; Aguado-Fraile, Elia E; Choe, Sung S; Wu, Bin B; Gliser, Camelia C; Agresta, Samuel V SV; Pandya, Shuchi S SS; Zhu, Andrew X AX; Abou-Alfa, Ghassan K GK
Publication Date: 2019-09

Variant appearance in text: IDH1: R132F
PubMed Link: 31300360
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mutation Analysis of Isocitrate Dehydrogenase (IDH1/2) and DNA Methyltransferase 3A (DNMT3A) in Thai Patients with Newly Diagnosed Acute Myeloid Leukemia

Asian Pacific Journal Of Cancer Prevention : Apjcp
Sirirat, Tanasan T; Chuncharunee, Suporn S; Nipaluk, Pimjai P; Siriboonpiputtana, Teerapong T; Chareonsirisuthigul, Takol T; Limsuwannachot, Nittaya N; Rerkamnuaychoke, Budsaba B
Publication Date: 2017-02-01

Variant appearance in text: IDH1: R132F
PubMed Link: 28345823
Variant Present in the following documents:
  • Main text
  • APJCP-18-413.pdf
View BVdb publication page



Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes.

Plos One
Jin, Yonghui Y; Elalaf, Hassan H; Watanabe, Makoto M; Tamaki, Sakura S; Hineno, Sho S; Matsunaga, Kazuhito K; Woltjen, Knut K; Kobayashi, Yukiko Y; Nagata, Sanae S; Ikeya, Makoto M; Kato, Tomohisa T; Okamoto, Takeshi T; Matsuda, Shuichi S; Toguchida, Junya J
Publication Date: 2015

Variant appearance in text: IDH1: R132F
PubMed Link: 26161668
Variant Present in the following documents:
  • Main text
  • pone.0131998.pdf
View BVdb publication page



Isocitrate dehydrogenase 2 mutation is a frequent event in osteosarcoma detected by a multi-specific monoclonal antibody MsMab-1.

Cancer Medicine
Liu, Xing X; Kato, Yukinari Y; Kaneko, Mika Kato MK; Sugawara, Masato M; Ogasawara, Satoshi S; Tsujimoto, Yuta Y; Naganuma, Yasushi Y; Yamakawa, Mitsunori M; Tsuchiya, Takashi T; Takagi, Michiaki M
Publication Date: 2013-12

Variant appearance in text: IDH1: R132F
PubMed Link: 24403254
Variant Present in the following documents:
  • Main text
  • cam40002-0803.pdf
View BVdb publication page