Exome sequencing of Finnish isolates enhances rare-variant association power.
Nature
AE Locke, KM Steinberg, CWK Chiang, SK Service, AS Havulinna, L Stell, M Pirinen, HJ Abel, CC Chiang, RS Fulton, AU Jackson, CJ Kang, KL Kanchi, DC Koboldt, DE Larson, J Nelson, TJ Nicholas, A Pietilä, V Ramensky, D Ray, LJ Scott, HM Stringham, J Vangipurapu, R Welch, P Yajnik, X Yin, JG Eriksson, M Ala-Korpela, MR Järvelin, M Männikkö, H Laivuori, , SK Dutcher, NO Stitziel, RK Wilson, IM Hall, C Sabatti, A Palotie, V Salomaa, M Laakso, S Ripatti, M Boehnke, NB Freimer
Multiple rare and common variants in APOB gene locus associated with oxidatively modified low-density lipoprotein levels.
Plos One
E Khlebus, V Kutsenko, A Meshkov, A Ershova, A Kiseleva, A Shevtsov, N Shcherbakova, A Zharikova, V Lankin, A Tikhaze, I Chazova, E Yarovaya, O Drapkina, S Boytsov
Publication Date: 2019
Variant appearance in text: APOB: Thr2515Thr; rs693
Lipid Transporter Activity-Related Genetic Polymorphisms Are Associated With Steroid-Induced Osteonecrosis of the Femoral Head: An Updated Meta-Analysis Based on the GRADE Guidelines.
Apolipoprotein B and angiotensin-converting enzyme polymorphisms and aerobic interval training: randomized controlled trial in coronary artery disease patients.
Brazilian Journal Of Medical And Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas
NY Tamburus, R Verlengia, VC Kunz, MC César, E Silva
Genome-wide admixture and association study of subclinical atherosclerosis in the Women's Interagency HIV Study (WIHS).
Plos One
A Shendre, HW Wiener, MR Irvin, BE Aouizerat, ET Overton, J Lazar, C Liu, HN Hodis, NA Limdi, KM Weber, SJ Gange, D Zhi, MA Floris-Moore, I Ofotokun, Q Qi, DB Hanna, RC Kaplan, S Shrestha
Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.
Plos Genetics
JP Davis, JR Huyghe, AE Locke, AU Jackson, X Sim, HM Stringham, TM Teslovich, RP Welch, C Fuchsberger, N Narisu, PS Chines, AJ Kangas, P Soininen, M Ala-Korpela, J Kuusisto, FS Collins, M Laakso, M Boehnke, KL Mohlke
GRECOS Project (Genotyping Recurrence Risk of Stroke): The Use of Genetics to Predict the Vascular Recurrence After Stroke.
Stroke
I Fernández-Cadenas, M Mendióroz, D Giralt, C Nafria, E Garcia, C Carrera, C Gallego-Fabrega, S Domingues-Montanari, P Delgado, M Ribó, M Castellanos, S Martínez, M Freijo, J Jiménez-Conde, M Rubiera, J Alvarez-Sabín, CA Molina, MA Font, M Grau Olivares, E Palomeras, N Perez de la Ossa, M Martinez-Zabaleta, J Masjuan, F Moniche, D Canovas, C Piñana, F Purroy, D Cocho, I Navas, C Tejero, N Aymerich, N Cullell, E Muiño, J Serena, F Rubio, A Davalos, J Roquer, JF Arenillas, J Martí-Fábregas, K Keene, WM Chen, B Worrall, M Sale, A Arboix, J Krupinski, J Montaner,
Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
Genome Medicine
R Nagy, TS Boutin, J Marten, JE Huffman, SM Kerr, A Campbell, L Evenden, J Gibson, C Amador, DM Howard, P Navarro, A Morris, IJ Deary, LJ Hocking, S Padmanabhan, BH Smith, P Joshi, JF Wilson, ND Hastie, AF Wright, AM McIntosh, DJ Porteous, CS Haley, V Vitart, C Hayward
Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits.
American Journal Of Human Genetics
M Civelek, Y Wu, C Pan, CK Raulerson, A Ko, A He, C Tilford, NK Saleem, A Stančáková, LJ Scott, C Fuchsberger, HM Stringham, AU Jackson, N Narisu, PS Chines, KS Small, J Kuusisto, BW Parks, P Pajukanta, T Kirchgessner, FS Collins, PS Gargalovic, M Boehnke, M Laakso, KL Mohlke, AJ Lusis
Harnessing publicly available genetic data to prioritize lipid modifying therapeutic targets for prevention of coronary heart disease based on dysglycemic risk.
Human Genetics
V Tragante, FW Asselbergs, DI Swerdlow, TM Palmer, JH Moore, PIW de Bakker, BJ Keating, MV Holmes
Privacy-preserving genomic testing in the clinic: a model using HIV treatment.
Genetics In Medicine : Official Journal Of The American College Of Medical Genetics
PJ McLaren, JL Raisaro, M Aouri, M Rotger, E Ayday, I Bartha, MB Delgado, Y Vallet, HF Günthard, M Cavassini, H Furrer, T Doco-Lecompte, C Marzolini, P Schmid, C Di Benedetto, LA Decosterd, J Fellay, JP Hubaux, A Telenti
Detection of pleiotropy through a Phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study.
Plos Genetics
MA Hall, A Verma, KD Brown-Gentry, R Goodloe, J Boston, S Wilson, B McClellan, C Sutcliffe, HH Dilks, NB Gillani, H Jin, P Mayo, M Allen, N Schnetz-Boutaud, DC Crawford, MD Ritchie, SA Pendergrass
The challenges of genome-wide interaction studies: lessons to learn from the analysis of HDL blood levels.
Plos One
EM van Leeuwen, FA Smouter, T Kam-Thong, N Karbalai, AV Smith, TB Harris, LJ Launer, CM Sitlani, G Li, JA Brody, JC Bis, CC White, A Jaiswal, BA Oostra, A Hofman, F Rivadeneira, AG Uitterlinden, E Boerwinkle, CM Ballantyne, V Gudnason, BM Psaty, LA Cupples, MR Järvelin, S Ripatti, A Isaacs, B Müller-Myhsok, LC Karssen, CM van Duijn
Identification of genes contributing to cardiovascular disease in overweight and obese individuals from West Virginia.
The West Virginia Medical Journal
Y Dementieva, TL Green, DA Primerano, L Wei, J Denvir, P Wehner, S Dodson, MR Flood, BA Pollock, M Huff, C Hill, R Kreisberg, A Francis, K Morrison, H Blackwood, M Davis, HM Lee, S Warren,
Multiancestral analysis of inflammation-related genetic variants and C-reactive protein in the population architecture using genomics and epidemiology study.
Circulation. Cardiovascular Genetics
JM Kocarnik, SA Pendergrass, CL Carty, JS Pankow, FR Schumacher, I Cheng, P Durda, JL Ambite, E Deelman, NR Cook, S Liu, J Wactawski-Wende, C Hutter, K Brown-Gentry, S Wilson, LG Best, N Pankratz, CP Hong, SA Cole, VS Voruganti, P Bůžkova, NW Jorgensen, NS Jenny, LR Wilkens, CA Haiman, LN Kolonel, A Lacroix, K North, R Jackson, L Le Marchand, LA Hindorff, DC Crawford, M Gross, U Peters
A genome wide association study identifies common variants associated with lipid levels in the Chinese population.
Plos One
L Zhou, M He, Z Mo, C Wu, H Yang, D Yu, X Yang, X Zhang, Y Wang, J Sun, Y Gao, A Tan, Y He, H Zhang, X Qin, J Zhu, H Li, X Lin, J Zhu, X Min, M Lang, D Li, K Zhai, J Chang, W Tan, J Yuan, W Chen, Y Wang, S Wei, X Miao, F Wang, W Fang, Y Liang, Q Deng, X Dai, D Lin, S Huang, H Guo, S Lilly Zheng, J Xu, D Lin, FB Hu, T Wu
Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data.
Nature Biotechnology
JC Denny, L Bastarache, MD Ritchie, RJ Carroll, R Zink, JD Mosley, JR Field, JM Pulley, AH Ramirez, E Bowton, MA Basford, DS Carrell, PL Peissig, AN Kho, JA Pacheco, LV Rasmussen, DR Crosslin, PK Crane, J Pathak, SJ Bielinski, SA Pendergrass, H Xu, LA Hindorff, R Li, TA Manolio, CG Chute, RL Chisholm, EB Larson, GP Jarvik, MH Brilliant, CA McCarty, IJ Kullo, JL Haines, DC Crawford, DR Masys, DM Roden
No evidence of interaction between known lipid-associated genetic variants and smoking in the multi-ethnic PAGE population.
Human Genetics
L Dumitrescu, CL Carty, N Franceschini, LA Hindorff, SA Cole, P Bůžková, FR Schumacher, CB Eaton, RJ Goodloe, DJ Duggan, J Haessler, B Cochran, BE Henderson, I Cheng, KC Johnson, CS Carlson, SA Love, K Brown-Gentry, AQ Nato, M Quibrera, RV Shohet, JL Ambite, LR Wilkens, L Le Marchand, CA Haiman, S Buyske, C Kooperberg, KE North, M Fornage, DC Crawford
Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study.
Plos Biology
CS Carlson, TC Matise, KE North, CA Haiman, MD Fesinmeyer, S Buyske, FR Schumacher, U Peters, N Franceschini, MD Ritchie, DJ Duggan, KL Spencer, L Dumitrescu, CB Eaton, F Thomas, A Young, C Carty, G Heiss, L Le Marchand, DC Crawford, LA Hindorff, CL Kooperberg,