Association between insulin receptor substrate-1 polymorphisms and high platelet reactivity with clopidogrel therapy in coronary artery disease patients with type 2 diabetes mellitus.
The Gly(972)Arg variant of human IRS1 gene is associated with variation in glomerular filtration rate likely through impaired insulin receptor signaling.
Diabetes
Thameem, Farook F; Puppala, Sobha S; Schneider, Jennifer J; Bhandari, Basant B; Arya, Rector R; Arar, Nedal H NH; Vasylyeva, Tetyana L TL; Farook, Vidya S VS; Fowler, Sharon S; Almasy, Laura L; Blangero, John J; Duggirala, Ravindranath R; Abboud, Hanna E HE