Publications:

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Current Studies on Molecular Mechanisms of Insulin Resistance.

Journal Of Diabetes Research

Pei, Jinli J; Wang, Baochun B; Wang, Dayong D

Publication Date: 2022

Variant appearance in text: IRS1: Ala512Pro

PubMed Link: 36589630

Variant Present in the following documents:

• JDR2022-1863429.pdf

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Integrated molecular profiling of patient-derived ovarian cancer models identifies clinically relevant signatures and tumor vulnerabilities.

International Journal Of Cancer

Lupia, Michela M; Melocchi, Valentina V; Bizzaro, Francesca F; Lo Riso, Pietro P; Dama, Elisa E; Baronio, Micol M; Ranghiero, Alberto A; Barberis, Massimo M; Bernard, Loris L; Bertalot, Giovanni G; Giavazzi, Raffaella R; Testa, Giuseppe G; Bianchi, Fabrizio F; Cavallaro, Ugo U

Publication Date: 2022-07-15

Variant appearance in text: IRS1: Ala512Pro; rs1801276

PubMed Link: 35218560

Variant Present in the following documents:

• IJC-151-240-s001.xlsx, sheet 7

View BVdb publication page

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Significant variants of type 2 diabetes in the Arabian Region through an Integration of exome databases.

Plos One

Goto, Kosuke K; Mineta, Katsuhiko K; Miyazaki, Satoru S; Gojobori, Takashi T

Publication Date: 2021

Variant appearance in text: IRS1: 1534G>C; Ala512Pro; rs1801276

PubMed Link: 33848288

Variant Present in the following documents:

• Main text
• pone.0249226.pdf

View BVdb publication page

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Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia.

Nature Communications

Kusakabe, Manabu M; Sun, Ann Chong AC; Tyshchenko, Kateryna K; Wong, Rachel R; Nanda, Aastha A; Shanna, Claire C; Gusscott, Samuel S; Chavez, Elizabeth A EA; Lorzadeh, Alireza A; Zhu, Alice A; Hill, Ainsleigh A; Hung, Stacy S; Brown, Scott S; Babaian, Artem A; Wang, Xuehai X; Holt, Robert A RA; Steidl, Christian C; Karsan, Aly A; Humphries, R Keith RK; Eaves, Connie J CJ; Hirst, Martin M; Weng, Andrew P AP

Publication Date: 2019-07-02

Variant appearance in text: IRS1: 1534G>C; Ala512Pro; rs1801276

PubMed Link: 31266935

Variant Present in the following documents:

• 41467_2019_10510_MOESM8_ESM.xlsx, sheet 3
• 41467_2019_10510_MOESM8_ESM.xlsx, sheet 1
• 41467_2019_10510_MOESM8_ESM.xlsx, sheet 2

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A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.

Scientific Reports

Stringer, Brett W BW; Day, Bryan W BW; D'Souza, Rochelle C J RCJ; Jamieson, Paul R PR; Ensbey, Kathleen S KS; Bruce, Zara C ZC; Lim, Yi Chieh YC; Goasdoué, Kate K; Offenhäuser, Carolin C; Akgül, Seçkin S; Allan, Suzanne S; Robertson, Thomas T; Lucas, Peter P; Tollesson, Gert G; Campbell, Scott S; Winter, Craig C; Do, Hongdo H; Dobrovic, Alexander A; Inglis, Po-Ling PL; Jeffree, Rosalind L RL; Johns, Terrance G TG; Boyd, Andrew W AW

Publication Date: 2019-03-20

Variant appearance in text: IRS1: A512P; rs1801276

PubMed Link: 30894629

Variant Present in the following documents:

• 41598_2019_41277_MOESM4_ESM.xlsx, sheet 13

View BVdb publication page

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Genetic Variants in Preeclampsia: Lessons From Studies in Latin-American Populations.

Frontiers In Physiology

Michita, Rafael Tomoya RT; Kaminski, Valéria de Lima VL; Chies, José Artur Bogo JAB

Publication Date: 2018

Variant appearance in text: rs1801276

PubMed Link: 30618791

Variant Present in the following documents:

• Main text
• fphys-09-01771.pdf

View BVdb publication page

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TRPV4 and KRAS and FGFR1 gain-of-function mutations drive giant cell lesions of the jaw.

Nature Communications

Gomes, Carolina Cavalieri CC; Gayden, Tenzin T; Bajic, Andrea A; Harraz, Osama F OF; Pratt, Jonathan J; Nikbakht, Hamid H; Bareke, Eric E; Diniz, Marina Gonçalves MG; Castro, Wagner Henriques WH; St-Onge, Pascal P; Sinnett, Daniel D; Han, HyeRim H; Rivera, Barbara B; Mikael, Leonie G LG; De Jay, Nicolas N; Kleinman, Claudia L CL; Valera, Elvis Terci ET; Bassenden, Angelia V AV; Berghuis, Albert M AM; Majewski, Jacek J; Nelson, Mark T MT; Gomez, Ricardo Santiago RS; Jabado, Nada N

Publication Date: 2018-11-01

Variant appearance in text: IRS1: A512P; rs1801276

PubMed Link: 30385747

Variant Present in the following documents:

• 41467_2018_6690_MOESM8_ESM.xlsx, sheet 1

View BVdb publication page

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Genetic Epidemiology of Type 2 Diabetes in Mexican Mestizos.

Biomed Research International

García-Chapa, Eiralí Guadalupe EG; Leal-Ugarte, Evelia E; Peralta-Leal, Valeria V; Durán-González, Jorge J; Meza-Espinoza, Juan Pablo JP

Publication Date: 2017

Variant appearance in text: rs1801276

PubMed Link: 28607931

Variant Present in the following documents:

• Main text
• BMRI2017-3937893.pdf

View BVdb publication page

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Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model.

The Journal Of Pathology

Maguire, Sarah L SL; Peck, Barrie B; Wai, Patty T PT; Campbell, James J; Barker, Holly H; Gulati, Aditi A; Daley, Frances F; Vyse, Simon S; Huang, Paul P; Lord, Christopher J CJ; Farnie, Gillian G; Brennan, Keith K; Natrajan, Rachael R

Publication Date: 2016-11

Variant appearance in text: IRS1: A512P; rs1801276

PubMed Link: 27512948

Variant Present in the following documents:

• PATH-240-315-s015.xlsx, sheet 1

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Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response.

Oncogene

Nickerson, M L ML; Witte, N N; Im, K M KM; Turan, S S; Owens, C C; Misner, K K; Tsang, S X SX; Cai, Z Z; Wu, S S; Dean, M M; Costello, J C JC; Theodorescu, D D

Publication Date: 2017-01-05

Variant appearance in text: IRS1: A512P; rs1801276

PubMed Link: 27270441

Variant Present in the following documents:

• onc2016172x3.xls, sheet 3

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Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Plos One

Holehouse, Alex S AS; Naegle, Kristen M KM

Publication Date: 2015

Variant appearance in text: rs1801276

PubMed Link: 26659599

Variant Present in the following documents:

• pone.0144692.s002.xlsx, sheet 1

View BVdb publication page

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GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics

Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J

Publication Date: 2015-07-25

Variant appearance in text: IRS1: A512P

PubMed Link: 26206375

Variant Present in the following documents:

• 12859_2015_673_MOESM1_ESM.xls, sheet 3

View BVdb publication page

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Associations of Haplotypes Upstream of IRS1 with Insulin Resistance, Type 2 Diabetes, Dyslipidemia, Preclinical Atherosclerosis, and Skeletal Muscle LOC646736 mRNA Levels.

Journal Of Diabetes Research

Soyal, Selma M SM; Felder, Thomas T; Auer, Simon S; Oberkofler, Hannes H; Iglseder, Bernhard B; Paulweber, Bernhard B; Dossena, Silvia S; Nofziger, Charity C; Paulmichl, Markus M; Esterbauer, Harald H; Krempler, Franz F; Patsch, Wolfgang W

Publication Date: 2015

Variant appearance in text: rs1801276

PubMed Link: 26090471

Variant Present in the following documents:

• Main text

View BVdb publication page

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A rare co-segregation-mutation in the insulin receptor substrate 1 gene in one Chinese family with ankylosing spondylitis.

Plos One

Rong, Ju J; Li, Qiuxia Q; Zhang, Pingping P; Wu, Xinyu X; Huang, Jinxian J; Li, Chao C; Liao, Zetao Z; Xie, Yingying Y; Lv, Qing Q; Wei, Qiujing Q; Li, Tianwang T; Huang, Jianlin J; Cao, Shuangyan S; Shen, Yan Y; Gu, Jieruo J

Publication Date: 2015

Variant appearance in text: IRS1: Ala512Pro

PubMed Link: 25978640

Variant Present in the following documents:

• Main text

View BVdb publication page

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Exome sequencing of case-unaffected-parents trios reveals recessive and de novo genetic variants in sporadic ALS.

Scientific Reports

Steinberg, Karyn Meltz KM; Yu, Bing B; Koboldt, Daniel C DC; Mardis, Elaine R ER; Pamphlett, Roger R

Publication Date: 2015-03-16

Variant appearance in text: IRS1: A512P; rs1801276

PubMed Link: 25773295

Variant Present in the following documents:

• srep09124-s3.xls, sheet 1

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IRS1 gene polymorphisms Gly972Arg and Ala513Pro are not associated with insulin resistance and type 2 diabetes risk in non-obese Turkish population.

Meta Gene

Arikoglu, Hilal H; Aksoy Hepdogru, Melda M; Erkoc Kaya, Dudu D; Asik, Aycan A; Ipekci, Suleyman Hilmi SH; Iscioglu, Funda F

Publication Date: 2014-12

Variant appearance in text: rs1801276

PubMed Link: 25606440

Variant Present in the following documents:

• Main text
• main.pdf

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Insulin-like growth factor axis gene polymorphisms and clinical outcomes in pancreatic cancer.

Gastroenterology

Dong, Xiaoqun X; Javle, Milind M; Hess, Kenneth R KR; Shroff, Rachna R; Abbruzzese, James L JL; Li, Donghui D

Publication Date: 2010-08

Variant appearance in text: IRS1: A512P

PubMed Link: 20416304

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetic variation in candidate obesity genes ADRB2, ADRB3, GHRL, HSD11B1, IRS1, IRS2, and SHC1 and risk for breast cancer in the Cancer Prevention Study II.

Breast Cancer Research : Bcr

Feigelson, Heather Spencer HS; Teras, Lauren R LR; Diver, W Ryan WR; Tang, Weining W; Patel, Alpa V AV; Stevens, Victoria L VL; Calle, Eugenia E EE; Thun, Michael J MJ; Bouzyk, Mark M

Publication Date: 2008

Variant appearance in text: rs1801276

PubMed Link: 18611262

Variant Present in the following documents:

• Main text
• bcr2114.pdf

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