Intravesical BCG in patients with non-muscle invasive bladder cancer induces trained immunity and decreases respiratory infections.
Journal For Immunotherapy Of Cancer
van Puffelen, Jelmer H JH; Novakovic, Boris B; van Emst, Liesbeth L; Kooper, Denise D; Zuiverloon, Tahlita C M TCM; Oldenhof, Ursula T H UTH; Witjes, J Alfred JA; Galesloot, Tessel E TE; Vrieling, Alina A; Aben, Katja K H KKH; Kiemeney, Lambertus A L M LALM; Oosterwijk, Egbert E; Netea, Mihai G MG; Boormans, Joost L JL; van der Heijden, Antoine G AG; Joosten, Leo A B LAB; Vermeulen, Sita H SH
Population-Wide Genetic Risk Prediction of Complex Diseases: A Pilot Feasibility Study in Macau Population for Precision Public Healthcare Planning.
Scientific Reports
Tsui, Nancy B Y NBY; Cheng, Gregory G; Chung, Teresa T; Lam, Christopher W K CWK; Yee, Anita A; Chung, Peter K C PKC; Kwan, Tsz-Ki TK; Ko, Elaine E; He, Daihai D; Wong, Wing-Tak WT; Lau, Johnson Y N JYN; Lau, Lok Ting LT; Fok, Manson M
Fine-mapping inflammatory bowel disease loci to single-variant resolution.
Nature
Huang, Hailiang H; Fang, Ming M; Jostins, Luke L; Umićević Mirkov, Maša M; Boucher, Gabrielle G; Anderson, Carl A CA; Andersen, Vibeke V; Cleynen, Isabelle I; Cortes, Adrian A; Crins, François F; D'Amato, Mauro M; Deffontaine, Valérie V; Dmitrieva, Julia J; Docampo, Elisa E; Elansary, Mahmoud M; Farh, Kyle Kai-How KK; Franke, Andre A; Gori, Ann-Stephan AS; Goyette, Philippe P; Halfvarson, Jonas J; Haritunians, Talin T; Knight, Jo J; Lawrance, Ian C IC; Lees, Charlie W CW; Louis, Edouard E; Mariman, Rob R; Meuwissen, Theo T; Mni, Myriam M; Momozawa, Yukihide Y; Parkes, Miles M; Spain, Sarah L SL; Théâtre, Emilie E; Trynka, Gosia G; Satsangi, Jack J; van Sommeren, Suzanne S; Vermeire, Severine S; Xavier, Ramnik J RJ; , ; Weersma, Rinse K RK; Duerr, Richard H RH; Mathew, Christopher G CG; Rioux, John D JD; McGovern, Dermot P B DPB; Cho, Judy H JH; Georges, Michel M; Daly, Mark J MJ; Barrett, Jeffrey C JC
PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites.
Plos One
Glas, Jürgen J; Seiderer, Julia J; Czamara, Darina D; Pasciuto, Giulia G; Diegelmann, Julia J; Wetzke, Martin M; Olszak, Torsten T; Wolf, Christiane C; Müller-Myhsok, Bertram B; Balschun, Tobias T; Achkar, Jean-Paul JP; Kamboh, M Ilyas MI; Franke, Andre A; Duerr, Richard H RH; Brand, Stephan S
Investigation of genetic risk factors for chronic adult diseases for association with preterm birth.
Human Genetics
Falah, Nadia N; McElroy, Jude J; Snegovskikh, Victoria V; Lockwood, Charles J CJ; Norwitz, Errol E; Murray, Jeffey C JC; Kuczynski, Edward E; Menon, Ramkumar R; Teramo, Kari K; Muglia, Louis J LJ; Morgan, Thomas T
Prevalence of genetic variants associated with inflammatory bowel disease in a healthy First Nations cohort.
Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne
Murdoch, Travis B TB; Bernstein, Charles N CN; El-Gabalawy, Hani H; Stempak, Joanne M JM; Sargent, Michael M; Elias, Brenda B; Xu, Wei W; Pathan, Saad S; Silverberg, Mark S MS
Distinct and overlapping genetic loci in Crohn's disease and ulcerative colitis: correlations with pathogenesis.
Inflammatory Bowel Diseases
Waterman, Matti M; Xu, Wei W; Stempak, Joanne M JM; Milgrom, Raquel R; Bernstein, Charles N CN; Griffiths, Anne M AM; Greenberg, Gordon R GR; Steinhart, A Hillary AH; Silverberg, Mark S MS
Replication and meta-analysis of 13,000 cases defines the risk for interleukin-23 receptor and autophagy-related 16-like 1 variants in Crohn's disease.
Canadian Journal Of Gastroenterology = Journal Canadien De Gastroenterologie
Cotterill, Lynn L; Payne, Debbie D; Levinson, Scott S; McLaughlin, John J; Wesley, Emma E; Feeney, Mark M; Durbin, Hilary H; Lal, Simon S; Makin, Alistair A; Campbell, Simon S; Roberts, Stephen A SA; O'Neill, Catherine C; Edwards, Cathryn C; Newman, William G WG
Genome-wide association identifies multiple ulcerative colitis susceptibility loci.
Nature Genetics
McGovern, Dermot P B DP; Gardet, Agnès A; Törkvist, Leif L; Goyette, Philippe P; Essers, Jonah J; Taylor, Kent D KD; Neale, Benjamin M BM; Ong, Rick T H RT; Lagacé, Caroline C; Li, Chun C; Green, Todd T; Stevens, Christine R CR; Beauchamp, Claudine C; Fleshner, Phillip R PR; Carlson, Marie M; D'Amato, Mauro M; Halfvarson, Jonas J; Hibberd, Martin L ML; Lördal, Mikael M; Padyukov, Leonid L; Andriulli, Angelo A; Colombo, Elisabetta E; Latiano, Anna A; Palmieri, Orazio O; Bernard, Edmond-Jean EJ; Deslandres, Colette C; Hommes, Daan W DW; de Jong, Dirk J DJ; Stokkers, Pieter C PC; Weersma, Rinse K RK; , ; Sharma, Yashoda Y; Silverberg, Mark S MS; Cho, Judy H JH; Wu, Jing J; Roeder, Kathryn K; Brant, Steven R SR; Schumm, L Phillip LP; Duerr, Richard H RH; Dubinsky, Marla C MC; Glazer, Nicole L NL; Haritunians, Talin T; Ippoliti, Andy A; Melmed, Gil Y GY; Siscovick, David S DS; Vasiliauskas, Eric A EA; Targan, Stephan R SR; Annese, Vito V; Wijmenga, Cisca C; Pettersson, Sven S; Rotter, Jerome I JI; Xavier, Ramnik J RJ; Daly, Mark J MJ; Rioux, John D JD; Seielstad, Mark M
Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.
Plos Genetics
Raychaudhuri, Soumya S; Plenge, Robert M RM; Rossin, Elizabeth J EJ; Ng, Aylwin C Y AC; , ; Purcell, Shaun M SM; Sklar, Pamela P; Scolnick, Edward M EM; Xavier, Ramnik J RJ; Altshuler, David D; Daly, Mark J MJ
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
Nature Genetics
Barrett, Jeffrey C JC; Hansoul, Sarah S; Nicolae, Dan L DL; Cho, Judy H JH; Duerr, Richard H RH; Rioux, John D JD; Brant, Steven R SR; Silverberg, Mark S MS; Taylor, Kent D KD; Barmada, M Michael MM; Bitton, Alain A; Dassopoulos, Themistocles T; Datta, Lisa Wu LW; Green, Todd T; Griffiths, Anne M AM; Kistner, Emily O EO; Murtha, Michael T MT; Regueiro, Miguel D MD; Rotter, Jerome I JI; Schumm, L Philip LP; Steinhart, A Hillary AH; Targan, Stephan R SR; Xavier, Ramnik J RJ; , ; Libioulle, Cécile C; Sandor, Cynthia C; Lathrop, Mark M; Belaiche, Jacques J; Dewit, Olivier O; Gut, Ivo I; Heath, Simon S; Laukens, Debby D; Mni, Myriam M; Rutgeerts, Paul P; Van Gossum, André A; Zelenika, Diana D; Franchimont, Denis D; Hugot, Jean-Pierre JP; de Vos, Martine M; Vermeire, Severine S; Louis, Edouard E; , ; , ; Cardon, Lon R LR; Anderson, Carl A CA; Drummond, Hazel H; Nimmo, Elaine E; Ahmad, Tariq T; Prescott, Natalie J NJ; Onnie, Clive M CM; Fisher, Sheila A SA; Marchini, Jonathan J; Ghori, Jilur J; Bumpstead, Suzannah S; Gwilliam, Rhian R; Tremelling, Mark M; Deloukas, Panos P; Mansfield, John J; Jewell, Derek D; Satsangi, Jack J; Mathew, Christopher G CG; Parkes, Miles M; Georges, Michel M; Daly, Mark J MJ