A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Jang, H Josh HJ; Hostetter, Galen G; MacFarlane, Alexander W AW; Madaj, Zachary Z; Ross, Eric A EA; Hinoue, Toshinori T; Kulchycki, Justin R JR; Burgos, Ryan S RS; Tafseer, Mahvish M; Alpaugh, R Katherine RK; Schwebel, Candice L CL; Kokate, Rutika R; Geynisman, Daniel M DM; Zibelman, Matthew R MR; Ghatalia, Pooja P; Nichols, Peter W PW; Chung, Woonbok W; Madzo, Jozef J; Hahn, Noah M NM; Quinn, David I DI; Issa, Jean-Pierre J JJ; Topper, Michael J MJ; Baylin, Stephen B SB; Shen, Hui H; Campbell, Kerry S KS; Jones, Peter A PA; Plimack, Elizabeth R ER
Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Advanced bioinformatic analysis and pathway prediction of NSCLC cells upon cisplatin resistance.
Scientific Reports
Hossian, A K M Nawshad AKMN; Zahra, Fatema Tuz FT; Poudel, Sagun S; Abshire, Camille F CF; Polk, Paula P; Garai, Jone J; Zabaleta, Jovanny J; Mikelis, Constantinos M CM; Mattheolabakis, George G
Publication Date: 2021-03-22
Variant appearance in text: EFR3B: 2421T>C; Tyr807Tyr
Integrated genetic and metabolic landscapes predict vulnerabilities of temozolomide resistant glioblastoma cells.
Npj Systems Biology And Applications
Immanuel, Selva Rupa Christinal SRC; Ghanate, Avinash D AD; Parmar, Dharmeshkumar S DS; Yadav, Ritu R; Uthup, Riya R; Panchagnula, Venkateswarlu V; Raghunathan, Anu A
Publication Date: 2021-01-08
Variant appearance in text: EFR3B: 2421T>C; Y807Y; rs2164808
Multi-level evidence of an allelic hierarchy of USH2A variants in hearing, auditory processing and speech/language outcomes.
Communications Biology
Perrino, Peter A PA; Talbot, Lidiya L; Kirkland, Rose R; Hill, Amanda A; Rendall, Amanda R AR; Mountford, Hayley S HS; Taylor, Jenny J; , ; Buscarello, Alexzandrea N AN; Lahiri, Nayana N; Saggar, Anand A; Fitch, R Holly RH; Newbury, Dianne F DF
Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines.
Scientific Reports
Skowron, Margaretha A MA; Petzsch, Patrick P; Hardt, Karin K; Wagner, Nicholas N; Beier, Manfred M; Stepanow, Stefanie S; Drechsler, Matthias M; Rieder, Harald H; Köhrer, Karl K; Niegisch, Günter G; Hoffmann, Michèle J MJ; Schulz, Wolfgang A WA
Publication Date: 2019-10-09
Variant appearance in text: EFR3B: Y807Y; rs2164808
Sharma, Yogita Y; Miladi, Milad M; Dukare, Sandeep S; Boulay, Karine K; Caudron-Herger, Maiwen M; Groß, Matthias M; Backofen, Rolf R; Diederichs, Sven S
Whole-exome sequencing of over 4100 men of African ancestry and prostate cancer risk.
Human Molecular Genetics
Rand, Kristin A KA; Rohland, Nadin N; Tandon, Arti A; Stram, Alex A; Sheng, Xin X; Do, Ron R; Pasaniuc, Bogdan B; Allen, Alex A; Quinque, Dominique D; Mallick, Swapan S; Le Marchand, Loic L; Kaggwa, Sam S; Lubwama, Alex A; , ; , ; Stram, Daniel O DO; Watya, Stephen S; Henderson, Brian E BE; Conti, David V DV; Reich, David D; Haiman, Christopher A CA
Publication Date: 2016-01-15
Variant appearance in text: EFR3B: Tyr807Tyr; rs2164808
Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells.
Stem Cell Reports
Garate, Zita Z; Quintana-Bustamante, Oscar O; Crane, Ana M AM; Olivier, Emmanuel E; Poirot, Laurent L; Galetto, Roman R; Kosinski, Penelope P; Hill, Collin C; Kung, Charles C; Agirre, Xabi X; Orman, Israel I; Cerrato, Laura L; Alberquilla, Omaira O; Rodriguez-Fornes, Fatima F; Fusaki, Noemi N; Garcia-Sanchez, Felix F; Maia, Tabita M TM; Ribeiro, Maria L ML; Sevilla, Julian J; Prosper, Felipe F; Jin, Shengfang S; Mountford, Joanne J; Guenechea, Guillermo G; Gouble, Agnes A; Bueren, Juan A JA; Davis, Brian R BR; Segovia, Jose C JC
Publication Date: 2015-12-08
Variant appearance in text: EFR3B: Y807Y; rs2164808
Whole-genome sequencing of the world's oldest people.
Plos One
Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK
Publication Date: 2014
Variant appearance in text: EFR3B: Y807Y; rs2164808
A large-scale candidate gene association study of age at menarche and age at natural menopause.
Human Genetics
He, Chunyan C; Kraft, Peter P; Chasman, Daniel I DI; Buring, Julie E JE; Chen, Constance C; Hankinson, Susan E SE; Paré, Guillaume G; Chanock, Stephen S; Ridker, Paul M PM; Hunter, David J DJ
Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium.
Human Molecular Genetics
Canzian, Federico F; Cox, David G DG; Setiawan, V Wendy VW; Stram, Daniel O DO; Ziegler, Regina G RG; Dossus, Laure L; Beckmann, Lars L; Blanché, Hélène H; Barricarte, Aurelio A; Berg, Christine D CD; Bingham, Sheila S; Buring, Julie J; Buys, Saundra S SS; Calle, Eugenia E EE; Chanock, Stephen J SJ; Clavel-Chapelon, Françoise F; DeLancey, John Oliver L JO; Diver, W Ryan WR; Dorronsoro, Miren M; Haiman, Christopher A CA; Hallmans, Göran G; Hankinson, Susan E SE; Hunter, David J DJ; Hüsing, Anika A; Isaacs, Claudine C; Khaw, Kay-Tee KT; Kolonel, Laurence N LN; Kraft, Peter P; Le Marchand, Loïc L; Lund, Eiliv E; Overvad, Kim K; Panico, Salvatore S; Peeters, Petra H M PH; Pollak, Michael M; Thun, Michael J MJ; Tjønneland, Anne A; Trichopoulos, Dimitrios D; Tumino, Rosario R; Yeager, Meredith M; Hoover, Robert N RN; Riboli, Elio E; Thomas, Gilles G; Henderson, Brian E BE; Kaaks, Rudolf R; Feigelson, Heather Spencer HS
The opioid peptides enkephalin and beta-endorphin in alcohol dependence.
Biological Psychiatry
Racz, Ildiko I; Schürmann, Britta B; Karpushova, Anna A; Reuter, Martin M; Cichon, Sven S; Montag, Christian C; Fürst, Robert R; Schütz, Christian C; Franke, Petra E PE; Strohmaier, Jana J; Wienker, Thomas F TF; Terenius, Lars L; Osby, Urban U; Gunnar, Agneta A; Maier, Wolfgang W; Bilkei-Gorzó, Andras A; Nöthen, Markus M; Zimmer, Andreas A