Publications:

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From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia.

Nature Communications

Saez-Ayala, Magali M; Hoffer, Laurent L; Abel, Sébastien S; Ben Yaala, Khaoula K; Sicard, Benoit B; Andrieu, Guillaume P GP; Latiri, Mehdi M; Davison, Emma K EK; Ciufolini, Marco A MA; Brémond, Paul P; Rebuffet, Etienne E; Roche, Philippe P; Derviaux, Carine C; Voisset, Edwige E; Montersino, Camille C; Castellano, Remy R; Collette, Yves Y; Asnafi, Vahid V; Betzi, Stéphane S; Dubreuil, Patrice P; Combes, Sébastien S; Morelli, Xavier X

Publication Date: 2023-05-29

Variant appearance in text: DNMT3A: R882H

PubMed Link: 37248212

Variant Present in the following documents:

• 41467_2023_38668_MOESM1_ESM.pdf

View BVdb publication page

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Reprogramming of Acute Myeloid Leukemia Patients Cells: Harboring Cancer Mutations Requires Targeting of AML Hierarchy.

Stem Cells Translational Medicine

Golubeva, Diana D; Porras, Deanna P DP; Doyle, Meaghan M; Reid, Jennifer C JC; Tanasijevic, Borko B; Boyd, Allison L AL; Vojnits, Kinga K; Elrafie, Amro A; Qiao, Amy A; Bhatia, Mickie M

Publication Date: 2023-05-24

Variant appearance in text: DNMT3A: 2645G>A; Arg882His

PubMed Link: 37226319

Variant Present in the following documents:

• szad022.pdf

View BVdb publication page

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Evolution of age-related mutation-driven clonal haematopoiesis over 20 years is associated with metabolic dysfunction in obesity.

Ebiomedicine

Andersson-Assarsson, Johanna C JC; van Deuren, Rosanne C RC; Kristensson, Felipe M FM; Steehouwer, Marloes M; Sjöholm, Kajsa K; Svensson, Per-Arne PA; Pieterse, Marc M; Gilissen, Christian C; Taube, Magdalena M; Jacobson, Peter P; Perkins, Rosie R; Brunner, Han G HG; Netea, Mihai G MG; Peltonen, Markku M; Carlsson, Björn B; Hoischen, Alexander A; Carlsson, Lena M S LMS

Publication Date: 2023-05-18

Variant appearance in text: DNMT3A: 2645G>A; Arg882His

PubMed Link: 37209535

Variant Present in the following documents:

• Main text
• main.pdf
• mmc1.pdf

View BVdb publication page

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Precise diagnosis and targeted therapy of nodal T-follicular helper cell lymphoma (T-FHCL).

Frontiers In Oncology

Du, Jun J; Jin, Shikai S; Zhang, Minghui M; Fu, Xuehang X; Yang, Jingwen J; Zhang, Liwen L; Chen, Zhenwei Z; Huang, Zoufang Z; Li, Weisong W; Hou, Jian J; Wang, Ting T

Publication Date: 2023

Variant appearance in text: DNMT3A: R882H

PubMed Link: 37188182

Variant Present in the following documents:

• Main text
• fonc-13-1163190.pdf

View BVdb publication page

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Demethylating therapy increases cytotoxicity of CD44v6 CAR-T cells against acute myeloid leukemia.

Frontiers In Immunology

Tang, Ling L; Kong, Yingjie Y; Wang, Haobing H; Zou, Ping P; Sun, Ting T; Liu, Ying Y; Zhang, Juan J; Jin, Na N; Mao, Hanwen H; Zhu, Xiaojian X; Wang, Jue J; Meng, Fankai F; You, Yong Y

Publication Date: 2023

Variant appearance in text: DNMT3A: R882H

PubMed Link: 37180104

Variant Present in the following documents:

• Main text
• fimmu-14-1145441.pdf

View BVdb publication page

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Clonal cytopenia of undetermined significance (CCUS)-associated reversion of donor-derived, transient αβ T-cell large granular clonal lymphocytosis, emerging post-transplant in a patient with a history of γδ T-cell large granular lymphocytic leukemia.

Cold Spring Harbor Molecular Case Studies

El Hussein, Siba S; Evans, Andrew G AG; Fitzsimmons, John M JM; Leong, Nufatt N; Buldo, Meghan M; Segal, Jeremy P JP; Jajosky, Audrey N AN; Rothberg, Paul G PG; Liesveld, Jane L JL; Oltvai, Zoltán N ZN

Publication Date: 2023-04

Variant appearance in text: DNMT3A: 2645G>A; R882H

PubMed Link: 37160316

Variant Present in the following documents:

• Main text
• MCS006241Elh.pdf

View BVdb publication page

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Dynamics of Sequence and Structural Cell-Free DNA Landscapes in Small-Cell Lung Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Sivapalan, Lavanya L; Iams, Wade T WT; Belcaid, Zineb Z; Scott, Susan C SC; Niknafs, Noushin N; Balan, Archana A; White, James R JR; Kopparapu, Prasad P; Cann, Christopher C; Landon, Blair V BV; Pereira, Gavin G; Velculescu, Victor E VE; Hann, Christine L CL; Lovly, Christine M CM; Anagnostou, Valsamo V

Publication Date: 2023-04-18

Variant appearance in text: DNMT3A: R882H

PubMed Link: 37071497

Variant Present in the following documents:

• ccr-22-2242_ts1-9_suppts1-9.xlsx, sheet 6

View BVdb publication page

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Inflammatory signals from fatty bone marrow support DNMT3A driven clonal hematopoiesis.

Nature Communications

Zioni, N N; Bercovich, A Akhiad AA; Chapal-Ilani, N N; Bacharach, Tal T; Rappoport, N N; Solomon, A A; Avraham, R R; Kopitman, E E; Porat, Z Z; Sacma, M M; Hartmut, G G; Scheller, M M; Muller-Tidow, C C; Lipka, D D; Shlush, E E; Minden, M M; Kaushansky, N N; Shlush, Liran I LI

Publication Date: 2023-04-12

Variant appearance in text: DNMT3A: R882H

PubMed Link: 37045808

Variant Present in the following documents:

• Main text
• 41467_2023_Article_36906.pdf
• 41467_2023_36906_MOESM2_ESM.pdf

View BVdb publication page

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Efficient reconstruction of cell lineage trees for cell ancestry and cancer.

Nucleic Acids Research

Jang, Yeongjun Y; Fasching, Liana L; Bae, Taejeong T; Tomasini, Livia L; Schreiner, Jeremy J; Szekely, Anna A; Fernandez, Thomas V TV; Leckman, James F JF; Vaccarino, Flora M FM; Abyzov, Alexej A

Publication Date: 2023-04-07

Variant appearance in text: DNMT3A: R882H

PubMed Link: 37026484

Variant Present in the following documents:

• Main text
• gkad254.pdf

View BVdb publication page

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Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications

Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA

Publication Date: 2023-04-03

Variant appearance in text: DNMT3A: R882H

PubMed Link: 37012232

Variant Present in the following documents:

• 41467_2023_37547_MOESM10_ESM.xlsx, sheet 4
• 41467_2023_37547_MOESM10_ESM.xlsx, sheet 3
• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2

View BVdb publication page

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Unveiling the methyl transfer mechanisms in the epigenetic machinery DNMT3A-3 L: A comprehensive study integrating assembly dynamics with catalytic reactions.

Computational And Structural Biotechnology Journal

Yang, Wei W; Zhuang, Jingyuan J; Li, Chen C; Cheng, Gui-Juan GJ

Publication Date: 2023

Variant appearance in text: DNMT3A: Arg882His

PubMed Link: 36968013

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Preclinical development and evaluation of nanobody-based CD70-specific CAR T cells for the treatment of acute myeloid leukemia.

Cancer Immunology, Immunotherapy : Cii

Cheng, Jiali J; Ge, Tong T; Zhu, Xiaojian X; Wang, Jue J; Zeng, Yuhao Y; Mu, Wei W; Cai, Haodong H; Dai, Zhenyu Z; Jin, Jin J; Yang, Yongkun Y; Hu, Guang G; Mao, Xia X; Zhou, Jianfeng J; Zhu, Li L; Huang, Liang L

Publication Date: 2023-03-17

Variant appearance in text: DNMT3A: R882H

PubMed Link: 36932256

Variant Present in the following documents:

• 262_2023_3422_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Hereditary predisposition to malignant myeloid hemopathies: Caution in use of saliva and guideline based on our experience.

Frontiers In Oncology

Perani, Alexandre A; Bourthoumieu, Sylvie S; Rizzo, David D; Chauzeix, Jasmine J; Dauriat, Benjamin B; Turlure, Pascal P; Girault, Stéphane S; Veyrune, Léa L; Roubinet, Maxime M; Feuillard, Jean J; Yardin, Catherine C; Gachard, Nathalie N

Publication Date: 2023

Variant appearance in text: DNMT3A: R882H

PubMed Link: 36923434

Variant Present in the following documents:

• Main text
• fonc-13-1120829.pdf

View BVdb publication page

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Distinct disease mutations in DNMT3A result in a spectrum of behavioral, epigenetic, and transcriptional deficits.

Biorxiv : The Preprint Server For Biology

Beard, Diana C DC; Zhang, Xiyun X; Wu, Dennis Y DY; Martin, Jenna R JR; Hamagami, Nicole N; Swift, Raylynn G RG; McCullough, Katherine B KB; Ge, Xia X; Bell-Hensley, Austin A; Zheng, Hongjun H; Lawrence, Austin B AB; Hill, Cheryl A CA; Papouin, Thomas T; McAlinden, Audrey A; Garbow, Joel R JR; Dougherty, Joseph D JD; Maloney, Susan E SE; Gabel, Harrison W HW

Publication Date: 2023-02-27

Variant appearance in text: DNMT3A: R882H

PubMed Link: 36909558

Variant Present in the following documents:

• Main text
• nihpp-2023.02.27.530041v1.pdf

View BVdb publication page

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Identification of potential ferroptosis hub genes in acute-on-chronic liver failure based on bioinformatics analysis and experimental verification.

Bmc Medical Genomics

Kuang, Meixia M; Cai, Longhui L; Zhao, Jing J; Huang, Liqiao L; Ji, Yichun Y; Lv, Bingyao B; Kuang, Weihong W

Publication Date: 2023-03-11

Variant appearance in text: DNMT3A: R882H

PubMed Link: 36906552

Variant Present in the following documents:

• 12920_2023_Article_1480.pdf

View BVdb publication page

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Longitudinal single-cell profiling of chemotherapy response in acute myeloid leukemia.

Nature Communications

Naldini, Matteo Maria MM; Casirati, Gabriele G; Barcella, Matteo M; Rancoita, Paola Maria Vittoria PMV; Cosentino, Andrea A; Caserta, Carolina C; Pavesi, Francesca F; Zonari, Erika E; Desantis, Giacomo G; Gilioli, Diego D; Carrabba, Matteo Giovanni MG; Vago, Luca L; Bernardi, Massimo M; Di Micco, Raffaella R; Di Serio, Clelia C; Merelli, Ivan I; Volpin, Monica M; Montini, Eugenio E; Ciceri, Fabio F; Gentner, Bernhard B

Publication Date: 2023-03-08

Variant appearance in text: DNMT3A: R882H

PubMed Link: 36890137

Variant Present in the following documents:

• 41467_2023_36969_MOESM1_ESM.pdf

View BVdb publication page

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Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery

Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI

Publication Date: 2023-03-02

Variant appearance in text: DNMT3A: R882H

PubMed Link: 36862804

Variant Present in the following documents:

• cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 5

View BVdb publication page

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Epigenetic Regulations in Mammalian Cells: Roles and Profiling Techniques.

Molecules And Cells

Kim, Uijin U; Lee, Dong-Sung DS

Publication Date: 2023-02-28

Variant appearance in text: DNMT3A: R882H

PubMed Link: 36859473

Variant Present in the following documents:

• molce-46-2-86.pdf

View BVdb publication page

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Development of a Next-generation Sequencing-based Gene Panel Test to Detect Measurable Residual Disease in Acute Myeloid Leukemia.

Annals Of Laboratory Medicine

Kim, Jin Ju JJ; Jang, Ji Eun JE; Lee, Hyeon Ah HA; Park, Mi Ri MR; Kook, Hye Won HW; Lee, Seung-Tae ST; Choi, Jong Rak JR; Min, Yoo Hong YH; Shin, Saeam S; Cheong, June-Won JW

Publication Date: 2023-07-01

Variant appearance in text: DNMT3A: 2645G>A

PubMed Link: 36843401

Variant Present in the following documents:

• Main text
• alm-43-4-328-supple6.pdf
• alm-43-4-328.pdf

View BVdb publication page

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Analysis of clinical and genomic profiles of therapy-related myeloid neoplasm in Korea.

Human Genomics

Yun, Jiwon J; Song, Hyojin H; Kim, Sung-Min SM; Kim, Soonok S; Kwon, Seok Ryun SR; Lee, Young Eun YE; Jeong, Dajeong D; Park, Jae Hyeon JH; Kwon, Sunghoon S; Yun, Hongseok H; Lee, Dong Soon DS

Publication Date: 2023-02-23

Variant appearance in text: DNMT3A: 2645G>A; Arg882His

PubMed Link: 36814285

Variant Present in the following documents:

• 40246_2023_458_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Impact of gene alterations on clinical outcome in young adults with myelodysplastic syndromes.

Scientific Reports

Konishi, Tatsuya T; Sadato, Daichi D; Toya, Takashi T; Hirama, Chizuko C; Kishida, Yuya Y; Nagata, Akihito A; Yamada, Yuta Y; Shingai, Naoki N; Shimizu, Hiroaki H; Najima, Yuho Y; Kobayashi, Takeshi T; Haraguchi, Kyoko K; Okuyama, Yoshiki Y; Harada, Hironori H; Ohashi, Kazuteru K; Harada, Yuka Y; Doki, Noriko N

Publication Date: 2023-02-14

Variant appearance in text: DNMT3A: 2645G>A; Arg882His

PubMed Link: 36788335

Variant Present in the following documents:

• 41598_2023_29794_MOESM2_ESM.xlsx, sheet 2

View BVdb publication page

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Dynamics of age- versus therapy-related clonal hematopoiesis in long-term survivors of pediatric cancer.

Cancer Discovery

Hagiwara, Kohei K; Natarajan, Sivaraman S; Wang, Zhaoming Z; Zubair, Haseeb H; Mulder, Heather L HL; Dong, Li L; Plyler, Emily M EM; Thimmaiah, Padma P; Ma, Xiaotu X; Ness, Kirsten K KK; Li, Zhenghong Z; Mulrooney, Daniel A DA; Wilson, Carmen L CL; Yasui, Yutaka Y; Hudson, Melissa M MM; Easton, John J; Robison, Leslie L LL; Zhang, Jinghui J

Publication Date: 2023-02-08

Variant appearance in text: DNMT3A: R882H

PubMed Link: 36751942

Variant Present in the following documents:

• cd-22-0956_tables_s2_s7_s8_s9_suppst1.xlsx, sheet 4
• cd-22-0956_tables_s2_s7_s8_s9_suppst1.xlsx, sheet 2
• cd-22-0956_tables_s2_s7_s8_s9_suppst1.xlsx, sheet 1

View BVdb publication page

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Resistance Mechanism of Acute Myeloid Leukemia Cells Against Daunorubicin and Cytarabine: A Literature Review.

Cureus

Arwanih, Elly Y EY; Louisa, Melva M; Rinaldi, Ikhwan I; Wanandi, Septelia I SI

Publication Date: 2022-12

Variant appearance in text: DNMT3A: R882H

PubMed Link: 36726936

Variant Present in the following documents:

• cureus-0014-00000033165.pdf

View BVdb publication page

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Genomic complexity predicts resistance to endocrine therapy and CDK4/6 inhibition in hormone receptor-positive (HR+)/HER2-negative metastatic breast cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Davis, Andrew A AA; Luo, Jingqin J; Zheng, Tiantian T; Dai, Chao C; Dong, Xiaoxi X; Tan, Lu L; Suresh, Rama R; Ademuyiwa, Foluso O FO; Rigden, Caron C; Rearden, Timothy P TP; Clifton, Katherine K; Weilbaecher, Katherine K; Frith, Ashley A; Tandra, Pavankumar K PK; Summa, Tracy T; Haas, Brittney B; Thomas, Shana S; Hernandez-Aya, Leonel F LF; Peterson, Lindsay L LL; Wang, Xiaohong X; Luo, Shujun J SJ; Zhou, Kemin K; Du, Pan P; Jia, Shidong S; King, Bonnie L BL; Krishnamurthy, Jairam J; Ma, Cynthia X CX

Publication Date: 2023-01-24

Variant appearance in text: DNMT3A: 2645G>A; Arg882His

PubMed Link: 36693175

Variant Present in the following documents:

• ccr-22-2177_supplementary_data_s1_suppds1.xlsx, sheet 3

View BVdb publication page

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Systemic structural analysis of alterations reveals a common structural basis of driver mutations in cancer.

Nar Cancer

Meirson, Tomer T; Bomze, David D; Schueler-Furman, Ora O; Stemmer, Salomon M SM; Markel, Gal G

Publication Date: 2023-03

Variant appearance in text: DNMT3A: R882H

PubMed Link: 36683915

Variant Present in the following documents:

• zcac040.pdf

View BVdb publication page

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Epigenetic Modification of Cytosines in Hematopoietic Differentiation and Malignant Transformation.

International Journal Of Molecular Sciences

An, Jungeun J; Ko, Myunggon M

Publication Date: 2023-01-15

Variant appearance in text: DNMT3A: R882H

PubMed Link: 36675240

Variant Present in the following documents:

• Main text
• ijms-24-01727.pdf

View BVdb publication page

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VEXAS syndrome: a new paradigm for adult-onset monogenic autoinflammatory diseases.

Internal And Emergency Medicine

Vitale, Antonio A; Caggiano, Valeria V; Bimonte, Antonio A; Caroni, Federico F; Tosi, Gian Marco GM; Fabbiani, Alessandra A; Renieri, Alessandra A; Bocchia, Monica M; Frediani, Bruno B; Fabiani, Claudia C; Cantarini, Luca L

Publication Date: 2023-01-20

Variant appearance in text: DNMT3A: Arg882His

PubMed Link: 36662445

Variant Present in the following documents:

• Main text
• 11739_2023_Article_3193.pdf

View BVdb publication page

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Differential expression of m5C RNA methyltransferase genes NSUN6 and NSUN7 in Alzheimer's disease and traumatic brain injury.

Molecular Neurobiology

PerezGrovas-Saltijeral, Adriana A; Rajkumar, Anto P AP; Knight, Helen Miranda HM

Publication Date: 2023-01-17

Variant appearance in text: DNMT3A: R882H

PubMed Link: 36646969

Variant Present in the following documents:

• 12035_2022_Article_3195.pdf

View BVdb publication page

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Targeting DNA Methylation in Leukemia, Myelodysplastic Syndrome, and Lymphoma: A Potential Diagnostic, Prognostic, and Therapeutic Tool.

International Journal Of Molecular Sciences

Kalinkova, Lenka L; Sevcikova, Aneta A; Stevurkova, Viola V; Fridrichova, Ivana I; Ciernikova, Sona S

Publication Date: 2022-12-30

Variant appearance in text: DNMT3A: R882H

PubMed Link: 36614080

Variant Present in the following documents:

• Main text
• ijms-24-00633.pdf

View BVdb publication page

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How I Manage Transplant Ineligible Patients with Myelodysplastic Neoplasms.

Clinical Hematology International

Gurnari, Carmelo C; Xie, Zhuoer Z; Zeidan, Amer M AM

Publication Date: 2022-12-27

Variant appearance in text: DNMT3A: R882H

PubMed Link: 36574201

Variant Present in the following documents:

• Main text
• 44228_2022_Article_24.pdf

View BVdb publication page

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c-Kit M541L variant is related to ineffective hemopoiesis predisposing to clonal evolution in 3D in vitro biomimetic co-culture model of bone marrow niche.

Heliyon

Manzo, Paola P; Scala, Pasqualina P; Giudice, Valentina V; Gorrese, Marisa M; Bertolini, Angela A; Morini, Denise D; D'Alto, Francesca F; Pepe, Rita R; Pedicini, Antonio A; Izzo, Barbara B; Verdesca, Francesco F; Langella, Maddalena M; Serio, Bianca B; Della Porta, Giovanna G; Selleri, Carmine C

Publication Date: 2022-12

Variant appearance in text: DNMT3A: Arg882His

PubMed Link: 36478848

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Electrostatic anti-CD33-antibody-protamine nanocarriers as platform for a targeted treatment of acute myeloid leukemia.

Journal Of Hematology & Oncology

Bäumer, Nicole N; Scheller, Annika A; Wittmann, Lisa L; Faust, Andreas A; Apel, Mara M; Nimmagadda, Subbaiah Chary SC; Geyer, Christiane C; Grunert, Katharina K; Kellmann, Neele N; Peipp, Matthias M; Kailayangiri, Sareetha S; Gutierrez Suburu, Matias Ezequiel ME; Strassert, Cristian A CA; Schenk, Mathias M; Greune, Lilo L; Rüter, Christian C; Dersch, Petra P; Hartmann, Wolfgang W; Rossig, Claudia C; Neri, Dario D; Müller-Tidow, Carsten C; Schwöppe, Christian C; Schliemann, Christoph C; Khandanpour, Cyrus C; Lenz, Georg G; Berdel, Wolfgang E WE; Bäumer, Sebastian S

Publication Date: 2022-12-01

Variant appearance in text: DNMT3A: R882H

PubMed Link: 36457063

Variant Present in the following documents:

• Main text
• 13045_2022_Article_1390.pdf

View BVdb publication page

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Retained functional normal and preleukemic HSCs at diagnosis are associated to good prognosis in DNMT3Amut NPM1mut AMLs.

Blood Advances

Donato, Elisa E; Correia, Nadia C NC; Andresen, Carolin C; Karpova, Darja D; Würth, Roberto R; Klein, Corinna C; Sohn, Markus M; Przybylla, Adriana A; Zeisberger, Petra P; Rothfelder, Kathrin K; Salih, Helmut R HR; Bonig, Halvard H; Stasik, Sebastian S; Röllig, Christoph C; Dolnik, Anna A; Bullinger, Lars L; Buchholz, Frank F; Thiede, Christian C; Hübschmann, Daniel D; Trumpp, Andreas A

Publication Date: 2022-12-01

Variant appearance in text: DNMT3A: R882H

PubMed Link: 36453648

Variant Present in the following documents:

• BLOODA_ADV-2022-008497-mmc1.pdf

View BVdb publication page

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Clinical and molecular features of FLT3 juxtamembrane domain missense mutations in acute myeloid leukaemia.

Journal Of Cellular And Molecular Medicine

Jensen, Christopher E CE; Montgomery, Nathan D ND; Galeotti, Jonathan J; Foster, Matthew C MC; Zeidner, Joshua F JF

Publication Date: 2022-11-28

Variant appearance in text: DNMT3A: 2645G>A; R882H

PubMed Link: 36444394

Variant Present in the following documents:

• Main text
• JCMM-26-6079.pdf

View BVdb publication page

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Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Cheng, Wen-Yan WY; Li, Jian-Feng JF; Zhu, Yong-Mei YM; Lin, Xiang-Jie XJ; Wen, Li-Jun LJ; Zhang, Fan F; Zhang, Yu-Liang YL; Zhao, Ming M; Fang, Hai H; Wang, Sheng-Yue SY; Lin, Xiao-Jing XJ; Qiao, Niu N; Yin, Wei W; Zhang, Jia-Nan JN; Dai, Yu-Ting YT; Jiang, Lu L; Sun, Xiao-Jian XJ; Xu, Yi Y; Zhang, Tong-Tong TT; Chen, Su-Ning SN; Zhu, Hong-Hu HH; Chen, Zhu Z; Jin, Jie J; Wu, De-Pei DP; Shen, Yang Y; Chen, Sai-Juan SJ

Publication Date: 2022-12-06

Variant appearance in text: DNMT3A: 2645G>A; Arg882His

PubMed Link: 36442087

Variant Present in the following documents:

• pnas.2211429119.sd02.xlsx, sheet 1

View BVdb publication page

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A sex-informed approach to improve the personalised decision making process in myelodysplastic syndromes: a multicentre, observational cohort study.

The Lancet. Haematology

,

Publication Date: 2022-11-24

Variant appearance in text: DNMT3A: 2645G>A; R882H

PubMed Link: 36436542

Variant Present in the following documents:

• mmc2.xlsx, sheet 1

View BVdb publication page

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Systematic assessment and optimizing algorithm of tumor mutational burden calculation and their implications in clinical decision-making.

Frontiers In Oncology

Sun, Daqiang D; Xu, Meilin M; Pan, Chaohu C; Tang, Hongzhen H; Wang, Peng P; Wu, Dongfang D; Luo, Haitao H

Publication Date: 2022

Variant appearance in text: DNMT3A: 2645G>A

PubMed Link: 36425562

Variant Present in the following documents:

• Table_3.xlsx, sheet 1

View BVdb publication page

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An Isolated Mesenteric Presentation of a Nodal Peripheral T Cell Lymphoma with T Follicular Helper Cell Phenotype.

Hematology Reports

Keogh, Anna A; Lynott, Fiona F; Papanicolau-Sengos, Antonios A; Mohammed Nur, Mutaz M; Spillane, Aisling A; Quinn, Fiona F; ElHassadi, Ezzat E; Jaffe, Elaine S ES; Flavin, Richard R

Publication Date: 2022-11-15

Variant appearance in text: DNMT3A: Arg882His

PubMed Link: 36412627

Variant Present in the following documents:

• hematolrep-14-00047.pdf

View BVdb publication page

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Integrated gene analyses of de novo variants from 46,612 trios with autism and developmental disorders.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Wang, Tianyun T; Kim, Chang N CN; Bakken, Trygve E TE; Gillentine, Madelyn A MA; Henning, Barbara B; Mao, Yafei Y; Gilissen, Christian C; , ; Nowakowski, Tomasz J TJ; Eichler, Evan E EE

Publication Date: 2022-11-15

Variant appearance in text: DNMT3A: 2645G>A; Arg882His

PubMed Link: 36350923

Variant Present in the following documents:

• pnas.2203491119.sd01.xlsx, sheet 1

View BVdb publication page

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Genomics improves risk stratification of adults with T-cell acute lymphoblastic leukemia patients enrolled in measurable residual disease-oriented trials.

Haematologica

González-Gil, Celia C; Morgades, Mireia M; Lopes, Thaysa T; Fuster-Tormo, Francisco F; García-Chica, Jesús J; Zhao, Ran R; Montesinos, Pau P; Torrent, Anna A; Diaz-Beya, Marina M; Coll, Rosa R; Hermosín, Lourdes L; Mercadal, Santiago S; González-Campos, José J; Zamora, Lurdes L; Artola, Teresa T; Vall-Llovera, Ferran F; Tormo, Mar M; Gil-Cortés, Cristina C; Barba, Pere P; Novo, Andrés A; Ribera, Jordi J; Bernal, Teresa T; De Ugarriza, Paula López PL; Queipo, María-Paz MP; Martínez-Sánchez, Pilar P; Giménez, Alicia A; González-Martínez, Teresa T; Cladera, Antonia A; Cervera, José J; Fernández-Martín, Rosa R; Ardaiz, María Ángeles MÁ; Vidal, María Jesús MJ; Baena, Ángela Á; López-Bigas, Nuria N; Bigas, Anna A; Maciejewski, Jaroslaw J; Orfao, Alberto A; Ribera, Josep Maria JM; Genescà, Eulalia E

Publication Date: 2022-11-03

Variant appearance in text: DNMT3A: R882H

PubMed Link: 36325893

Variant Present in the following documents:

• 108969.pdf

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Increased prevalence of clonal hematopoiesis of indeterminate potential in hospitalized patients with COVID-19.

Frontiers In Immunology

Schenz, Judith J; Rump, Katharina K; Siegler, Benedikt Hermann BH; Hemmerling, Inga I; Rahmel, Tim T; Thon, Jan N JN; Nowak, Hartmuth H; Fischer, Dania D; Hafner, Anna A; Tichy, Lucas L; Bomans, Katharina K; Meggendorfer, Manja M; Koos, Björn B; von Groote, Thilo T; Zarbock, Alexander A; Fiedler, Mascha O MO; Zemva, Johanna J; Larmann, Jan J; Merle, Uta U; Adamzik, Michael M; Müller-Tidow, Carsten C; Haferlach, Torsten T; Leuschner, Florian F; Weigand, Markus A MA

Publication Date: 2022

Variant appearance in text: DNMT3A: 2645G>A; Arg882His

PubMed Link: 36311800

Variant Present in the following documents:

• DataSheet_1.pdf

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DNMT3A R882H mutation drives daunorubicin resistance in acute myeloid leukemia via regulating NRF2/NQO1 pathway.

Cell Communication And Signaling : Ccs

Chu, Xuan X; Zhong, Liang L; Dan, Wenran W; Wang, Xiao X; Zhang, Zhonghui Z; Liu, Zhenyan Z; Lu, Yang Y; Shao, Xin X; Zhou, Ziwei Z; Chen, Shuyu S; Liu, Beizhong B

Publication Date: 2022-10-27

Variant appearance in text: DNMT3A: R882H

PubMed Link: 36303144

Variant Present in the following documents:

• 12964_2022_Article_978.pdf

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