Variant ID: 2-27741237-T-C

NM_001486.3(GCKR):c.1423-418T>C

This variant was identified in 600 publications




Publications:


Glucose metabolism-related gene polymorphisms as the risk predictors of type 2 diabetes.

Diabetology & Metabolic Syndrome
C Li, Y Yang, X Liu, Z Li, H Liu, Q Tan
Publication Date: 2020-11-04

Variant appearance in text: rs780094
PubMed Link: 33292424
Variant Present in the following documents:
  • Main text
View BVdb publication page



Modeling Non-Alcoholic Fatty Liver Disease (NAFLD) Using "Good-Fit" Genome-Editing Tools.

Cells
U Kim, N Kim, HY Shin
Publication Date: 2020-12-01

Variant appearance in text: rs780094
PubMed Link: 33271878
Variant Present in the following documents:
  • Main text
View BVdb publication page



Noncoding RNAs in Nonalcoholic Fatty Liver Disease: Potential Diagnosis and Prognosis Biomarkers.

Disease Markers
O Khalifa, K Errafii, NS Al-Akl, A Arredouani
Publication Date: 2020

Variant appearance in text: rs780094
PubMed Link: 33133304
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic Variants Associated with Non-Alcoholic Fatty Liver Disease Do Not Associate with Measures of Sub-Clinical Atherosclerosis: Results from the IMPROVE Study.

Genes
L Castaldo, F Laguzzi, RJ Strawbridge, D Baldassarre, F Veglia, L Vigo, E Tremoli, U de Faire, P Eriksson, AJ Smit, J Aubrecht, K Leander, M Pirro, P Giral, A Ritieni, G Di Minno, A Mälarstig, B Gigante
Publication Date: 2020-10-22

Variant appearance in text: rs780094
PubMed Link: 33105679
Variant Present in the following documents:
  • Main text
View BVdb publication page



Human and molecular genetics shed lights on fatty liver disease and diabetes conundrum.

Endocrinology, Diabetes & Metabolism
F Tavaglione, G Targher, L Valenti, S Romeo
Publication Date: 2020-10

Variant appearance in text: rs780094
PubMed Link: 33102799
Variant Present in the following documents:
  • Main text
View BVdb publication page



Diagnostic and interventional circulating biomarkers in nonalcoholic steatohepatitis.

Endocrinology, Diabetes & Metabolism
MA Tincopa
Publication Date: 2020-10

Variant appearance in text: rs780094
PubMed Link: 33102798
Variant Present in the following documents:
  • Main text
View BVdb publication page



Effects of a Lifestyle-Modification Program on Blood-Glucose Regulation and Health Promotion in Diabetic Patients: A Randomized Controlled Trial.

Journal Of Lifestyle Medicine
SW Shin, SJ Jung, ES Jung, JH Hwang, WR Kim, BO So, BH Park, SO Lee, BH Cho, TS Park, YG Kim, SW Chae
Publication Date: 2020-07-31

Variant appearance in text: rs780094
PubMed Link: 32995335
Variant Present in the following documents:
  • Main text
View BVdb publication page



Precision medicine in nonalcoholic fatty liver disease: New therapeutic insights from genetics and systems biology.

Clinical And Molecular Hepatology
S Sookoian, CJ Pirola
Publication Date: 2020-10

Variant appearance in text: rs780094
PubMed Link: 32906228
Variant Present in the following documents:
  • Main text
View BVdb publication page



Nonalcoholic Fatty Liver Disease (NAFLD) and Hepatic Cytochrome P450 (CYP) Enzymes.

Pharmaceuticals (Basel, Switzerland)
R Jamwal, BJ Barlock
Publication Date: 2020-08-29

Variant appearance in text: rs780094
PubMed Link: 32872474
Variant Present in the following documents:
  • Main text
View BVdb publication page



Serum Calcium Levels and Parkinson's Disease: A Mendelian Randomization Study.

Frontiers In Genetics
Y Wang, L Gao, W Lang, H Li, P Cui, N Zhang, W Jiang
Publication Date: 2020

Variant appearance in text: rs780094
PubMed Link: 32849817
Variant Present in the following documents:
  • Main text
View BVdb publication page



Validating a non-invasive, ALT-based non-alcoholic fatty liver phenotype in the million veteran program.

Plos One
M Serper, M Vujkovic, DE Kaplan, RM Carr, KM Lee, Q Shao, DR Miller, PD Reaven, LS Phillips, CJ O'Donnell, JB Meigs, PWF Wilson, R Vickers-Smith, HR Kranzler, AC Justice, JM Gaziano, S Muralidhar, S Pyarajan, SL DuVall, TL Assimes, JS Lee, PS Tsao, DJ Rader, SM Damrauer, JA Lynch, D Saleheen, BF Voight, KM Chang,
Publication Date: 2020

Variant appearance in text: rs780094
PubMed Link: 32841307
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetically Mediated Lipid Metabolism and Risk of Insulin Resistance: Insights from Mendelian Randomization Studies.

Journal Of Lipid And Atherosclerosis
SY Bu
Publication Date: 2019-09

Variant appearance in text: rs780094
PubMed Link: 32821703
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-Wide Association Study of Liver Fat: The Multiethnic Cohort Adiposity Phenotype Study.

Hepatology Communications
SL Park, Y Li, X Sheng, V Hom, L Xia, K Zhao, L Pooler, VW Setiawan, U Lim, KR Monroe, LR Wilkens, BS Kristal, JW Lampe, M Hullar, J Shepherd, LLM Loo, T Ernst, AA Franke, M Tiirikainen, CA Haiman, DO Stram, L Le Marchand, I Cheng
Publication Date: 2020-08

Variant appearance in text: rs780094
PubMed Link: 32766472
Variant Present in the following documents:
  • Main text
View BVdb publication page



Obesity, clinical, and genetic predictors for glycemic progression in Chinese patients with type 2 diabetes: A cohort study using the Hong Kong Diabetes Register and Hong Kong Diabetes Biobank.

Plos Medicine
G Jiang, AO Luk, CHT Tam, ES Lau, R Ozaki, EYK Chow, APS Kong, CKP Lim, KF Lee, SC Siu, G Hui, CC Tsang, KP Lau, JYY Leung, MW Tsang, G Kam, IT Lau, JK Li, VT Yeung, E Lau, S Lo, SKS Fung, YL Cheng, CC Chow, ER Pearson, WY So, JCN Chan, RCW Ma, ,
Publication Date: 2020-07

Variant appearance in text: rs780094
PubMed Link: 32722720
Variant Present in the following documents:
  • Main text
View BVdb publication page



The role of omics in the pathophysiology, diagnosis and treatment of non-alcoholic fatty liver disease.

Metabolism: Clinical And Experimental
N Perakakis, K Stefanakis, CS Mantzoros
Publication Date: 2020-10

Variant appearance in text: rs780094
PubMed Link: 32712221
Variant Present in the following documents:
  • Main text
View BVdb publication page



A Scoping Review of Interactions between Omega-3 Long-Chain Polyunsaturated Fatty Acids and Genetic Variation in Relation to Cancer Risk.

Nutrients
K Yurko-Mauro, M Van Elswyk, L Teo
Publication Date: 2020-06-02

Variant appearance in text: rs780094
PubMed Link: 32498320
Variant Present in the following documents:
  • Main text
View BVdb publication page



Hepatic NADH reductive stress underlies common variation in metabolic traits.

Nature
RP Goodman, AL Markhard, H Shah, R Sharma, OS Skinner, CB Clish, A Deik, A Patgiri, YH Hsu, R Masia, HL Noh, S Suk, O Goldberger, JN Hirschhorn, G Yellen, JK Kim, VK Mootha
Publication Date: 2020-07

Variant appearance in text: rs780094
PubMed Link: 32461692
Variant Present in the following documents:
  • Main text
View BVdb publication page



Unique insights from ClinicalTrials.gov by mining protein mutations and RSids in addition to applying the Human Phenotype Ontology.

Plos One
S Alag
Publication Date: 2020

Variant appearance in text: rs780094
PubMed Link: 32459809
Variant Present in the following documents:
  • Main text
View BVdb publication page



The Impact of obesity and diabetes mellitus on pancreatic cancer: Molecular mechanisms and clinical perspectives.

Journal Of Cellular And Molecular Medicine
B Quoc Lam, SK Shrivastava, A Shrivastava, S Shankar, RK Srivastava
Publication Date: 2020-07

Variant appearance in text: rs780094
PubMed Link: 32458441
Variant Present in the following documents:
  • Main text
View BVdb publication page



Shared genetic architecture and casual relationship between leptin levels and type 2 diabetes: large-scale cross-trait meta-analysis and Mendelian randomization analysis.

Bmj Open Diabetes Research & Care
X Wang, J Jia, T Huang
Publication Date: 2020-04

Variant appearance in text: rs780094
PubMed Link: 32341051
Variant Present in the following documents:
  • Main text
View BVdb publication page



The impact of phenotype, ethnicity and genotype on progression of type 2 diabetes mellitus.

Endocrinology, Diabetes & Metabolism
A Thakarakkattil Narayanan Nair, LA Donnelly, AY Dawed, S Gan, RM Anjana, M Viswanathan, CNA Palmer, ER Pearson
Publication Date: 2020-04

Variant appearance in text: rs780094
PubMed Link: 32318630
Variant Present in the following documents:
  • Main text
View BVdb publication page



A Replication Study Identified Seven SNPs Associated with Quantitative Traits of Type 2 Diabetes among Chinese Population in A Cross-Sectional Study.

International Journal Of Environmental Research And Public Health
F Yuan, H Li, C Song, H Fang, R Wang, Y Zhang, W Gong, A Liu
Publication Date: 2020-04-03

Variant appearance in text: rs780094
PubMed Link: 32260174
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan.

Nature Communications
B Hollis, FR Day, AS Busch, DJ Thompson, ALG Soares, PRHJ Timmers, A Kwong, DF Easton, PK Joshi, NJ Timpson, , , KK Ong, JRB Perry
Publication Date: 2020-03-24

Variant appearance in text: rs780094
PubMed Link: 32210231
Variant Present in the following documents:
  • Main text
View BVdb publication page



Gene-environment interactions due to quantile-specific heritability of triglyceride and VLDL concentrations.

Scientific Reports
PT Williams
Publication Date: 2020-03-11

Variant appearance in text: rs780094
PubMed Link: 32161301
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mendelian Randomization of Circulating Polyunsaturated Fatty Acids and Colorectal Cancer Risk.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
NK Khankari, BL Banbury, MC Borges, P Haycock, D Albanes, V Arndt, SI Berndt, S Bézieau, H Brenner, PT Campbell, G Casey, AT Chan, J Chang-Claude, DV Conti, M Cotterchio, DR English, JC Figueiredo, GG Giles, EL Giovannucci, MJ Gunter, J Hampe, M Hoffmeister, JL Hopper, MA Jenkins, AD Joshi, LL Marchand, M Lemire, CI Li, L Li, A Lindblom, V Martín, V Moreno, PA Newcomb, K Offit, PDP Pharoah, G Rennert, LC Sakoda, C Schafmayer, SL Schmit, ML Slattery, M Song, SN Thibodeau, CM Ulrich, SJ Weinstein, E White, AK Win, A Wolk, MO Woods, AH Wu, Q Cai, JC Denny, TL Edwards, HJ Murff, SB Gruber, U Peters, W Zheng
Publication Date: 2020-04

Variant appearance in text: rs780094
PubMed Link: 32051193
Variant Present in the following documents:
  • Main text
View BVdb publication page



From NASH to diabetes and from diabetes to NASH: Mechanisms and treatment options.

Jhep Reports : Innovation In Hepatology
A Gastaldelli, K Cusi
Publication Date: 2019-10

Variant appearance in text: rs780094
PubMed Link: 32039382
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pleiotropic Effects of a KCNQ1 Variant on Lipid Profiles and Type 2 Diabetes: A Family-Based Study in China.

Journal Of Diabetes Research
X Wang, J Wu, Y Wu, M Wang, Z Wang, T Wu, D Chen, X Tang, X Qin, Y Wu, Y Hu
Publication Date: 2020

Variant appearance in text: rs780094
PubMed Link: 32016123
Variant Present in the following documents:
  • Main text
View BVdb publication page



Causal relationships between lipid and glycemic levels in an Indian population: A bidirectional Mendelian randomization approach.

Plos One
T Agarwal, T Lyngdoh, F Dudbridge, GR Chandak, S Kinra, D Prabhakaran, KS Reddy, CL Relton, G Davey Smith, S Ebrahim, V Gupta, GK Walia
Publication Date: 2020

Variant appearance in text: rs780094
PubMed Link: 31995593
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetics of Non-Alcoholic Fatty Liver and Cardiovascular Disease: Implications for Therapy?

Frontiers In Pharmacology
K Chandrasekharan, W Alazawi
Publication Date: 2019

Variant appearance in text: rs780094
PubMed Link: 31969816
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic effects on hypertriglyceridemic waist phenotype: rs780094, rs10830963, rs151290, and rs972283 polymorphisms and the interactions between them and behavior risk factors.

International Journal Of Clinical And Experimental Pathology
J Wang, J Zhang, J Li, Z Liu, K Gao
Publication Date: 2017

Variant appearance in text: rs780094
PubMed Link: 31966885
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of GCKR rs780094 polymorphism with circulating lipid levels in type 2 diabetes and hyperuricemia in Uygur Chinese.

International Journal Of Clinical And Experimental Pathology
L Wang, Q Ma, H Yao, LJ He, BB Fang, W Cai, B Zhang, ZQ Wang, YX Su, GL Du, SX Wang, ZX Zhang, QQ Hou, R Cai, FP He
Publication Date: 2018

Variant appearance in text: rs780094
PubMed Link: 31949869
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of rs780094 polymorphism of glucokinase regulatory protein with non-alcoholic fatty liver disease.

Bmc Research Notes
S Mohammadi, S Farajnia, M Shadmand, F Mohseni, R Baghban
Publication Date: 2020-01-10

Variant appearance in text: rs780094
PubMed Link: 31924263
Variant Present in the following documents:
  • Main text
View BVdb publication page



PNPLA3-A Potential Therapeutic Target for Personalized Treatment of Chronic Liver Disease.

Frontiers In Medicine
XC Dong
Publication Date: 2019

Variant appearance in text: rs780094
PubMed Link: 31921875
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of GCKR Gene Polymorphisms with the Risk of Nonalcoholic Fatty Liver Disease and Coronary Artery Disease in a Chinese Northern Han Population.

Journal Of Clinical And Translational Hepatology
H Gao, S Liu, Z Zhao, X Yu, Q Liu, Y Xin, S Xuan
Publication Date: 2019-12-28

Variant appearance in text: rs780094
PubMed Link: 31915598
Variant Present in the following documents:
  • Main text
  • JCTH-7-297.pdf
View BVdb publication page



Genome-wide association study of metabolic syndrome in Korean populations.

Plos One
SW Oh, JE Lee, E Shin, H Kwon, EK Choe, SY Choi, H Rhee, SH Choi
Publication Date: 2020

Variant appearance in text: rs780094
PubMed Link: 31910446
Variant Present in the following documents:
  • Main text
View BVdb publication page



Impact of glycemic traits, type 2 diabetes and metformin use on breast and prostate cancer risk: a Mendelian randomization study.

Bmj Open Diabetes Research & Care
SL Au Yeung, CM Schooling
Publication Date: 2019

Variant appearance in text: rs780094
PubMed Link: 31908803
Variant Present in the following documents:
  • bmjdrc-2019-000872supp001.pdf
View BVdb publication page



Progressive effects of single-nucleotide polymorphisms on 16 phenotypic traits based on longitudinal data.

Genes & Genomics
D Li, H Kang, S Lee, S Won
Publication Date: 2020-04

Variant appearance in text: rs780094
PubMed Link: 31902109
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pure additive contribution of genetic variants to a risk prediction model using propensity score matching: application to type 2 diabetes.

Genomics & Informatics
C Park, N Jiang, T Park
Publication Date: 2019-12

Variant appearance in text: rs780094
PubMed Link: 31896247
Variant Present in the following documents:
  • Main text
View BVdb publication page



Data on a genome-wide association study of type 2 diabetes in a Maya population.

Data In Brief
A Totomoch-Serra, MG Domínguez-Cruz, ML Muñoz, MG García-Escalante, J Burgueño, Á Díaz-Badillo, N Valadez-González, DP Escalante
Publication Date: 2020-02

Variant appearance in text: rs780094
PubMed Link: 31872004
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Plasma Phospholipid Fatty Acids, FADS1 and Risk of 15 Cardiovascular Diseases: A Mendelian Randomisation Study.

Nutrients
S Yuan, M Bäck, M Bruzelius, AM Mason, S Burgess, S Larsson
Publication Date: 2019-12-07

Variant appearance in text: rs780094
PubMed Link: 31817859
Variant Present in the following documents:
  • Main text
View BVdb publication page



New Perspectives in Pediatric Nonalcoholic Fatty Liver Disease: Epidemiology, Genetics, Diagnosis, and Natural History.

Pediatric Gastroenterology, Hepatology & Nutrition
JS Ko
Publication Date: 2019-11

Variant appearance in text: rs780094
PubMed Link: 31777715
Variant Present in the following documents:
  • Main text
  • pghn-22-501.pdf
View BVdb publication page



Candidate Gene and Genome-Wide Association Studies for Circulating Leptin Levels Reveal Population and Sex-Specific Associations in High Cardiovascular Risk Mediterranean Subjects.

Nutrients
C Ortega-Azorín, O Coltell, EM Asensio, JV Sorlí, JI González, O Portolés, C Saiz, R Estruch, JB Ramírez-Sabio, A Pérez-Fidalgo, JM Ordovas, D Corella
Publication Date: 2019-11-13

Variant appearance in text: rs780094
PubMed Link: 31766143
Variant Present in the following documents:
  • Main text
  • nutrients-11-02751.pdf
View BVdb publication page



SNP-Based Genetic Risk Score Modeling Suggests No Increased Genetic Susceptibility of the Roma Population to Type 2 Diabetes Mellitus.

Genes
NA Werissa, P Piko, S Fiatal, Z Kosa, J Sandor, R Adany
Publication Date: 2019-11-19

Variant appearance in text: rs780094
PubMed Link: 31752367
Variant Present in the following documents:
  • Main text
  • genes-10-00942.pdf
View BVdb publication page



Metabolic Signature of Hepatic Fibrosis: From Individual Pathways to Systems Biology.

Cells
ML Chang, SS Yang
Publication Date: 2019-11-12

Variant appearance in text: rs780094
PubMed Link: 31726658
Variant Present in the following documents:
  • Main text
  • cells-08-01423.pdf
View BVdb publication page



Non-alcoholic fatty liver disease and cardiovascular disease: assessing the evidence for causality.

Diabetologia
MCGJ Brouwers, N Simons, CDA Stehouwer, A Isaacs
Publication Date: 2020-02

Variant appearance in text: rs780094
PubMed Link: 31713012
Variant Present in the following documents:
  • Main text
View BVdb publication page



Assessing Causality in Associations of Serum Calcium and Magnesium Levels With Heart Failure: A Two-Sample Mendelian Randomization Study.

Frontiers In Genetics
E Helte, A Åkesson, SC Larsson
Publication Date: 2019

Variant appearance in text: rs780094
PubMed Link: 31708976
Variant Present in the following documents:
  • Main text
View BVdb publication page



A Novel Phosphoinositide-3-kinase Adapter Protein 1 Gene Missense Mutation in Familial Cirrhosis.

Journal Of Clinical And Experimental Hepatology
C Abby Philips, M Agarwal, N Phadke, S Rajesh, G Padsalgi, R Ahamed, P Augustine
Publication Date: 2019

Variant appearance in text: rs780094
PubMed Link: 31695254
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of genetic variants related to plasma fatty acids with type 2 diabetes mellitus and glycaemic traits: a Mendelian randomisation study.

Diabetologia
S Yuan, SC Larsson
Publication Date: 2020-01

Variant appearance in text: rs780094
PubMed Link: 31690987
Variant Present in the following documents:
  • 125_2019_5019_MOESM1_ESM.xlsx
  • 125_2019_Article_5019.pdf
  • aaaaaMain text
View BVdb publication page



Lack of association between modifiable exposures and glioma risk: a Mendelian randomization analysis.

Neuro-Oncology
CN Saunders, AJ Cornish, B Kinnersley, PJ Law, EB Claus, D Il'yasova, J Schildkraut, JS Barnholtz-Sloan, SH Olson, JL Bernstein, RK Lai, S Chanock, P Rajaraman, C Johansen, RB Jenkins, BS Melin, MR Wrensch, M Sanson, ML Bondy, RS Houlston
Publication Date: 2020-02-20

Variant appearance in text: rs780094
PubMed Link: 31665421
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of Genetic Variants Related to Serum Calcium Levels with Reduced Bone Mineral Density.

The Journal Of Clinical Endocrinology And Metabolism
GH Li, C Robinson-Cohen, S Sahni, PC Au, KC Tan, AW Kung, CL Cheung
Publication Date: 2020-03-01

Variant appearance in text: rs780094
PubMed Link: 31650181
Variant Present in the following documents:
  • Main text
View BVdb publication page



A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context.

Nature Communications
A Gallois, J Mefford, A Ko, A Vaysse, H Julienne, M Ala-Korpela, M Laakso, N Zaitlen, P Pajukanta, H Aschard
Publication Date: 2019-10-21

Variant appearance in text: rs780094
PubMed Link: 31636271
Variant Present in the following documents:
  • 41467_2019_12703_MOESM11_ESM.xlsx
  • 41467_2019_12703_MOESM3_ESM.xlsx
  • 41467_2019_12703_MOESM4_ESM.xlsx
  • 41467_2019_12703_MOESM6_ESM.xlsx
  • 41467_2019_12703_MOESM8_ESM.xlsx
View BVdb publication page



Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study.

Plos Medicine
X Li, X Meng, Y He, A Spiliopoulou, M Timofeeva, WQ Wei, A Gifford, T Yang, T Varley, I Tzoulaki, P Joshi, JC Denny, P Mckeigue, H Campbell, E Theodoratou
Publication Date: 2019-10

Variant appearance in text: rs780094
PubMed Link: 31626644
Variant Present in the following documents:
  • pmed.1002937.pdf
View BVdb publication page



Genetic analysis of hsCRP in American Indians: The Strong Heart Family Study.

Plos One
LG Best, P Balakrishnan, SA Cole, K Haack, JM Kocarnik, N Pankratz, MZ Anderson, N Franceschini, BV Howard, ET Lee, KE North, JG Umans, JM Yracheta, A Navas-Acien, VS Voruganti
Publication Date: 2019

Variant appearance in text: rs780094
PubMed Link: 31622379
Variant Present in the following documents:
  • Main text
View BVdb publication page



Bayesian multivariate reanalysis of large genetic studies identifies many new associations.

Plos Genetics
MC Turchin, M Stephens
Publication Date: 2019-10

Variant appearance in text: rs780094
PubMed Link: 31596850
Variant Present in the following documents:
  • pgen.1008431.s006.xls
  • pgen.1008431.s007.xls
View BVdb publication page



Genetic predisposition to type 2 diabetes is associated with severity of coronary artery disease in patients with acute coronary syndromes.

Cardiovascular Diabetology
Q Zheng, J Jiang, Y Huo, D Chen
Publication Date: 2019-10-08

Variant appearance in text: rs780094
PubMed Link: 31594547
Variant Present in the following documents:
  • 12933_2019_930_MOESM1_ESM.docx
  • 12933_2019_Article_930.pdf
  • aaaaaMain text
View BVdb publication page



Quantitative and Qualitative Role of Antagonistic Heterogeneity in Genetics of Blood Lipids.

The Journals Of Gerontology. Series A, Biological Sciences And Medical Sciences
AM Kulminski, Y Loika, A Nazarian, I Culminskaya
Publication Date: 2020-09-25

Variant appearance in text: rs780094
PubMed Link: 31566214
Variant Present in the following documents:
  • Main text
View BVdb publication page



Overview of the Pathogenesis, Genetic, and Non-Invasive Clinical, Biochemical, and Scoring Methods in the Assessment of NAFLD.

International Journal Of Environmental Research And Public Health
V Kupčová, M Fedelešová, J Bulas, P Kozmonová, L Turecký
Publication Date: 2019-09-24

Variant appearance in text: rs780094
PubMed Link: 31554274
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.

Nature Communications
A Teumer, Y Li, S Ghasemi, BP Prins, M Wuttke, T Hermle, A Giri, KB Sieber, C Qiu, H Kirsten, A Tin, AY Chu, N Bansal, MF Feitosa, L Wang, JF Chai, M Cocca, C Fuchsberger, M Gorski, A Hoppmann, K Horn, M Li, J Marten, D Noce, T Nutile, S Sedaghat, G Sveinbjornsson, BO Tayo, PJ van der Most, Y Xu, Z Yu, L Gerstner, J Ärnlöv, SJL Bakker, D Baptista, ML Biggs, E Boerwinkle, H Brenner, R Burkhardt, RJ Carroll, ML Chee, ML Chee, M Chen, CY Cheng, JP Cook, J Coresh, T Corre, J Danesh, MH de Borst, A De Grandi, R de Mutsert, APJ de Vries, F Degenhardt, K Dittrich, J Divers, KU Eckardt, G Ehret, K Endlich, JF Felix, OH Franco, A Franke, BI Freedman, S Freitag-Wolf, RT Gansevoort, V Giedraitis, M Gögele, F Grundner-Culemann, DF Gudbjartsson, V Gudnason, P Hamet, TB Harris, AA Hicks, H Holm, VHX Foo, SJ Hwang, MA Ikram, E Ingelsson, VWV Jaddoe, J Jakobsdottir, NS Josyula, B Jung, M Kähönen, CC Khor, W Kiess, W Koenig, A Körner, P Kovacs, H Kramer, BK Krämer, F Kronenberg, LA Lange, CD Langefeld, JJ Lee, T Lehtimäki, W Lieb, SC Lim, L Lind, CM Lindgren, J Liu, M Loeffler, LP Lyytikäinen, A Mahajan, JC Maranville, D Mascalzoni, B McMullen, C Meisinger, T Meitinger, K Miliku, DO Mook-Kanamori, M Müller-Nurasyid, JC Mychaleckyj, M Nauck, K Nikus, B Ning, R Noordam, JO Connell, I Olafsson, ND Palmer, A Peters, AI Podgornaia, B Ponte, T Poulain, PP Pramstaller, TJ Rabelink, LM Raffield, DF Reilly, R Rettig, M Rheinberger, KM Rice, F Rivadeneira, H Runz, KA Ryan, C Sabanayagam, KU Saum, B Schöttker, CM Shaffer, Y Shi, AV Smith, K Strauch, M Stumvoll, BB Sun, S Szymczak, ES Tai, NYQ Tan, KD Taylor, A Teren, YC Tham, J Thiery, CHL Thio, H Thomsen, U Thorsteinsdottir, A Tönjes, J Tremblay, AG Uitterlinden, P van der Harst, N Verweij, S Vogelezang, U Völker, M Waldenberger, C Wang, OD Wilson, C Wong, TY Wong, Q Yang, M Yasuda, S Akilesh, M Bochud, CA Böger, O Devuyst, TL Edwards, K Ho, AP Morris, A Parsa, SA Pendergrass, BM Psaty, JI Rotter, K Stefansson, JG Wilson, K Susztak, H Snieder, IM Heid, M Scholz, AS Butterworth, AM Hung, C Pattaro, A Köttgen
Publication Date: 2019-09-11

Variant appearance in text: rs780094
PubMed Link: 31511532
Variant Present in the following documents:
  • 41467_2019_11576_MOESM14_ESM.xlsx
View BVdb publication page



Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology.

Nature Communications
Y Tanigawa, J Li, JM Justesen, H Horn, M Aguirre, C DeBoever, C Chang, B Narasimhan, K Lage, T Hastie, CY Park, G Bejerano, E Ingelsson, MA Rivas
Publication Date: 2019-09-06

Variant appearance in text: rs780094
PubMed Link: 31492854
Variant Present in the following documents:
  • 41467_2019_11953_MOESM6_ESM.xlsx
View BVdb publication page



Vitamin D-Related Genes, Blood Vitamin D Levels and Colorectal Cancer Risk in Western European Populations.

Nutrients
V Fedirko, HB Mandle, W Zhu, DJ Hughes, A Siddiq, P Ferrari, I Romieu, E Riboli, B Bueno-de-Mesquita, FJB van Duijnhoven, PD Siersema, A Tjønneland, A Olsen, V Perduca, F Carbonnel, MC Boutron-Ruault, T Kühn, T Johnson, A Krasimira, A Trichopoulou, P Makrythanasis, D Thanos, S Panico, V Krogh, C Sacerdote, G Skeie, E Weiderpass, S Colorado-Yohar, N Sala, A Barricarte, MJ Sanchez, R Quirós, P Amiano, B Gylling, S Harlid, A Perez-Cornago, AK Heath, KK Tsilidis, D Aune, H Freisling, N Murphy, MJ Gunter, M Jenab
Publication Date: 2019-08-20

Variant appearance in text: rs780094
PubMed Link: 31434255
Variant Present in the following documents:
  • Main text
View BVdb publication page



The Liver in Children With Metabolic Syndrome.

Frontiers In Endocrinology
E D'Adamo, V Castorani, V Nobili
Publication Date: 2019

Variant appearance in text: rs780094
PubMed Link: 31428049
Variant Present in the following documents:
  • Main text
  • fendo-10-00514.pdf
View BVdb publication page



GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits.

Nature Communications
R Pazoki, E Evangelou, D Mosen-Ansorena, RC Pinto, I Karaman, P Blakeley, D Gill, V Zuber, P Elliott, I Tzoulaki, A Dehghan
Publication Date: 2019-08-13

Variant appearance in text: rs780094
PubMed Link: 31409800
Variant Present in the following documents:
  • 41467_2019_11451_MOESM17_ESM.xlsx
  • 41467_2019_11451_MOESM3_ESM.xlsx
  • 41467_2019_11451_MOESM5_ESM.xlsx
  • 41467_2019_11451_MOESM9_ESM.xlsx
View BVdb publication page



Is Hyperuricemia, an Early-Onset Metabolic Disorder, Causally Associated with Cardiovascular Disease Events in Han Chinese?

Journal Of Clinical Medicine
KM Chiang, YC Tsay, TC Vincent Ng, HC Yang, YT Huang, CH Chen, WH Pan
Publication Date: 2019-08-12

Variant appearance in text: rs780094
PubMed Link: 31408958
Variant Present in the following documents:
  • Main text
  • jcm-08-01202-s001.pdf
View BVdb publication page



Genetic predisposition to increased serum calcium, bone mineral density, and fracture risk in individuals with normal calcium levels: mendelian randomisation study.

Bmj (Clinical Research Ed.)
A Cerani, S Zhou, V Forgetta, JA Morris, K Trajanoska, F Rivadeneira, SC Larsson, K Michaëlsson, JB Richards
Publication Date: 2019-08-01

Variant appearance in text: rs780094
PubMed Link: 31371314
Variant Present in the following documents:
  • Main text
View BVdb publication page



Insulin Resistance Exacerbates Genetic Predisposition to Nonalcoholic Fatty Liver Disease in Individuals Without Diabetes.

Hepatology Communications
L Barata, MF Feitosa, LF Bielak, B Halligan, AS Baldridge, X Guo, LM Yerges-Armstrong, AV Smith, J Yao, ND Palmer, LB VanWagner, JJ Carr, YI Chen, M Allison, MJ Budoff, SK Handelman, SLR Kardia, TH Mosley, K Ryan, TB Harris, LJ Launer, V Gudnason, JI Rotter, M Fornage, LJ Rasmussen-Torvik, IB Borecki, JR O'Connell, PA Peyser, EK Speliotes, MA Province
Publication Date: 2019-07

Variant appearance in text: rs780094
PubMed Link: 31334442
Variant Present in the following documents:
  • Main text
  • HEP4-3-894-s001.docx
  • HEP4-3-894.pdf
View BVdb publication page



Plasma Phospholipid Fatty Acids and Risk of Atrial Fibrillation: A Mendelian Randomization Study.

Nutrients
S Yuan, SC Larsson
Publication Date: 2019-07-19

Variant appearance in text: rs780094
PubMed Link: 31331006
Variant Present in the following documents:
  • Main text
  • nutrients-11-01651-s001.xlsx
View BVdb publication page



GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network.

Bmc Medicine
B Namjou, T Lingren, Y Huang, S Parameswaran, BL Cobb, IB Stanaway, JJ Connolly, FD Mentch, B Benoit, X Niu, WQ Wei, RJ Carroll, JA Pacheco, ITW Harley, S Divanovic, DS Carrell, EB Larson, DJ Carey, S Verma, MD Ritchie, AG Gharavi, S Murphy, MS Williams, DR Crosslin, GP Jarvik, IJ Kullo, H Hakonarson, R Li, , SA Xanthakos, JB Harley
Publication Date: 2019-07-17

Variant appearance in text: rs780094
PubMed Link: 31311600
Variant Present in the following documents:
  • 12916_2019_1364_MOESM1_ESM.xlsx
  • 12916_2019_Article_1364.pdf
  • aaaaaMain text
View BVdb publication page



An intronic variant in the GCKR gene is associated with multiple lipids.

Scientific Reports
L Fernandes Silva, J Vangipurapu, T Kuulasmaa, M Laakso
Publication Date: 2019-07-15

Variant appearance in text: rs780094
PubMed Link: 31308433
Variant Present in the following documents:
  • Main text
View BVdb publication page



The relationship among GNB3 rs5443, PNPLA3 rs738409, GCKR rs780094 gene polymorphisms, type of maternal gestational weight gain and neonatal outcomes (STROBE-compliant article).

Medicine
C Mărginean, CO Mărginean, C Bănescu, LE Meliţ, F Tripon, M Iancu
Publication Date: 2019-07

Variant appearance in text: rs780094
PubMed Link: 31305457
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-wide Association Study of Change in Fasting Glucose over time in 13,807 non-diabetic European Ancestry Individuals.

Scientific Reports
CT Liu, J Merino, D Rybin, D DiCorpo, KS Benke, JL Bragg-Gresham, M Canouil, T Corre, H Grallert, A Isaacs, Z Kutalik, J Lahti, L Marullo, C Marzi, LJ Rasmussen-Torvik, G Rocheleau, R Rueedi, C Scapoli, N Verweij, N Vogelzangs, SM Willems, L Yengo, SJL Bakker, J Beilby, J Hui, E Kajantie, M Müller-Nurasyid, W Rathmann, B Balkau, S Bergmann, JG Eriksson, JC Florez, P Froguel, T Harris, J Hung, AL James, M Kavousi, I Miljkovic, AW Musk, LJ Palmer, A Peters, R Roussel, P van der Harst, CM van Duijn, P Vollenweider, I Barroso, I Prokopenko, J Dupuis, JB Meigs, N Bouatia-Naji
Publication Date: 2019-07-01

Variant appearance in text: rs780094
PubMed Link: 31263163
Variant Present in the following documents:
  • 41598_2019_45823_MOESM2_ESM.xlsx
View BVdb publication page



Genome-Wide Association Study Identifies Loci for Liver Enzyme Concentrations in Mexican Americans: The GUARDIAN Consortium.

Obesity (Silver Spring, Md.)
KA Young, ND Palmer, TE Fingerlin, CD Langefeld, JM Norris, N Wang, AH Xiang, X Guo, AH Williams, YI Chen, KD Taylor, JI Rotter, LJ Raffel, MO Goodarzi, RM Watanabe, LE Wagenknecht
Publication Date: 2019-08

Variant appearance in text: rs780094
PubMed Link: 31219225
Variant Present in the following documents:
  • Main text
  • nihms-1528348.pdf
View BVdb publication page



Insulin Resistance in Children.

Frontiers In Endocrinology
VM Tagi, C Giannini, F Chiarelli
Publication Date: 2019

Variant appearance in text: rs780094
PubMed Link: 31214120
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of maternal circulating 25(OH)D and calcium with birth weight: A mendelian randomisation analysis.

Plos Medicine
WD Thompson, J Tyrrell, MC Borges, RN Beaumont, BA Knight, AR Wood, SM Ring, AT Hattersley, RM Freathy, DA Lawlor
Publication Date: 2019-06

Variant appearance in text: rs780094
PubMed Link: 31211782
Variant Present in the following documents:
  • Main text
View BVdb publication page



No significant association of type 2 diabetes-related genetic risk scores with glycated haemoglobin levels after initiating metformin or sulphonylurea derivatives.

Diabetes, Obesity & Metabolism
DP Martono, HJL Heerspink, E Hak, P Denig, B Wilffert
Publication Date: 2019-10

Variant appearance in text: rs780094
PubMed Link: 31168905
Variant Present in the following documents:
  • Main text
View BVdb publication page



Alternative transcript annotations:

Transcript cDNA Protein Consequence Exon Intron
ENST00000264717.2 c.1423-418T>C - intron_variant - 16/18
ENST00000424318.2 c.853-418T>C - intron_variant - 15/17
NM_001486.4 c.1423-418T>C - intron_variant - 16/18