Development and validation of a multivariable genotype-informed gestational diabetes prediction algorithm for clinical use in the Mexican population: insights into susceptibility mechanisms.
Bmj Open Diabetes Research & Care
Zulueta, Mirella M; Gallardo-Rincón, Héctor H; Martinez-Juarez, Luis Alberto LA; Lomelin-Gascon, Julieta J; Ortega-Montiel, Janinne J; Montoya, Alejandra A; Mendizabal, Leire L; Arregi, Maddi M; Martinez-Martinez, María de Los Angeles MLA; Camarillo Romero, Eneida Del Socorro EDS; Mendieta Zerón, Hugo H; Garduño García, José de Jesús JJ; Simón, Laureano L; Tapia-Conyer, Roberto R
The GCKR-P446L gene variant predisposes to raised blood cholesterol and lower blood glucose in the P446L mouse-a model for GCKR rs1260326.
Molecular Metabolism
Ford, Brian E BE; Chachra, Shruti S SS; Rodgers, Katrina K; Moonira, Tabassum T; Al-Oanzi, Ziad H ZH; Anstee, Quentin M QM; Reeves, Helen L HL; Schattenberg, Jorn M JM; Fairclough, Rebecca J RJ; Smith, David M DM; Tiniakos, Dina D; Agius, Loranne L
Non-Alcoholic Fatty Liver Disease and Vitamin D in the UK Biobank: A Two-Sample Bidirectional Mendelian Randomisation Study.
Nutrients
Zhang, Zixuan Z; Burrows, Kimberley K; Fuller, Harriett H; Speliotes, Elizabeth K EK; Abeysekera, Kushala W M KWM; Thorne, James L JL; Lewis, Sarah J SJ; Zulyniak, Michael A MA; Moore, J Bernadette JB
Genome-Wide Association Studies and fine-mapping of genomic loci for n-3 and n-6 Polyunsaturated Fatty Acids in Hispanic American and African American Cohorts.
Research Square
Yang, Chaojie C; Veenstra, Jenna J; Bartz, Traci T; Pahl, Matthew M; Hallmark, Brian B; Chen, Yii-Der Ida YI; Westra, Jason J; Steffen, Lyn L; Brown, Christopher C; Siscovick, David D; Tsai, Michael M; Wood, Alexis A; Rich, Stephen S; Smith, Caren C; O'Connor, Timothy T; Mozaffarian, Dariush D; Grant, Struan S; Chilton, Floyd F; Tintle, Nathan N; Lemaitre, Rozenn R; Manichaikul, Ani A
Association of Inherited Genetic Factors With Drug-Induced Hepatic Damage Among Children With Acute Lymphoblastic Leukemia.
Jama Network Open
Yang, Wenjian W; Karol, Seth E SE; Hoshitsuki, Keito K; Lee, Shawn S; Larsen, Eric C EC; Winick, Naomi N; Carroll, William L WL; Loh, Mignon L ML; Raetz, Elizabeth A EA; Hunger, Stephen P SP; Winter, Stuart S SS; Dunsmore, Kimberly P KP; Devidas, Meenakshi M; Relling, Mary V MV; Yang, Jun J JJ
Aggregation of Genome-Wide Association Data from FinnGen and UK Biobank Replicates Multiple Risk Loci for Pregnancy Complications.
Genes
Changalidis, Anton I AI; Maksiutenko, Evgeniia M EM; Barbitoff, Yury A YA; Tkachenko, Alexander A AA; Vashukova, Elena S ES; Pachuliia, Olga V OV; Nasykhova, Yulia A YA; Glotov, Andrey S AS
Genetic variants for prediction of gestational diabetes mellitus and modulation of susceptibility by a nutritional intervention based on a Mediterranean diet.
Frontiers In Endocrinology
Ramos-Levi, Ana A; Barabash, Ana A; Valerio, Johanna J; García de la Torre, Nuria N; Mendizabal, Leire L; Zulueta, Mirella M; de Miguel, Maria Paz MP; Diaz, Angel A; Duran, Alejandra A; Familiar, Cristina C; Jimenez, Inés I; Del Valle, Laura L; Melero, Veronica V; Moraga, Inmaculada I; Herraiz, Miguel A MA; Torrejon, María José MJ; Arregi, Maddi M; Simón, Laureano L; Rubio, Miguel A MA; Calle-Pascual, Alfonso L AL
Potential Therapeutic Implication of Herbal Medicine in Mitochondria-Mediated Oxidative Stress-Related Liver Diseases.
Antioxidants (Basel, Switzerland)
Park, Moon Nyeo MN; Rahman, Md Ataur MA; Rahman, Md Hasanur MH; Kim, Jong Woo JW; Choi, Min M; Kim, Jeong Woo JW; Choi, Jinwon J; Moon, Myunghan M; Ahmed, Kazi Rejvee KR; Kim, Bonglee B
Additive genetic effect of GCKR, G6PC2, and SLC30A8 variants on fasting glucose levels and risk of type 2 diabetes.
Plos One
Chen, Guanjie G; Shriner, Daniel D; Zhang, Jianhua J; Zhou, Jie J; Adikaram, Poorni P; Doumatey, Ayo P AP; Bentley, Amy R AR; Adeyemo, Adebowale A; Rotimi, Charles N CN
Publication Date: 2022
Variant appearance in text: GCKR: 1423-418T>C; rs780094
Evaluating machine learning-powered classification algorithms which utilize variants in the GCKR gene to predict metabolic syndrome: Tehran Cardio-metabolic Genetics Study.
Journal Of Translational Medicine
Akbarzadeh, Mahdi M; Alipour, Nadia N; Moheimani, Hamed H; Zahedi, Asieh Sadat AS; Hosseini-Esfahani, Firoozeh F; Lanjanian, Hossein H; Azizi, Fereidoun F; Daneshpour, Maryam S MS
Dihydroceramide- and ceramide-profiling provides insights into human cardiometabolic disease etiology.
Nature Communications
Wittenbecher, C C; Cuadrat, R R; Johnston, L L; Eichelmann, F F; Jäger, S S; Kuxhaus, O O; Prada, M M; Del Greco M, F F; Hicks, A A AA; Hoffman, P P; Krumsiek, J J; Hu, F B FB; Schulze, M B MB
Factors That Predict the Progression of Non-alcoholic Fatty Liver Disease (NAFLD).
Cureus
Parameswaran, Madhangi M; Hasan, Hamzah A HA; Sadeque, Jafor J; Jhaveri, Sharan S; Avanthika, Chaithanya C; Arisoyin, Abimbola E AE; Dhanani, Maulik B MB; Rath, Swaroopa M SM
Identification of 90 NAFLD GWAS loci and establishment of NAFLD PRS and causal role of NAFLD in coronary artery disease.
Hgg Advances
Miao, Zong Z; Garske, Kristina M KM; Pan, David Z DZ; Koka, Amogha A; Kaminska, Dorota D; Männistö, Ville V; Sinsheimer, Janet S JS; Pihlajamäki, Jussi J; Pajukanta, Päivi P
Genetic assessment of hyperuricemia and gout in Asian, Native Hawaiian, and Pacific Islander subgroups of pregnant women: biospecimens repository cross-sectional study.
Bmc Rheumatology
Alghubayshi, Ali A; Edelman, Alison A; Alrajeh, Khalifa K; Roman, Youssef Y
Genetic assessment of hyperuricemia and gout in Asian, Native Hawaiian, and Pacific Islander subgroups of pregnant women: biospecimens repository cross-sectional study.
Bmc Rheumatology
Alghubayshi, Ali A; Edelman, Alison A; Alrajeh, Khalifa K; Roman, Youssef Y