Circulating tumor DNA reveals mechanisms of lorlatinib resistance in patients with relapsed/refractory ALK-driven neuroblastoma.
Nature Communications
Berko, Esther R ER; Witek, Gabriela M GM; Matkar, Smita S; Petrova, Zaritza O ZO; Wu, Megan A MA; Smith, Courtney M CM; Daniels, Alex A; Kalna, Joshua J; Kennedy, Annie A; Gostuski, Ivan I; Casey, Colleen C; Krytska, Kateryna K; Gerelus, Mark M; Pavlick, Dean D; Ghazarian, Susan S; Park, Julie R JR; Marachelian, Araz A; Maris, John M JM; Goldsmith, Kelly C KC; Radhakrishnan, Ravi R; Lemmon, Mark A MA; Mossé, Yaël P YP
The Landscape of ALK-Rearranged Non-Small Cell Lung Cancer: A Comprehensive Review of Clinicopathologic, Genomic Characteristics, and Therapeutic Perspectives.
DNA methylome and single-cell transcriptome analyses reveal CDA as a potential druggable target for ALK inhibitor-resistant lung cancer therapy.
Experimental & Molecular Medicine
Heo, Haejeong H; Kim, Jong-Hwan JH; Lim, Hyun Jung HJ; Kim, Jeong-Hwan JH; Kim, Miso M; Koh, Jaemoon J; Im, Joo-Young JY; Kim, Bo-Kyung BK; Won, Misun M; Park, Ji-Hwan JH; Shin, Yang-Ji YJ; Yun, Mi Ran MR; Cho, Byoung Chul BC; Kim, Yong Sung YS; Kim, Seon-Young SY; Kim, Mirang M
Pugh, Trevor J TJ; Bell, Jonathan L JL; Bruce, Jeff P JP; Doherty, Gary J GJ; Galvin, Matthew M; Green, Michelle F MF; Hunter-Zinck, Haley H; Kumari, Priti P; Lenoue-Newton, Michele L ML; Li, Marilyn M MM; Lindsay, James J; Mazor, Tali T; Ovalle, Andrea A; Sammut, Stephen-John SJ; Schultz, Nikolaus N; Yu, Thomas V TV; Sweeney, Shawn M SM; Bernard, Brady B; ,
Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.
Frontiers In Oncology
Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J
The Change in Paradigm for NSCLC Patients with EML4-ALK Translocation.
International Journal Of Molecular Sciences
Bearz, Alessandra A; De Carlo, Elisa E; Del Conte, Alessandro A; Spina, Michele M; Da Ros, Valentina V; Bertoli, Elisa E; Revelant, Alberto A; Stanzione, Brigida B; Tirelli, Umberto U
The Impact of Comprehensive Genomic Profiling (CGP) on the Decision-Making Process in the Treatment of ALK-Rearranged Advanced Non-Small Cell Lung Cancer (aNSCLC) After Failure of 2nd/3rd-Generation ALK Tyrosine Kinase Inhibitors (TKIs).
Frontiers In Oncology
Raphael, Ari A; Onn, Amir A; Holtzman, Liran L; Dudnik, Julia J; Urban, Damien D; Kian, Waleed W; Cohen, Aharon Y AY; Moskovitz, Mor M; Zer, Alona A; Bar, Jair J; Rabinovich, Natalie Maimon NM; Grynberg, Shirly S; Oedegaard, Cecilie C; Agbarya, Abed A; Peled, Nir N; Shochat, Tzippy T; Dudnik, Elizabeth E
Nanomedicine Strategies for Management of Drug Resistance in Lung Cancer.
International Journal Of Molecular Sciences
Haider, Mohamed M; Elsherbeny, Amr A; Pittalà, Valeria V; Consoli, Valeria V; Alghamdi, Maha Ali MA; Hussain, Zahid Z; Khoder, Ghalia G; Greish, Khaled K
Nanomedicine Strategies for Management of Drug Resistance in Lung Cancer.
International Journal Of Molecular Sciences
Haider, Mohamed M; Elsherbeny, Amr A; Pittalà, Valeria V; Consoli, Valeria V; Alghamdi, Maha Ali MA; Hussain, Zahid Z; Khoder, Ghalia G; Greish, Khaled K