ALK c.3745G>T ;(p.D1249Y)

Variant ID: 2-29432743-C-A

NM_004304.4(ALK):c.3745G>T;(p.D1249Y)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Secondary Resistant Mutations to Small Molecule Inhibitors in Cancer Cells.

Cancers
Hamid, Abdulaziz B AB; Petreaca, Ruben C RC
Publication Date: 2020-04-09

Variant appearance in text: ALK: D1249Y
PubMed Link: 32283832
Variant Present in the following documents:
  • cancers-12-00927-s001.pdf
View BVdb publication page



Structure and energy based quantitative missense variant effect analysis provides insights into drug resistance mechanisms of anaplastic lymphoma kinase mutations.

Scientific Reports
Li, Jianzong J; Huang, Yue Y; Wu, Miaomiao M; Wu, Chuanfang C; Li, Xin X; Bao, Jinku J
Publication Date: 2018-07-13

Variant appearance in text: ALK: D1249Y
PubMed Link: 30006516
Variant Present in the following documents:
  • 41598_2018_28752_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page