ALK c.3695A>G ;(p.D1232G)

Variant ID: 2-29436898-T-C

NM_004304.4(ALK):c.3695A>G;(p.D1232G)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


A full-proteome, interaction-specific characterization of mutational hotspots across human cancers.

Genome Research
Chen, Siwei S; Liu, Yuan Y; Zhang, Yingying Y; Wierbowski, Shayne D SD; Lipkin, Steven M SM; Wei, Xiaomu X; Yu, Haiyuan H
Publication Date: 2022-01

Variant appearance in text: ALK: D1232G
PubMed Link: 34963661
Variant Present in the following documents:
  • supp_gr.275437.121_Supplementary_Table_1.xlsx, sheet 3
View BVdb publication page



NPM/ALK mutants resistant to ASP3026 display variable sensitivity to alternative ALK inhibitors but succumb to the novel compound PF-06463922.

Oncotarget
Mologni, Luca L; Ceccon, Monica M; Pirola, Alessandra A; Chiriano, Gianpaolo G; Piazza, Rocco R; Scapozza, Leonardo L; Gambacorti-Passerini, Carlo C
Publication Date: 2015-03-20

Variant appearance in text: ALK: D1232G
PubMed Link: 25749034
Variant Present in the following documents:
  • oncotarget-06-5720-s001.pdf
View BVdb publication page