Pancreatic Cancer-Related Mutational Burden Is Not Increased in a Patient Cohort With Clinically Severe Chronic Pancreatitis.
Clinical And Translational Gastroenterology
Cowan, Robert W RW; Pratt, Erica D ED; Kang, Jin Muk JM; Zhao, Jun J; Wilhelm, Joshua J JJ; Abdulla, Muhamad M; Qiao, Edmund M EM; Brennan, Luke P LP; Ulintz, Peter J PJ; Bellin, Melena D MD; Rhim, Andrew D AD
Publication Date: 2021-11-18
Variant appearance in text: ALK: 3602G>A; Gly1201Glu
Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.
Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Oncogenic ALK drives tumorigenesis in cutaneous squamous cell carcinoma.
Life Science Alliance
Gualandi, Marco M; Iorio, Maria M; Engeler, Olivia O; Serra-Roma, André A; Gasparre, Giuseppe G; Schulte, Johannes H JH; Hohl, Daniel D; Shakhova, Olga O
Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.
Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Repotrectinib (TPX-0005), effectively reduces growth of ALK driven neuroblastoma cells.
Scientific Reports
Cervantes-Madrid, Diana D; Szydzik, Joanna J; Lind, Dan Emil DE; Borenäs, Marcus M; Bemark, Mats M; Cui, Jean J; Palmer, Ruth Helen RH; Hallberg, Bengt B
Unique mutation patterns in anaplastic thyroid cancer identified by comprehensive genomic profiling.
Head & Neck
Khan, Saad A SA; Ci, Bo B; Xie, Yang Y; Gerber, David E DE; Beg, Muhammad S MS; Sherman, Steven I SI; Cabanillas, Maria E ME; Busaidy, Naifa L NL; Burtness, Barbara A BA; Heilmann, Andreas M AM; Bailey, Mark M; Ross, Jeffrey S JS; Sher, David J DJ; Ali, Siraj M SM
Structure and energy based quantitative missense variant effect analysis provides insights into drug resistance mechanisms of anaplastic lymphoma kinase mutations.
Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma.
Nature Communications
Lauss, Martin M; Donia, Marco M; Harbst, Katja K; Andersen, Rikke R; Mitra, Shamik S; Rosengren, Frida F; Salim, Maryem M; Vallon-Christersson, Johan J; Törngren, Therese T; Kvist, Anders A; Ringnér, Markus M; Svane, Inge Marie IM; Jönsson, Göran G
Performance of a RT-PCR Assay in Comparison to FISH and Immunohistochemistry for the Detection of ALK in Non-Small Cell Lung Cancer.
Cancers
Hout, David R DR; Schweitzer, Brock L BL; Lawrence, Kasey K; Morris, Stephan W SW; Tucker, Tracy T; Mazzola, Rosetta R; Skelton, Rachel R; McMahon, Frank F; Handshoe, John J; Lesperance, Mary M; Karsan, Aly A; Saltman, David L DL
Holla, Vijaykumar R VR; Elamin, Yasir Y YY; Bailey, Ann Marie AM; Johnson, Amber M AM; Litzenburger, Beate C BC; Khotskaya, Yekaterina B YB; Sanchez, Nora S NS; Zeng, Jia J; Shufean, Md Abu MA; Shaw, Kenna R KR; Mendelsohn, John J; Mills, Gordon B GB; Meric-Bernstam, Funda F; Simon, George R GR