ALK c.3521T>G ;(p.F1174C)

Variant ID: 2-29443696-A-C

NM_004304.4(ALK):c.3521T>G;(p.F1174C)

This variant was identified in 196 publications

View GRCh38 version.




Publications:


Biology and impact of lineage plasticity in ALK-positive NSCLC: a narrative review.

Translational Lung Cancer Research
Meador, Catherine B CB; Piotrowska, Zofia Z
Publication Date: 2023-04-28

Variant appearance in text: ALK: F1174C
PubMed Link: 37197622
Variant Present in the following documents:
  • Main text
  • tlcr-12-04-837.pdf
View BVdb publication page



EML4-ALK biology and drug resistance in Non-Small Cell Lung Cancer: a new phase of discoveries.

Molecular Oncology
Elshatlawy, Mariam M; Sampson, Josephina J; Clarke, Katy K; Bayliss, Richard R
Publication Date: 2023-05-07

Variant appearance in text: ALK: F1174C
PubMed Link: 37149843
Variant Present in the following documents:
  • Main text
  • MOL2-17-950.pdf
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Circulating tumor DNA reveals mechanisms of lorlatinib resistance in patients with relapsed/refractory ALK-driven neuroblastoma.

Nature Communications
Berko, Esther R ER; Witek, Gabriela M GM; Matkar, Smita S; Petrova, Zaritza O ZO; Wu, Megan A MA; Smith, Courtney M CM; Daniels, Alex A; Kalna, Joshua J; Kennedy, Annie A; Gostuski, Ivan I; Casey, Colleen C; Krytska, Kateryna K; Gerelus, Mark M; Pavlick, Dean D; Ghazarian, Susan S; Park, Julie R JR; Marachelian, Araz A; Maris, John M JM; Goldsmith, Kelly C KC; Radhakrishnan, Ravi R; Lemmon, Mark A MA; Mossé, Yaël P YP
Publication Date: 2023-05-05

Variant appearance in text: ALK: F1174C
PubMed Link: 37147298
Variant Present in the following documents:
  • Main text
  • 41467_2023_38195_MOESM3_ESM.xlsx, sheet 1
  • 41467_2023_Article_38195.pdf
  • 41467_2023_38195_MOESM3_ESM.xlsx, sheet 2
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Strategies to overcome resistance to ALK inhibitors in non-small cell lung cancer: a narrative review.

Translational Lung Cancer Research
Desai, Aakash A; Lovly, Christine M CM
Publication Date: 2023-03-31

Variant appearance in text: ALK: F1174C
PubMed Link: 37057106
Variant Present in the following documents:
  • Main text
  • tlcr-12-03-615.pdf
View BVdb publication page



Iruplinalkib (WX‑0593), a novel ALK/ROS1 inhibitor, overcomes crizotinib resistance in preclinical models for non-small cell lung cancer.

Investigational New Drugs
Yang, Yingying Y; Zheng, Qingmei Q; Wang, Xinmei X; Zhao, Shuyong S; Huang, Wenshu W; Jia, Linchao L; Ma, Cuicui C; Liu, Shicong S; Zhang, Yongpeng Y; Xin, Qianqian Q; Sun, Yan Y; Zheng, Shansong S
Publication Date: 2023-04-10

Variant appearance in text: ALK: F1174C
PubMed Link: 37036582
Variant Present in the following documents:
  • Main text
  • 10637_2023_Article_1350.pdf
View BVdb publication page



Lorlatinib with or without chemotherapy in ALK-driven refractory/relapsed neuroblastoma: phase 1 trial results.

Nature Medicine
Goldsmith, Kelly C KC; Park, Julie R JR; Kayser, Kimberly K; Malvar, Jemily J; Chi, Yueh-Yun YY; Groshen, Susan G SG; Villablanca, Judith G JG; Krytska, Kateryna K; Lai, Lillian M LM; Acharya, Patricia T PT; Goodarzian, Fariba F; Pawel, Bruce B; Shimada, Hiroyuki H; Ghazarian, Susan S; States, Lisa L; Marshall, Lynley L; Chesler, Louis L; Granger, Meaghan M; Desai, Ami V AV; Mody, Rajen R; Morgenstern, Daniel A DA; Shusterman, Suzanne S; Macy, Margaret E ME; Pinto, Navin N; Schleiermacher, Gudrun G; Vo, Kieuhoa K; Thurm, Holger C HC; Chen, Joseph J; Liyanage, Marlon M; Peltz, Gerson G; Matthay, Katherine K KK; Berko, Esther R ER; Maris, John M JM; Marachelian, Araz A; Mossé, Yael P YP
Publication Date: 2023-04-03

Variant appearance in text: ALK: F1174C
PubMed Link: 37012551
Variant Present in the following documents:
  • Main text
  • 41591_2023_Article_2297.pdf
View BVdb publication page



Recent progress in targeted therapy for non-small cell lung cancer.

Frontiers In Pharmacology
Xiao, Yanxia Y; Liu, Pu P; Wei, Jie J; Zhang, Xin X; Guo, Jun J; Lin, Yajun Y
Publication Date: 2023

Variant appearance in text: ALK: F1174C
PubMed Link: 36909198
Variant Present in the following documents:
  • Main text
  • fphar-14-1125547.pdf
View BVdb publication page



Genomic ALK alterations in primary and relapsed neuroblastoma.

British Journal Of Cancer
Rosswog, Carolina C; Fassunke, Jana J; Ernst, Angela A; Schömig-Markiefka, Birgid B; Merkelbach-Bruse, Sabine S; Bartenhagen, Christoph C; Cartolano, Maria M; Ackermann, Sandra S; Theissen, Jessica J; Blattner-Johnson, Mirjam M; Jones, Barbara B; Schramm, Kathrin K; Altmüller, Janine J; Nürnberg, Peter P; Ortmann, Monika M; Berthold, Frank F; Peifer, Martin M; Büttner, Reinhard R; Westermann, Frank F; Schulte, Johannes H JH; Simon, Thorsten T; Hero, Barbara B; Fischer, Matthias M
Publication Date: 2023-02-17

Variant appearance in text: ALK: F1174C
PubMed Link: 36807339
Variant Present in the following documents:
  • Main text
  • 41416_2023_Article_2208.pdf
  • 41416_2023_2208_MOESM1_ESM.pdf
View BVdb publication page



Ensartinib in advanced ALK-positive non-small cell lung cancer: a multicenter, open-label, two-staged, phase 1 trial.

Journal Of Thoracic Disease
Ma, Yuxiang Y; Pan, Hui H; Liu, Yu Y; Zhang, Yang Y; Hong, Shaodong S; Huang, Jianjin J; Weng, Shanshan S; Yang, Yunpeng Y; Fang, Wenfeng W; Huang, Yan Y; Xiao, Shanshan S; Wang, Tao T; Ding, Lieming L; Cui, Lingling L; Zhang, Li L; Zhao, Hongyun H
Publication Date: 2022-12

Variant appearance in text: ALK: F1174C
PubMed Link: 36647478
Variant Present in the following documents:
  • Main text
  • jtd-14-12-4751.pdf
View BVdb publication page



Combination Therapies Targeting Alk-Aberrant Neuroblastoma in Preclinical Models.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Tucker, Elizabeth R ER; Jiménez, Irene I; Chen, Lindi L; Bellini, Angela A; Gorrini, Chiara C; Calton, Elizabeth E; Gao, Qiong Q; Che, Harvey H; Poon, Evon E; Jamin, Yann Y; Martins Da Costa, Barbara B; Barker, Karen K; Shrestha, Sumana S; Hutchinson, J Ciaran JC; Dhariwal, Simran S; Goodman, Angharad A; Del Nery, Elaine E; Gestraud, Pierre P; Bhalshankar, Jaydutt J; Iddir, Yasmine Y; Saberi-Ansari, Elnaz E; Saint-Charles, Alexandra A; Geoerger, Birgit B; Marques Da Costa, Maria Eugenia ME; Pierre-Eugene, Cecile C; Janoueix-Lerosey, Isabelle I; Decaudin, Didier D; Némati, Fariba F; Carcaboso, Angel M AM; Surdez, Didier D; Delattre, Olivier O; George, Sally L SL; Chesler, Louis L; Tweddle, Deborah A DA; Schleiermacher, Gudrun G
Publication Date: 2023-01-05

Variant appearance in text: ALK: F1174C
PubMed Link: 36602782
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genomic Profiling of Sarcomas: A Promising Weapon in the Therapeutic Arsenal.

International Journal Of Molecular Sciences
Lopes-Brás, Raquel R; Lopez-Presa, Dolores D; Esperança-Martins, Miguel M; Melo-Alvim, Cecília C; Gallego, Lina L; Costa, Luís L; Fernandes, Isabel I
Publication Date: 2022-11-17

Variant appearance in text: ALK: F1174C
PubMed Link: 36430703
Variant Present in the following documents:
  • ijms-23-14227.pdf
View BVdb publication page



Emerging Role of YAP and the Hippo Pathway in Prostate Cancer.

Biomedicines
Koinis, Filippos F; Chantzara, Evangelia E; Samarinas, Michael M; Xagara, Anastasia A; Kratiras, Zisis Z; Leontopoulou, Vasiliki V; Kotsakis, Athanasios A
Publication Date: 2022-11-07

Variant appearance in text: ALK: F1174C
PubMed Link: 36359354
Variant Present in the following documents:
  • Main text
  • biomedicines-10-02834.pdf
View BVdb publication page



The Landscape of ALK-Rearranged Non-Small Cell Lung Cancer: A Comprehensive Review of Clinicopathologic, Genomic Characteristics, and Therapeutic Perspectives.

Cancers
Cognigni, Valeria V; Pecci, Federica F; Lupi, Alessio A; Pinterpe, Giada G; De Filippis, Chiara C; Felicetti, Cristiano C; Cantini, Luca L; Berardi, Rossana R
Publication Date: 2022-09-29

Variant appearance in text: ALK: F1174C
PubMed Link: 36230686
Variant Present in the following documents:
  • Main text
  • cancers-14-04765.pdf
View BVdb publication page



Molecular targeted therapy for anticancer treatment.

Experimental & Molecular Medicine
Min, Hye-Young HY; Lee, Ho-Young HY
Publication Date: 2022-10

Variant appearance in text: ALK: F1174C
PubMed Link: 36224343
Variant Present in the following documents:
  • Main text
  • 12276_2022_Article_864.pdf
View BVdb publication page



Durable clinical response to ALK tyrosine kinase inhibitors in ALK-rearranged non-small cell lung cancer: a case report.

Translational Cancer Research
Hu, Han H; Dai, Hui H; Ding, Liren L
Publication Date: 2022-08

Variant appearance in text: ALK: F1174C
PubMed Link: 36093526
Variant Present in the following documents:
  • Main text
  • tcr-11-08-2967.pdf
View BVdb publication page



Interplay of Developmental Hippo-Notch Signaling Pathways with the DNA Damage Response in Prostate Cancer.

Cells
Mourkioti, Ioanna I; Angelopoulou, Andriani A; Belogiannis, Konstantinos K; Lagopati, Nefeli N; Potamianos, Spyridon S; Kyrodimos, Efthymios E; Gorgoulis, Vassilis V; Papaspyropoulos, Angelos A
Publication Date: 2022-08-07

Variant appearance in text: ALK: F1174C
PubMed Link: 35954292
Variant Present in the following documents:
  • cells-11-02449.pdf
View BVdb publication page



Fibroblast growth factor receptor 3 overexpression mediates ALK inhibitor resistance in ALK-rearranged non-small cell lung cancer.

Cancer Science
Sakashita, Takuya T; Yanagitani, Noriko N; Koike, Sumie S; Low, Siew-Kee SK; Takagi, Satoshi S; Baba, Satoko S; Takeuchi, Kengo K; Nishio, Makoto M; Fujita, Naoya N; Katayama, Ryohei R
Publication Date: 2022-11

Variant appearance in text: ALK: F1174C
PubMed Link: 35950895
Variant Present in the following documents:
  • CAS-113-3888-s002.pdf
  • CAS-113-3888.pdf
View BVdb publication page



AACR Project GENIE: 100,000 Cases and Beyond.

Cancer Discovery
Pugh, Trevor J TJ; Bell, Jonathan L JL; Bruce, Jeff P JP; Doherty, Gary J GJ; Galvin, Matthew M; Green, Michelle F MF; Hunter-Zinck, Haley H; Kumari, Priti P; Lenoue-Newton, Michele L ML; Li, Marilyn M MM; Lindsay, James J; Mazor, Tali T; Ovalle, Andrea A; Sammut, Stephen-John SJ; Schultz, Nikolaus N; Yu, Thomas V TV; Sweeney, Shawn M SM; Bernard, Brady B; ,
Publication Date: 2022-09-02

Variant appearance in text: ALK: F1174C
PubMed Link: 35819403
Variant Present in the following documents:
  • cd-21-1547_supplementary_table_1_suppst1.xlsx, sheet 1
View BVdb publication page



Small-cell carcinoma of the prostate with negative CD56, NSE, Syn, and CgA indicators: A case report.

World Journal Of Clinical Cases
Shi, Hong-Jin HJ; Fan, Zhi-Nan ZN; Zhang, Jin-Song JS; Xiong, Bo-Bo BB; Wang, Hai-Feng HF; Wang, Jian-Song JS
Publication Date: 2022-02-16

Variant appearance in text: ALK: F1174C
PubMed Link: 35211603
Variant Present in the following documents:
  • WJCC-10-1630.pdf
View BVdb publication page



Prospective analysis of liquid biopsies of advanced non-small cell lung cancer patients after progression to targeted therapies using GeneReader NGS platform.

Translational Cancer Research
Mayo de Las Casas, Clara C; Garzón-Ibañez, Mónica M; Jordana-Ariza, Núria N; Viteri-Ramírez, Santiago S; Moya-Horno, Irene I; Karachaliou, Niki N; Yeste, Zaira Z; Campos, Raquel R; Villatoro, Sergi S; Balada-Bel, Ariadna A; García-Peláez, Beatriz B; Reguart, Noemí N; Teixidó, Cristina C; Jantús, Eloisa E; Calabuig, Silvia S; Aguado, Cristina C; Giménez-Capitán, Ana A; Román-Lladó, Ruth R; Pérez-Rosado, Ana A; Catalán, Maria José MJ; Bertrán-Alamillo, Jordi J; García-Román, Silvia S; Rodriguez, Sonia S; Alonso, Lidia L; Aldeguer, Erika E; Martínez-Bueno, Alejandro A; González-Cao, Maria M; Aguilar Hernandez, Andrés A; Garcia-Mosquera, Juan J; de Los Llanos Gil, Maria M; Fernandez, Manuel M; Rosell, Rafael R; Molina-Vila, Miguel Ángel MÁ
Publication Date: 2019-01

Variant appearance in text: ALK: F1174C
PubMed Link: 35117060
Variant Present in the following documents:
  • Main text
View BVdb publication page



Investigation of PALB2 Mutation and Correlation With Immunotherapy Biomarker in Chinese Non-Small Cell Lung Cancer Patients.

Frontiers In Oncology
Zhang, Jiexia J; Tang, Shuangfeng S; Zhang, Chunning C; Li, Mingyao M; Zheng, Yating Y; Hu, Xue X; Huang, Mengli M; Cheng, Xiangyang X
Publication Date: 2021

Variant appearance in text: ALK: 3521T>G; F1174C
PubMed Link: 35087742
Variant Present in the following documents:
  • Table_2.xlsx, sheet 1
View BVdb publication page



Relevance of Circulating Tumor Cells as Predictive Markers for Cancer Incidence and Relapse.

Pharmaceuticals (Basel, Switzerland)
Chelakkot, Chaithanya C; Yang, Hobin H; Shin, Young Kee YK
Publication Date: 2022-01-06

Variant appearance in text: ALK: F1174C
PubMed Link: 35056131
Variant Present in the following documents:
  • pharmaceuticals-15-00075.pdf
View BVdb publication page



Relevance of Circulating Tumor Cells as Predictive Markers for Cancer Incidence and Relapse.

Pharmaceuticals (Basel, Switzerland)
Chelakkot, Chaithanya C; Yang, Hobin H; Shin, Young Kee YK
Publication Date: 2022-01-06

Variant appearance in text: ALK: F1174C
PubMed Link: 35056131
Variant Present in the following documents:
  • pharmaceuticals-15-00075.pdf
View BVdb publication page



Deciphering the Mechanism of Gilteritinib Overcoming Lorlatinib Resistance to the Double Mutant I1171N/F1174I in Anaplastic Lymphoma Kinase.

Frontiers In Cell And Developmental Biology
Liang, Shuai S; Wang, Qing Q; Qi, Xuesen X; Liu, Yudi Y; Li, Guozhen G; Lu, Shaoyong S; Mou, Linkai L; Chen, Xiangyu X
Publication Date: 2021

Variant appearance in text: ALK: F1174C
PubMed Link: 35004700
Variant Present in the following documents:
  • Main text
View BVdb publication page



The value of cell-free circulating tumour DNA profiling in advanced non-small cell lung cancer (NSCLC) management.

Cancer Cell International
Fernandes, Maria Gabriela O MGO; Cruz-Martins, Natália N; Machado, José Carlos JC; Costa, José Luís JL; Hespanhol, Venceslau V
Publication Date: 2021-12-16

Variant appearance in text: ALK: F1174C
PubMed Link: 34915883
Variant Present in the following documents:
  • Main text
  • 12935_2021_Article_2382.pdf
View BVdb publication page



The value of cell-free circulating tumour DNA profiling in advanced non-small cell lung cancer (NSCLC) management.

Cancer Cell International
Fernandes, Maria Gabriela O MGO; Cruz-Martins, Natália N; Machado, José Carlos JC; Costa, José Luís JL; Hespanhol, Venceslau V
Publication Date: 2021-12-16

Variant appearance in text: ALK: F1174C
PubMed Link: 34915883
Variant Present in the following documents:
  • Main text
  • 12935_2021_Article_2382.pdf
View BVdb publication page



Resistance to Targeted Agents Used to Treat Paediatric ALK-Positive ALCL.

Cancers
Hare, Lucy L; Burke, G A Amos GAA; Turner, Suzanne D SD
Publication Date: 2021-11-29

Variant appearance in text: ALK: F1174C
PubMed Link: 34885113
Variant Present in the following documents:
  • Main text
View BVdb publication page



Resistance to Targeted Agents Used to Treat Paediatric ALK-Positive ALCL.

Cancers
Hare, Lucy L; Burke, G A Amos GAA; Turner, Suzanne D SD
Publication Date: 2021-11-29

Variant appearance in text: ALK: F1174C
PubMed Link: 34885113
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genomic and experimental evidence that ALKATI does not predict single agent sensitivity to ALK inhibitors.

Iscience
Inam, Haider H; Sokirniy, Ivan I; Rao, Yiyun Y; Shah, Anushka A; Naeemikia, Farnaz F; O'Brien, Edward E; Dong, Cheng C; McCandlish, David M DM; Pritchard, Justin R JR
Publication Date: 2021-11-19

Variant appearance in text: ALK: F1174C
PubMed Link: 34825133
Variant Present in the following documents:
  • Main text
  • mmc1.pdf
  • main.pdf
View BVdb publication page



Defining Pathological Activities of ALK in Neuroblastoma, a Neural Crest-Derived Cancer.

International Journal Of Molecular Sciences
Wulf, Anna M AM; Moreno, Marcela M MM; Paka, Chloé C; Rampasekova, Alexandra A; Liu, Karen J KJ
Publication Date: 2021-10-29

Variant appearance in text: ALK: F1174C
PubMed Link: 34769149
Variant Present in the following documents:
  • Main text
View BVdb publication page



Two novel strategies to overcome the resistance to ALK tyrosine kinase inhibitor drugs: Macrocyclic inhibitors and proteolysis-targeting chimeras.

Medcomm
Song, Xiaoling X; Zhong, Hui H; Qu, Xiaojuan X; Yang, Linsong L; Jiang, Biao B
Publication Date: 2021-09

Variant appearance in text: ALK: F1174C
PubMed Link: 34766150
Variant Present in the following documents:
  • Main text
  • MCO2-2-341.pdf
View BVdb publication page



Long-Term Survival After Salvage Thoracic Surgery on a Patient with ALK-Rearranged Metastatic Lung Adenocarcinoma After Progression on Targeted Therapy.

Oncotargets And Therapy
Ren, Kangqi K; Ding, Guanggui G; Xie, Shuying S; Yang, Lin L
Publication Date: 2021

Variant appearance in text: ALK: F1174C
PubMed Link: 34754197
Variant Present in the following documents:
  • Main text
View BVdb publication page



New Advances in Liquid Biopsy Technologies for Anaplastic Lymphoma Kinase (ALK)-Positive Cancer.

Cancers
Villa, Matteo M; Sharma, Geeta G GG; Manfroni, Chiara C; Cortinovis, Diego D; Mologni, Luca L
Publication Date: 2021-10-14

Variant appearance in text: ALK: F1174C
PubMed Link: 34680298
Variant Present in the following documents:
  • Main text
View BVdb publication page



The Resistance Mechanisms and Treatment Strategies for ALK-Rearranged Non-Small Cell Lung Cancer.

Frontiers In Oncology
Pan, Yue Y; Deng, Chao C; Qiu, Zhenhua Z; Cao, Chenghui C; Wu, Fang F
Publication Date: 2021

Variant appearance in text: ALK: F1174C
PubMed Link: 34660278
Variant Present in the following documents:
  • Main text
  • fonc-11-713530.pdf
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: ALK: F1174C
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



A Novel Sequentially Evolved EML4-ALK Variant 3 G1202R/S1206Y Double Mutation In Cis Confers Resistance to Lorlatinib: A Brief Report and Literature Review.

Jto Clinical And Research Reports
Zhu, Viola W VW; Nagasaka, Misako M; Madison, Russell R; Schrock, Alexa B AB; Cui, Jean J; Ou, Sai-Hong Ignatius SI
Publication Date: 2021-01

Variant appearance in text: ALK: F1174C
PubMed Link: 34589977
Variant Present in the following documents:
  • Main text
View BVdb publication page



Therapeutic Targeting of the Anaplastic Lymphoma Kinase (ALK) in Neuroblastoma-A Comprehensive Update.

Pharmaceutics
Brenner, Annette K AK; Gunnes, Maria W MW
Publication Date: 2021-09-08

Variant appearance in text: ALK: F1174C
PubMed Link: 34575503
Variant Present in the following documents:
  • Main text
  • pharmaceutics-13-01427.pdf
View BVdb publication page



A narrative review of tumor heterogeneity and challenges to tumor drug therapy.

Annals Of Translational Medicine
Zhu, Liang L; Jiang, Minlin M; Wang, Hao H; Sun, Hui H; Zhu, Jun J; Zhao, Wencheng W; Fang, Qiyu Q; Yu, Jia J; Chen, Peixin P; Wu, Shengyu S; Zheng, Zixuan Z; He, Yayi Y
Publication Date: 2021-08

Variant appearance in text: ALK: F1174C
PubMed Link: 34532488
Variant Present in the following documents:
  • Main text
  • atm-09-16-1351.pdf
View BVdb publication page



Kinase fusion-related thyroid carcinomas: distinct pathologic entities with evolving diagnostic implications.

Diagnostic Histopathology (Oxford, England)
Chu, Ying-Hsia YH; Sadow, Peter M PM
Publication Date: 2021-06

Variant appearance in text: ALK: F1174C
PubMed Link: 34484420
Variant Present in the following documents:
  • Main text
View BVdb publication page



Clinical Utility of Liquid Biopsy-Based Actionable Mutations Detected via ddPCR.

Biomedicines
Palacín-Aliana, Irina I; García-Romero, Noemí N; Asensi-Puig, Adrià A; Carrión-Navarro, Josefa J; González-Rumayor, Víctor V; Ayuso-Sacido, Ángel Á
Publication Date: 2021-07-28

Variant appearance in text: ALK: F1174C
PubMed Link: 34440110
Variant Present in the following documents:
  • Main text
View BVdb publication page



Treatment of advanced lung cancer based on genomic profiling using liquid biopsy (plasma): A review of three cases.

Thoracic Cancer
Mitsumura, Takahiro T; Kumaki, Yuichi Y; Takahashi, Kenta K; Matsudera, Shotaro S; Sakakibara, Rie R; Honda, Takayuki T; Ishizuka, Masahiro M; Iijima, Yuki Y; Shirai, Tsuyoshi T; Okamoto, Tsukasa T; Tateishi, Tomoya T; Sakashita, Hiroyuki H; Miyake, Satoshi S; Ikeda, Sadakatsu S; Miyazaki, Yasunari Y
Publication Date: 2021-09

Variant appearance in text: ALK: F1174C
PubMed Link: 34378333
Variant Present in the following documents:
  • Main text
View BVdb publication page



Treatment of advanced lung cancer based on genomic profiling using liquid biopsy (plasma): A review of three cases.

Thoracic Cancer
Mitsumura, Takahiro T; Kumaki, Yuichi Y; Takahashi, Kenta K; Matsudera, Shotaro S; Sakakibara, Rie R; Honda, Takayuki T; Ishizuka, Masahiro M; Iijima, Yuki Y; Shirai, Tsuyoshi T; Okamoto, Tsukasa T; Tateishi, Tomoya T; Sakashita, Hiroyuki H; Miyake, Satoshi S; Ikeda, Sadakatsu S; Miyazaki, Yasunari Y
Publication Date: 2021-09

Variant appearance in text: ALK: F1174C
PubMed Link: 34378333
Variant Present in the following documents:
  • Main text
View BVdb publication page



Will the clinical development of 4th-generation "double mutant active" ALK TKIs (TPX-0131 and NVL-655) change the future treatment paradigm of ALK+ NSCLC?

Translational Oncology
Ou, Sai-Hong Ignatius SI; Nagasaka, Misako M; Brazel, Danielle D; Hou, Yujie Y; Zhu, Viola W VW
Publication Date: 2021-11

Variant appearance in text: ALK: F1174C
PubMed Link: 34365220
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Update on molecular pathology and role of liquid biopsy in nonsmall cell lung cancer.

European Respiratory Review : An Official Journal Of The European Respiratory Society
Abdayem, Pamela P; Planchard, David D
Publication Date: 2021-09-30

Variant appearance in text: ALK: F1174C
PubMed Link: 34289984
Variant Present in the following documents:
  • Main text
  • ERR-0294-2020.pdf
View BVdb publication page



Circulating tumor cell copy-number heterogeneity in ALK-rearranged non-small-cell lung cancer resistant to ALK inhibitors.

Npj Precision Oncology
Oulhen, Marianne M; Pawlikowska, Patrycja P; Tayoun, Tala T; Garonzi, Marianna M; Buson, Genny G; Forcato, Claudio C; Manaresi, Nicolò N; Aberlenc, Agathe A; Mezquita, Laura L; Lecluse, Yann Y; Lavaud, Pernelle P; Naltet, Charles C; Planchard, David D; Besse, Benjamin B; Farace, Françoise F
Publication Date: 2021-07-16

Variant appearance in text: ALK: F1174C
PubMed Link: 34272470
Variant Present in the following documents:
  • 41698_2021_Article_203.pdf
View BVdb publication page