ALK c.1457T>C ;(p.F486S)

Variant ID: 2-29543706-A-G

NM_004304.4(ALK):c.1457T>C;(p.F486S)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Past, present, and future of Bcr-Abl inhibitors: from chemical development to clinical efficacy.

Journal Of Hematology & Oncology
Rossari, Federico F; Minutolo, Filippo F; Orciuolo, Enrico E
Publication Date: 2018-06-20

Variant appearance in text: ALK: F486S
PubMed Link: 29925402
Variant Present in the following documents:
  • Main text
  • 13045_2018_Article_624.pdf
View BVdb publication page



Second-Generation Tyrosine Kinase Inhibitors (Tki) as Salvage Therapy for Resistant or Intolerant Patients to Prior TKIs.

Mediterranean Journal Of Hematology And Infectious Diseases
Breccia, Massimo M; Alimena, Giuliana G
Publication Date: 2014-01-02

Variant appearance in text: ALK: F486S
PubMed Link: 24455112
Variant Present in the following documents:
  • Main text
  • mjhid-6-1-e2014003.pdf
View BVdb publication page



Chaperones as thermodynamic sensors of drug-target interactions reveal kinase inhibitor specificities in living cells.

Nature Biotechnology
Taipale, Mikko M; Krykbaeva, Irina I; Whitesell, Luke L; Santagata, Sandro S; Zhang, Jianming J; Liu, Qingsong Q; Gray, Nathanael S NS; Lindquist, Susan S
Publication Date: 2013-07

Variant appearance in text: ALK: F486S
PubMed Link: 23811600
Variant Present in the following documents:
  • NIHMS484224-supplement-2.xlsx, sheet 2
View BVdb publication page