ITPA c.124+21A>C

Variant ID: 20-3193893-A-C

NM_033453.3(ITPA):c.124+21A>C

This variant was identified in 90 publications

View GRCh38 version.




Publications:


Genetic variants of genes involved in thiopurine metabolism pathway are associated with 6-mercaptopurine toxicity in pediatric acute lymphoblastic leukemia patients from Ethiopia.

Frontiers In Pharmacology
Ali, Awol Mekonnen AM; Adam, Haileyesus H; Hailu, Daniel D; Engidawork, Ephrem E; Howe, Rawleigh R; Abula, Teferra T; Coenen, Marieke J H MJH
Publication Date: 2023

Variant appearance in text: rs7270101
PubMed Link: 37251339
Variant Present in the following documents:
  • Main text
  • fphar-14-1159307.pdf
View BVdb publication page



Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23

Variant appearance in text: ITPA: 124+21A>C
PubMed Link: 36823319
Variant Present in the following documents:
  • 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6
View BVdb publication page



Establishment and characterization of a new mantle cell lymphoma cell line with a NOTCH2 mutation, Arbo.

Ejhaem
Safa, Firas F; Rasmussen, Terri T; Lobelle-Rich, Patricia P; Collier, Stephanie S; Milligan, Nicholas N; Schmeig, John J; Schmid, Janet J; Wiewiorowski, Carol C; Totaro, Denise D; Brown, Theresa C TC; Satyavarapu, Ishwarya I; Badoo, Melody M; Ungerleider, Nathan N; Flemington, Erik K EK; Safah, Hana H; Saba, Nakhle S NS
Publication Date: 2022-11

Variant appearance in text: rs7270101
PubMed Link: 36467812
Variant Present in the following documents:
  • JHA2-3-1326-s001.xlsx, sheet 1
View BVdb publication page



Pharmacogenes that demonstrate high association evidence according to CPIC, DPWG, and PharmGKB.

Frontiers In Medicine
Alshabeeb, Mohammad A MA; Alyabsi, Mesnad M; Aziz, Mohammad A MA; Abohelaika, Salah S
Publication Date: 2022

Variant appearance in text: rs7270101
PubMed Link: 36388934
Variant Present in the following documents:
  • Main text
  • fmed-09-1001876.pdf
View BVdb publication page



Personalized medicine to implementation science: Thiopurines set for the leap.

Jgh Open : An Open Access Journal Of Gastroenterology And Hepatology
Sharma, Vishal V; Kedia, Saurabh S; Ahuja, Vineet V
Publication Date: 2022-10

Variant appearance in text: rs7270101
PubMed Link: 36262539
Variant Present in the following documents:
  • Main text
  • JGH3-6-651.pdf
View BVdb publication page



Optimizing thiopurine therapy in children with acute lymphoblastic leukemia: A promising "MINT" sequencing strategy and therapeutic "DNA-TG" monitoring.

Frontiers In Pharmacology
Guo, Hong-Li HL; Zhao, Yue-Tao YT; Wang, Wei-Jun WJ; Dong, Na N; Hu, Ya-Hui YH; Zhang, Yuan-Yuan YY; Chen, Feng F; Zhou, Li L; Li, Tao T
Publication Date: 2022

Variant appearance in text: rs7270101
PubMed Link: 36238550
Variant Present in the following documents:
  • Main text
  • fphar-13-941182.pdf
View BVdb publication page



Precision Medicine: Determination of Ribavirin Urinary Metabolites in Relation to Drug Adverse Effects in HCV Patients.

International Journal Of Molecular Sciences
Giampaoli, Ottavia O; Sciubba, Fabio F; Biliotti, Elisa E; Spagnoli, Mariangela M; Calvani, Riccardo R; Tomassini, Alberta A; Capuani, Giorgio G; Miccheli, Alfredo A; Taliani, Gloria G
Publication Date: 2022-09-02

Variant appearance in text: rs7270101
PubMed Link: 36077436
Variant Present in the following documents:
  • Main text
  • ijms-23-10043.pdf
View BVdb publication page



Pharmacogenetics implementation in the clinics: information and guidelines for germline variants.

Cancer Drug Resistance (Alhambra, Calif.)
Olivera, Gladys G; Sendra, Luis L; Herrero, María José MJ; Berlanga, Pablo P; Gargallo, Pablo P; Yáñez, Yania Y; Urtasun, Andrea A; de Mora, Jaime Font JF; Castel, Victoria V; Cañete, Adela A; Aliño, Salvador F SF
Publication Date: 2019

Variant appearance in text: rs7270101
PubMed Link: 35582138
Variant Present in the following documents:
  • cdr-2-53.pdf
View BVdb publication page



Pharmacogenetics of Dolutegravir Plasma Exposure Among Southern Africans With Human Immunodeficiency Virus.

The Journal Of Infectious Diseases
Cindi, Zinhle Z; Kawuma, Aida N AN; Maartens, Gary G; Bradford, Yuki Y; Venter, Francois F; Sokhela, Simiso S; Chandiwana, Nomathemba N; Wasmann, Roeland E RE; Denti, Paolo P; Wiesner, Lubbe L; Ritchie, Marylyn D MD; Haas, David W DW; Sinxadi, Phumla P
Publication Date: 2022-11-01

Variant appearance in text: rs7270101
PubMed Link: 35512135
Variant Present in the following documents:
  • EMS145648-supplement-Supplementary_file.pdf
View BVdb publication page



Pharmacogenetics and Precision Medicine Approaches for the Improvement of COVID-19 Therapies.

Frontiers In Pharmacology
Biswas, Mohitosh M; Sawajan, Nares N; Rungrotmongkol, Thanyada T; Sanachai, Kamonpan K; Ershadian, Maliheh M; Sukasem, Chonlaphat C
Publication Date: 2022

Variant appearance in text: rs7270101
PubMed Link: 35250581
Variant Present in the following documents:
  • Main text
  • fphar-13-835136.pdf
View BVdb publication page



Inosine Triphosphate Pyrophosphatase (ITPase): Functions, Mutations, Polymorphisms and Its Impact on Cancer Therapies.

Cells
Zamzami, Mazin A MA
Publication Date: 2022-01-24

Variant appearance in text: rs7270101
PubMed Link: 35159194
Variant Present in the following documents:
  • Main text
  • cells-11-00384.pdf
View BVdb publication page



Inosine Triphosphate Pyrophosphatase (ITPase): Functions, Mutations, Polymorphisms and Its Impact on Cancer Therapies.

Cells
Zamzami, Mazin A MA
Publication Date: 2022-01-24

Variant appearance in text: rs7270101
PubMed Link: 35159194
Variant Present in the following documents:
  • Main text
  • cells-11-00384.pdf
View BVdb publication page



Genophenotypic Factors and Pharmacogenomics in Adverse Drug Reactions.

International Journal Of Molecular Sciences
Cacabelos, Ramón R; Naidoo, Vinogran V; Corzo, Lola L; Cacabelos, Natalia N; Carril, Juan C JC
Publication Date: 2021-12-10

Variant appearance in text: rs7270101
PubMed Link: 34948113
Variant Present in the following documents:
  • Main text
  • ijms-22-13302.pdf
View BVdb publication page



Genophenotypic Factors and Pharmacogenomics in Adverse Drug Reactions.

International Journal Of Molecular Sciences
Cacabelos, Ramón R; Naidoo, Vinogran V; Corzo, Lola L; Cacabelos, Natalia N; Carril, Juan C JC
Publication Date: 2021-12-10

Variant appearance in text: rs7270101
PubMed Link: 34948113
Variant Present in the following documents:
  • Main text
  • ijms-22-13302.pdf
View BVdb publication page



Pharmacogenomic landscape of COVID-19 therapies from Indian population genomes.

Pharmacogenomics
Sahana, S S; Sivadas, Ambily A; Mangla, Mohit M; Jain, Abhinav A; Bhoyar, Rahul C RC; Pandhare, Kavita K; Mishra, Anushree A; Sharma, Disha D; Imran, Mohamed M; Senthivel, Vigneshwar V; Divakar, Mohit Kumar MK; Rophina, Mercy M; Jolly, Bani B; Batra, Arushi A; Sharma, Sumit S; Siwach, Sanjay S; Jadhao, Arun G AG; Palande, Nikhil V NV; Jha, Ganga Nath GN; Ashrafi, Nishat N; Mishra, Prashant Kumar PK; Vidhya, A K AK; Jain, Suman S; Dash, Debasis D; Kumar, Nachimuthu Senthil NS; Vanlallawma, Andrew A; Sarma, Ranjan Jyoti RJ; Chhakchhuak, Lalchhandama L; Kalyanaraman, Shantaraman S; Mahadevan, Radha R; Kandasamy, Sunitha S; Devi, Pabitha P; Rajagopal, Raskin Erusan RE; Ramya, J Ezhil JE; Devi, P Nirmala PN; Bajaj, Anjali A; Gupta, Vishu V; Mathew, Samatha S; Goswami, Sangam S; Prakash, Savinitha S; Joshi, Kandarp K; Kumla, Meya M; Sreedevi, S S; Gajjar, Devarshi D; Soraisham, Ronibala R; Yadav, Rohit R; Devi, Yumnam Silla YS; Gupta, Aayush A; Mukerji, Mitali M; Ramalingam, Sivaprakash S; Binukumar, B K BK; Sivasubbu, Sridhar S; Scaria, Vinod V
Publication Date: 2021-07

Variant appearance in text: rs7270101
PubMed Link: 34142560
Variant Present in the following documents:
  • Main text
  • pgs-2021-0028.pdf
View BVdb publication page



The Effect of NUDT15, TPMT, APEX1, and ITPA Genetic Variations on Mercaptopurine Treatment of Pediatric Acute Lymphoblastic Leukemia.

Children (Basel, Switzerland)
Lee, Jae Min JM; Shim, Ye Jee YJ; Kim, Do-Hoon DH; Jung, Nani N; Ha, Jung-Sook JS
Publication Date: 2021-03-15

Variant appearance in text: rs7270101
PubMed Link: 33804051
Variant Present in the following documents:
  • Main text
  • children-08-00224.pdf
View BVdb publication page



Pharmacogenomics of genetic polymorphism within the genes responsible for SARS-CoV-2 susceptibility and the drug-metabolising genes used in treatment.

Reviews In Medical Virology
Al-Eitan, Laith N LN; Alahmad, Saif Z SZ
Publication Date: 2021-07

Variant appearance in text: rs7270101
PubMed Link: 33205496
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacogenomics of genetic polymorphism within the genes responsible for SARS-CoV-2 susceptibility and the drug-metabolising genes used in treatment.

Reviews In Medical Virology
Al-Eitan, Laith N LN; Alahmad, Saif Z SZ
Publication Date: 2021-07

Variant appearance in text: rs7270101
PubMed Link: 33205496
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacogenomics and Pharmacogenetics: In Silico Prediction of Drug Effects in Treatments for Novel Coronavirus SARS-CoV2 Disease.

Pharmacogenomics And Personalized Medicine
Cafiero, Concetta C; Re, Agnese A; Micera, Alessandra A; Palmirotta, Raffaele R; Monaco, Delio D; Romano, Francesca F; Fabrizio, Claudia C; Di Francia, Raffaele R; Cacciamani, Andrea A; Surico, Pier Luigi PL; D'Amato, Gerardo G; Pisconti, Salvatore S
Publication Date: 2020

Variant appearance in text: ITPA: 124+21A>C; rs7270101
PubMed Link: 33116761
Variant Present in the following documents:
  • Main text
  • pgpm-13-463.pdf
View BVdb publication page



Comprehensive Custom NGS Panel Validation for the Improvement of the Stratification of B-Acute Lymphoblastic Leukemia Patients.

Journal Of Personalized Medicine
Montaño, Adrián A; Hernández-Sánchez, Jesús J; Forero-Castro, Maribel M; Matorra-Miguel, María M; Lumbreras, Eva E; Miguel, Cristina C; Santos, Sandra S; Ramírez-Maldonado, Valentina V; Fuster, José Luís JL; de Las Heras, Natalia N; García-de Coca, Alfonso A; Sierra, Magdalena M; Dávila, Julio J; de la Fuente, Ignacio I; Olivier, Carmen C; Olazabal, Juan J; Martínez, Joaquín J; Vega-García, Nerea N; González, Teresa T; Hernández-Rivas, Jesús María JM; Benito, Rocío R
Publication Date: 2020-09-21

Variant appearance in text: rs7270101
PubMed Link: 32967112
Variant Present in the following documents:
  • jpm-10-00137-s001.pdf
View BVdb publication page



Pharmacogenomics of COVID-19 therapies.

Npj Genomic Medicine
Takahashi, Takuto T; Luzum, Jasmine A JA; Nicol, Melanie R MR; Jacobson, Pamala A PA
Publication Date: 2020

Variant appearance in text: rs7270101
PubMed Link: 32864162
Variant Present in the following documents:
  • Main text
View BVdb publication page



Implementation of Pharmacogenetics to Individualize Treatment Regimens for Children with Acute Lymphoblastic Leukemia.

Pharmacogenomics And Personalized Medicine
Maamari, Dimitri D; El-Khoury, Habib H; Saifi, Omran O; Muwakkit, Samar A SA; Zgheib, Nathalie K NK
Publication Date: 2020

Variant appearance in text: rs7270101
PubMed Link: 32848445
Variant Present in the following documents:
  • Main text
View BVdb publication page



Tests that now deserve to be more widely adopted in IBD clinical practice.

Therapeutic Advances In Gastroenterology
Labarile, Nunzia N; Ghosh, Subrata S; Ng, Siew C SC; Walters, Julian J; Iacucci, Marietta M
Publication Date: 2020

Variant appearance in text: rs7270101
PubMed Link: 32782481
Variant Present in the following documents:
  • Main text
  • 10.1177_1756284820944088.pdf
View BVdb publication page



Unique insights from ClinicalTrials.gov by mining protein mutations and RSids in addition to applying the Human Phenotype Ontology.

Plos One
Alag, Shray S
Publication Date: 2020

Variant appearance in text: rs7270101
PubMed Link: 32459809
Variant Present in the following documents:
  • Main text
  • pone.0233438.pdf
View BVdb publication page



ITPA, TPMT, and NUDT15 Genetic Polymorphisms Predict 6-Mercaptopurine Toxicity in Middle Eastern Children With Acute Lymphoblastic Leukemia.

Frontiers In Pharmacology
Moradveisi, Borhan B; Muwakkit, Samar S; Zamani, Fatemeh F; Ghaderi, Ebrahim E; Mohammadi, Ebrahim E; Zgheib, Nathalie K NK
Publication Date: 2019

Variant appearance in text: rs7270101
PubMed Link: 31507415
Variant Present in the following documents:
  • Main text
  • fphar-10-00916.pdf
View BVdb publication page



Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases.

Cell Death & Disease
Grassi, Ludovica L; Alfonsi, Romina R; Francescangeli, Federica F; Signore, Michele M; De Angelis, Maria Laura ML; Addario, Antonio A; Costantini, Manuela M; Flex, Elisabetta E; Ciolfi, Andrea A; Pizzi, Simone S; Bruselles, Alessandro A; Pallocca, Matteo M; Simone, Giuseppe G; Haoui, Mustapha M; Falchi, Mario M; Milella, Michele M; Sentinelli, Steno S; Di Matteo, Paola P; Stellacci, Emilia E; Gallucci, Michele M; Muto, Giovanni G; Tartaglia, Marco M; De Maria, Ruggero R; Bonci, Désirée D
Publication Date: 2019-02-27

Variant appearance in text: ITPA: 124+21A>C; rs7270101
PubMed Link: 30814510
Variant Present in the following documents:
  • 41419_2019_1453_MOESM27_ESM.xlsx, sheet 3
View BVdb publication page



Whole genome sequencing identifies high-impact variants in well-known pharmacogenomic genes.

The Pharmacogenomics Journal
Choi, Jihoon J; Tantisira, Kelan G KG; Duan, Qing Ling QL
Publication Date: 2019-04

Variant appearance in text: rs7270101
PubMed Link: 30214008
Variant Present in the following documents:
  • NIHMS1503453-supplement-3.xlsx, sheet 1
View BVdb publication page



Inosine Triphosphate Pyrophosphatase Dephosphorylates Ribavirin Triphosphate and Reduced Enzymatic Activity Potentiates Mutagenesis in Hepatitis C Virus.

Journal Of Virology
Nyström, Kristina K; Wanrooij, Paulina H PH; Waldenström, Jesper J; Adamek, Ludmila L; Brunet, Sofia S; Said, Joanna J; Nilsson, Staffan S; Wind-Rotolo, Megan M; Hellstrand, Kristoffer K; Norder, Helene H; Tang, Ka-Wei KW; Lagging, Martin M
Publication Date: 2018-10-01

Variant appearance in text: rs7270101
PubMed Link: 30045981
Variant Present in the following documents:
  • Main text
  • e01087-18.pdf
View BVdb publication page



Reduced ITPase activity and favorable IL28B genetic variant protect against ribavirin-induced anemia in interferon-free regimens.

Plos One
Vasanthakumar, Aparna A; Davis, Justin W JW; Abunimeh, Manal M; Söderholm, Jonas J; Zha, Jiuhong J; Dumas, Emily O EO; Cohen, Daniel E DE; Waring, Jeffrey F JF; Lagging, Martin M
Publication Date: 2018

Variant appearance in text: rs7270101
PubMed Link: 29851985
Variant Present in the following documents:
  • Main text
View BVdb publication page



Optimal predictor for 6-mercaptopurine intolerance in Chinese children with acute lymphoblastic leukemia: NUDT15, TPMT, or ITPA genetic variants?

Bmc Cancer
Zhou, Hong H; Li, Lei L; Yang, Peng P; Yang, Lin L; Zheng, Jin E JE; Zhou, Ying Y; Han, Yong Y
Publication Date: 2018-05-02

Variant appearance in text: rs7270101
PubMed Link: 29720126
Variant Present in the following documents:
  • Main text
  • 12885_2018_Article_4398.pdf
View BVdb publication page



A facile PCR-RFLP method for genotyping of ITPA rs1127354 and rs7270101 polymorphisms.

Journal Of Clinical Laboratory Analysis
Alavian, Seyed Ehsan SE; Sharafi, Heidar H; Shirmast, Paniz P; Alavian, Seyed Moayed SM; Behnava, Bita B; Pouryasin, Mohammad M; Keshvari, Maryam M; Pouryasin, Ali A
Publication Date: 2018-09

Variant appearance in text: rs7270101
PubMed Link: 29660762
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of the independent polymorphisms in CDKN2A with susceptibility of acute lymphoblastic leukemia.

Bioscience Reports
Zhou, Xueyan X; Liao, Fei F; Zhang, Junlong J; Qin, Yun Y; Xu, Heng H; Ding, Zhenyu Z; Zhang, Yan Y; Zhang, Feng F
Publication Date: 2018-06-29

Variant appearance in text: rs7270101
PubMed Link: 29654170
Variant Present in the following documents:
  • Main text
  • bsr-38-bsr20180331.pdf
View BVdb publication page



Safety of Sofosbuvir and Ribavirin Combination Therapy in a Patient Who Developed Anemia due to Ribavirin.

Case Reports In Hepatology
Suii, Hirokazu H; Ozeki, Itaru I; Tatsumi, Ryoji R; Yamaguchi, Masakatsu M; Kimura, Mutsuumi M; Arakawa, Tomohiro T; Nakajima, Tomoaki T; Kuwata, Yasuaki Y; Ohmura, Takumi T; Hige, Shuhei S; Karino, Yoshiyasu Y; Toyota, Joji J
Publication Date: 2017

Variant appearance in text: rs7270101
PubMed Link: 29375917
Variant Present in the following documents:
  • Main text
  • CRIHEP2017-8793895.pdf
View BVdb publication page



Erythrocyte Inosine triphosphatase activity: A potential biomarker for adverse events during combination antiretroviral therapy for HIV.

Plos One
Peltenburg, N Chantal NC; Bierau, Jörgen J; Bakker, Jaap A JA; Schippers, Jolanda A JA; Lowe, Selwyn H SH; Paulussen, Aimée D C ADC; van den Bosch, Bianca J C BJC; Leers, Mathie P G MPG; Hansen, Bettina E BE; Verbon, Annelies A
Publication Date: 2018

Variant appearance in text: ITPA: 124+21A>C; rs7270101
PubMed Link: 29329318
Variant Present in the following documents:
  • Main text
View BVdb publication page



The rs1127354 Polymorphism in ITPA Is Associated with Susceptibility to Infertility.

Cell Journal
Mollaahmadi, Fahimeh F; Moini, Ashraf A; Salman Yazdi, Reza R; Behmanesh, Mehrdad M
Publication Date: 2018-04

Variant appearance in text: rs7270101
PubMed Link: 29308621
Variant Present in the following documents:
  • Main text
  • Cell-J-20-73.pdf
View BVdb publication page



APEX1 Polymorphism and Mercaptopurine-Related Early Onset Neutropenia in Pediatric Acute Lymphoblastic Leukemia.

Cancer Research And Treatment
Kim, Hyery H; Seo, Heewon H; Park, Yoomi Y; Min, Byung-Joo BJ; Seo, Myung-Eui ME; Park, Kyung Duk KD; Shin, Hee Young HY; Kim, Ju Han JH; Kang, Hyoung Jin HJ
Publication Date: 2018-07

Variant appearance in text: rs7270101
PubMed Link: 28882023
Variant Present in the following documents:
  • Main text
  • crt-2017-351.pdf
View BVdb publication page



Real world experience with pegylated interferon and ribavirin in hepatitis C genotype 1 population with favourable IL28B polymorphism.

Gastroenterology Report
Ekstrom, Victoria V; Kumar, Rajneesh R; Zhao, Yi Y; Yee, Mei Ling ML; Sung, Cynthia C; Toh, Dorothy D; Loh, Poh Yen PY; Tan, Jessica J; Teo, Eng Kiong EK; Chow, Wan Cheng WC
Publication Date: 2017-08

Variant appearance in text: rs7270101
PubMed Link: 28852525
Variant Present in the following documents:
  • Main text
View BVdb publication page



The relationship between ITPA rs1127354 polymorphisms and efficacy of antiviral treatment in Northeast Chinese CHC patients.

Medicine
Liu, Zhenhua Z; Wang, Song S; Qi, Wenqian W; Wang, Xu X; Sun, Derong D; Wang, Hongguang H; Zhang, Yonggui Y; Li, Zhongxie Z; Zhu, Liying L; Zhao, Ping P; Guo, Honghua H; Zhou, Changyu C; Wang, Jiangbin J
Publication Date: 2017-07

Variant appearance in text: rs7270101
PubMed Link: 28723780
Variant Present in the following documents:
  • Main text
  • medi-96-e7554.pdf
View BVdb publication page



Sources of discordance among germ-line variant classifications in ClinVar.

Genetics In Medicine : Official Journal Of The American College Of Medical Genetics
Yang, Shan S; Lincoln, Stephen E SE; Kobayashi, Yuya Y; Nykamp, Keith K; Nussbaum, Robert L RL; Topper, Scott S
Publication Date: 2017-10

Variant appearance in text: ITPA: 124+21A>C
PubMed Link: 28569743
Variant Present in the following documents:
  • gim201760x7.xlsx, sheet 2
View BVdb publication page



Hepatitis C virus pharmacogenomics in Latin American populations: implications in the era of direct-acting antivirals.

Pharmacogenomics And Personalized Medicine
Trinks, Julieta J; Caputo, Mariela M; Hulaniuk, María L ML; Corach, Daniel D; Flichman, Diego D
Publication Date: 2017

Variant appearance in text: rs7270101
PubMed Link: 28405170
Variant Present in the following documents:
  • Main text
View BVdb publication page



Polymorphisms and Pharmacogenomics for the Clinical Efficacy of Methotrexate in Patients with Rheumatoid Arthritis: A Systematic Review and Meta-analysis.

Scientific Reports
Qiu, Qi Q; Huang, Jing J; Shu, Xiaoming X; Fan, Huizheng H; Zhou, Youwen Y; Xiao, Cheng C
Publication Date: 2017-03-07

Variant appearance in text: rs7270101
PubMed Link: 28266606
Variant Present in the following documents:
  • Main text
  • srep44015.pdf
View BVdb publication page



IL28B genotype is associated with cirrhosis or transition to cirrhosis in treatment-naive patients with chronic HCV genotype 1 infection: the international observational Gen-C study.

Springerplus
Mangia, Alessandra A; De Ledinghen, Victor V; Bailly, François F; Brahm, Javier J; Keiss, Jazeps J; Valantinas, Jonas J; Rasmann, Nele N; Messinger, Diethelm D; Tatsch, Fernando F; Bakalos, Georgios G; Foster, Graham R GR; ,
Publication Date: 2016

Variant appearance in text: rs7270101
PubMed Link: 27917361
Variant Present in the following documents:
  • Main text
View BVdb publication page



A disease spectrum for ITPA variation: advances in biochemical and clinical research.

Journal Of Biomedical Science
Burgis, Nicholas E NE
Publication Date: 2016-10-22

Variant appearance in text: rs7270101
PubMed Link: 27770805
Variant Present in the following documents:
  • Main text
  • 12929_2016_Article_291.pdf
View BVdb publication page



PACSIN2 polymorphism is associated with thiopurine-induced hematological toxicity in children with acute lymphoblastic leukaemia undergoing maintenance therapy.

Scientific Reports
Smid, Alenka A; Karas-Kuzelicki, Natasa N; Jazbec, Janez J; Mlinaric-Rascan, Irena I
Publication Date: 2016-07-25

Variant appearance in text: rs7270101
PubMed Link: 27452984
Variant Present in the following documents:
  • Main text
View BVdb publication page



A Simple Method for TPMT and ITPA Genotyping Using Multiplex HRMA for Patients Treated with Thiopurine Drugs.

Molecular Diagnosis & Therapy
Skrzypczak-Zielinska, Marzena M; Borun, Pawel P; Bartkowiak-Kaczmarek, Anna A; Zakerska-Banaszak, Oliwia O; Walczak, Michal M; Dobrowolska, Agnieszka A; Kurzawski, Mateusz M; Waszak, Malgorzata M; Lipinski, Daniel D; Plawski, Andrzej A; Slomski, Ryszard R
Publication Date: 2016-10

Variant appearance in text: rs7270101
PubMed Link: 27307154
Variant Present in the following documents:
  • Main text
  • 40291_2016_Article_217.pdf
View BVdb publication page



The ITPA and C20orf194 Polymorphisms and Hematological Changes During Treatment With Pegylated-Interferon Plus Ribavirin in Patients With Chronic Hepatitis C.

Hepatitis Monthly
Pouryasin, Mohammad M; Keshvari, Maryam M; Sharafi, Heidar H; Alavian, Seyed Moayed SM; Behnava, Bita B; Alavian, Seyed Ehsan SE; Pouryasin, Ali A
Publication Date: 2016-02

Variant appearance in text: rs7270101
PubMed Link: 27148387
Variant Present in the following documents:
  • Main text
View BVdb publication page



Modeling Ribavirin-Induced Anemia in Patients with Chronic Hepatitis C Virus.

Cpt: Pharmacometrics & Systems Pharmacology
Wu, L S LS; Jimmerson, L C LC; MacBrayne, C E CE; Kiser, J J JJ; D'Argenio, D Z DZ
Publication Date: 2016-02

Variant appearance in text: rs7270101
PubMed Link: 26933517
Variant Present in the following documents:
  • Main text
View BVdb publication page



Recent advances in management of the HIV/HCV coinfected patient.

Future Virology
Bednasz, Cindy J CJ; Sawyer, Joshua R JR; Martinez, Anthony A; Rose, Patrick G PG; Sithole, Samantha S SS; Hamilton, Holly R HR; Kaufman, Farzia S FS; Venuto, Charles S CS; Ma, Qing Q; Talal, Andrew A; Morse, Gene D GD
Publication Date: 2015

Variant appearance in text: rs7270101
PubMed Link: 26877758
Variant Present in the following documents:
  • Main text
View BVdb publication page



Impact of IL28B, APOH and ITPA Polymorphisms on Efficacy and Safety of TVR- or BOC-Based Triple Therapy in Treatment-Experienced HCV-1 Patients with Compensated Cirrhosis from the ANRS CO20-CUPIC Study.

Plos One
About, Frédégonde F; Oudot-Mellakh, Tiphaine T; Niay, Jonathan J; Rabiéga, Pascaline P; Pedergnana, Vincent V; Duffy, Darragh D; Sultanik, Philippe P; Cagnot, Carole C; Carrat, Fabrice F; Marcellin, Patrick P; Zoulim, Fabien F; Larrey, Dominique D; Hézode, Christophe C; Fontaine, Hélène H; Bronowicki, Jean-Pierre JP; Pol, Stanislas S; Albert, Matthew L ML; Theodorou, Ioannis I; Cobat, Aurélie A; Abel, Laurent L; ,
Publication Date: 2015

Variant appearance in text: rs7270101
PubMed Link: 26670100
Variant Present in the following documents:
  • Main text
  • pone.0145105.pdf
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