Height-Related Polygenic Variants Are Associated with Metabolic Syndrome Risk and Interact with Energy Intake and a Rice-Main Diet to Influence Height in KoGES.
Genome-Wide Association Study and Transcriptome of Japanese Patients with Developmental Dysplasia of the Hip Demonstrates an Association with the Ferroptosis Signaling Pathway.
Gene polymorphisms associated with heterogeneity and senescence characteristics of sarcopenia in chronic obstructive pulmonary disease.
Journal Of Cachexia, Sarcopenia And Muscle
Attaway, Amy H AH; Bellar, Annette A; Welch, Nicole N; Sekar, Jinendiran J; Kumar, Avinash A; Mishra, Saurabh S; Hatipoğlu, Umur U; McDonald, Merry-Lynn ML; Regan, Elizabeth A EA; Smith, Jonathan D JD; Washko, George G; Estépar, Raúl San José RSJ; Bazeley, Peter P; Zein, Joe J; Dasarathy, Srinivasan S
A genome-wide association study identifies distinct variants associated with pulmonary function among European and African ancestries from the UK Biobank.
Communications Biology
Sinkala, Musalula M; Elsheikh, Samar S M SSM; Mbiyavanga, Mamana M; Cullinan, Joshua J; Mulder, Nicola J NJ
Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
The Link between Type 2 Diabetes Mellitus and the Polymorphisms of Glutathione-Metabolizing Genes Suggests a New Hypothesis Explaining Disease Initiation and Progression.
Life (Basel, Switzerland)
Azarova, Iuliia I; Klyosova, Elena E; Polonikov, Alexey A
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.
Cell
Boer, Cindy G CG; Hatzikotoulas, Konstantinos K; Southam, Lorraine L; Stefánsdóttir, Lilja L; Zhang, Yanfei Y; Coutinho de Almeida, Rodrigo R; Wu, Tian T TT; Zheng, Jie J; Hartley, April A; Teder-Laving, Maris M; Skogholt, Anne Heidi AH; Terao, Chikashi C; Zengini, Eleni E; Alexiadis, George G; Barysenka, Andrei A; Bjornsdottir, Gyda G; Gabrielsen, Maiken E ME; Gilly, Arthur A; Ingvarsson, Thorvaldur T; Johnsen, Marianne B MB; Jonsson, Helgi H; Kloppenburg, Margreet M; Luetge, Almut A; Lund, Sigrun H SH; Mägi, Reedik R; Mangino, Massimo M; Nelissen, Rob R G H H RRGHH; Shivakumar, Manu M; Steinberg, Julia J; Takuwa, Hiroshi H; Thomas, Laurent F LF; Tuerlings, Margo M; , ; , ; , ; , ; Babis, George C GC; Cheung, Jason Pui Yin JPY; Kang, Jae Hee JH; Kraft, Peter P; Lietman, Steven A SA; Samartzis, Dino D; Slagboom, P Eline PE; Stefansson, Kari K; Thorsteinsdottir, Unnur U; Tobias, Jonathan H JH; Uitterlinden, André G AG; Winsvold, Bendik B; Zwart, John-Anker JA; Davey Smith, George G; Sham, Pak Chung PC; Thorleifsson, Gudmar G; Gaunt, Tom R TR; Morris, Andrew P AP; Valdes, Ana M AM; Tsezou, Aspasia A; Cheah, Kathryn S E KSE; Ikegawa, Shiro S; Hveem, Kristian K; Esko, Tõnu T; Wilkinson, J Mark JM; Meulenbelt, Ingrid I; Lee, Ming Ta Michael MTM; van Meurs, Joyce B J JBJ; Styrkársdóttir, Unnur U; Zeggini, Eleftheria E
Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry.
American Journal Of Human Genetics
Graff, Mariaelisa M; Justice, Anne E AE; Young, Kristin L KL; Marouli, Eirini E; Zhang, Xinruo X; Fine, Rebecca S RS; Lim, Elise E; Buchanan, Victoria V; Rand, Kristin K; Feitosa, Mary F MF; Wojczynski, Mary K MK; Yanek, Lisa R LR; Shao, Yaming Y; Rohde, Rebecca R; Adeyemo, Adebowale A AA; Aldrich, Melinda C MC; Allison, Matthew A MA; Ambrosone, Christine B CB; Ambs, Stefan S; Amos, Christopher C; Arnett, Donna K DK; Atwood, Larry L; Bandera, Elisa V EV; Bartz, Traci T; Becker, Diane M DM; Berndt, Sonja I SI; Bernstein, Leslie L; Bielak, Lawrence F LF; Blot, William J WJ; Bottinger, Erwin P EP; Bowden, Donald W DW; Bradfield, Jonathan P JP; Brody, Jennifer A JA; Broeckel, Ulrich U; Burke, Gregory G; Cade, Brian E BE; Cai, Qiuyin Q; Caporaso, Neil N; Carlson, Chris C; Carpten, John J; Casey, Graham G; Chanock, Stephen J SJ; Chen, Guanjie G; Chen, Minhui M; Chen, Yii-Der I YI; Chen, Wei-Min WM; Chesi, Alessandra A; Chiang, Charleston W K CWK; Chu, Lisa L; Coetzee, Gerry A GA; Conti, David V DV; Cooper, Richard S RS; Cushman, Mary M; Demerath, Ellen E; Deming, Sandra L SL; Dimitrov, Latchezar L; Ding, Jingzhong J; Diver, W Ryan WR; Duan, Qing Q; Evans, Michele K MK; Falusi, Adeyinka G AG; Faul, Jessica D JD; Fornage, Myriam M; Fox, Caroline C; Freedman, Barry I BI; Garcia, Melissa M; Gillanders, Elizabeth M EM; Goodman, Phyllis P; Gottesman, Omri O; Grant, Struan F A SFA; Guo, Xiuqing X; Hakonarson, Hakon H; Haritunians, Talin T; Harris, Tamara B TB; Harris, Curtis C CC; Henderson, Brian E BE; Hennis, Anselm A; Hernandez, Dena G DG; Hirschhorn, Joel N JN; McNeill, Lorna Haughton LH; Howard, Timothy D TD; Howard, Barbara B; Hsing, Ann W AW; Hsu, Yu-Han H YH; Hu, Jennifer J JJ; Huff, Chad D CD; Huo, Dezheng D; Ingles, Sue A SA; Irvin, Marguerite R MR; John, Esther M EM; Johnson, Karen C KC; Jordan, Joanne M JM; Kabagambe, Edmond K EK; Kang, Sun J SJ; Kardia, Sharon L SL; Keating, Brendan J BJ; Kittles, Rick A RA; Klein, Eric A EA; Kolb, Suzanne S; Kolonel, Laurence N LN; Kooperberg, Charles C; Kuller, Lewis L; Kutlar, Abdullah A; Lange, Leslie L; Langefeld, Carl D CD; Le Marchand, Loic L; Leonard, Hampton H; Lettre, Guillaume G; Levin, Albert M AM; Li, Yun Y; Li, Jin J; Liu, Yongmei Y; Liu, Youfang Y; Liu, Simin S; Lohman, Kurt K; Lotay, Vaneet V; Lu, Yingchang Y; Maixner, William W; Manson, JoAnn E JE; McKnight, Barbara B; Meng, Yan Y; Monda, Keri L KL; Monroe, Kris K; Moore, Jason H JH; Mosley, Thomas H TH; Mudgal, Poorva P; Murphy, Adam B AB; Nadukuru, Rajiv R; Nalls, Mike A MA; Nathanson, Katherine L KL; Nayak, Uma U; N'Diaye, Amidou A; Nemesure, Barbara B; Neslund-Dudas, Christine C; Neuhouser, Marian L ML; Nyante, Sarah S; Ochs-Balcom, Heather H; Ogundiran, Temidayo O TO; Ogunniyi, Adesola A; Ojengbede, Oladosu O; Okut, Hayrettin H; Olopade, Olufunmilayo I OI; Olshan, Andrew A; Padhukasahasram, Badri B; Palmer, Julie J; Palmer, Cameron D CD; Palmer, Nicholette D ND; Papanicolaou, George G; Patel, Sanjay R SR; Pettaway, Curtis A CA; Peyser, Patricia A PA; Press, Michael F MF; Rao, D C DC; Rasmussen-Torvik, Laura J LJ; Redline, Susan S; Reiner, Alex P AP; Rhie, Suhn K SK; Rodriguez-Gil, Jorge L JL; Rotimi, Charles N CN; Rotter, Jerome I JI; Ruiz-Narvaez, Edward A EA; Rybicki, Benjamin A BA; Salako, Babatunde B; Sale, Michele M MM; Sanderson, Maureen M; Schadt, Eric E; Schreiner, Pamela J PJ; Schurmann, Claudia C; Schwartz, Ann G AG; Shriner, Daniel A DA; Signorello, Lisa B LB; Singleton, Andrew B AB; Siscovick, David S DS; Smith, Jennifer A JA; Smith, Shad S; Speliotes, Elizabeth E; Spitz, Margaret M; Stanford, Janet L JL; Stevens, Victoria L VL; Stram, Alex A; Strom, Sara S SS; Sucheston, Lara L; Sun, Yan V YV; Tajuddin, Salman M SM; Taylor, Herman H; Taylor, Kira K; Tayo, Bamidele O BO; Thun, Michael J MJ; Tucker, Margaret A MA; Vaidya, Dhananjay D; Van Den Berg, David J DJ; Vedantam, Sailaja S; Vitolins, Mara M; Wang, Zhaoming Z; Ware, Erin B EB; Wassertheil-Smoller, Sylvia S; Weir, David R DR; Wiencke, John K JK; Williams, Scott M SM; Williams, L Keoki LK; Wilson, James G JG; Witte, John S JS; Wrensch, Margaret M; Wu, Xifeng X; Yao, Jie J; Zakai, Neil N; Zanetti, Krista K; Zemel, Babette S BS; Zhao, Wei W; Zhao, Jing Hua JH; Zheng, Wei W; Zhi, Degui D; Zhou, Jie J; Zhu, Xiaofeng X; Ziegler, Regina G RG; Zmuda, Joe J; Zonderman, Alan B AB; Psaty, Bruce M BM; Borecki, Ingrid B IB; Cupples, L Adrienne LA; Liu, Ching-Ti CT; Haiman, Christopher A CA; Loos, Ruth R; Ng, Maggie C Y MCY; North, Kari E KE
The limits of normal approximation for adult height.
European Journal Of Human Genetics : Ejhg
Slavskii, Sergei A SA; Kuznetsov, Ivan A IA; Shashkova, Tatiana I TI; Bazykin, Georgii A GA; Axenovich, Tatiana I TI; Kondrashov, Fyodor A FA; Aulchenko, Yurii S YS
Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women.
Nature Communications
Jones, Garan G; Trajanoska, Katerina K; Santanasto, Adam J AJ; Stringa, Najada N; Kuo, Chia-Ling CL; Atkins, Janice L JL; Lewis, Joshua R JR; Duong, ThuyVy T; Hong, Shengjun S; Biggs, Mary L ML; Luan, Jian'an J; Sarnowski, Chloe C; Lunetta, Kathryn L KL; Tanaka, Toshiko T; Wojczynski, Mary K MK; Cvejkus, Ryan R; Nethander, Maria M; Ghasemi, Sahar S; Yang, Jingyun J; Zillikens, M Carola MC; Walter, Stefan S; Sicinski, Kamil K; Kague, Erika E; Ackert-Bicknell, Cheryl L CL; Arking, Dan E DE; Windham, B Gwen BG; Boerwinkle, Eric E; Grove, Megan L ML; Graff, Misa M; Spira, Dominik D; Demuth, Ilja I; van der Velde, Nathalie N; de Groot, Lisette C P G M LCPGM; Psaty, Bruce M BM; Odden, Michelle C MC; Fohner, Alison E AE; Langenberg, Claudia C; Wareham, Nicholas J NJ; Bandinelli, Stefania S; van Schoor, Natasja M NM; Huisman, Martijn M; Tan, Qihua Q; Zmuda, Joseph J; Mellström, Dan D; Karlsson, Magnus M; Bennett, David A DA; Buchman, Aron S AS; De Jager, Philip L PL; Uitterlinden, Andre G AG; Völker, Uwe U; Kocher, Thomas T; Teumer, Alexander A; Rodriguéz-Mañas, Leocadio L; García, Francisco J FJ; Carnicero, José A JA; Herd, Pamela P; Bertram, Lars L; Ohlsson, Claes C; Murabito, Joanne M JM; Melzer, David D; Kuchel, George A GA; Ferrucci, Luigi L; Karasik, David D; Rivadeneira, Fernando F; Kiel, Douglas P DP; Pilling, Luke C LC
Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify WNT9A as novel osteoarthritis gene.
Annals Of The Rheumatic Diseases
Boer, Cindy Germaine CG; Yau, Michelle S MS; Rice, Sarah J SJ; Coutinho de Almeida, Rodrigo R; Cheung, Kathleen K; Styrkarsdottir, Unnur U; Southam, Lorraine L; Broer, Linda L; Wilkinson, Jeremy Mark JM; Uitterlinden, André G AG; Zeggini, Eleftheria E; Felson, David D; Loughlin, John J; Young, Mariel M; Capellini, Terence Dante TD; Meulenbelt, Ingrid I; van Meurs, Joyce Bj JB
Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify WNT9A as novel osteoarthritis gene.
Annals Of The Rheumatic Diseases
Boer, Cindy Germaine CG; Yau, Michelle S MS; Rice, Sarah J SJ; Coutinho de Almeida, Rodrigo R; Cheung, Kathleen K; Styrkarsdottir, Unnur U; Southam, Lorraine L; Broer, Linda L; Wilkinson, Jeremy Mark JM; Uitterlinden, André G AG; Zeggini, Eleftheria E; Felson, David D; Loughlin, John J; Young, Mariel M; Capellini, Terence Dante TD; Meulenbelt, Ingrid I; van Meurs, Joyce Bj JB
Analysis of genetically independent phenotypes identifies shared genetic factors associated with chronic musculoskeletal pain conditions.
Communications Biology
Tsepilov, Yakov A YA; Freidin, Maxim B MB; Shadrina, Alexandra S AS; Sharapov, Sodbo Z SZ; Elgaeva, Elizaveta E EE; Zundert, Jan van JV; Karssen, Lennart С LС; Suri, Pradeep P; Williams, Frances M K FMK; Aulchenko, Yurii S YS
Genetic Association Between Growth Differentiation Factor 5 Single Nucleotide Polymorphism and Primary Knee Osteoarthritis in a Group of Egyptian Patients: A Pilot Study.
Mediterranean Journal Of Rheumatology
Mohasseb, Dia Mohamed Fahmy DMF; Saba, Emmanuel Kamal Aziz EKA; Saad, Neveen Lewis Mikhael NLM; Sarofeem, Amira Dimas Hanna ADH
Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis.
American Journal Of Respiratory And Critical Care Medicine
Allen, Richard J RJ; Guillen-Guio, Beatriz B; Oldham, Justin M JM; Ma, Shwu-Fan SF; Dressen, Amy A; Paynton, Megan L ML; Kraven, Luke M LM; Obeidat, Ma'en M; Li, Xuan X; Ng, Michael M; Braybrooke, Rebecca R; Molina-Molina, Maria M; Hobbs, Brian D BD; Putman, Rachel K RK; Sakornsakolpat, Phuwanat P; Booth, Helen L HL; Fahy, William A WA; Hart, Simon P SP; Hill, Mike R MR; Hirani, Nik N; Hubbard, Richard B RB; McAnulty, Robin J RJ; Millar, Ann B AB; Navaratnam, Vidyia V; Oballa, Eunice E; Parfrey, Helen H; Saini, Gauri G; Whyte, Moira K B MKB; Zhang, Yingze Y; Kaminski, Naftali N; Adegunsoye, Ayodeji A; Strek, Mary E ME; Neighbors, Margaret M; Sheng, Xuting R XR; Gudmundsson, Gunnar G; Gudnason, Vilmundur V; Hatabu, Hiroto H; Lederer, David J DJ; Manichaikul, Ani A; Newell, John D JD; O'Connor, George T GT; Ortega, Victor E VE; Xu, Hanfei H; Fingerlin, Tasha E TE; Bossé, Yohan Y; Hao, Ke K; Joubert, Philippe P; Nickle, David C DC; Sin, Don D DD; Timens, Wim W; Furniss, Dominic D; Morris, Andrew P AP; Zondervan, Krina T KT; Hall, Ian P IP; Sayers, Ian I; Tobin, Martin D MD; Maher, Toby M TM; Cho, Michael H MH; Hunninghake, Gary M GM; Schwartz, David A DA; Yaspan, Brian L BL; Molyneaux, Philip L PL; Flores, Carlos C; Noth, Imre I; Jenkins, R Gisli RG; Wain, Louise V LV
Genome-wide association study of knee pain identifies associations with GDF5 and COL27A1 in UK Biobank.
Communications Biology
Meng, Weihua W; Adams, Mark J MJ; Palmer, Colin N A CNA; , ; Shi, Jingchunzi J; Auton, Adam A; Ryan, Kathleen A KA; Jordan, Joanne M JM; Mitchell, Braxton D BD; Jackson, Rebecca D RD; Yau, Michelle S MS; McIntosh, Andrew M AM; Smith, Blair H BH
GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures.
Nature Communications
Styrkarsdottir, Unnur U; Stefansson, Olafur A OA; Gunnarsdottir, Kristbjorg K; Thorleifsson, Gudmar G; Lund, Sigrun H SH; Stefansdottir, Lilja L; Juliusson, Kristinn K; Agustsdottir, Arna B AB; Zink, Florian F; Halldorsson, Gisli H GH; Ivarsdottir, Erna V EV; Benonisdottir, Stefania S; Jonsson, Hakon H; Gylfason, Arnaldur A; Norland, Kristjan K; Trajanoska, Katerina K; Boer, Cindy G CG; Southam, Lorraine L; Leung, Jason C S JCS; Tang, Nelson L S NLS; Kwok, Timothy C Y TCY; Lee, Jenny S W JSW; Ho, Suzanne C SC; Byrjalsen, Inger I; Center, Jacqueline R JR; Lee, Seung Hun SH; Koh, Jung-Min JM; Lohmander, L Stefan LS; Ho-Pham, Lan T LT; Nguyen, Tuan V TV; Eisman, John A JA; Woo, Jean J; Leung, Ping-C PC; Loughlin, John J; Zeggini, Eleftheria E; Christiansen, Claus C; Rivadeneira, Fernando F; van Meurs, Joyce J; Uitterlinden, Andre G AG; Mogensen, Brynjolfur B; Jonsson, Helgi H; Ingvarsson, Thorvaldur T; Sigurdsson, Gunnar G; Benediktsson, Rafn R; Sulem, Patrick P; Jonsdottir, Ingileif I; Masson, Gisli G; Holm, Hilma H; Norddahl, Gudmundur L GL; Thorsteinsdottir, Unnur U; Gudbjartsson, Daniel F DF; Stefansson, Kari K
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.
Nature Genetics
Shrine, Nick N; Guyatt, Anna L AL; Erzurumluoglu, A Mesut AM; Jackson, Victoria E VE; Hobbs, Brian D BD; Melbourne, Carl A CA; Batini, Chiara C; Fawcett, Katherine A KA; Song, Kijoung K; Sakornsakolpat, Phuwanat P; Li, Xingnan X; Boxall, Ruth R; Reeve, Nicola F NF; Obeidat, Ma'en M; Zhao, Jing Hua JH; Wielscher, Matthias M; Weiss, Stefan S; Kentistou, Katherine A KA; Cook, James P JP; Sun, Benjamin B BB; Zhou, Jian J; Hui, Jennie J; Karrasch, Stefan S; Imboden, Medea M; Harris, Sarah E SE; Marten, Jonathan J; Enroth, Stefan S; Kerr, Shona M SM; Surakka, Ida I; Vitart, Veronique V; Lehtimäki, Terho T; Allen, Richard J RJ; Bakke, Per S PS; Beaty, Terri H TH; Bleecker, Eugene R ER; Bossé, Yohan Y; Brandsma, Corry-Anke CA; Chen, Zhengming Z; Crapo, James D JD; Danesh, John J; DeMeo, Dawn L DL; Dudbridge, Frank F; Ewert, Ralf R; Gieger, Christian C; Gulsvik, Amund A; Hansell, Anna L AL; Hao, Ke K; Hoffman, Joshua D JD; Hokanson, John E JE; Homuth, Georg G; Joshi, Peter K PK; Joubert, Philippe P; Langenberg, Claudia C; Li, Xuan X; Li, Liming L; Lin, Kuang K; Lind, Lars L; Locantore, Nicholas N; Luan, Jian'an J; Mahajan, Anubha A; Maranville, Joseph C JC; Murray, Alison A; Nickle, David C DC; Packer, Richard R; Parker, Margaret M MM; Paynton, Megan L ML; Porteous, David J DJ; Prokopenko, Dmitry D; Qiao, Dandi D; Rawal, Rajesh R; Runz, Heiko H; Sayers, Ian I; Sin, Don D DD; Smith, Blair H BH; Soler Artigas, María M; Sparrow, David D; Tal-Singer, Ruth R; Timmers, Paul R H J PRHJ; Van den Berge, Maarten M; Whittaker, John C JC; Woodruff, Prescott G PG; Yerges-Armstrong, Laura M LM; Troyanskaya, Olga G OG; Raitakari, Olli T OT; Kähönen, Mika M; Polašek, Ozren O; Gyllensten, Ulf U; Rudan, Igor I; Deary, Ian J IJ; Probst-Hensch, Nicole M NM; Schulz, Holger H; James, Alan L AL; Wilson, James F JF; Stubbe, Beate B; Zeggini, Eleftheria E; Jarvelin, Marjo-Riitta MR; Wareham, Nick N; Silverman, Edwin K EK; Hayward, Caroline C; Morris, Andrew P AP; Butterworth, Adam S AS; Scott, Robert A RA; Walters, Robin G RG; Meyers, Deborah A DA; Cho, Michael H MH; Strachan, David P DP; Hall, Ian P IP; Tobin, Martin D MD; Wain, Louise V LV; ,