Publications:

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Cervid Prion Protein Polymorphisms: Role in Chronic Wasting Disease Pathogenesis.

International Journal Of Molecular Sciences

Arifin, Maria Immaculata MI; Hannaoui, Samia S; Chang, Sheng Chun SC; Thapa, Simrika S; Schatzl, Hermann M HM; Gilch, Sabine S

Publication Date: 2021-02-25

Variant appearance in text: PRNP: S170N

PubMed Link: 33668798

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• ijms-22-02271.pdf

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Insights into the Bidirectional Properties of the Sheep-Deer Prion Transmission Barrier.

Molecular Neurobiology

Harrathi, Chafik C; Fernández-Borges, Natalia N; Eraña, Hasier H; Elezgarai, Saioa R SR; Venegas, Vanessa V; Charco, Jorge M JM; Castilla, Joaquín J

Publication Date: 2019-08

Variant appearance in text: CJD: S170N

PubMed Link: 30592012

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• Main text
• 12035_2018_Article_1443.pdf

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Protein Structure and Biology: Poster Abstracts.

Prion

Publication Date: 2013

Variant appearance in text: CJD: S170N

PubMed Link: 29095079

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Implications of peptide assemblies in amyloid diseases.

Chemical Society Reviews

Ke, Pu Chun PC; Sani, Marc-Antonie MA; Ding, Feng F; Kakinen, Aleksandr A; Javed, Ibrahim I; Separovic, Frances F; Davis, Thomas P TP; Mezzenga, Raffaele R

Publication Date: 2017-10-30

Variant appearance in text: CJD: S170N

PubMed Link: 28702523

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De Novo Generation of a Unique Cervid Prion Strain Using Protein Misfolding Cyclic Amplification.

Msphere

Meyerett-Reid, Crystal C; Wyckoff, A Christy AC; Spraker, Terry T; Pulford, Bruce B; Bender, Heather H; Zabel, Mark D MD

Publication Date: 2017

Variant appearance in text: CJD: S170N

PubMed Link: 28144628

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• Main text
• mSphere.00372-16.pdf

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Cross-species transmission of CWD prions.

Prion

Kurt, Timothy D TD; Sigurdson, Christina J CJ

Publication Date: 2016

Variant appearance in text: CJD: S170N

PubMed Link: 26809254

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Human prion protein sequence elements impede cross-species chronic wasting disease transmission.

The Journal Of Clinical Investigation

Kurt, Timothy D TD; Jiang, Lin L; Fernández-Borges, Natalia N; Bett, Cyrus C; Liu, Jun J; Yang, Tom T; Spraker, Terry R TR; Castilla, Joaquín J; Eisenberg, David D; Kong, Qingzhong Q; Sigurdson, Christina J CJ

Publication Date: 2015-04

Variant appearance in text: CJD: S170N

PubMed Link: 25705888

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A proposed mechanism for the promotion of prion conversion involving a strictly conserved tyrosine residue in the β2-α2 loop of PrPC.

The Journal Of Biological Chemistry

Kurt, Timothy D TD; Jiang, Lin L; Bett, Cyrus C; Eisenberg, David D; Sigurdson, Christina J CJ

Publication Date: 2014-04-11

Variant appearance in text: PRNP: S170N

PubMed Link: 24596090

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From prion diseases to prion-like propagation mechanisms of neurodegenerative diseases.

International Journal Of Cell Biology

Acquatella-Tran Van Ba, Isabelle I; Imberdis, Thibaut T; Perrier, Véronique V

Publication Date: 2013

Variant appearance in text: CJD: S170N

PubMed Link: 24222767

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• Main text
• IJCB2013-975832.pdf

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Probing early misfolding events in prion protein mutants by NMR spectroscopy.

Molecules (Basel, Switzerland)

Giachin, Gabriele G; Biljan, Ivana I; Ilc, Gregor G; Plavec, Janez J; Legname, Giuseppe G

Publication Date: 2013-08-07

Variant appearance in text: PRNP: S170N

PubMed Link: 23966072

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Introducing a rigid loop structure from deer into mouse prion protein increases its propensity for misfolding in vitro.

Plos One

Kyle, Leah M LM; John, Theodore R TR; Schätzl, Hermann M HM; Lewis, Randolph V RV

Publication Date: 2013

Variant appearance in text: CJD: S170N

PubMed Link: 23825561

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Detection and control of prion diseases in food animals.

Isrn Veterinary Science

Hedlin, Peter P; Taschuk, Ryan R; Potter, Andrew A; Griebel, Philip P; Napper, Scott S

Publication Date: 2012

Variant appearance in text: PRNP: S170N

PubMed Link: 23738120

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The landscape of the prion protein's structural response to mutation revealed by principal component analysis of multiple NMR ensembles.

Plos Computational Biology

Gendoo, Deena M A DM; Harrison, Paul M PM

Publication Date: 2012

Variant appearance in text: CJD: S170N

PubMed Link: 22912570

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• Main text
• pcbi.1002646.pdf

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Ultra-efficient PrP(Sc) amplification highlights potentialities and pitfalls of PMCA technology.

Plos Pathogens

Cosseddu, Gian Mario GM; Nonno, Romolo R; Vaccari, Gabriele G; Bucalossi, Cecilia C; Fernandez-Borges, Natalia N; Di Bari, Michele Angelo MA; Castilla, Joaquin J; Agrimi, Umberto U

Publication Date: 2011-11

Variant appearance in text: PRNP: S170N

PubMed Link: 22114554

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• Main text
• ppat.1002370.pdf

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Strain specific resistance to murine scrapie associated with a naturally occurring human prion protein polymorphism at residue 171.

Plos Pathogens

Striebel, James F JF; Race, Brent B; Meade-White, Kimberly D KD; LaCasse, Rachel R; Chesebro, Bruce B

Publication Date: 2011-09

Variant appearance in text: CJD: S170N

PubMed Link: 21980292

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Spongiform encephalopathy in transgenic mice expressing a point mutation in the β2-α2 loop of the prion protein.

The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience

Sigurdson, Christina J CJ; Joshi-Barr, Shivanjali S; Bett, Cyrus C; Winson, Olivia O; Manco, Giuseppe G; Schwarz, Petra P; Rülicke, Thomas T; Nilsson, K Peter R KP; Margalith, Ilan I; Raeber, Alex A; Peretz, David D; Hornemann, Simone S; Wüthrich, Kurt K; Aguzzi, Adriano A

Publication Date: 2011-09-28

Variant appearance in text: PRNP: S170N

PubMed Link: 21957246

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Solution structure and dynamics of the I214V mutant of the rabbit prion protein.

Plos One

Wen, Yi Y; Li, Jun J; Xiong, Minqian M; Peng, Yu Y; Yao, Wenming W; Hong, Jing J; Lin, Donghai D

Publication Date: 2010-10-07

Variant appearance in text: CJD: S170N

PubMed Link: 20949107

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• Main text
• pone.0013273.pdf

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A molecular switch controls interspecies prion disease transmission in mice.

The Journal Of Clinical Investigation

Sigurdson, Christina J CJ; Nilsson, K Peter R KP; Hornemann, Simone S; Manco, Giuseppe G; Fernández-Borges, Natalia N; Schwarz, Petra P; Castilla, Joaquín J; Wüthrich, Kurt K; Aguzzi, Adriano A

Publication Date: 2010-07

Variant appearance in text: CJD: S170N

PubMed Link: 20551516

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Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.

The Embo Journal

Lee, Seungjoo S; Antony, Lizamma L; Hartmann, Rune R; Knaus, Karen J KJ; Surewicz, Krystyna K; Surewicz, Witold K WK; Yee, Vivien C VC

Publication Date: 2010-01-06

Variant appearance in text: CJD: S170N

PubMed Link: 19927125

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De novo mammalian prion synthesis.

Prion

Benetti, Federico F; Legname, Giuseppe G

Publication Date: 2009

Variant appearance in text: CJD: S170N

PubMed Link: 19887900

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Constraining the loop, releasing prion infectivity.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Soto, Claudio C

Publication Date: 2009-01-06

Variant appearance in text: PRNP: S170N

PubMed Link: 19118191

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De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Sigurdson, Christina J CJ; Nilsson, K Peter R KP; Hornemann, Simone S; Heikenwalder, Mathias M; Manco, Giuseppe G; Schwarz, Petra P; Ott, David D; Rülicke, Thomas T; Liberski, Pawel P PP; Julius, Christian C; Falsig, Jeppe J; Stitz, Lothar L; Wüthrich, Kurt K; Aguzzi, Adriano A

Publication Date: 2009-01-06

Variant appearance in text: PRNP: S170N

PubMed Link: 19073920

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The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes.

Plos One

Polymenidou, Magdalini M; Moos, Rita R; Scott, Mike M; Sigurdson, Christina C; Shi, Yong-Zhong YZ; Yajima, Bill B; Hafner-Bratkovic, Iva I; Jerala, Roman R; Hornemann, Simone S; Wuthrich, Kurt K; Bellon, Anne A; Vey, Martin M; Garen, Graciela G; James, Michael N G MN; Kav, Nat N; Aguzzi, Adriano A

Publication Date: 2008

Variant appearance in text: CJD: S170N

PubMed Link: 19060956

Variant Present in the following documents:

• Main text
• pone.0003872.pdf

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