Alzheimer's Amyloid β Peptide Induces Angiogenesis in an Alzheimer's Disease Model Mouse through Placental Growth Factor and Angiopoietin 2 Expressions.
International Journal Of Molecular Sciences
Sheikh, Abdullah Md AM; Yano, Shozo S; Tabassum, Shatera S; Mitaki, Shingo S; Michikawa, Makoto M; Nagai, Atsushi A
Network expansion of genetic associations defines a pleiotropy map of human cell biology.
Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23
Variant appearance in text: APP: 2149G>T; Val717Phe
Cerebral Aβ deposition in an Aβ-precursor protein-transgenic rhesus monkey.
Aging Brain
Chan, Anthony W S AWS; Cho, In Ki IK; Li, Chun-Xia CX; Zhang, Xiaodong X; Patel, Sudeep S; Rusnak, Rebecca R; Raper, Jessica J; Bachevalier, Jocelyne J; Moran, Sean P SP; Chi, Tim T; Cannon, Katherine H KH; Hunter, Carissa E CE; Martin, Ryan C RC; Xiao, Hailian H; Yang, Shang-Hsun SH; Gumber, Sanjeev S; Herndon, James G JG; Rosen, Rebecca F RF; Hu, William T WT; Lah, James J JJ; Levey, Allan I AI; Smith, Yoland Y; Walker, Lary C LC
Interdisciplinary Approaches to Deal with Alzheimer's Disease-From Bench to Bedside: What Feasible Options Do Already Exist Today?
Biomedicines
Ablinger, Irene I; Dressel, Katharina K; Rott, Thea T; Lauer, Anna Andrea AA; Tiemann, Michael M; Batista, João Pedro JP; Taddey, Tim T; Grimm, Heike Sabine HS; Grimm, Marcus Otto Walter MOW
Structural Determinant of β-Amyloid Formation: From Transmembrane Protein Dimerization to β-Amyloid Aggregates.
Biomedicines
Papadopoulos, Nicolas N; Suelves, Nuria N; Perrin, Florian F; Vadukul, Devkee M DM; Vrancx, Céline C; Constantinescu, Stefan N SN; Kienlen-Campard, Pascal P
Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease.
Nature Communications
Yang, Yun Y; Tapias, Victor V; Acosta, Diana D; Xu, Hui H; Chen, Huanlian H; Bhawal, Ruchika R; Anderson, Elizabeth T ET; Ivanova, Elena E; Lin, Hening H; Sagdullaev, Botir T BT; Chen, Jianer J; Klein, William L WL; Viola, Kirsten L KL; Gandy, Sam S; Haroutunian, Vahram V; Beal, M Flint MF; Eliezer, David D; Zhang, Sheng S; Gibson, Gary E GE
Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease.
Nature Communications
Yang, Yun Y; Tapias, Victor V; Acosta, Diana D; Xu, Hui H; Chen, Huanlian H; Bhawal, Ruchika R; Anderson, Elizabeth T ET; Ivanova, Elena E; Lin, Hening H; Sagdullaev, Botir T BT; Chen, Jianer J; Klein, William L WL; Viola, Kirsten L KL; Gandy, Sam S; Haroutunian, Vahram V; Beal, M Flint MF; Eliezer, David D; Zhang, Sheng S; Gibson, Gary E GE
Plaque-Associated Oligomeric Amyloid-Beta Drives Early Synaptotoxicity in APP/PS1 Mice Hippocampus: Ultrastructural Pathology Analysis.
Frontiers In Neuroscience
Sanchez-Varo, Raquel R; Sanchez-Mejias, Elisabeth E; Fernandez-Valenzuela, Juan Jose JJ; De Castro, Vanessa V; Mejias-Ortega, Marina M; Gomez-Arboledas, Angela A; Jimenez, Sebastian S; Sanchez-Mico, Maria Virtudes MV; Trujillo-Estrada, Laura L; Moreno-Gonzalez, Ines I; Baglietto-Vargas, David D; Vizuete, Marisa M; Davila, Jose Carlos JC; Vitorica, Javier J; Gutierrez, Antonia A
N-Methyl-D-aspartate (NMDA) and cannabinoid CB2 receptors form functional complexes in cells of the central nervous system: insights into the therapeutic potential of neuronal and microglial NMDA receptors.
Alzheimer'S Research & Therapy
Rivas-Santisteban, Rafael R; Lillo, Alejandro A; Lillo, Jaume J; Rebassa, Joan-Biel JB; Contestí, Joan S JS; Saura, Carlos A CA; Franco, Rafael R; Navarro, Gemma G
Identification and drug-induced reversion of molecular signatures of Alzheimer's disease onset and progression in AppNL-G-F, AppNL-F, and 3xTg-AD mouse models.
Genome Medicine
Pauls, Eduardo E; Bayod, Sergi S; Mateo, Lídia L; Alcalde, Víctor V; Juan-Blanco, Teresa T; Sánchez-Soto, Marta M; Saido, Takaomi C TC; Saito, Takashi T; Berrenguer-Llergo, Antoni A; Attolini, Camille Stephan-Otto CS; Gay, Marina M; de Oliveira, Eliandre E; Duran-Frigola, Miquel M; Aloy, Patrick P
Characterization of an APP/tau rat model of Alzheimer's disease by positron emission tomography and immunofluorescent labeling.
Alzheimer'S Research & Therapy
Filip, Thomas T; Mairinger, Severin S; Neddens, Joerg J; Sauberer, Michael M; Flunkert, Stefanie S; Stanek, Johann J; Wanek, Thomas T; Okamura, Nobuyuki N; Langer, Oliver O; Hutter-Paier, Birgit B; Kuntner, Claudia C
Synthesis of human amyloid restricted to liver results in an Alzheimer disease-like neurodegenerative phenotype.
Plos Biology
Lam, Virginie V; Takechi, Ryusuke R; Hackett, Mark J MJ; Francis, Roslyn R; Bynevelt, Michael M; Celliers, Liesl M LM; Nesbit, Michael M; Mamsa, Somayra S; Arfuso, Frank F; Das, Sukanya S; Koentgen, Frank F; Hagan, Maree M; Codd, Lincoln L; Richardson, Kirsty K; O'Mara, Brenton B; Scharli, Rainer K RK; Morandeau, Laurence L; Gauntlett, Jonathan J; Leatherday, Christopher C; Boucek, Jan J; Mamo, John C L JCL