Suspension TRAPping Filter (sTRAP) Sample Preparation for Quantitative Proteomics in the Low µg Input Range Using a Plasmid DNA Micro-Spin Column: Analysis of the Hippocampus from the 5xFAD Alzheimer's Disease Mouse Model.
Cells
Thanou, Evangelia E; Koopmans, Frank F; Pita-Illobre, Débora D; Klaassen, Remco V RV; Özer, Berna B; Charalampopoulos, Ioannis I; Smit, August B AB; Li, Ka Wan KW
A comparison of machine learning approaches for the quantification of microglial cells in the brain of mice, rats and non-human primates.
Plos One
Anwer, Danish M DM; Gubinelli, Francesco F; Kurt, Yunus A YA; Sarauskyte, Livija L; Jacobs, Febe F; Venuti, Chiara C; Sandoval, Ivette M IM; Yang, Yiyi Y; Stancati, Jennifer J; Mazzocchi, Martina M; Brandi, Edoardo E; O'Keeffe, Gerard G; Steece-Collier, Kathy K; Li, Jia-Yi JY; Deierborg, Tomas T; Manfredsson, Fredric P FP; Davidsson, Marcus M; Heuer, Andreas A
An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer's disease.
Nature Aging
Jiang, Yuanbing Y; Zhou, Xiaopu X; Wong, Hiu Yi HY; Ouyang, Li L; Ip, Fanny C F FCF; Chau, Vicky M N VMN; Lau, Shun-Fat SF; Wu, Wei W; Wong, Daniel Y K DYK; Seo, Heukjin H; Fu, Wing-Yu WY; Lai, Nicole C H NCH; Chen, Yuewen Y; Chen, Yu Y; Tong, Estella P S EPS; , ; Mok, Vincent C T VCT; Kwok, Timothy C Y TCY; Mok, Kin Y KY; Shoai, Maryam M; Lehallier, Benoit B; Losada, Patricia Morán PM; O'Brien, Eleanor E; Porter, Tenielle T; Laws, Simon M SM; Hardy, John J; Wyss-Coray, Tony T; Masters, Colin L CL; Fu, Amy K Y AKY; Ip, Nancy Y NY
Sex Differences between Neuronal Loss and the Early Onset of Amyloid Deposits and Behavioral Consequences in 5xFAD Transgenic Mouse as a Model for Alzheimer's Disease.
Cells
Poon, Chi Him CH; Wong, San Tung Nicholas STN; Roy, Jaydeep J; Wang, Yingyi Y; Chan, Hui Wang Hujo HWH; Steinbusch, Harry H; Blokland, Arjan A; Temel, Yasin Y; Aquili, Luca L; Lim, Lee Wei LW
Leveraging genetic diversity in mice to inform individual differences in brain microstructure and memory.
Frontiers In Behavioral Neuroscience
Murdy, Thomas J TJ; Dunn, Amy R AR; Singh, Surjeet S; Telpoukhovskaia, Maria A MA; Zhang, Shanrong S; White, Jacqueline K JK; Kahn, Itamar I; Febo, Marcelo M; Kaczorowski, Catherine C CC
Cerebral Aβ deposition in an Aβ-precursor protein-transgenic rhesus monkey.
Aging Brain
Chan, Anthony W S AWS; Cho, In Ki IK; Li, Chun-Xia CX; Zhang, Xiaodong X; Patel, Sudeep S; Rusnak, Rebecca R; Raper, Jessica J; Bachevalier, Jocelyne J; Moran, Sean P SP; Chi, Tim T; Cannon, Katherine H KH; Hunter, Carissa E CE; Martin, Ryan C RC; Xiao, Hailian H; Yang, Shang-Hsun SH; Gumber, Sanjeev S; Herndon, James G JG; Rosen, Rebecca F RF; Hu, William T WT; Lah, James J JJ; Levey, Allan I AI; Smith, Yoland Y; Walker, Lary C LC
Glial Gap Junction Pathology in the Spinal Cord of the 5xFAD Mouse Model of Early-Onset Alzheimer's Disease.
International Journal Of Molecular Sciences
Pechlivanidou, Maria M; Kousiappa, Ioanna I; Angeli, Stella S; Sargiannidou, Irene I; Koupparis, Andreas M AM; Papacostas, Savvas S SS; Kleopa, Kleopas A KA
Comprehensive analysis of dysregulated circular RNAs and construction of a ceRNA network involved in the pathology of Alzheimer's disease in a 5 × FAD mouse model.
Frontiers In Aging Neuroscience
Sun, Ting T; Zeng, Li L; Cai, Zhongdi Z; Liu, Qingshan Q; Li, Zhuorong Z; Liu, Rui R
Aryloxypropanolamine targets amyloid aggregates and reverses Alzheimer-like phenotypes in Alzheimer mouse models.
Alzheimer'S Research & Therapy
Lee, Hee Yang HY; Yoon, Soljee S; Lee, Jeong Hwa JH; Park, Keunwan K; Jung, Youngeun Y; Cho, Illhwan I; Lee, Donghee D; Shin, Jisu J; Kim, Kyeonghwan K; Kim, Sunmi S; Kim, Jimin J; Kim, Koeun K; Han, Seung Hoon SH; Kim, Seong Muk SM; Kim, Hye Ju HJ; Kim, Hye Yun HY; Kim, Ikyon I; Kim, Young Soo YS
Late-long-term potentiation magnitude, but not Aβ levels and amyloid pathology, is associated with behavioral performance in a rat knock-in model of Alzheimer disease.
Frontiers In Aging Neuroscience
Yesiltepe, Metin M; Yin, Tao T; Tambini, Marc D MD; Breuillaud, Lionel L; Zehntner, Simone P SP; D'Adamio, Luciano L
Interdisciplinary Approaches to Deal with Alzheimer's Disease-From Bench to Bedside: What Feasible Options Do Already Exist Today?
Biomedicines
Ablinger, Irene I; Dressel, Katharina K; Rott, Thea T; Lauer, Anna Andrea AA; Tiemann, Michael M; Batista, João Pedro JP; Taddey, Tim T; Grimm, Heike Sabine HS; Grimm, Marcus Otto Walter MOW
Medin co-aggregates with vascular amyloid-β in Alzheimer's disease.
Nature
Wagner, Jessica J; Degenhardt, Karoline K; Veit, Marleen M; Louros, Nikolaos N; Konstantoulea, Katerina K; Skodras, Angelos A; Wild, Katleen K; Liu, Ping P; Obermüller, Ulrike U; Bansal, Vikas V; Dalmia, Anupriya A; Häsler, Lisa M LM; Lambert, Marius M; De Vleeschouwer, Matthias M; Davies, Hannah A HA; Madine, Jillian J; Kronenberg-Versteeg, Deborah D; Feederle, Regina R; Del Turco, Domenico D; Nilsson, K Peter R KPR; Lashley, Tammaryn T; Deller, Thomas T; Gearing, Marla M; Walker, Lary C LC; Heutink, Peter P; Rousseau, Frederic F; Schymkowitz, Joost J; Jucker, Mathias M; Neher, Jonas J JJ
Branched-Chain Amino Acids Are Linked with Alzheimer's Disease-Related Pathology and Cognitive Deficits.
Cells
Siddik, Md Abu Bakkar MAB; Mullins, Caitlyn A CA; Kramer, Alyssa A; Shah, Harsh H; Gannaban, Ritchel B RB; Zabet-Moghaddam, Masoud M; Huebinger, Ryan M RM; Hegde, Vijay K VK; MohanKumar, Sheba M J SMJ; MohanKumar, Puliyur S PS; Shin, Andrew C AC