Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine.
Nature Genetics
Schlosser, Pascal P; Scherer, Nora N; Grundner-Culemann, Franziska F; Monteiro-Martins, Sara S; Haug, Stefan S; Steinbrenner, Inga I; Uluvar, Burulça B; Wuttke, Matthias M; Cheng, Yurong Y; Ekici, Arif B AB; Gyimesi, Gergely G; Karoly, Edward D ED; Kotsis, Fruzsina F; Mielke, Johanna J; Gomez, Maria F MF; Yu, Bing B; Grams, Morgan E ME; Coresh, Josef J; Boerwinkle, Eric E; Köttgen, Michael M; Kronenberg, Florian F; Meiselbach, Heike H; Mohney, Robert P RP; Akilesh, Shreeram S; , ; Schmidts, Miriam M; Hediger, Matthias A MA; Schultheiss, Ulla T UT; Eckardt, Kai-Uwe KU; Oefner, Peter J PJ; Sekula, Peggy P; Li, Yong Y; Köttgen, Anna A
Pharmacogenomic profile of actionable molecular variants related to drugs commonly used in anesthesia: WES analysis reveals new mutations.
Frontiers In Pharmacology
Parada-Márquez, Juan Fernando JF; Maldonado-Rodriguez, Nicolás David ND; Triana-Fonseca, Paula P; Contreras-Bravo, Nora Constanza NC; Calderón-Ospina, Carlos Alberto CA; Restrepo, Carlos M CM; Morel, Adrien A; Ortega-Recalde, Oscar Javier OJ; Silgado-Guzmán, Daniel Felipe DF; Angulo-Aguado, Mariana M; Fonseca-Mendoza, Dora Janeth DJ
Publication Date: 2023
Variant appearance in text: COMT: Val158Met; rs4680
Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Genetic Influences on the Developing Young Brain and Risk for Neuropsychiatric Disorders.
Biological Psychiatry
Alex, Ann M AM; Buss, Claudia C; Davis, Elysia Poggi EP; Campos, Gustavo de Los GL; Donald, Kirsten A KA; Fair, Damien A DA; Gaab, Nadine N; Gao, Wei W; Gilmore, John H JH; Girault, Jessica B JB; Grewen, Karen K; Groenewold, Nynke A NA; Hankin, Benjamin L BL; Ipser, Jonathan J; Kapoor, Shreya S; Kim, Pilyoung P; Lin, Weili W; Luo, Shan S; Norton, Elizabeth S ES; O'Connor, Thomas G TG; Piven, Joseph J; Qiu, Anqi A; Rasmussen, Jerod M JM; Skeide, Michael A MA; Stein, Dan J DJ; Styner, Martin A MA; Thompson, Paul M PM; Wakschlag, Laurie L; Knickmeyer, Rebecca R; ,
A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Jang, H Josh HJ; Hostetter, Galen G; MacFarlane, Alexander W AW; Madaj, Zachary Z; Ross, Eric A EA; Hinoue, Toshinori T; Kulchycki, Justin R JR; Burgos, Ryan S RS; Tafseer, Mahvish M; Alpaugh, R Katherine RK; Schwebel, Candice L CL; Kokate, Rutika R; Geynisman, Daniel M DM; Zibelman, Matthew R MR; Ghatalia, Pooja P; Nichols, Peter W PW; Chung, Woonbok W; Madzo, Jozef J; Hahn, Noah M NM; Quinn, David I DI; Issa, Jean-Pierre J JJ; Topper, Michael J MJ; Baylin, Stephen B SB; Shen, Hui H; Campbell, Kerry S KS; Jones, Peter A PA; Plimack, Elizabeth R ER
Effect of common OPRM1, COMT, SLC6A4, ABCB1, and CYP2B6 polymorphisms on perioperative analgesic and propofol demands on patients subjected to thyroidectomy surgery.
Multidimensional evaluation of the pain profile as prognostic factor in individuals with hip or knee osteoarthritis receiving total joint replacement: protocol of a 2-year longitudinal prognostic cohort study.
Bmj Open
Florencio, Lidiane L LL; Palacios-Ceña, María M; Fuensalida-Novo, Stella S; de-la-Llave-Rincón, Ana I AI; Ambite-Quesada, Silvia S; Ortega-Santiago, Ricardo R; Arias-Buría, José L JL; Cigarán-Méndez, Margarita M; Arendt-Nielsen, Lars L; Fernández-de-Las-Peñas, César C
Genetic Addiction Risk and Psychological Profiling Analyses for "Preaddiction" Severity Index.
Journal Of Personalized Medicine
Blum, Kenneth K; Han, David D; Bowirrat, Abdalla A; Downs, Bernard William BW; Bagchi, Debasis D; Thanos, Panayotis K PK; Baron, David D; Braverman, Eric R ER; Dennen, Catherine A CA; Gupta, Ashim A; Elman, Igor I; Badgaiyan, Rajendra D RD; Llanos-Gomez, Luis L; Khalsa, Jag J; Barh, Debmalya D; McLaughlin, Thomas T; Gold, Mark S MS
Publication Date: 2022-10-27
Variant appearance in text: COMT: Val158Met; rs4680
Effects of dopamine D2/3 and opioid receptor antagonism on the trade-off between model-based and model-free behaviour in healthy volunteers.
Elife
Mikus, Nace N; Korb, Sebastian S; Massaccesi, Claudia C; Gausterer, Christian C; Graf, Irene I; Willeit, Matthäus M; Eisenegger, Christoph C; Lamm, Claus C; Silani, Giorgia G; Mathys, Christoph C
Publication Date: 2022-12-05
Variant appearance in text: COMT: Val158Met; rs4680
Pain predict genetics: protocol for a prospective observational study of clinical and genetic factors to predict the development of postoperative pain.
Bmj Open
Li, Song S; van Boekel, Regina L M RLM; van den Heuvel, Sandra A S SAS; Coenen, Marieke J H MJH; Vissers, Kris C P KCP
Comparative Genomic Hybridization and Transcriptome Sequencing Reveal Genes with Gain in Acute Lymphoblastic Leukemia: JUP Expression Emerges as a Survival-Related Gene.
Diagnostics (Basel, Switzerland)
Zapata-García, Jessica Alejandra JA; Riveros-Magaña, Alma Rocío AR; Ortiz-Lazareno, Pablo Cesar PC; Hernández-Flores, Georgina G; Jave-Suárez, Luis Felipe LF; Aguilar-Lemarroy, Adriana A