A Missense Variant in COMT Associated with Hearing Loss among Young Adults: The National Longitudinal Study of Adolescent to Adult Health (Add Health).
Biomedicines
Li, Chuan-Ming CM; Chen, Le L; Chen, Guanjie G; Zhang, Jianhua J; Hoffman, Howard J HJ
Genetic variations in catechol-O-methyltransferase gene are associated with levodopa response variability in Chinese patients with Parkinson's disease.
Influence of Genetic Variation in COMT on Cisplatin-Induced Nephrotoxicity in Cancer Patients.
Genes
Agema, Bram C BC; Koolen, Stijn L W SLW; With, Mirjam de M; Doorn, Nadia van NV; Heersche, Niels N; Hoop, Esther Oomen-de EO; Visser, Sabine S; Aerts, Joachim G J V JGJV; Bins, Sander S; Schaik, Ron H N van RHNV; Mathijssen, Ron H J RHJ
Genetic Variants as Predictive Markers for Ototoxicity and Nephrotoxicity in Patients with Locally Advanced Head and Neck Cancer Treated with Cisplatin-Containing Chemoradiotherapy (The PRONE Study).
Cancers
Driessen, Chantal M CM; Ham, Janneke C JC; Te Loo, Maroeska M; van Meerten, Esther E; van Lamoen, Maurits M; Hakobjan, Marina H MH; Takes, Robert P RP; van der Graaf, Winette T WT; Kaanders, Johannes H JH; Coenen, Marieke J H MJH; van Herpen, Carla M CM
The genetic vulnerability to cisplatin ototoxicity: a systematic review.
Scientific Reports
Tserga, Evangelia E; Nandwani, Tara T; Edvall, Niklas K NK; Bulla, Jan J; Patel, Poulam P; Canlon, Barbara B; Cederroth, Christopher R CR; Baguley, David M DM
Analytical Validation of Variants to Aid in Genotype-Guided Therapy for Oncology.
The Journal Of Molecular Diagnostics : Jmd
Swart, Marelize M; Stansberry, Wesley M WM; Pratt, Victoria M VM; Medeiros, Elizabeth B EB; Kiel, Patrick J PJ; Shen, Fei F; Schneider, Bryan P BP; Skaar, Todd C TC
Publication Date: 2019-05
Variant appearance in text: COMT: 615+310C>T; rs4646316
TPMT, COMT and ACYP2 genetic variants in paediatric cancer patients with cisplatin-induced ototoxicity.
Pharmacogenetics And Genomics
Thiesen, Signe S; Yin, Peng P; Jorgensen, Andrea L AL; Zhang, Jieying Eunice JE; Manzo, Valentina V; McEvoy, Laurence L; Barton, Christopher C; Picton, Susan S; Bailey, Simon S; Brock, Penelope P; Vyas, Harish H; Walker, David D; Makin, Guy G; Bandi, Srinivas S; Pizer, Barry B; Hawcutt, Daniel B DB; Pirmohamed, Munir M
Pharmacogenomics in Pediatric Patients: Towards Personalized Medicine.
Paediatric Drugs
Maagdenberg, Hedy H; Vijverberg, Susanne J H SJ; Bierings, Marc B MB; Carleton, Bruce C BC; Arets, Hubertus G M HG; de Boer, Anthonius A; Maitland-van der Zee, Anke H AH
COMT, BDNF, and DTNBP1 polymorphisms and cognitive functions in patients with brain tumors.
Neuro-Oncology
Correa, Denise D DD; Satagopan, Jaya J; Cheung, Kenneth K; Arora, Arshi K AK; Kryza-Lacombe, Maria M; Xu, Youming Y; Karimi, Sasan S; Lyo, John J; DeAngelis, Lisa M LM; Orlow, Irene I
Genetic assessment of additional endophenotypes from the Consortium on the Genetics of Schizophrenia Family Study.
Schizophrenia Research
Greenwood, Tiffany A TA; Lazzeroni, Laura C LC; Calkins, Monica E ME; Freedman, Robert R; Green, Michael F MF; Gur, Raquel E RE; Gur, Ruben C RC; Light, Gregory A GA; Nuechterlein, Keith H KH; Olincy, Ann A; Radant, Allen D AD; Seidman, Larry J LJ; Siever, Larry J LJ; Silverman, Jeremy M JM; Stone, William S WS; Sugar, Catherine A CA; Swerdlow, Neal R NR; Tsuang, Debby W DW; Tsuang, Ming T MT; Turetsky, Bruce I BI; Braff, David L DL
COMT and MAO-A polymorphisms and obsessive-compulsive disorder: a family-based association study.
Plos One
Sampaio, Aline Santos AS; Hounie, Ana Gabriela AG; Petribú, Kátia K; Cappi, Carolina C; Morais, Ivanil I; Vallada, Homero H; do Rosário, Maria Conceição MC; Stewart, S Evelyn SE; Fargeness, Jesen J; Mathews, Carol C; Arnold, Paul P; Hanna, Gregory L GL; Richter, Margaret M; Kennedy, James J; Fontenelle, Leonardo L; de Bragança Pereira, Carlos Alberto CA; Pauls, David L DL; Miguel, Eurípedes Constantino EC
Influence of genetic variants in TPMT and COMT associated with cisplatin induced hearing loss in patients with cancer: two new cohorts and a meta-analysis reveal significant heterogeneity between cohorts.
Plos One
Hagleitner, Melanie M MM; Coenen, Marieke J H MJ; Patino-Garcia, Ana A; de Bont, Eveline S J M ES; Gonzalez-Neira, Anna A; Vos, Hanneke I HI; van Leeuwen, Frank N FN; Gelderblom, Hans H; Hoogerbrugge, Peter M PM; Guchelaar, Henk-Jan HJ; Te Loo, Maroeska W M MW
Effect of catechol-o-methyltransferase-gene (COMT) variants on experimental and acute postoperative pain in 1,000 women undergoing surgery for breast cancer.
Anesthesiology
Kambur, Oleg O; Kaunisto, Mari A MA; Tikkanen, Emmi E; Leal, Suzanne M SM; Ripatti, Samuli S; Kalso, Eija A EA
The role of inherited TPMT and COMT genetic variation in cisplatin-induced ototoxicity in children with cancer.
Clinical Pharmacology And Therapeutics
Yang, J J JJ; Lim, J Y S JY; Huang, J J; Bass, J J; Wu, J J; Wang, C C; Fang, J J; Stewart, E E; Harstead, E H EH; E, S S; Robinson, G W GW; Evans, W E WE; Pappo, A A; Zuo, J J; Relling, M V MV; Onar-Thomas, A A; Gajjar, A A; Stewart, C F CF
Replication of TPMT and ABCC3 genetic variants highly associated with cisplatin-induced hearing loss in children.
Clinical Pharmacology And Therapeutics
Pussegoda, K K; Ross, C J CJ; Visscher, H H; Yazdanpanah, M M; Brooks, B B; Rassekh, S R SR; Zada, Y F YF; Dubé, M-P MP; Carleton, B C BC; Hayden, M R MR; ,
Chemotherapy refractory testicular germ cell tumor is associated with a variant in Armadillo Repeat gene deleted in Velco-Cardio-Facial syndrome (ARVCF).
Frontiers In Endocrinology
Fung, Chunkit C; Vaughn, David J DJ; Mitra, Nandita N; Ciosek, Stephanie L SL; Vardhanabhuti, Saran S; Nathanson, Katherine L KL; Kanetsky, Peter A PA
Interaction of early environment, gender and genes of monoamine neurotransmission in the aetiology of depression in a large population-based Finnish birth cohort.
Bmj Open
Nyman, Emma S ES; Sulkava, Sonja S; Soronen, Pia P; Miettunen, Jouko J; Loukola, Anu A; Leppä, Virpi V; Joukamaa, Matti M; Mäki, Pirjo P; Järvelin, Marjo-Riitta MR; Freimer, Nelson N; Peltonen, Leena L; Veijola, Juha J; Paunio, Tiina T
Association between polymorphisms in catechol-O-methyltransferase (COMT) and cocaine-induced paranoia in European-American and African-American populations.
American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics
Ittiwut, Rungnapa R; Listman, Jennifer B JB; Ittiwut, Chupong C; Cubells, Joseph F JF; Weiss, Roger D RD; Brady, Kathleen K; Oslin, David D; Farrer, Lindsay A LA; Kranzler, Henry R HR; Gelernter, Joel J
Association of COMT haplotypes and breast cancer risk in caucasian women.
Anticancer Research
Peterson, Neeraja B NB; Trentham-Dietz, Amy A; Garcia-Closas, Montserrat M; Newcomb, Polly A PA; Titus-Ernstoff, Linda L; Huang, Yifan Y; Chanock, Stephen J SJ; Haines, Jonathan L JL; Egan, Kathleen M KM
A reappraisal of the association between Dysbindin (DTNBP1) and schizophrenia in a large combined case-control and family-based sample of German ancestry.
Schizophrenia Research
Strohmaier, Jana J; Frank, Josef J; Wendland, Jens R JR; Schumacher, Johannes J; Jamra, Rami Abou RA; Treutlein, Jens J; Nieratschker, Vanessa V; Breuer, René R; Mattheisen, Manuel M; Herms, Stefan S; Mühleisen, Thomas W TW; Maier, Wolfgang W; Nöthen, Markus M MM; Cichon, Sven S; Rietschel, Marcella M; Schulze, Thomas G TG
Sexually dimorphic effects of four genes (COMT, SLC6A2, MAOA, SLC6A4) in genetic associations of ADHD: a preliminary study.
American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics
Biederman, Joseph J; Kim, Jang Woo JW; Doyle, Alysa E AE; Mick, Eric E; Fagerness, Jesen J; Smoller, Jordan W JW; Faraone, Stephen V SV