COMT c.652_653delinsTG ;(p.A218C)

Variant ID: 22-19956095-GC-TG

NM_000754.3(COMT):c.652_653delinsTG;(p.A218C)

This variant was identified in 25 publications

View GRCh38 version.




Publications:


Biotechnical development of genetic addiction risk score (GARS) and selective evidence for inclusion of polymorphic allelic risk in substance use disorder (SUD).

Journal Of Systems And Integrative Neuroscience
Blum, K K; Bowirrat, A A; Baron, D D; Lott, L L; Ponce, J V JV; Brewer, R R; Siwicki, D D; Boyett, B B; Gondre-Lewis, M C MC; Smith, D E DE; Panayotis K, Thanos T; Badgaiyan, S S; Hauser, M M; Fried, L L; A, Roy R; Downs, B W BW; Badgaiyan, R D RD
Publication Date: 2020-08

Variant appearance in text: COMT: A218C
PubMed Link: 33614164
Variant Present in the following documents:
  • Main text
  • nihms-1597218.pdf
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Genetic Biomarkers of Panic Disorder: A Systematic Review.

Genes
Tretiakov, Artemii A; Malakhova, Alena A; Naumova, Elena E; Rudko, Olga O; Klimov, Eugene E
Publication Date: 2020-11-04

Variant appearance in text: COMT: A218C
PubMed Link: 33158196
Variant Present in the following documents:
  • Main text
  • genes-11-01310.pdf
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Childhood-Onset Schizophrenia: A Systematic Overview of Its Genetic Heterogeneity From Classical Studies to the Genomic Era.

Frontiers In Genetics
Fernandez, Arnaud A; Drozd, Malgorzata Marta MM; Thümmler, Susanne S; Dor, Emmanuelle E; Capovilla, Maria M; Askenazy, Florence F; Bardoni, Barbara B
Publication Date: 2019

Variant appearance in text: COMT: A218C
PubMed Link: 31921276
Variant Present in the following documents:
  • Main text
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Biological Aspects of Aggression and Violence in Schizophrenia.

Clinical Psychopharmacology And Neuroscience : The Official Scientific Journal Of The Korean College Of Neuropsychopharmacology
Cho, WonKyung W; Shin, Won-Suk WS; An, Iseul I; Bang, Minji M; Cho, Doo-Yeoun DY; Lee, Sang-Hyuk SH
Publication Date: 2019-11-20

Variant appearance in text: COMT: A218C
PubMed Link: 31671484
Variant Present in the following documents:
  • Main text
  • cpn-17-475.pdf
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Interactions Between Variation in Candidate Genes and Environmental Factors in the Etiology of Schizophrenia and Bipolar Disorder: a Systematic Review.

Molecular Neurobiology
Misiak, Błażej B; Stramecki, Filip F; Gawęda, Łukasz Ł; Prochwicz, Katarzyna K; Sąsiadek, Maria M MM; Moustafa, Ahmed A AA; Frydecka, Dorota D
Publication Date: 2018-06

Variant appearance in text: COMT: A218C
PubMed Link: 28822116
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetics of Aggression in Alzheimer's Disease (AD).

Frontiers In Aging Neuroscience
Lukiw, Walter J WJ; Rogaev, Evgeny I EI
Publication Date: 2017

Variant appearance in text: COMT: A218C
PubMed Link: 28443016
Variant Present in the following documents:
  • fnagi-09-00087.pdf
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The Life Span Model of Suicide and Its Neurobiological Foundation.

Frontiers In Neuroscience
Ludwig, Birgit B; Roy, Bhaskar B; Wang, Qingzhong Q; Birur, Badari B; Dwivedi, Yogesh Y
Publication Date: 2017

Variant appearance in text: COMT: A218C
PubMed Link: 28261051
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic Vulnerability as a Distal Risk Factor for Suicidal Behaviour: Historical Perspective and Current Knowledge.

Zdravstveno Varstvo
Andriessen, Karl K; Videtic-Paska, Alja A
Publication Date: 2015-09

Variant appearance in text: COMT: A218C
PubMed Link: 27646732
Variant Present in the following documents:
  • Main text
  • sjph-54-03-238.pdf
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Magnetic Resonance Imaging Measures of Brain Structure to Predict Antidepressant Treatment Outcome in Major Depressive Disorder.

Ebiomedicine
Korgaonkar, Mayuresh S MS; Rekshan, William W; Gordon, Evian E; Rush, A John AJ; Williams, Leanne M LM; Blasey, Christine C; Grieve, Stuart M SM
Publication Date: 2015-01

Variant appearance in text: COMT: A218C
PubMed Link: 26137532
Variant Present in the following documents:
  • mmc2.pdf
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Advances in molecular genetic studies of attention deficit hyperactivity disorder in China.

Shanghai Archives Of Psychiatry
Gao, Qian Q; Liu, Lu L; Qian, Qiujin Q; Wang, Yufeng Y
Publication Date: 2014-08

Variant appearance in text: COMT: A218C
PubMed Link: 25317006
Variant Present in the following documents:
  • Main text
  • sap-26-04-194.pdf
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Toward a biosignature for suicide.

The American Journal Of Psychiatry
Oquendo, Maria A MA; Sullivan, Gregory M GM; Sudol, Katherin K; Baca-Garcia, Enrique E; Stanley, Barbara H BH; Sublette, M Elizabeth ME; Mann, J John JJ
Publication Date: 2014-12-01

Variant appearance in text: COMT: A218C
PubMed Link: 25263730
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of TPH-1 and TPH-2 gene polymorphisms with suicidal behavior: a systematic review and meta-analysis.

Bmc Psychiatry
González-Castro, Thelma Beatriz TB; Juárez-Rojop, Isela I; López-Narváez, María Lilia ML; Tovilla-Zárate, Carlos Alfonso CA
Publication Date: 2014-07-08

Variant appearance in text: COMT: A218C
PubMed Link: 25005534
Variant Present in the following documents:
  • 1471-244X-14-196.pdf
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The association of attempted suicide with genetic variants in the SLC6A4 and TPH genes depends on the definition of suicidal behavior: a systematic review and meta-analysis.

Translational Psychiatry
Clayden, R C RC; Zaruk, A A; Meyre, D D; Thabane, L L; Samaan, Z Z
Publication Date: 2012-10-02

Variant appearance in text: COMT: A218C
PubMed Link: 23032942
Variant Present in the following documents:
View BVdb publication page



Genetic biomarkers of depression.

Indian Journal Of Human Genetics
Tamatam, Anand A; Khanum, Farhath F; Bawa, Amarinder Singh AS
Publication Date: 2012-01

Variant appearance in text: COMT: A218C
PubMed Link: 22754217
Variant Present in the following documents:
  • Main text
View BVdb publication page



Behavioral and pharmacogenetics of aggressive behavior.

Current Topics In Behavioral Neurosciences
Takahashi, Aki A; Quadros, Isabel M IM; de Almeida, Rosa M M RM; Miczek, Klaus A KA
Publication Date: 2012

Variant appearance in text: COMT: A218C
PubMed Link: 22297576
Variant Present in the following documents:
  • Main text
View BVdb publication page



Behavioural genetics of Alzheimer's disease: a comprehensive review.

Archives Of Medical Science : Ams
Flirski, Marcin M; Sobow, Tomasz T; Kloszewska, Iwona I
Publication Date: 2011-04

Variant appearance in text: COMT: A218C
PubMed Link: 22291757
Variant Present in the following documents:
  • AMS-7-2-195.pdf
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Potential genetic risk factors for chronic TMD: genetic associations from the OPPERA case control study.

The Journal Of Pain
Smith, Shad B SB; Maixner, Dylan W DW; Greenspan, Joel D JD; Dubner, Ronald R; Fillingim, Roger B RB; Ohrbach, Richard R; Knott, Charles C; Slade, Gary D GD; Bair, Eric E; Gibson, Dustin G DG; Zaykin, Dmitri V DV; Weir, Bruce S BS; Maixner, William W; Diatchenko, Luda L
Publication Date: 2011-11

Variant appearance in text: COMT: A218C
PubMed Link: 22074755
Variant Present in the following documents:
  • Main text
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Neurobiology of aggression and violence in schizophrenia.

Schizophrenia Bulletin
Soyka, Michael M
Publication Date: 2011-09

Variant appearance in text: COMT: A218C
PubMed Link: 21860037
Variant Present in the following documents:
  • Main text
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International Study to Predict Optimized Treatment for Depression (iSPOT-D), a randomized clinical trial: rationale and protocol.

Trials
Williams, Leanne M LM; Rush, A John AJ; Koslow, Stephen H SH; Wisniewski, Stephen R SR; Cooper, Nicholas J NJ; Nemeroff, Charles B CB; Schatzberg, Alan F AF; Gordon, Evian E
Publication Date: 2011-01-05

Variant appearance in text: COMT: A218C
PubMed Link: 21208417
Variant Present in the following documents:
  • Main text
  • 1745-6215-12-4.pdf
View BVdb publication page



Molecular genetics of attention deficit hyperactivity disorder.

The Psychiatric Clinics Of North America
Faraone, Stephen V SV; Mick, Eric E
Publication Date: 2010-03

Variant appearance in text: COMT: A218C
PubMed Link: 20159345
Variant Present in the following documents:
  • Main text
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COMT but not serotonin-related genes modulates the influence of childhood abuse on anger traits.

Genes, Brain, And Behavior
Perroud, N N; Jaussent, I I; Guillaume, S S; Bellivier, F F; Baud, P P; Jollant, F F; Leboyer, M M; Lewis, C M CM; Malafosse, A A; Courtet, P P
Publication Date: 2010-03-01

Variant appearance in text: COMT: A218C
PubMed Link: 20002200
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecular epidemiology of major depressive disorder.

Environmental Health And Preventive Medicine
Kiyohara, Chikako C; Yoshimasu, Kouichi K
Publication Date: 2009-03

Variant appearance in text: COMT: A218C
PubMed Link: 19568851
Variant Present in the following documents:
  • Main text
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Pharmacogenetics of antidepressant response: an update.

Human Genomics
Drago, Antonio A; De Ronchi, Diana D; Serretti, Alessandro A
Publication Date: 2009-04

Variant appearance in text: COMT: A218C
PubMed Link: 19403460
Variant Present in the following documents:
  • Main text
View BVdb publication page



Predictors, moderators, and mediators (correlates) of treatment outcome in major depressive disorder.

Dialogues In Clinical Neuroscience
Papakostas, George I GI; Fava, Maurizio M
Publication Date: 2008

Variant appearance in text: COMT: A218C
PubMed Link: 19170401
Variant Present in the following documents:
  • Main text
  • DialoguesClinNeurosci-10-439.pdf
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Candidate genes for antidepressant response to selective serotonin reuptake inhibitors.

Neuropsychiatric Disease And Treatment
Lotrich, Francis E FE; Pollock, Bruce G BG
Publication Date: 2005-03

Variant appearance in text: COMT: A218C
PubMed Link: 18568127
Variant Present in the following documents:
  • Main text
View BVdb publication page