Genetic and Clinical Factors Associated with Olokizumab Treatment in Russian Patients with Rheumatoid Arthritis.
Journal Of Personalized Medicine
Mikhaylenko, Dmitry S DS; Kuznetsova, Ekaterina B EB; Musatova, Viktoria V VV; Bure, Irina V IV; Deryagina, Tatiana A TA; Alekseeva, Ekaterina A EA; Tarasov, Vadim V VV; Zamyatnin, Andrey A AA; Nemtsova, Marina V MV
Characterization of Rheumatoid Arthritis Risk-Associated SNPs and Identification of Novel Therapeutic Sites Using an In-Silico Approach.
Biology
Akhtar, Mehran M; Ali, Yasir Y; Islam, Zia-Ul ZU; Arshad, Maria M; Rauf, Mamoona M; Ali, Muhammad M; Maodaa, Saleh N SN; Al-Farraj, Saleh A SA; El-Serehy, Hamed A HA; Jalil, Fazal F
Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes.
Nature Genetics
Robertson, Catherine C CC; Inshaw, Jamie R J JRJ; Onengut-Gumuscu, Suna S; Chen, Wei-Min WM; Santa Cruz, David Flores DF; Yang, Hanzhi H; Cutler, Antony J AJ; Crouch, Daniel J M DJM; Farber, Emily E; Bridges, S Louis SL; Edberg, Jeffrey C JC; Kimberly, Robert P RP; Buckner, Jane H JH; Deloukas, Panos P; Divers, Jasmin J; Dabelea, Dana D; Lawrence, Jean M JM; Marcovina, Santica S; Shah, Amy S AS; Greenbaum, Carla J CJ; Atkinson, Mark A MA; Gregersen, Peter K PK; Oksenberg, Jorge R JR; Pociot, Flemming F; Rewers, Marian J MJ; Steck, Andrea K AK; Dunger, David B DB; , ; Wicker, Linda S LS; Concannon, Patrick P; Todd, John A JA; Rich, Stephen S SS
Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes.
Nature Genetics
Robertson, Catherine C CC; Inshaw, Jamie R J JRJ; Onengut-Gumuscu, Suna S; Chen, Wei-Min WM; Santa Cruz, David Flores DF; Yang, Hanzhi H; Cutler, Antony J AJ; Crouch, Daniel J M DJM; Farber, Emily E; Bridges, S Louis SL; Edberg, Jeffrey C JC; Kimberly, Robert P RP; Buckner, Jane H JH; Deloukas, Panos P; Divers, Jasmin J; Dabelea, Dana D; Lawrence, Jean M JM; Marcovina, Santica S; Shah, Amy S AS; Greenbaum, Carla J CJ; Atkinson, Mark A MA; Gregersen, Peter K PK; Oksenberg, Jorge R JR; Pociot, Flemming F; Rewers, Marian J MJ; Steck, Andrea K AK; Dunger, David B DB; , ; Wicker, Linda S LS; Concannon, Patrick P; Todd, John A JA; Rich, Stephen S SS
Genetic Factors of Predisposition and Clinical Characteristics of Rheumatoid Arthritis in Russian Patients.
Journal Of Personalized Medicine
Vetchinkina, Ekaterina A EA; Mikhaylenko, Dmitry S DS; Kuznetsova, Ekaterina B EB; Deryagina, Tatiana A TA; Alekseeva, Ekaterina A EA; Bure, Irina V IV; Zamyatnin, Andrey A AA; Nemtsova, Marina V MV
Germline Variation in PDCD1 Is Associated with Overall Survival in Patients with Metastatic Melanoma Treated with Anti-PD-1 Monotherapy.
Cancers
de With, Mirjam M; Hurkmans, Daan P DP; Oomen-de Hoop, Esther E; Lalouti, Ayoub A; Bins, Sander S; El Bouazzaoui, Samira S; van Brakel, Mandy M; Debets, Reno R; Aerts, Joachim G J V JGJV; van Schaik, Ron H N RHN; Mathijssen, Ron H J RHJ; van der Veldt, Astrid A M AAM
A population-based case-control study of genetic variation in cytokine genes associated with risk of cervical and vulvar cancers.
Gynecologic Oncology
Hardikar, Sheetal S; Johnson, Lisa G LG; Malkki, Mari M; Petersdorf, Effie W EW; Galloway, Denise A DA; Schwartz, Stephen M SM; Madeleine, Margaret M MM
Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.
Arthritis & Rheumatology (Hoboken, N.J.)
Orozco, Gisela G; Viatte, Sebastien S; Bowes, John J; Martin, Paul P; Wilson, Anthony G AG; Morgan, Ann W AW; Steer, Sophia S; Wordsworth, Paul P; Hocking, Lynne J LJ; , ; , ; , ; Barton, Anne A; Worthington, Jane J; Eyre, Stephen S
Integrated enrichment analysis of variants and pathways in genome-wide association studies indicates central role for IL-2 signaling genes in type 1 diabetes, and cytokine signaling genes in Crohn's disease.
Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking.
Plos Genetics
Scott, Ian C IC; Seegobin, Seth D SD; Steer, Sophia S; Tan, Rachael R; Forabosco, Paola P; Hinks, Anne A; Eyre, Stephen S; Morgan, Ann W AW; Wilson, Anthony G AG; Hocking, Lynne J LJ; Wordsworth, Paul P; Barton, Anne A; Worthington, Jane J; Cope, Andrew P AP; Lewis, Cathryn M CM
Genetic association analyses of atopic illness and proinflammatory cytokine genes with type 1 diabetes.
Diabetes/Metabolism Research And Reviews
Saleh, Nada M NM; Raj, Srilakshmi M SM; Smyth, Deborah J DJ; Wallace, Chris C; Howson, Joanna M M JM; Bell, Louise L; Walker, Neil M NM; Stevens, Helen E HE; Todd, John A JA
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.
Nature Genetics
Stahl, Eli A EA; Raychaudhuri, Soumya S; Remmers, Elaine F EF; Xie, Gang G; Eyre, Stephen S; Thomson, Brian P BP; Li, Yonghong Y; Kurreeman, Fina A S FA; Zhernakova, Alexandra A; Hinks, Anne A; Guiducci, Candace C; Chen, Robert R; Alfredsson, Lars L; Amos, Christopher I CI; Ardlie, Kristin G KG; , ; Barton, Anne A; Bowes, John J; Brouwer, Elisabeth E; Burtt, Noel P NP; Catanese, Joseph J JJ; Coblyn, Jonathan J; Coenen, Marieke J H MJ; Costenbader, Karen H KH; Criswell, Lindsey A LA; Crusius, J Bart A JB; Cui, Jing J; de Bakker, Paul I W PI; De Jager, Philip L PL; Ding, Bo B; Emery, Paul P; Flynn, Edward E; Harrison, Pille P; Hocking, Lynne J LJ; Huizinga, Tom W J TW; Kastner, Daniel L DL; Ke, Xiayi X; Lee, Annette T AT; Liu, Xiangdong X; Martin, Paul P; Morgan, Ann W AW; Padyukov, Leonid L; Posthumus, Marcel D MD; Radstake, Timothy R D J TR; Reid, David M DM; Seielstad, Mark M; Seldin, Michael F MF; Shadick, Nancy A NA; Steer, Sophia S; Tak, Paul P PP; Thomson, Wendy W; van der Helm-van Mil, Annette H M AH; van der Horst-Bruinsma, Irene E IE; van der Schoot, C Ellen CE; van Riel, Piet L C M PL; Weinblatt, Michael E ME; Wilson, Anthony G AG; Wolbink, Gert Jan GJ; Wordsworth, B Paul BP; , ; Wijmenga, Cisca C; Karlson, Elizabeth W EW; Toes, Rene E M RE; de Vries, Niek N; Begovich, Ann B AB; Worthington, Jane J; Siminovitch, Katherine A KA; Gregersen, Peter K PK; Klareskog, Lars L; Plenge, Robert M RM
Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy.
Arthritis And Rheumatism
Cui, Jing J; Saevarsdottir, Saedis S; Thomson, Brian B; Padyukov, Leonid L; van der Helm-van Mil, Annette H M AH; Nititham, Joanne J; Hughes, Laura B LB; de Vries, Niek N; Raychaudhuri, Soumya S; Alfredsson, Lars L; Askling, Johan J; Wedrén, Sara S; Ding, Bo B; Guiducci, Candace C; Wolbink, Gert Jan GJ; Crusius, J Bart A JB; van der Horst-Bruinsma, Irene E IE; Herenius, Marieke M; Weinblatt, Michael E ME; Shadick, Nancy A NA; Worthington, Jane J; Batliwalla, Franak F; Kern, Marlena M; Morgan, Ann W AW; Wilson, Anthony G AG; Isaacs, John D JD; Hyrich, Kimme K; Seldin, Michael F MF; Moreland, Larry W LW; Behrens, Timothy W TW; Allaart, Cornelia F CF; Criswell, Lindsey A LA; Huizinga, Tom W J TW; Tak, Paul P PP; Bridges, S Louis SL; Toes, Rene E M RE; Barton, Anne A; Klareskog, Lars L; Gregersen, Peter K PK; Karlson, Elizabeth W EW; Plenge, Robert M RM
Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk.
Nature Genetics
Raychaudhuri, Soumya S; Thomson, Brian P BP; Remmers, Elaine F EF; Eyre, Stephen S; Hinks, Anne A; Guiducci, Candace C; Catanese, Joseph J JJ; Xie, Gang G; Stahl, Eli A EA; Chen, Robert R; Alfredsson, Lars L; Amos, Christopher I CI; Ardlie, Kristin G KG; , ; Barton, Anne A; Bowes, John J; Burtt, Noel P NP; Chang, Monica M; Coblyn, Jonathan J; Costenbader, Karen H KH; Criswell, Lindsey A LA; Crusius, J Bart A JB; Cui, Jing J; De Jager, Phillip L PL; Ding, Bo B; Emery, Paul P; Flynn, Edward E; Harrison, Pille P; Hocking, Lynne J LJ; Huizinga, Tom W J TW; Kastner, Daniel L DL; Ke, Xiayi X; Kurreeman, Fina A S FA; Lee, Annette T AT; Liu, Xiangdong X; Li, Yonghong Y; Martin, Paul P; Morgan, Ann W AW; Padyukov, Leonid L; Reid, David M DM; Seielstad, Mark M; Seldin, Michael F MF; Shadick, Nancy A NA; Steer, Sophia S; Tak, Paul P PP; Thomson, Wendy W; van der Helm-van Mil, Annette H M AH; van der Horst-Bruinsma, Irene E IE; Weinblatt, Michael E ME; Wilson, Anthony G AG; Wolbink, Gert Jan GJ; Wordsworth, Paul P; , ; Altshuler, David D; Karlson, Elizabeth W EW; Toes, Rene E M RE; de Vries, Niek N; Begovich, Ann B AB; Siminovitch, Katherine A KA; Worthington, Jane J; Klareskog, Lars L; Gregersen, Peter K PK; Daly, Mark J MJ; Plenge, Robert M RM
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.
Nature Genetics
Todd, John A JA; Walker, Neil M NM; Cooper, Jason D JD; Smyth, Deborah J DJ; Downes, Kate K; Plagnol, Vincent V; Bailey, Rebecca R; Nejentsev, Sergey S; Field, Sarah F SF; Payne, Felicity F; Lowe, Christopher E CE; Szeszko, Jeffrey S JS; Hafler, Jason P JP; Zeitels, Lauren L; Yang, Jennie H M JH; Vella, Adrian A; Nutland, Sarah S; Stevens, Helen E HE; Schuilenburg, Helen H; Coleman, Gillian G; Maisuria, Meeta M; Meadows, William W; Smink, Luc J LJ; Healy, Barry B; Burren, Oliver S OS; Lam, Alex A C AA; Ovington, Nigel R NR; Allen, James J; Adlem, Ellen E; Leung, Hin-Tak HT; Wallace, Chris C; Howson, Joanna M M JM; Guja, Cristian C; Ionescu-Tîrgovişte, Constantin C; , ; Simmonds, Matthew J MJ; Heward, Joanne M JM; Gough, Stephen C L SC; , ; Dunger, David B DB; Wicker, Linda S LS; Clayton, David G DG