Polygenic risk scores predict diabetes complications and their response to intensive blood pressure and glucose control.
Diabetologia
Tremblay, Johanne J; Haloui, Mounsif M; Attaoua, Redha R; Tahir, Ramzan R; Hishmih, Camil C; Harvey, François F; Marois-Blanchet, François-Christophe FC; Long, Carole C; Simon, Paul P; Santucci, Lara L; Hizel, Candan C; Chalmers, John J; Marre, Michel M; Harrap, Stephen S; Cífková, Renata R; Krajčoviechová, Alena A; Matthews, David R DR; Williams, Bryan B; Poulter, Neil N; Zoungas, Sophia S; Colagiuri, Stephen S; Mancia, Giuseppe G; Grobbee, Diederick E DE; Rodgers, Anthony A; Liu, Liusheng L; Agbessi, Mawussé M; Bruat, Vanessa V; Favé, Marie-Julie MJ; Harwood, Michelle P MP; Awadalla, Philip P; Woodward, Mark M; Hussin, Julie G JG; Hamet, Pavel P
Clustering of known low and moderate risk alleles rather than a novel recessive high-risk gene in non-BRCA1/2 sib trios affected with breast cancer.
International Journal Of Cancer
Hilbers, Florentine S FS; van 't Hof, Peter J PJ; Meijers, Caro M CM; Mei, Hailiang H; Michailidou, Kyriaki K; Dennis, Joe J; Hogervorst, Frans B L FBL; Nederlof, Petra M PM; van Asperen, Christi J CJ; Devilee, Peter P
A Polygenic Risk Score for Breast Cancer in US Latinas and Latin American Women.
Journal Of The National Cancer Institute
Shieh, Yiwey Y; Fejerman, Laura L; Lott, Paul C PC; Marker, Katie K; Sawyer, Sarah D SD; Hu, Donglei D; Huntsman, Scott S; Torres, Javier J; Echeverry, Magdalena M; Bohórquez, Mabel E ME; Martínez-Chéquer, Juan Carlos JC; Polanco-Echeverry, Guadalupe G; Estrada-Flórez, Ana P AP; , ; Haiman, Christopher A CA; John, Esther M EM; Kushi, Lawrence H LH; Torres-Mejía, Gabriela G; Vidaurre, Tatianna T; Weitzel, Jeffrey N JN; Zambrano, Sandro Casavilca SC; Carvajal-Carmona, Luis G LG; Ziv, Elad E; Neuhausen, Susan L SL
A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer.
Nature Genetics
Wu, Lang L; Shi, Wei W; Long, Jirong J; Guo, Xingyi X; Michailidou, Kyriaki K; Beesley, Jonathan J; Bolla, Manjeet K MK; Shu, Xiao-Ou XO; Lu, Yingchang Y; Cai, Qiuyin Q; Al-Ejeh, Fares F; Rozali, Esdy E; Wang, Qin Q; Dennis, Joe J; Li, Bingshan B; Zeng, Chenjie C; Feng, Helian H; Gusev, Alexander A; Barfield, Richard T RT; Andrulis, Irene L IL; Anton-Culver, Hoda H; Arndt, Volker V; Aronson, Kristan J KJ; Auer, Paul L PL; Barrdahl, Myrto M; Baynes, Caroline C; Beckmann, Matthias W MW; Benitez, Javier J; Bermisheva, Marina M; Blomqvist, Carl C; Bogdanova, Natalia V NV; Bojesen, Stig E SE; Brauch, Hiltrud H; Brenner, Hermann H; Brinton, Louise L; Broberg, Per P; Brucker, Sara Y SY; Burwinkel, Barbara B; Caldés, Trinidad T; Canzian, Federico F; Carter, Brian D BD; Castelao, J Esteban JE; Chang-Claude, Jenny J; Chen, Xiaoqing X; Cheng, Ting-Yuan David TD; Christiansen, Hans H; Clarke, Christine L CL; , ; Collée, Margriet M; Cornelissen, Sten S; Couch, Fergus J FJ; Cox, David D; Cox, Angela A; Cross, Simon S SS; Cunningham, Julie M JM; Czene, Kamila K; Daly, Mary B MB; Devilee, Peter P; Doheny, Kimberly F KF; Dörk, Thilo T; Dos-Santos-Silva, Isabel I; Dumont, Martine M; Dwek, Miriam M; Eccles, Diana M DM; Eilber, Ursula U; Eliassen, A Heather AH; Engel, Christoph C; Eriksson, Mikael M; Fachal, Laura L; Fasching, Peter A PA; Figueroa, Jonine J; Flesch-Janys, Dieter D; Fletcher, Olivia O; Flyger, Henrik H; Fritschi, Lin L; Gabrielson, Marike M; Gago-Dominguez, Manuela M; Gapstur, Susan M SM; García-Closas, Montserrat M; Gaudet, Mia M MM; Ghoussaini, Maya M; Giles, Graham G GG; Goldberg, Mark S MS; Goldgar, David E DE; González-Neira, Anna A; Guénel, Pascal P; Hahnen, Eric E; Haiman, Christopher A CA; Håkansson, Niclas N; Hall, Per P; Hallberg, Emily E; Hamann, Ute U; Harrington, Patricia P; Hein, Alexander A; Hicks, Belynda B; Hillemanns, Peter P; Hollestelle, Antoinette A; Hoover, Robert N RN; Hopper, John L JL; Huang, Guanmengqian G; Humphreys, Keith K; Hunter, David J DJ; Jakubowska, Anna A; Janni, Wolfgang W; John, Esther M EM; Johnson, Nichola N; Jones, Kristine K; Jones, Michael E ME; Jung, Audrey A; Kaaks, Rudolf R; Kerin, Michael J MJ; Khusnutdinova, Elza E; Kosma, Veli-Matti VM; Kristensen, Vessela N VN; Lambrechts, Diether D; Le Marchand, Loic L; Li, Jingmei J; Lindström, Sara S; Lissowska, Jolanta J; Lo, Wing-Yee WY; Loibl, Sibylle S; Lubinski, Jan J; Luccarini, Craig C; Lux, Michael P MP; MacInnis, Robert J RJ; Maishman, Tom T; Kostovska, Ivana Maleva IM; Mannermaa, Arto A; Manson, JoAnn E JE; Margolin, Sara S; Mavroudis, Dimitrios D; Meijers-Heijboer, Hanne H; Meindl, Alfons A; Menon, Usha U; Meyer, Jeffery J; Mulligan, Anna Marie AM; Neuhausen, Susan L SL; Nevanlinna, Heli H; Neven, Patrick P; Nielsen, Sune F SF; Nordestgaard, Børge G BG; Olopade, Olufunmilayo I OI; Olson, Janet E JE; Olsson, Håkan H; Peterlongo, Paolo P; Peto, Julian J; Plaseska-Karanfilska, Dijana D; Prentice, Ross R; Presneau, Nadege N; Pylkäs, Katri K; Rack, Brigitte B; Radice, Paolo P; Rahman, Nazneen N; Rennert, Gad G; Rennert, Hedy S HS; Rhenius, Valerie V; Romero, Atocha A; Romm, Jane J; Rudolph, Anja A; Saloustros, Emmanouil E; Sandler, Dale P DP; Sawyer, Elinor J EJ; Schmidt, Marjanka K MK; Schmutzler, Rita K RK; Schneeweiss, Andreas A; Scott, Rodney J RJ; Scott, Christopher G CG; Seal, Sheila S; Shah, Mitul M; Shrubsole, Martha J MJ; Smeets, Ann A; Southey, Melissa C MC; Spinelli, John J JJ; Stone, Jennifer J; Surowy, Harald H; Swerdlow, Anthony J AJ; Tamimi, Rulla M RM; Tapper, William W; Taylor, Jack A JA; Terry, Mary Beth MB; Tessier, Daniel C DC; Thomas, Abigail A; Thöne, Kathrin K; Tollenaar, Rob A E M RAEM; Torres, Diana D; Truong, Thérèse T; Untch, Michael M; Vachon, Celine C; Van Den Berg, David D; Vincent, Daniel D; Waisfisz, Quinten Q; Weinberg, Clarice R CR; Wendt, Camilla C; Whittemore, Alice S AS; Wildiers, Hans H; Willett, Walter C WC; Winqvist, Robert R; Wolk, Alicja A; Xia, Lucy L; Yang, Xiaohong R XR; Ziogas, Argyrios A; Ziv, Elad E; , ; Dunning, Alison M AM; Pharoah, Paul D P PDP; Simard, Jacques J; Milne, Roger L RL; Edwards, Stacey L SL; Kraft, Peter P; Easton, Douglas F DF; Chenevix-Trench, Georgia G; Zheng, Wei W
Risk, Prediction and Prevention of Hereditary Breast Cancer - Large-Scale Genomic Studies in Times of Big and Smart Data.
Geburtshilfe Und Frauenheilkunde
Wunderle, Marius M; Olmes, Gregor G; Nabieva, Naiba N; Häberle, Lothar L; Jud, Sebastian M SM; Hein, Alexander A; Rauh, Claudia C; Hack, Carolin C CC; Erber, Ramona R; Ekici, Arif B AB; Hoyer, Juliane J; Vasileiou, Georgia G; Kraus, Cornelia C; Reis, André A; Hartmann, Arndt A; Schulz-Wendtland, Rüdiger R; Lux, Michael P MP; Beckmann, Matthias W MW; Fasching, Peter A PA
Common Genetic Variation and Breast Cancer Risk-Past, Present, and Future.
Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Association analysis identifies 65 new breast cancer risk loci.
Nature
Michailidou, Kyriaki K; Lindström, Sara S; Dennis, Joe J; Beesley, Jonathan J; Hui, Shirley S; Kar, Siddhartha S; Lemaçon, Audrey A; Soucy, Penny P; Glubb, Dylan D; Rostamianfar, Asha A; Bolla, Manjeet K MK; Wang, Qin Q; Tyrer, Jonathan J; Dicks, Ed E; Lee, Andrew A; Wang, Zhaoming Z; Allen, Jamie J; Keeman, Renske R; Eilber, Ursula U; French, Juliet D JD; Qing Chen, Xiao X; Fachal, Laura L; McCue, Karen K; McCart Reed, Amy E AE; Ghoussaini, Maya M; Carroll, Jason S JS; Jiang, Xia X; Finucane, Hilary H; Adams, Marcia M; Adank, Muriel A MA; Ahsan, Habibul H; Aittomäki, Kristiina K; Anton-Culver, Hoda H; Antonenkova, Natalia N NN; Arndt, Volker V; Aronson, Kristan J KJ; Arun, Banu B; Auer, Paul L PL; Bacot, François F; Barrdahl, Myrto M; Baynes, Caroline C; Beckmann, Matthias W MW; Behrens, Sabine S; Benitez, Javier J; Bermisheva, Marina M; Bernstein, Leslie L; Blomqvist, Carl C; Bogdanova, Natalia V NV; Bojesen, Stig E SE; Bonanni, Bernardo B; Børresen-Dale, Anne-Lise AL; Brand, Judith S JS; Brauch, Hiltrud H; Brennan, Paul P; Brenner, Hermann H; Brinton, Louise L; Broberg, Per P; Brock, Ian W IW; Broeks, Annegien A; Brooks-Wilson, Angela A; Brucker, Sara Y SY; Brüning, Thomas T; Burwinkel, Barbara B; Butterbach, Katja K; Cai, Qiuyin Q; Cai, Hui H; Caldés, Trinidad T; Canzian, Federico F; Carracedo, Angel A; Carter, Brian D BD; Castelao, Jose E JE; Chan, Tsun L TL; David Cheng, Ting-Yuan TY; Seng Chia, Kee K; Choi, Ji-Yeob JY; Christiansen, Hans H; Clarke, Christine L CL; , ; Collée, Margriet M; Conroy, Don M DM; Cordina-Duverger, Emilie E; Cornelissen, Sten S; Cox, David G DG; Cox, Angela A; Cross, Simon S SS; Cunningham, Julie M JM; Czene, Kamila K; Daly, Mary B MB; Devilee, Peter P; Doheny, Kimberly F KF; Dörk, Thilo T; Dos-Santos-Silva, Isabel I; Dumont, Martine M; Durcan, Lorraine L; Dwek, Miriam M; Eccles, Diana M DM; Ekici, Arif B AB; Eliassen, A Heather AH; Ellberg, Carolina C; Elvira, Mingajeva M; Engel, Christoph C; Eriksson, Mikael M; Fasching, Peter A PA; Figueroa, Jonine J; Flesch-Janys, Dieter D; Fletcher, Olivia O; Flyger, Henrik H; Fritschi, Lin L; Gaborieau, Valerie V; Gabrielson, Marike M; Gago-Dominguez, Manuela M; Gao, Yu-Tang YT; Gapstur, Susan M SM; García-Sáenz, José A JA; Gaudet, Mia M MM; Georgoulias, Vassilios V; Giles, Graham G GG; Glendon, Gord G; Goldberg, Mark S MS; Goldgar, David E DE; González-Neira, Anna A; Grenaker Alnæs, Grethe I GI; Grip, Mervi M; Gronwald, Jacek J; Grundy, Anne A; Guénel, Pascal P; Haeberle, Lothar L; Hahnen, Eric E; Haiman, Christopher A CA; Håkansson, Niclas N; Hamann, Ute U; Hamel, Nathalie N; Hankinson, Susan S; Harrington, Patricia P; Hart, Steven N SN; Hartikainen, Jaana M JM; Hartman, Mikael M; Hein, Alexander A; Heyworth, Jane J; Hicks, Belynda B; Hillemanns, Peter P; Ho, Dona N DN; Hollestelle, Antoinette A; Hooning, Maartje J MJ; Hoover, Robert N RN; Hopper, John L JL; Hou, Ming-Feng MF; Hsiung, Chia-Ni CN; Huang, Guanmengqian G; Humphreys, Keith K; Ishiguro, Junko J; Ito, Hidemi H; Iwasaki, Motoki M; Iwata, Hiroji H; Jakubowska, Anna A; Janni, Wolfgang W; John, Esther M EM; Johnson, Nichola N; Jones, Kristine K; Jones, Michael M; Jukkola-Vuorinen, Arja A; Kaaks, Rudolf R; Kabisch, Maria M; Kaczmarek, Katarzyna K; Kang, Daehee D; Kasuga, Yoshio Y; Kerin, Michael J MJ; Khan, Sofia S; Khusnutdinova, Elza E; Kiiski, Johanna I JI; Kim, Sung-Won SW; Knight, Julia A JA; Kosma, Veli-Matti VM; Kristensen, Vessela N VN; Krüger, Ute U; Kwong, Ava A; Lambrechts, Diether D; Le Marchand, Loic L; Lee, Eunjung E; Lee, Min Hyuk MH; Lee, Jong Won JW; Neng Lee, Chuen C; Lejbkowicz, Flavio F; Li, Jingmei J; Lilyquist, Jenna J; Lindblom, Annika A; Lissowska, Jolanta J; Lo, Wing-Yee WY; Loibl, Sibylle S; Long, Jirong J; Lophatananon, Artitaya A; Lubinski, Jan J; Luccarini, Craig C; Lux, Michael P MP; Ma, Edmond S K ESK; MacInnis, Robert J RJ; Maishman, Tom T; Makalic, Enes E; Malone, Kathleen E KE; Kostovska, Ivana Maleva IM; Mannermaa, Arto A; Manoukian, Siranoush S; Manson, JoAnn E JE; Margolin, Sara S; Mariapun, Shivaani S; Martinez, Maria Elena ME; Matsuo, Keitaro K; Mavroudis, Dimitrios D; McKay, James J; McLean, Catriona C; Meijers-Heijboer, Hanne H; Meindl, Alfons A; Menéndez, Primitiva P; Menon, Usha U; Meyer, Jeffery J; Miao, Hui H; Miller, Nicola N; Taib, Nur Aishah Mohd NAM; Muir, Kenneth K; Mulligan, Anna Marie AM; Mulot, Claire C; Neuhausen, Susan L SL; Nevanlinna, Heli H; Neven, Patrick P; Nielsen, Sune F SF; Noh, Dong-Young DY; Nordestgaard, Børge G BG; Norman, Aaron A; Olopade, Olufunmilayo I OI; Olson, Janet E JE; Olsson, Håkan H; Olswold, Curtis C; Orr, Nick N; Pankratz, V Shane VS; Park, Sue K SK; Park-Simon, Tjoung-Won TW; Lloyd, Rachel R; Perez, Jose I A JIA; Peterlongo, Paolo P; Peto, Julian J; Phillips, Kelly-Anne KA; Pinchev, Mila M; Plaseska-Karanfilska, Dijana D; Prentice, Ross R; Presneau, Nadege N; Prokofyeva, Darya D; Pugh, Elizabeth E; Pylkäs, Katri K; Rack, Brigitte B; Radice, Paolo P; Rahman, Nazneen N; Rennert, Gadi G; Rennert, Hedy S HS; Rhenius, Valerie V; Romero, Atocha A; Romm, Jane J; Ruddy, Kathryn J KJ; Rüdiger, Thomas T; Rudolph, Anja A; Ruebner, Matthias M; Rutgers, Emiel J T EJT; Saloustros, Emmanouil E; Sandler, Dale P DP; Sangrajrang, Suleeporn S; Sawyer, Elinor J EJ; Schmidt, Daniel F DF; Schmutzler, Rita K RK; Schneeweiss, Andreas A; Schoemaker, Minouk J MJ; Schumacher, Fredrick F; Schürmann, Peter P; Scott, Rodney J RJ; Scott, Christopher C; Seal, Sheila S; Seynaeve, Caroline C; Shah, Mitul M; Sharma, Priyanka P; Shen, Chen-Yang CY; Sheng, Grace G; Sherman, Mark E ME; Shrubsole, Martha J MJ; Shu, Xiao-Ou XO; Smeets, Ann A; Sohn, Christof C; Southey, Melissa C MC; Spinelli, John J JJ; Stegmaier, Christa C; Stewart-Brown, Sarah S; Stone, Jennifer J; Stram, Daniel O DO; Surowy, Harald H; Swerdlow, Anthony A; Tamimi, Rulla R; Taylor, Jack A JA; Tengström, Maria M; Teo, Soo H SH; Beth Terry, Mary M; Tessier, Daniel C DC; Thanasitthichai, Somchai S; Thöne, Kathrin K; Tollenaar, Rob A E M RAEM; Tomlinson, Ian I; Tong, Ling L; Torres, Diana D; Truong, Thérèse T; Tseng, Chiu-Chen CC; Tsugane, Shoichiro S; Ulmer, Hans-Ulrich HU; Ursin, Giske G; Untch, Michael M; Vachon, Celine C; van Asperen, Christi J CJ; Van Den Berg, David D; van den Ouweland, Ans M W AMW; van der Kolk, Lizet L; van der Luijt, Rob B RB; Vincent, Daniel D; Vollenweider, Jason J; Waisfisz, Quinten Q; Wang-Gohrke, Shan S; Weinberg, Clarice R CR; Wendt, Camilla C; Whittemore, Alice S AS; Wildiers, Hans H; Willett, Walter W; Winqvist, Robert R; Wolk, Alicja A; Wu, Anna H AH; Xia, Lucy L; Yamaji, Taiki T; Yang, Xiaohong R XR; Har Yip, Cheng C; Yoo, Keun-Young KY; Yu, Jyh-Cherng JC; Zheng, Wei W; Zheng, Ying Y; Zhu, Bin B; Ziogas, Argyrios A; Ziv, Elad E; , ; , ; Lakhani, Sunil R SR; Antoniou, Antonis C AC; Droit, Arnaud A; Andrulis, Irene L IL; Amos, Christopher I CI; Couch, Fergus J FJ; Pharoah, Paul D P PDP; Chang-Claude, Jenny J; Hall, Per P; Hunter, David J DJ; Milne, Roger L RL; García-Closas, Montserrat M; Schmidt, Marjanka K MK; Chanock, Stephen J SJ; Dunning, Alison M AM; Edwards, Stacey L SL; Bader, Gary D GD; Chenevix-Trench, Georgia G; Simard, Jacques J; Kraft, Peter P; Easton, Douglas F DF
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.
Nature Genetics
Warren, Helen R HR; Evangelou, Evangelos E; Cabrera, Claudia P CP; Gao, He H; Ren, Meixia M; Mifsud, Borbala B; Ntalla, Ioanna I; Surendran, Praveen P; Liu, Chunyu C; Cook, James P JP; Kraja, Aldi T AT; Drenos, Fotios F; Loh, Marie M; Verweij, Niek N; Marten, Jonathan J; Karaman, Ibrahim I; Lepe, Marcelo P Segura MP; O'Reilly, Paul F PF; Knight, Joanne J; Snieder, Harold H; Kato, Norihiro N; He, Jiang J; Tai, E Shyong ES; Said, M Abdullah MA; Porteous, David D; Alver, Maris M; Poulter, Neil N; Farrall, Martin M; Gansevoort, Ron T RT; Padmanabhan, Sandosh S; Mägi, Reedik R; Stanton, Alice A; Connell, John J; Bakker, Stephan J L SJ; Metspalu, Andres A; Shields, Denis C DC; Thom, Simon S; Brown, Morris M; Sever, Peter P; Esko, Tõnu T; Hayward, Caroline C; van der Harst, Pim P; Saleheen, Danish D; Chowdhury, Rajiv R; Chambers, John C JC; Chasman, Daniel I DI; Chakravarti, Aravinda A; Newton-Cheh, Christopher C; Lindgren, Cecilia M CM; Levy, Daniel D; Kooner, Jaspal S JS; Keavney, Bernard B; Tomaszewski, Maciej M; Samani, Nilesh J NJ; Howson, Joanna M M JM; Tobin, Martin D MD; Munroe, Patricia B PB; Ehret, Georg B GB; Wain, Louise V LV; , ; , ; , ; , ; , ; , ; , ; , ; , ; , ; ,