Publications:

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Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

Translational And Clinical Pharmacology

Kim, Byungwook B; Yoon, Deok Yong DY; Lee, SeungHwan S; Jang, In-Jin IJ; Yu, Kyung-Sang KS; Cho, Joo-Youn JY; Oh, Jaeseong J

Publication Date: 2021-09

Variant appearance in text: CYP2D6: G42R; rs5030862

PubMed Link: 34621706

Variant Present in the following documents:

• Main text
• tcp-29-135-s001.xls, sheet 1
• tcp-29-135.pdf

View BVdb publication page

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Precision Medicine into Clinical Practice: A Web-Based Tool Enables Real-Time Pharmacogenetic Assessment of Tailored Treatments in Psychiatric Disorders.

Journal Of Personalized Medicine

Zampatti, Stefania S; Fabrizio, Carlo C; Ragazzo, Michele M; Campoli, Giulia G; Caputo, Valerio V; Strafella, Claudia C; Pellicano, Clelia C; Cascella, Raffaella R; Spalletta, Gianfranco G; Petrosini, Laura L; Caltagirone, Carlo C; Termine, Andrea A; Giardina, Emiliano E

Publication Date: 2021-08-27

Variant appearance in text: CYP2D6: 124G>A; Gly42Arg; rs5030862

PubMed Link: 34575628

Variant Present in the following documents:

• Main text
• jpm-11-00851.pdf

View BVdb publication page

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Development and Analytical Validation of a 29 Gene Clinical Pharmacogenetic Genotyping Panel: Multi-Ethnic Allele and Copy Number Variant Detection.

Clinical And Translational Science

Scott, Stuart A SA; Scott, Erick R ER; Seki, Yoshinori Y; Chen, Annette J AJ; Wallsten, Richard R; Owusu Obeng, Aniwaa A; Botton, Mariana R MR; Cody, Neal N; Shi, Huanzhi H; Zhao, Geping G; Brake, Paul P; Nicoletti, Paola P; Yang, Yao Y; Delio, Maria M; Shi, Lisong L; Kornreich, Ruth R; Schadt, Eric E EE; Edelmann, Lisa L

Publication Date: 2021-01

Variant appearance in text: CYP2D6: 124G>A; Gly42Arg; rs5030862

PubMed Link: 32931151

Variant Present in the following documents:

• CTS-14-204-s001.xlsx, sheet 7
• CTS-14-204-s001.xlsx, sheet 1

View BVdb publication page

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Population Pharmacokinetic and Pharmacogenetic Analysis of Mitotane in Patients with Adrenocortical Carcinoma: Towards Individualized Dosing.

Clinical Pharmacokinetics

Yin, Anyue A; Ettaieb, Madeleine H T MHT; Swen, Jesse J JJ; van Deun, Liselotte L; Kerkhofs, Thomas M A TMA; van der Straaten, Robert J H M RJHM; Corssmit, Eleonora P M EPM; Gelderblom, Hans H; Kerstens, Michiel N MN; Feelders, Richard A RA; Eekhoff, Marelise M; Timmers, Henri J L M HJLM; D'Avolio, Antonio A; Cusato, Jessica J; Guchelaar, Henk-Jan HJ; Haak, Harm R HR; Moes, Dirk Jan A R DJAR

Publication Date: 2021-01

Variant appearance in text: CYP2D6: G42R; rs5030862

PubMed Link: 32607875

Variant Present in the following documents:

• 40262_2020_913_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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The Metabolization Profile of the CYP2D6 Gene in Amerindian Populations: A Review.

Genes

Leitão, Luciana P C LPC; Souza, Tatiane P TP; Rodrigues, Juliana C G JCG; Fernandes, Marianne R MR; Santos, Sidney S; Santos, Ney P C NPC

Publication Date: 2020-02-28

Variant appearance in text: CYP2D6: G42R; rs5030862

PubMed Link: 32121156

Variant Present in the following documents:

• Main text
• genes-11-00262.pdf

View BVdb publication page

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A functional polymorphism in the ATP-Binding Cassette B1 transporter predicts pharmacologic response to combination of nortriptyline and morphine in neuropathic pain patients.

Pain

Benavides, Rodrigo R; Vsevolozhskaya, Olga O; Cattaneo, Stefano S; Zaykin, Dmitri D; Brenton, Ashley A; Parisien, Marc M; Verma, Vivek V; Khoury, Samar S; Gilron, Ian I; Diatchenko, Luda L

Publication Date: 2020-03

Variant appearance in text: CYP2D6: G42R; rs5030862

PubMed Link: 31738228

Variant Present in the following documents:

• Main text

View BVdb publication page

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Feasibility of Integrating Panel-Based Pharmacogenomics Testing for Chemotherapy and Supportive Care in Patients With Colorectal Cancer.

Technology In Cancer Research & Treatment

Kasi, Pashtoon Murtaza PM; Koep, Tyler T; Schnettler, Erica E; Shahjehan, Faisal F; Kamatham, Vaishnavi V; Baldeo, Candice C; Hughes, Caren L CL

Publication Date: 2019-01-01

Variant appearance in text: CYP2D6: 124G>A; rs5030862

PubMed Link: 31533552

Variant Present in the following documents:

• OneOme_sample_comprehensive_report.pdf

View BVdb publication page

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Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.

Clinical Pharmacology And Therapeutics

Zhou, Y Y; Ingelman-Sundberg, M M; Lauschke, V M VM

Publication Date: 2017-10

Variant appearance in text: CYP2D6: G42R; rs5030862

PubMed Link: 28378927

Variant Present in the following documents:

• Main text
• CPT-102-688.pdf

View BVdb publication page

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Characterization of ADME gene variation in 21 populations by exome sequencing.

Pharmacogenetics And Genomics

Hovelson, Daniel H DH; Xue, Zhengyu Z; Zawistowski, Matthew M; Ehm, Margaret G MG; Harris, Elizabeth C EC; Stocker, Sophie L SL; Gross, Annette S AS; Jang, In-Jin IJ; Ieiri, Ichiro I; Lee, Jong-Eun JE; Cardon, Lon R LR; Chissoe, Stephanie L SL; Abecasis, Gonçalo G; Nelson, Matthew R MR

Publication Date: 2017-03

Variant appearance in text: CYP2D6: G42R; rs5030862

PubMed Link: 27984508

Variant Present in the following documents:

• fpc-27-089-s005.xlsx, sheet 2

View BVdb publication page

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Assessing the capability of massively parallel sequencing for opportunistic pharmacogenetic screening.

Genetics In Medicine : Official Journal Of The American College Of Medical Genetics

Ng, David D; Hong, Celine S CS; Singh, Larry N LN; Johnston, Jennifer J JJ; Mullikin, James C JC; Biesecker, Leslie G LG

Publication Date: 2017-03

Variant appearance in text: CYP2D6: 124G>A; Gly42Arg

PubMed Link: 27537706

Variant Present in the following documents:

• NIHMS802548-supplement-Table_S4.pdf

View BVdb publication page

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A Landscape of Pharmacogenomic Interactions in Cancer.

Cell

Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ

Publication Date: 2016-07-28

Variant appearance in text: CYP2D6: 124G>A; G42R

PubMed Link: 27397505

Variant Present in the following documents:

• mmc3.xlsx, sheet 3
• mmc3.xlsx, sheet 2

View BVdb publication page

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Multiplex SNaPshot-a new simple and efficient CYP2D6 and ADRB1 genotyping method.

Human Genomics

Ben, Songtao S; Cooper-DeHoff, Rhonda M RM; Flaten, Hanna K HK; Evero, Oghenero O; Ferrara, Tracey M TM; Spritz, Richard A RA; Monte, Andrew A AA

Publication Date: 2016-04-23

Variant appearance in text: CYP2D6: Gly42Arg; rs5030862

PubMed Link: 27108086

Variant Present in the following documents:

• Main text
• 40246_2016_Article_73.pdf

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GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics

Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J

Publication Date: 2015-07-25

Variant appearance in text: CYP2D6: G42R

PubMed Link: 26206375

Variant Present in the following documents:

• 12859_2015_673_MOESM1_ESM.xls, sheet 4

View BVdb publication page

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Protein domain-level landscape of cancer-type-specific somatic mutations.

Plos Computational Biology

Yang, Fan F; Petsalaki, Evangelia E; Rolland, Thomas T; Hill, David E DE; Vidal, Marc M; Roth, Frederick P FP

Publication Date: 2015-03

Variant appearance in text: CYP2D6: G42R

PubMed Link: 25794154

Variant Present in the following documents:

• pcbi.1004147.s001.xlsx, sheet 1

View BVdb publication page

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The relative timing of mutations in a breast cancer genome.

Plos One

Newman, Scott S; Howarth, Karen D KD; Greenman, Chris D CD; Bignell, Graham R GR; Tavaré, Simon S; Edwards, Paul A W PA

Publication Date: 2013

Variant appearance in text: CYP2D6: G42R

PubMed Link: 23762276

Variant Present in the following documents:

• pone.0064991.s002.xls, sheet 7

View BVdb publication page

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Length of psychiatric hospitalization is correlated with CYP2D6 functional status in inpatients with major depressive disorder.

Biomarkers In Medicine

Ruaño, Gualberto G; Szarek, Bonnie L BL; Villagra, David D; Gorowski, Krystyna K; Kocherla, Mohan M; Seip, Richard L RL; Goethe, John W JW; Schwartz, Harold I HI

Publication Date: 2013-06

Variant appearance in text: CYP2D6: G42R

PubMed Link: 23734807

Variant Present in the following documents:

• Main text

View BVdb publication page

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Glutathione metabolism and Parkinson's disease.

Free Radical Biology & Medicine

Smeyne, Michelle M; Smeyne, Richard Jay RJ

Publication Date: 2013-09

Variant appearance in text: CYP2D6: Gly42Arg

PubMed Link: 23665395

Variant Present in the following documents:

• Main text

View BVdb publication page

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Characterization of 107 genomic DNA reference materials for CYP2D6, CYP2C19, CYP2C9, VKORC1, and UGT1A1: a GeT-RM and Association for Molecular Pathology collaborative project.

The Journal Of Molecular Diagnostics : Jmd

Pratt, Victoria M VM; Zehnbauer, Barbara B; Wilson, Jean Amos JA; Baak, Ruth R; Babic, Nikolina N; Bettinotti, Maria M; Buller, Arlene A; Butz, Ken K; Campbell, Matthew M; Civalier, Chris C; El-Badry, Abdalla A; Farkas, Daniel H DH; Lyon, Elaine E; Mandal, Saptarshi S; McKinney, Jason J; Muralidharan, Kasinathan K; Noll, LeAnne L; Sander, Tara T; Shabbeer, Junaid J; Smith, Chingying C; Telatar, Milhan M; Toji, Lorraine L; Vairavan, Anand A; Vance, Carlos C; Weck, Karen E KE; Wu, Alan H B AH; Yeo, Kiang-Teck J KT; Zeller, Markus M; Kalman, Lisa L

Publication Date: 2010-11

Variant appearance in text: CYP2D6: 124G>A

PubMed Link: 20889555

Variant Present in the following documents:

• Main text

View BVdb publication page

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