Publications:

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The complement system in liver diseases: Evidence-based approach and therapeutic options.

Journal Of Translational Autoimmunity

T Lung, B Sakem, L Risch, R Würzner, G Colucci, A Cerny, U Nydegger

Publication Date: 2019-12

Variant appearance in text: PNPLA3: I148M

PMID: 32743505

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The role of omics in the pathophysiology, diagnosis and treatment of non-alcoholic fatty liver disease.

Metabolism: Clinical And Experimental

N Perakakis, K Stefanakis, CS Mantzoros

Publication Date: 2020-07-23

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32712221

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Emerging risk factors for nonalcoholic fatty liver disease associated hepatocellular carcinoma.

Hepatoma Research

JN Benhammou, J Lin, SK Hussain, M El-Kabany

Publication Date: 2020

Variant appearance in text: rs738409

PMID: 32685690

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NAFLD as a continuum: from obesity to metabolic syndrome and diabetes.

Diabetology & Metabolic Syndrome

AF Godoy-Matos, WS Silva Júnior, CM Valerio

Publication Date: 2020

Variant appearance in text: rs738409

PMID: 32684985

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Plasma Lipidome, PNPLA3 polymorphism and hepatic steatosis in hereditary hemochromatosis.

Bmc Gastroenterology

J Seeßle, H Gan-Schreier, M Kirchner, W Stremmel, W Chamulitrat, U Merle

Publication Date: 2020-07-17

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32680469

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Current Trends of Essential Trace Elements in Patients with Chronic Liver Diseases.

Nutrients

T Himoto, T Masaki

Publication Date: 2020-07-14

Variant appearance in text: rs738409

PMID: 32674425

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A Low ω-6 to ω-3 PUFA Ratio (n-6:n-3 PUFA) Diet to Treat Fatty Liver Disease in Obese Youth.

The Journal Of Nutrition

MA Van Name, M Savoye, JM Chick, BT Galuppo, AE Feldstein, B Pierpont, C Johnson, V Shabanova, U Ekong, PL Valentino, G Kim, S Caprio, N Santoro

Publication Date: 2020-07-11

Variant appearance in text: rs738409

PMID: 32652034

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Peroxisome Proliferator-Activated Receptors and Their Novel Ligands as Candidates for the Treatment of Non-Alcoholic Fatty Liver Disease.

Cells

A Fougerat, A Montagner, N Loiseau, H Guillou, W Wahli

Publication Date: 2020-07-08

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32650421

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MBOAT7 down-regulation by genetic and environmental factors predisposes to MAFLD.

Ebiomedicine

M Meroni, M Longo, AL Fracanzani, P Dongiovanni

Publication Date: 2020-07-03

Variant appearance in text: PNPLA3: I148M

PMID: 32629394

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Assessment of Genetic Aspects of Non-alcoholic Fatty Liver and Premature Cardiovascular Events.

Middle East Journal Of Digestive Diseases

S Saki, N Saki, H Poustchi, R Malekzadeh

Publication Date: 2020-04

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32626560

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Highlights From the AASLD/EASL ALD Endpoints Conference 2019.

Clinical Liver Disease

M Bertha, H Maddur

Publication Date: 2020-06

Variant appearance in text: rs738409

PMID: 32617152

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Noninvasive Evaluation of Nonalcoholic Fatty Liver Disease.

Endocrinology And Metabolism (Seoul, Korea)

DH Lee

Publication Date: 2020-06

Variant appearance in text: PNPLA3: 444C>G; I148M; rs738409

PMID: 32615709

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Nonalcoholic fatty liver disease and cardiovascular disease phenotypes.

Sage Open Medicine

G Bisaccia, F Ricci, C Mantini, C Tana, GL Romani, C Schiavone, S Gallina

Publication Date: 2020

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32612827

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Current and Future Treatments in the Fight Against Non-Alcoholic Fatty Liver Disease.

Cancers

B Smeuninx, E Boslem, MA Febbraio

Publication Date: 2020-06-28

Variant appearance in text: rs738409

PMID: 32605253

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Epidemiology: Pathogenesis, and Diagnostic Strategy of Diabetic Liver Disease in Japan.

International Journal Of Molecular Sciences

Y Sumida, T Shima, Y Mitsumoto, T Katayama, A Umemura, K Yamaguchi, Y Itoh, M Yoneda, T Okanoue

Publication Date: 2020-06-18

Variant appearance in text: PNPLA3: I148M

PMID: 32570776

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Effect of gut microbiota and PNPLA3 rs738409 variant on non-alcoholic fatty liver disease (NAFLD) in obese youth.

The Journal Of Clinical Endocrinology And Metabolism

AM Kravetz, T Testerman, B Galuppo, J Graf, B Pierpont, S Siebel, R Feinn, N Santoro

Publication Date: 2020-06-19

Variant appearance in text: rs738409

PMID: 32561908

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Gene polymorphisms of Patatin-like phospholipase domain containing 3 (PNPLA3), adiponectin, leptin in diabetic obese patients.

Plos One

O Aly, HH Zaki, MR Herzalla, A Fathy, N Raafat, MM Hafez

Publication Date: 2020

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32544194

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Nonalcoholic Fatty Liver Disease: An Important Consideration for Primary Care Providers in Hawai'i.

Hawai'I Journal Of Health & Social Welfare

RJ Pattison, JP Esteban, T Sempokuya, J Kewcharoen, S Kalathil, SK Kuwada

Publication Date: 2020-06-01

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32524096

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Association between non-alcoholic fatty liver disease and obstructive sleep apnea.

World Journal Of Gastroenterology

I Umbro, V Fabiani, M Fabiani, F Angelico, M Del Ben

Publication Date: 2020-05-28

Variant appearance in text: PNPLA3: I148M

PMID: 32523319

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Regional difference in the susceptibility of non-alcoholic fatty liver disease in China.

Bmj Open Diabetes Research & Care

M Xia, X Sun, L Zheng, Y Bi, Q Li, L Sun, F Di, H Li, D Zhu, Y Gao, Y Bao, Y Wang, L He, B Wu, S Wang, J Gao, X Gao, H Bian

Publication Date: 2020-06

Variant appearance in text: rs738409

PMID: 32522731

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Combined alcoholic and non-alcoholic steatohepatitis.

Jhep Reports : Innovation In Hepatology

LC Ntandja Wandji, V Gnemmi, P Mathurin, A Louvet

Publication Date: 2020-06

Variant appearance in text: rs738409

PMID: 32514497

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Non-alcoholic fatty liver disease (NAFLD) diagnosis and management-differentiating the essential from the ancillary and the present from the future.

Hepatobiliary Surgery And Nutrition

A Lonardo, S Lugari, F Nascimbeni

Publication Date: 2020-06

Variant appearance in text: PNPLA3: I148M

PMID: 32509834

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PNPLA3 and nonalcoholic fatty liver disease: towards personalized medicine for fatty liver.

Hepatobiliary Surgery And Nutrition

L Yuan, NA Terrrault

Publication Date: 2020-06

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32509828

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Surveillance for Hepatocellular Carcinoma in Patients with Non-Alcoholic Fatty Liver Disease: Universal or Selective?

Cancers

MC Plaz Torres, G Bodini, M Furnari, E Marabotto, P Zentilin, M Strazzabosco, EG Giannini

Publication Date: 2020-05-31

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32486355

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The Role of Insulin Resistance and Diabetes in Nonalcoholic Fatty Liver Disease.

International Journal Of Molecular Sciences

H Fujii, N Kawada, Japan Study Group Of Nafld Jsg-Nafld

Publication Date: 2020-05-29

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32485838

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Medical management of metabolic and cardiovascular complications after liver transplantation.

World Journal Of Gastroenterology

C Becchetti, M Dirchwolf, V Banz, JF Dufour

Publication Date: 2020-05-14

Variant appearance in text: rs738409

PMID: 32476781

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Reduced Lysosomal Acid Lipase Activity in Blood and Platelets Is Associated With Nonalcoholic Fatty Liver Disease.

Clinical And Translational Gastroenterology

F Ferri, M Mischitelli, G Tozzi, E Messina, I Mignini, S Mazzuca, M Pellone, S Parisse, R Marrapodi, M Visentini, F Baratta, M Del Ben, D Pastori, R Perciballi, ML Attilia, M Carbone, A De Santis, F Violi, F Angelico, S Ginanni Corradini

Publication Date: 2020-02

Variant appearance in text: rs738409

PMID: 32463622

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Unique insights from ClinicalTrials.gov by mining protein mutations and RSids in addition to applying the Human Phenotype Ontology.

Plos One

S Alag

Publication Date: 2020

Variant appearance in text: rs738409

PMID: 32459809

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Lack of genetic evidence that fatty liver disease predisposes to COVID-19.

Journal Of Hepatology

L Valenti, O Jamialahmadi, S Romeo

Publication Date: 2020-05-20

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32445883

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Molecular Mechanisms Regulating Obesity-Associated Hepatocellular Carcinoma.

Cancers

Y Rajesh, D Sarkar

Publication Date: 2020-05-20

Variant appearance in text: PNPLA3: Ile148Met; rs738409

PMID: 32443737

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Genetic Susceptibility to Chronic Liver Disease in Individuals from Pakistan.

International Journal Of Molecular Sciences

AM Raja, E Ciociola, IN Ahmad, FS Dar, SMS Naqvi, M Moaeen-Ud-Din, G Kaukab Raja, S Romeo, RM Mancina

Publication Date: 2020-05-18

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32443539

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Non-Alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus: A Position Statement of the Fatty Liver Research Group of the Korean Diabetes Association.

Diabetes & Metabolism Journal

BW Lee, YH Lee, CY Park, EJ Rhee, WY Lee, NH Kim, KM Choi, KG Park, YK Choi, BS Cha, DH Lee,

Publication Date: 2020-05-11

Variant appearance in text: PNPLA3: 444C>G; I148M; rs738409

PMID: 32431115

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Chia (Salvia hispanica)-supplemented diet ameliorates non-alcoholic fatty liver disease and its metabolic abnormalities in humans.

Lipids In Health And Disease

A Medina-Urrutia, AR Lopez-Uribe, M El Hafidi, MDC González-Salazar, R Posadas-Sánchez, E Jorge-Galarza, L Del Valle-Mondragón, JG Juárez-Rojas

Publication Date: 2020-05-19

Variant appearance in text: rs738409

PMID: 32430018

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The Identification of Admixture Patterns Could Refine Pharmacogenetic Counseling: Analysis of a Population-Based Sample in Mexico.

Frontiers In Pharmacology

JJ Martínez-Magaña, AD Genis-Mendoza, JA Villatoro Velázquez, B Camarena, R Martín Del Campo Sanchez, C Fleiz Bautista, M Bustos Gamiño, E Reséndiz, A Aguilar, ME Medina-Mora, H Nicolini

Publication Date: 2020

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32390825

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Review article: the emerging role of genetics in precision medicine for patients with non-alcoholic steatohepatitis.

Alimentary Pharmacology & Therapeutics

B Carlsson, D Lindén, G Brolén, M Liljeblad, M Bjursell, S Romeo, R Loomba

Publication Date: 2020-05-07

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32383295

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Interplay of PNPLA3 and HSD17B13 Variants in Modulating the Risk of Hepatocellular Carcinoma among Hepatitis C Patients.

Gastroenterology Research And Practice

C De Benedittis, M Bellan, M Crevola, E Boin, MN Barbaglia, VR Mallela, P Ravanini, E Ceriani, S Fangazio, PP Sainaghi, ME Burlone, R Minisini, M Pirisi

Publication Date: 2020

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32382265

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Association of the SH2B1 rs7359397 Gene Polymorphism with Steatosis Severity in Subjects with Obesity and Non-Alcoholic Fatty Liver Disease.

Nutrients

N Perez-Diaz-Del-Campo, I Abete, I Cantero, BA Marin-Alejandre, JI Monreal, M Elorz, JI Herrero, A Benito-Boillos, JI Riezu-Boj, FI Milagro, JA Tur, JA Martinez, MA Zulet

Publication Date: 2020-04-29

Variant appearance in text: PNPLA3: I148M

PMID: 32365683

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High Protein Intake Is Associated With Histological Disease Activity in Patients With NAFLD.

Hepatology Communications

S Lang, A Martin, F Farowski, H Wisplinghoff, MJGT Vehreschild, J Liu, M Krawczyk, A Nowag, A Kretzschmar, J Herweg, B Schnabl, XM Tu, F Lammert, T Goeser, F Tacke, K Heinzer, P Kasper, HM Steffen, M Demir

Publication Date: 2020-05

Variant appearance in text: PNPLA3: I148M

PMID: 32363319

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Differential Associations of Circulating MicroRNAs With Pathogenic Factors in NAFLD.

Hepatology Communications

G Ezaz, HD Trivedi, MA Connelly, C Filozof, K Howard, M L Parrish, M Kim, MA Herman, I Nasser, NH Afdhal, ZG Jiang, M Lai

Publication Date: 2020-05

Variant appearance in text: rs738409

PMID: 32363318

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Lysosomal acid lipase is the major acid retinyl ester hydrolase in cultured human hepatic stellate cells but not essential for retinyl ester degradation.

Biochimica Et Biophysica Acta. Molecular And Cell Biology Of Lipids

C Wagner, V Hois, L Pajed, LM Pusch, H Wolinski, M Trauner, R Zimmermann, U Taschler, A Lass

Publication Date: 2020-04-30

Variant appearance in text: PNPLA3: I148M

PMID: 32361002

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Prevalence, clinical characteristics, risk factors, and indicators for lean Chinese adults with nonalcoholic fatty liver disease.

World Journal Of Gastroenterology

J Zeng, RX Yang, C Sun, Q Pan, RN Zhang, GY Chen, Y Hu, JG Fan

Publication Date: 2020-04-21

Variant appearance in text: rs738409

PMID: 32351294

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Possible Relevance of PNPLA3 and TLL1 Gene Polymorphisms to the Efficacy of PEG-IFN Therapy for HBV-Infected Patients.

International Journal Of Molecular Sciences

H Enomoto, N Aizawa, K Hasegawa, N Ikeda, Y Sakai, K Yoh, R Takata, Y Yuri, K Kishino, Y Shimono, N Ishii, T Takashima, T Nishimura, H Nishikawa, Y Iwata, H Iijima, S Nishiguchi

Publication Date: 2020-04-27

Variant appearance in text: rs738409

PMID: 32349377

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Noninvasive Diagnosis of NAFLD and NASH.

Cells

VA Piazzolla, A Mangia

Publication Date: 2020-04-17

Variant appearance in text: rs738409

PMID: 32316690

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Nonalcoholic steatohepatitis Fitness Intervention in Thrombosis (NASHFit): Study protocol for a randomized controlled trial of a supervised aerobic exercise program to reduce elevated clotting risk in patients with NASH.

Contemporary Clinical Trials Communications

JG Stine, I Schreibman, S Navabi, M Kang, J Dahmus, C Soriano, G Rivas, B Hummer, M Beyer, H Tressler, SR Kimball, AD Patterson, K Schmitz, C Sciamanna

Publication Date: 2020-06

Variant appearance in text: rs738409

PMID: 32309672

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Human Liver Spheroids as a Model to Study Aetiology and Treatment of Hepatic Fibrosis.

Cells

T Hurrell, V Kastrinou-Lampou, A Fardellas, DFG Hendriks, Å Nordling, I Johansson, A Baze, C Parmentier, L Richert, M Ingelman-Sundberg

Publication Date: 2020-04-14

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32295224

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The Lipolysome-A Highly Complex and Dynamic Protein Network Orchestrating Cytoplasmic Triacylglycerol Degradation.

Metabolites

P Hofer, U Taschler, R Schreiber, P Kotzbeck, G Schoiswohl

Publication Date: 2020-04-10

Variant appearance in text: PNPLA3: I148M

PMID: 32290093

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A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.

Plos Genetics

CA Emdin, ME Haas, AV Khera, K Aragam, M Chaffin, D Klarin, G Hindy, L Jiang, WQ Wei, Q Feng, J Karjalainen, A Havulinna, T Kiiskinen, A Bick, D Ardissino, JG Wilson, H Schunkert, R McPherson, H Watkins, R Elosua, MJ Bown, NJ Samani, U Baber, J Erdmann, N Gupta, J Danesh, D Saleheen, KM Chang, M Vujkovic, B Voight, S Damrauer, J Lynch, D Kaplan, M Serper, P Tsao, , J Mercader, C Hanis, M Daly, J Denny, S Gabriel, S Kathiresan

Publication Date: 2020-04-13

Variant appearance in text: rs738409

PMID: 32282858

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Non-alcoholic Fatty Liver Disease: Growing Burden, Adverse Outcomes and Associations.

Journal Of Clinical And Translational Hepatology

R Kumar, RN Priyadarshi, U Anand

Publication Date: 2020-03-28

Variant appearance in text: PNPLA3: I148M

PMID: 32274348

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Screening of Novel Pharmacogenetic Candidates for Mercaptopurine-Induced Toxicity in Patients With Acute Lymphoblastic Leukemia.

Frontiers In Pharmacology

M Cao, D Yin, Y Qin, F Liao, Y Su, X Xia, J Gao, Y Zhu, W Zhang, Y Shu, X Lu

Publication Date: 2020

Variant appearance in text: rs738409

PMID: 32265697

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Pathogenesis of Nonalcoholic Steatohepatitis: An Overview.

Hepatology Communications

G Parthasarathy, X Revelo, H Malhi

Publication Date: 2020-04

Variant appearance in text: PNPLA3: I148M

PMID: 32258944

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Inherited iron overload disorders.

Translational Gastroenterology And Hepatology

A Piperno, S Pelucchi, R Mariani

Publication Date: 2020

Variant appearance in text: rs738409

PMID: 32258529

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Importance of genetic polymorphisms in liver transplantation outcomes.

World Journal Of Gastroenterology

T Kelava, P Turcic, A Markotic, A Ostojic, D Sisl, A Mrzljak

Publication Date: 2020-03-28

Variant appearance in text: rs738409

PMID: 32256016

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Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis.

Journal Of Hepatology

CA Parisinos, HR Wilman, EL Thomas, M Kelly, RC Nicholls, J McGonigle, S Neubauer, AD Hingorani, RS Patel, H Hemingway, JD Bell, R Banerjee, H Yaghootkar

Publication Date: 2020-04-02

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32247823

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Prevalence and Risk Factors of Metabolic Associated Fatty Liver Disease in Xinxiang, China.

International Journal Of Environmental Research And Public Health

H Li, M Guo, Z An, J Meng, J Jiang, J Song, W Wu

Publication Date: 2020-03-11

Variant appearance in text: PNPLA3: I148M

PMID: 32168920

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Gene-environment interactions due to quantile-specific heritability of triglyceride and VLDL concentrations.

Scientific Reports

PT Williams

Publication Date: 2020-03-11

Variant appearance in text: rs738409

PMID: 32161301

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Hydroxysteroid 17-β dehydrogenase 13 variant increases phospholipids and protects against fibrosis in nonalcoholic fatty liver disease.

Jci Insight

PK Luukkonen, T Tukiainen, A Juuti, H Sammalkorpi, PAN Haridas, O Niemelä, J Arola, M Orho-Melander, A Hakkarainen, PT Kovanen, O Dwivedi, L Groop, L Hodson, A Gastaldelli, T Hyötyläinen, M Orešič, H Yki-Järvinen

Publication Date: 2020-03-12

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32161197

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Sex Hormone-Binding Globulin Levels Are Inversely Associated With Nonalcoholic Fatty Liver Disease in HIV-Infected and -Uninfected Men.

Open Forum Infectious Diseases

JC Price, R Wang, EC Seaberg, TT Brown, MJ Budoff, LA Kingsley, FJ Palella, MD Witt, WS Post, JE Lake, CL Thio

Publication Date: 2019-12

Variant appearance in text: rs738409

PMID: 32128321

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Limitations of non-invasive tests for assessment of liver fibrosis.

Jhep Reports (Online)

K Patel, G Sebastiani

Publication Date: 2020-04

Variant appearance in text: rs738409

PMID: 32118201

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A Pilot Study Assessing the Possible Combined Effect of Physical Activity and PNPLA3 rs738409 Polymorphism on the Risk for Non-Alcoholic Fatty Liver Disease in the Japanese Elderly General Population.

Diabetes, Metabolic Syndrome And Obesity : Targets And Therapy

N Muto, K Oniki, M Kudo, Y Obata, Y Sakamoto, N Tokumaru, T Izuka, T Watanabe, K Otake, Y Ogata, J Saruwatari

Publication Date: 2020

Variant appearance in text: PNPLA3: 444C>G; I148M; rs738409

PMID: 32104030

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Molecular Mechanisms: Connections between Nonalcoholic Fatty Liver Disease, Steatohepatitis and Hepatocellular Carcinoma.

International Journal Of Molecular Sciences

T Kanda, T Goto, Y Hirotsu, R Masuzaki, M Moriyama, M Omata

Publication Date: 2020-02-23

Variant appearance in text: PNPLA3: 444C>G; I148M; rs738409

PMID: 32102237

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Independent and joint correlation of PNPLA3 I148M and TM6SF2 E167K variants with the risk of coronary heart disease in patients with non-alcoholic fatty liver disease.

Lipids In Health And Disease

JT Wu, SS Liu, XJ Xie, Q Liu, YN Xin, SY Xuan

Publication Date: 2020-02-24

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32093693

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Mboat7 down-regulation by hyper-insulinemia induces fat accumulation in hepatocytes.

Ebiomedicine

M Meroni, P Dongiovanni, M Longo, F Carli, G Baselli, R Rametta, S Pelusi, S Badiali, M Maggioni, M Gaggini, AL Fracanzani, S Romeo, S Gatti, NO Davidson, A Gastaldelli, L Valenti

Publication Date: 2020-02-11

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32058943

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Natural History of Nonalcoholic Fatty Liver Disease: Implications for Clinical Practice and an Individualized Approach.

Canadian Journal Of Gastroenterology & Hepatology

I Grgurevic, K Podrug, I Mikolasevic, M Kukla, A Madir, EA Tsochatzis

Publication Date: 2020

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32051820

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NAFLD Preclinical Models: More than a Handful, Less of a Concern?

Biomedicines

Y Oligschlaeger, R Shiri-Sverdlov

Publication Date: 2020-02-08

Variant appearance in text: PNPLA3: I148M

PMID: 32046285

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The effect of liver enzymes on body composition: A Mendelian randomization study.

Plos One

J Liu, SL Au Yeung, MK Kwok, JYY Leung, LL Hui, GM Leung, CM Schooling

Publication Date: 2020

Variant appearance in text: rs738409

PMID: 32045441

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Metabolic regulation of hepatic PNPLA3 expression and severity of liver fibrosis in patients with NASH.

Liver International : Official Journal Of The International Association For The Study Of The Liver

FV Bruschi, M Tardelli, M Herac, T Claudel, M Trauner

Publication Date: 2020-02-11

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32043752

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Lifestyle modification in NAFLD/NASH: Facts and figures.

Jhep Reports (Online)

K Hallsworth, LA Adams

Publication Date: 2019-12

Variant appearance in text: rs738409

PMID: 32039399

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Serum lipopolysaccharides predict advanced liver disease in the general population.

Jhep Reports (Online)

V Männistö, M Färkkilä, P Pussinen, A Jula, S Männistö, A Lundqvist, L Valsta, V Salomaa, M Perola, F Åberg

Publication Date: 2019-11

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32039385

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Non-alcoholic fatty liver disease in lean individuals.

Jhep Reports (Online)

S Albhaisi, A Chowdhury, AJ Sanyal

Publication Date: 2019-10

Variant appearance in text: rs738409

PMID: 32039383

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Quantitative digital pathology reveals association of cell-specific PNPLA3 transcription with NAFLD disease activity.

Jhep Reports (Online)

B Sandhu, MC Perez Matos, S Tran, A Zhong, E Csizmadia, M Kim, MA Herman, I Nasser, M Lai, ZG Jiang

Publication Date: 2019-09

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 32039370

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Metabolomic and Lipidomic Biomarkers for Premalignant Liver Disease Diagnosis and Therapy.

Metabolites

D Beyoğlu, JR Idle

Publication Date: 2020-01-28

Variant appearance in text: PNPLA3: I148M

PMID: 32012846

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Genetics of Non-Alcoholic Fatty Liver and Cardiovascular Disease: Implications for Therapy?

Frontiers In Pharmacology

K Chandrasekharan, W Alazawi

Publication Date: 2019

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 31969816

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Inflammation and fibrosis in chronic liver diseases including non-alcoholic fatty liver disease and hepatitis C.

World Journal Of Gastroenterology

S Tanwar, F Rhodes, A Srivastava, PM Trembling, WM Rosenberg

Publication Date: 2020-01-14

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 31969775

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Impact of HSD17B13 rs72613567 genotype on hepatic decompensation and mortality in patients with portal hypertension.

Liver International : Official Journal Of The International Association For The Study Of The Liver

B Scheiner, AF Stättermayer, P Schwabl, T Bucsics, R Paternostro, D Bauer, B Simbrunner, R Schmidt, R Marculescu, A Ferlitsch, M Peck-Radosavljevic, M Pinter, M Trauner, T Reiberger, P Ferenci, M Mandorfer

Publication Date: 2020-02

Variant appearance in text: PNPLA3: I148M

PMID: 31967400

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The endothelial function biomarker soluble E-selectin is associated with nonalcoholic fatty liver disease.

Liver International : Official Journal Of The International Association For The Study Of The Liver

N Simons, M Bijnen, KAM Wouters, SS Rensen, JWJ Beulens, MMJ van Greevenbroek, LM 't Hart, JWM Greve, CJH van der Kallen, NC Schaper, CG Schalkwijk, CDA Stehouwer, MCGJ Brouwers

Publication Date: 2020-01-20

Variant appearance in text: rs738409

PMID: 31960587

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The dawn of a new era for nonalcoholic fatty liver disease?

Hepatobiliary Surgery And Nutrition

A Mantovani, C Zusi

Publication Date: 2019-12

Variant appearance in text: rs738409

PMID: 31929991

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Association of rs780094 polymorphism of glucokinase regulatory protein with non-alcoholic fatty liver disease.

Bmc Research Notes

S Mohammadi, S Farajnia, M Shadmand, F Mohseni, R Baghban

Publication Date: 2020-01-10

Variant appearance in text: rs738409

PMID: 31924263

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PNPLA3-A Potential Therapeutic Target for Personalized Treatment of Chronic Liver Disease.

Frontiers In Medicine

XC Dong

Publication Date: 2019

Variant appearance in text: rs738409

PMID: 31921875

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Pathogenesis of Insulin Resistance and Atherogenic Dyslipidemia in Nonalcoholic Fatty Liver Disease.

Journal Of Clinical And Translational Hepatology

DH Akhtar, U Iqbal, LM Vazquez-Montesino, BB Dennis, A Ahmed

Publication Date: 2019-12-28

Variant appearance in text: rs738409

PMID: 31915606

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Association of GCKR Gene Polymorphisms with the Risk of Nonalcoholic Fatty Liver Disease and Coronary Artery Disease in a Chinese Northern Han Population.

Journal Of Clinical And Translational Hepatology

H Gao, S Liu, Z Zhao, X Yu, Q Liu, Y Xin, S Xuan

Publication Date: 2019-12-28

Variant appearance in text: rs738409

PMID: 31915598

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A Microphysiological System for Studying Nonalcoholic Steatohepatitis.

Hepatology Communications

T Kostrzewski, P Maraver, L Ouro-Gnao, A Levi, S Snow, A Miedzik, K Rombouts, D Hughes

Publication Date: 2020-01

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 31909357

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Circulating MicroRNA-122 and Fibrosis Stage Predict Mortality of Japanese Patients With Histopathologically Confirmed NAFLD.

Hepatology Communications

N Akuta, Y Kawamura, Y Arase, S Saitoh, S Fujiyama, H Sezaki, T Hosaka, M Kobayashi, M Kobayashi, Y Suzuki, F Suzuki, K Ikeda, H Kumada

Publication Date: 2020-01

Variant appearance in text: rs738409

PMID: 31909356

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FIB-4 Index and Diabetes Mellitus Are Associated with Chronic Kidney Disease in Japanese Patients with Non-Alcoholic Fatty Liver Disease.

International Journal Of Molecular Sciences

Y Seko, K Yano, A Takahashi, S Okishio, S Kataoka, K Okuda, N Mizuno, M Takemura, H Taketani, A Umemura, T Nishikawa, K Yamaguchi, M Moriguchi, T Okanoue, Y Itoh

Publication Date: 2019-12-25

Variant appearance in text: PNPLA3: I148M; rs738409

PMID: 31881781

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Anti-NASH Drug Development Hitches a Lift on PPAR Agonism.

Cells

J Boeckmans, A Natale, M Rombaut, K Buyl, V Rogiers, J De Kock, T Vanhaecke, R M Rodrigues

Publication Date: 2019-12-21

Variant appearance in text: rs738409

PMID: 31877771

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Metabolic Hallmarks of Hepatic Stellate Cells in Liver Fibrosis.

Cells

O Khomich, AV Ivanov, B Bartosch

Publication Date: 2019-12-20

Variant appearance in text: PNPLA3: I148M

PMID: 31861818

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Nonalcoholic Fatty Liver Disease: A Challenge from Mechanisms to Therapy.

Journal Of Clinical Medicine

G Tarantino, V Citro, D Capone

Publication Date: 2019-12-19

Variant appearance in text: PNPLA3: I148M

PMID: 31861591

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Paraoxonase-1 Serum Concentration and PON1 Gene Polymorphisms: Relationship with Non-Alcoholic Fatty Liver Disease.

Journal Of Clinical Medicine

MV Milaciu, ȘC Vesa, IC Bocșan, L Ciumărnean, D Sâmpelean, V Negrean, RM Pop, DM Matei, S Pașca, AL Răchișan, AD Buzoianu, M Acalovschi

Publication Date: 2019-12-13

Variant appearance in text: rs738409

PMID: 31847187

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Alternative transcript annotations:

Transcript	cDNA	Protein	Consequence	Exon	Intron
ENST00000216180.3	c.444C>G	p.Ile148Met	missense_variant	3/9	-
ENST00000406117.2	c.*76C>G	-	3_prime_UTR_variant,NMD_transcript_variant	3/10	-
ENST00000423180.2	c.432C>G	p.Ile144Met	missense_variant	3/9	-
ENST00000478713.1	n.478C>G	-	non_coding_transcript_exon_variant	3/4	-
NM_025225.3	c.444C>G	p.Ile148Met	missense_variant	3/9	-