Hepatic Steatosis in Infancy: The Beginning of Pediatric Nonalcoholic Fatty Liver Disease?
Jpgn Reports
McNelis, Kera K; Yodoshi, Toshifumi T; Divanovic, Senad S; Gandhi, Chandrashekhar C; Kim, Jae H JH; Anton, Christopher G CG; Trout, Andrew T AT; Mouzaki, Marialena M
An international multidisciplinary consensus statement on MAFLD and the risk of CVD.
Hepatology International
Zhou, Xiao-Dong XD; Targher, Giovanni G; Byrne, Christopher D CD; Somers, Virend V; Kim, Seung Up SU; Chahal, C Anwar A CAA; Wong, Vincent Wai-Sun VW; Cai, Jingjing J; Shapiro, Michael D MD; Eslam, Mohammed M; Steg, Philippe Gabriel PG; Sung, Ki-Chul KC; Misra, Anoop A; Li, Jian-Jun JJ; Brotons, Carlos C; Huang, Yuli Y; Papatheodoridis, George V GV; Sun, Aijun A; Yilmaz, Yusuf Y; Chan, Wah Kheong WK; Huang, Hui H; Méndez-Sánchez, Nahum N; Alqahtani, Saleh A SA; Cortez-Pinto, Helena H; Lip, Gregory Y H GYH; de Knegt, Robert J RJ; Ocama, Ponsiano P; Romero-Gomez, Manuel M; Fudim, Marat M; Sebastiani, Giada G; Son, Jang Won JW; Ryan, John D JD; Ikonomidis, Ignatios I; Treeprasertsuk, Sombat S; Pastori, Daniele D; Lupsor-Platon, Monica M; Tilg, Herbert H; Ghazinyan, Hasmik H; Boursier, Jerome J; Hamaguchi, Masahide M; Nguyen, Mindie H MH; Fan, Jian-Gao JG; Goh, George Boon-Bee GB; Al Mahtab, Mamun M; Hamid, Saeed S; Perera, Nilanka N; George, Jacob J; Zheng, Ming-Hua MH
The rationale and study design of two phase II trials examining the effects of BI 685,509, a soluble guanylyl cyclase activator, on clinically significant portal hypertension in patients with compensated cirrhosis.
Trials
Reiberger, Thomas T; Berzigotti, Annalisa A; Trebicka, Jonel J; Ertle, Judith J; Gashaw, Isabella I; Swallow, Ros R; Tomisser, Andrea A
Integration of deep learning-based histopathology and transcriptomics reveals key genes associated with fibrogenesis in patients with advanced NASH.
Cell Reports. Medicine
Conway, Jake J; Pouryahya, Maryam M; Gindin, Yevgeniy Y; Pan, David Z DZ; Carrasco-Zevallos, Oscar M OM; Mountain, Victoria V; Subramanian, G Mani GM; Montalto, Michael C MC; Resnick, Murray M; Beck, Andrew H AH; Huss, Ryan S RS; Myers, Robert P RP; Taylor-Weiner, Amaro A; Wapinski, Ilan I; Chung, Chuhan C
Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Hepatic stellate cell activation markers are regulated by the vagus nerve in systemic inflammation.
Bioelectronic Medicine
Ahmed, Osman O; Caravaca, April S AS; Crespo, Maria M; Dai, Wanmin W; Liu, Ting T; Guo, Qi Q; Leiva, Magdalena M; Sabio, Guadalupe G; Shavva, Vladimir S VS; Malin, Stephen G SG; Olofsson, Peder S PS
Metabolic-Dysfunction-Associated Fatty Liver Disease and Gut Microbiota: From Fatty Liver to Dysmetabolic Syndrome.
Medicina (Kaunas, Lithuania)
Abenavoli, Ludovico L; Scarlata, Giuseppe Guido Maria GGM; Scarpellini, Emidio E; Boccuto, Luigi L; Spagnuolo, Rocco R; Tilocca, Bruno B; Roncada, Paola P; Luzza, Francesco F
The I148M PNPLA3 variant mitigates niacin beneficial effects: How the genetic screening in non-alcoholic fatty liver disease patients gains value.
Frontiers In Nutrition
Paolini, Erika E; Longo, Miriam M; Meroni, Marica M; Tria, Giada G; Cespiati, Annalisa A; Lombardi, Rosa R; Badiali, Sara S; Maggioni, Marco M; Fracanzani, Anna Ludovica AL; Dongiovanni, Paola P
Publication Date: 2023
Variant appearance in text: PNPLA3: I148M; rs738409
Uncovering the NAFLD burden in people living with HIV from high- and middle-income nations: a meta-analysis with a data gap from Subsaharan Africa.
Journal Of The International Aids Society
Manzano-Nunez, Ramiro R; Rivera-Esteban, Jesús J; Navarro, Jordi J; Bañares, Juan J; Sena, Elena E; Schattenberg, Jörn M JM; Lazarus, Jeffrey V JV; Curran, Adria A; Pericàs, Juan M JM
Patatin-like phospholipase domain-containing 3 gene (PNPLA3) polymorphic (rs738409) single nucleotide polymorphisms and susceptibility to nonalcoholic fatty liver disease: A meta-analysis of twenty studies.
Medicine
Zhao, Yan Y; Zhao, Wenli W; Ma, Jingchao J; Toshiyoshi, Maeda M; Zhao, Ye Y
Publication Date: 2023-03-10
Variant appearance in text: PNPLA3: I148M; rs738409
High producer variant of lipoprotein lipase may protect from hepatocellular carcinoma in alcohol-associated cirrhosis.
Jhep Reports : Innovation In Hepatology
Schmalz, Franziska F; Fischer, Janett J; Innes, Hamish H; Buch, Stephan S; Möller, Christine C; Matz-Soja, Madlen M; von Schönfels, Witigo W; Krämer, Benjamin B; Langhans, Bettina B; Klüners, Alexandra A; Soyka, Michael M; Stickel, Felix F; Nattermann, Jacob J; Strassburg, Christian P CP; Berg, Thomas T; Lutz, Philipp P; Nischalke, Hans Dieter HD
Publication Date: 2023-04
Variant appearance in text: PNPLA3: I148M; rs738409