Association of Inherited Genetic Factors With Drug-Induced Hepatic Damage Among Children With Acute Lymphoblastic Leukemia.
Jama Network Open
Yang, Wenjian W; Karol, Seth E SE; Hoshitsuki, Keito K; Lee, Shawn S; Larsen, Eric C EC; Winick, Naomi N; Carroll, William L WL; Loh, Mignon L ML; Raetz, Elizabeth A EA; Hunger, Stephen P SP; Winter, Stuart S SS; Dunsmore, Kimberly P KP; Devidas, Meenakshi M; Relling, Mary V MV; Yang, Jun J JJ
Fasting glucose mediates the influence of genetic variants of SOD2 gene on lean non-alcoholic fatty liver disease.
Frontiers In Genetics
Wu, Na N; Zhai, Xiangyu X; Yuan, Fan F; Li, Jie J; Yu, Ning N; Zhang, Fengwei F; Li, Dong D; Wang, Jianying J; Zhang, Lei L; Shi, Yi Y; Ji, Guang G; He, Guang G; Liu, Baocheng B
Update on Non-Alcoholic Fatty Liver Disease-Associated Single Nucleotide Polymorphisms and Their Involvement in Liver Steatosis, Inflammation, and Fibrosis: A Narrative Review
Iranian Biomedical Journal
Dwi Astarini, Fajar F; Ratnasari, Neneng N; Wasityastuti, Widya W
Genetic variation in TERT modifies the risk of hepatocellular carcinoma in alcohol-related cirrhosis: results from a genome-wide case-control study.
Gut
Buch, Stephan S; Innes, Hamish H; Lutz, Philipp Ludwig PL; Nischalke, Hans Dieter HD; Marquardt, Jens U JU; Fischer, Janett J; Weiss, Karl Heinz KH; Rosendahl, Jonas J; Marot, Astrid A; Krawczyk, Marcin M; Casper, Markus M; Lammert, Frank F; Eyer, Florian F; Vogel, Arndt A; Marhenke, Silke S; von Felden, Johann J; Sharma, Rohini R; Atkinson, Stephen Rahul SR; McQuillin, Andrew A; Nattermann, Jacob J; Schafmayer, Clemens C; Franke, Andre A; Strassburg, Christian C; Rietschel, Marcella M; Altmann, Heidi H; Sulk, Stefan S; Thangapandi, Veera Raghavan VR; Brosch, Mario M; Lackner, Carolin C; Stauber, Rudolf E RE; Canbay, Ali A; Link, Alexander A; Reiberger, Thomas T; Mandorfer, Mattias M; Semmler, Georg G; Scheiner, Bernhard B; Datz, Christian C; Romeo, Stefano S; Ginanni Corradini, Stefano S; Irving, William Lucien WL; Morling, Joanne R JR; Guha, Indra Neil IN; Barnes, Eleanor E; Ansari, M Azim MA; Quistrebert, Jocelyn J; Valenti, Luca L; Müller, Sascha A SA; Morgan, Marsha Yvonne MY; Dufour, Jean-François JF; Trebicka, Jonel J; Berg, Thomas T; Deltenre, Pierre P; Mueller, Sebastian S; Hampe, Jochen J; Stickel, Felix F
Association of Genetic Risk Score With NAFLD in An Ethnically Diverse Cohort.
Hepatology Communications
Wang, Jun J; Conti, David V DV; Bogumil, David D; Sheng, Xin X; Noureddin, Mazen M; Wilkens, Lynne R LR; Le Marchand, Loic L; Rosen, Hugo R HR; Haiman, Christopher A CA; Setiawan, Veronica Wendy VW
Mitochondrial Mutations and Genetic Factors Determining NAFLD Risk.
International Journal Of Molecular Sciences
Dabravolski, Siarhei A SA; Bezsonov, Evgeny E EE; Baig, Mirza S MS; Popkova, Tatyana V TV; Nedosugova, Ludmila V LV; Starodubova, Antonina V AV; Orekhov, Alexander N AN
Validating a non-invasive, ALT-based non-alcoholic fatty liver phenotype in the million veteran program.
Plos One
Serper, Marina M; Vujkovic, Marijana M; Kaplan, David E DE; Carr, Rotonya M RM; Lee, Kyung Min KM; Shao, Qing Q; Miller, Donald R DR; Reaven, Peter D PD; Phillips, Lawrence S LS; O'Donnell, Christopher J CJ; Meigs, James B JB; Wilson, Peter W F PWF; Vickers-Smith, Rachel R; Kranzler, Henry R HR; Justice, Amy C AC; Gaziano, John M JM; Muralidhar, Sumitra S; Pyarajan, Saiju S; DuVall, Scott L SL; Assimes, Themistocles L TL; Lee, Jennifer S JS; Tsao, Philip S PS; Rader, Daniel J DJ; Damrauer, Scott M SM; Lynch, Julie A JA; Saleheen, Danish D; Voight, Benjamin F BF; Chang, Kyong-Mi KM; ,
Single Nucleotide Polymorphisms in PEMT and MTHFR Genes are Associated with Omega 3 and 6 Fatty Acid Levels in the Red Blood Cells of Children with Obesity.
Nutrients
Serafim, Vlad V; Chirita-Emandi, Adela A; Andreescu, Nicoleta N; Tiugan, Diana-Andreea DA; Tutac, Paul P; Paul, Corina C; Velea, Iulian I; Mihailescu, Alexandra A; Șerban, Costela Lăcrimioara CL; Zimbru, Cristian G CG; Puiu, Maria M; Niculescu, Mihai Dinu MD
Genome-Wide Association Study Identifies Loci for Liver Enzyme Concentrations in Mexican Americans: The GUARDIAN Consortium.
Obesity (Silver Spring, Md.)
Young, Kendra A KA; Palmer, Nicholette D ND; Fingerlin, Tasha E TE; Langefeld, Carl D CD; Norris, Jill M JM; Wang, Nan N; Xiang, Anny H AH; Guo, Xiuqing X; Williams, Adrienne H AH; Chen, Yii-Der I YI; Taylor, Kent D KD; Rotter, Jerome I JI; Raffel, Leslie J LJ; Goodarzi, Mark O MO; Watanabe, Richard M RM; Wagenknecht, Lynne E LE
An exploratory phenome wide association study linking asthma and liver disease genetic variants to electronic health records from the Estonian Biobank.
Plos One
James, Glen G; Reisberg, Sulev S; Lepik, Kaido K; Galwey, Nicholas N; Avillach, Paul P; Kolberg, Liis L; Mägi, Reedik R; Esko, Tõnu T; Alexander, Myriam M; Waterworth, Dawn D; Loomis, A Katrina AK; Vilo, Jaak J
Cirrhosis and Advanced Fibrosis in Hispanics in Texas: The Dominant Contribution of Central Obesity.
Plos One
Jiao, Jingjing J; Watt, Gordon P GP; Lee, MinJae M; Rahbar, Mohammad H MH; Vatcheva, Kristina P KP; Pan, Jen-Jung JJ; McCormick, Joseph B JB; Fisher-Hoch, Susan P SP; Fallon, Michael B MB; Beretta, Laura L
Nonalcoholic Steatohepatitis and Hepatic Fibrosis in HIV-1-Monoinfected Adults With Elevated Aminotransferase Levels on Antiretroviral Therapy.
Clinical Infectious Diseases : An Official Publication Of The Infectious Diseases Society Of America
Morse, Caryn G CG; McLaughlin, Mary M; Matthews, Lindsay L; Proschan, Michael M; Thomas, Francine F; Gharib, Ahmed M AM; Abu-Asab, Mones M; Orenstein, Abigail A; Engle, Ronald E RE; Hu, Xiaojun X; Lempicki, Richard R; Hadigan, Colleen C; Kleiner, David E DE; Heller, Theo T; Kovacs, Joseph A JA
Correlation between patatin-like phospholipase domain-containing protein 3 gene polymorphisms and liver cirrhosis in a chinese han population with chronic hepatitis B.
Hepatitis Monthly
Tong, Jin J; Guo, Jinjun J; Hu, Jun J; Hou, Sihui S; Zhang, Yu Y; Li, Qingling Q
Genome-wide analysis of hepatic lipid content in extreme obesity.
Acta Diabetologica
DiStefano, Johanna K JK; Kingsley, Christopher C; Craig Wood, G G; Chu, Xin X; Argyropoulos, George G; Still, Christopher D CD; Doné, Stefania Cotta SC; Legendre, Christophe C; Tembe, Waibhav W; Gerhard, Glenn S GS
Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease.
Nature Genetics
Kozlitina, Julia J; Smagris, Eriks E; Stender, Stefan S; Nordestgaard, Børge G BG; Zhou, Heather H HH; Tybjærg-Hansen, Anne A; Vogt, Thomas F TF; Hobbs, Helen H HH; Cohen, Jonathan C JC
Genetic signatures in choline and 1-carbon metabolism are associated with the severity of hepatic steatosis.
Faseb Journal : Official Publication Of The Federation Of American Societies For Experimental Biology
Corbin, Karen D KD; Abdelmalek, Manal F MF; Spencer, Melanie D MD; da Costa, Kerry-Ann KA; Galanko, Joseph A JA; Sha, Wei W; Suzuki, Ayako A; Guy, Cynthia D CD; Cardona, Diana M DM; Torquati, Alfonso A; Diehl, Anna Mae AM; Zeisel, Steven H SH
Population-based risk factors for elevated alanine aminotransferase in a South Texas Mexican-American population.
Archives Of Medical Research
Qu, Hui-Qi HQ; Li, Quan Q; Grove, Megan L ML; Lu, Yang Y; Pan, Jen-Jung JJ; Rentfro, Anne R AR; Bickel, Perry E PE; Fallon, Michael B MB; Hanis, Craig L CL; Boerwinkle, Eric E; McCormick, Joseph B JB; Fisher-Hoch, Susan P SP
PNPLA3 polymorphisms and liver aminotransferase levels in a Mexican American population.
Clinical And Investigative Medicine. Medecine Clinique Et Experimentale
Li, Quan Q; Qu, Hui-Qi HQ; Rentfro, Anne R AR; Grove, Megan L ML; Mirza, Shaper S; Lu, Yang Y; Hanis, Craig L CL; Fallon, Michael B MB; Boerwinkle, Eric E; Fisher-Hoch, Susan P SP; McCormick, Joseph B JB
Loci affecting gamma-glutamyl transferase in adults and adolescents show age × SNP interaction and cardiometabolic disease associations.
Human Molecular Genetics
Middelberg, Rita P RP; Benyamin, Beben B; de Moor, Marleen H M MH; Warrington, Nicole M NM; Gordon, Scott S; Henders, Anjali K AK; Medland, Sarah E SE; Nyholt, Dale R DR; de Geus, Eco J C EJ; Hottenga, Jouke J JJ; Willemsen, Gonneke G; Beilin, Lawrence J LJ; Mori, Trevor A TA; Wright, Margaret J MJ; Heath, Andrew C AC; Madden, Pamela A F PA; Boomsma, Dorret I DI; Pennell, Craig E CE; Montgomery, Grant W GW; Martin, Nicholas G NG; Whitfield, John B JB
The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease.
Hepatology (Baltimore, Md.)
Rotman, Yaron Y; Koh, Christopher C; Zmuda, Joseph M JM; Kleiner, David E DE; Liang, T Jake TJ; ,
Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes.
American Journal Of Human Genetics
Yuan, Xin X; Waterworth, Dawn D; Perry, John R B JR; Lim, Noha N; Song, Kijoung K; Chambers, John C JC; Zhang, Weihua W; Vollenweider, Peter P; Stirnadel, Heide H; Johnson, Toby T; Bergmann, Sven S; Beckmann, Noam D ND; Li, Yun Y; Ferrucci, Luigi L; Melzer, David D; Hernandez, Dena D; Singleton, Andrew A; Scott, James J; Elliott, Paul P; Waeber, Gerard G; Cardon, Lon L; Frayling, Timothy M TM; Kooner, Jaspal S JS; Mooser, Vincent V