Publications:

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Genetic Polymorphisms and Diversity in Nonalcoholic Fatty Liver Disease (NAFLD): A Mini Review.

Biomedicines

Sulaiman, Siti Aishah SA; Dorairaj, Vicneswarry V; Adrus, Muhammad Nafiz Haidi MNH

Publication Date: 2022-12-30

Variant appearance in text: rs2896019

PubMed Link: 36672614

Variant Present in the following documents:

• biomedicines-11-00106.pdf

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Association of Inherited Genetic Factors With Drug-Induced Hepatic Damage Among Children With Acute Lymphoblastic Leukemia.

Jama Network Open

Yang, Wenjian W; Karol, Seth E SE; Hoshitsuki, Keito K; Lee, Shawn S; Larsen, Eric C EC; Winick, Naomi N; Carroll, William L WL; Loh, Mignon L ML; Raetz, Elizabeth A EA; Hunger, Stephen P SP; Winter, Stuart S SS; Dunsmore, Kimberly P KP; Devidas, Meenakshi M; Relling, Mary V MV; Yang, Jun J JJ

Publication Date: 2022-12-01

Variant appearance in text: rs2896019

PubMed Link: 36580335

Variant Present in the following documents:

• jamanetwopen-e2248803-s001.pdf

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Contribution of PNPLA3 gene polymorphisms to hepatocellular carcinoma susceptibility in the Chinese Han population.

Bmc Medical Genomics

Gong, Dongwei D; Li, Shizong S; Yu, Zhiwei Z; Wang, Kaiqiong K; Qiao, Xin X; Wu, Changxiong C

Publication Date: 2022-11-29

Variant appearance in text: rs2896019

PubMed Link: 36447249

Variant Present in the following documents:

• Main text
• 12920_2022_Article_1394.pdf

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Genetic variation in TERT modifies the risk of hepatocellular carcinoma in alcohol-related cirrhosis: results from a genome-wide case-control study.

Gut

Buch, Stephan S; Innes, Hamish H; Lutz, Philipp Ludwig PL; Nischalke, Hans Dieter HD; Marquardt, Jens U JU; Fischer, Janett J; Weiss, Karl Heinz KH; Rosendahl, Jonas J; Marot, Astrid A; Krawczyk, Marcin M; Casper, Markus M; Lammert, Frank F; Eyer, Florian F; Vogel, Arndt A; Marhenke, Silke S; von Felden, Johann J; Sharma, Rohini R; Atkinson, Stephen Rahul SR; McQuillin, Andrew A; Nattermann, Jacob J; Schafmayer, Clemens C; Franke, Andre A; Strassburg, Christian C; Rietschel, Marcella M; Altmann, Heidi H; Sulk, Stefan S; Thangapandi, Veera Raghavan VR; Brosch, Mario M; Lackner, Carolin C; Stauber, Rudolf E RE; Canbay, Ali A; Link, Alexander A; Reiberger, Thomas T; Mandorfer, Mattias M; Semmler, Georg G; Scheiner, Bernhard B; Datz, Christian C; Romeo, Stefano S; Ginanni Corradini, Stefano S; Irving, William Lucien WL; Morling, Joanne R JR; Guha, Indra Neil IN; Barnes, Eleanor E; Ansari, M Azim MA; Quistrebert, Jocelyn J; Valenti, Luca L; Müller, Sascha A SA; Morgan, Marsha Yvonne MY; Dufour, Jean-François JF; Trebicka, Jonel J; Berg, Thomas T; Deltenre, Pierre P; Mueller, Sebastian S; Hampe, Jochen J; Stickel, Felix F

Publication Date: 2022-07-04

Variant appearance in text: rs2896019

PubMed Link: 35788059

Variant Present in the following documents:

• gutjnl-2022-327196supp001.pdf

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NAFLD polygenic risk score and risk of hepatocellular carcinoma in an East Asian population.

Hepatology Communications

Thomas, Claire E CE; Diergaarde, Brenda B; Kuipers, Allison L AL; Adibi, Jennifer J JJ; Luu, Hung N HN; Chang, Xuling X; Dorajoo, Rajkumar R; Heng, Chew-Kiat CK; Khor, Chiea-Chuen CC; Wang, Renwei R; Jin, Aizhen A; Koh, Woon-Puay WP; Yuan, Jian-Min JM

Publication Date: 2022-09

Variant appearance in text: rs2896019

PubMed Link: 35503778

Variant Present in the following documents:

• Main text
• HEP4-6-2310.pdf

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Genetic susceptibility to hepatocellular carcinoma in chromosome 22q13.31, findings of a genome-wide association study.

Jgh Open : An Open Access Journal Of Gastroenterology And Hepatology

Wang, Zhanwei Z; Budhu, Anuradha S AS; Shen, Yi Y; Wong, Linda Lou LL; Hernandez, Brenda Y BY; Tiirikainen, Maarit M; Ma, Xiaomei X; Irwin, Melinda L ML; Lu, Lingeng L; Zhao, Hongyu H; Lim, Joseph K JK; Taddei, Tamar T; Mishra, Lopa L; Pawlish, Karen K; Stroup, Antoinette A; Brown, Robert R; Nguyen, Mindie H MH; Koshiol, Jill J; Hernandez, Maria O MO; Forgues, Marshonna M; Yang, Hwai-I HI; Lee, Mei-Hsuan MH; Huang, Yu-Han YH; Iwasaki, Motoki M; Goto, Atsushi A; Suzuki, Shiori S; Matsuda, Koichi K; Tanikawa, Chizu C; Kamatani, Yoichiro Y; Mann, Dean D; Guarnera, Maria M; Shetty, Kirti K; Thomas, Claire E CE; Yuan, Jian-Min JM; Khor, Chiea Chuen CC; Koh, Woon-Puay WP; Risch, Harvey H; Wang, Xin Wei XW; Yu, Herbert H

Publication Date: 2021-12

Variant appearance in text: rs2896019

PubMed Link: 34950780

Variant Present in the following documents:

• Main text
• JGH3-5-1363.pdf

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The Risk of Cirrhosis and Its Complications Based on PNPLA3 rs738409 G Allele Frequency.

Digestive Diseases (Basel, Switzerland)

Shao, Xue X; Uojima, Haruki H; Arai, Taeang T; Ogawa, Yuji Y; Setsu, Toru T; Atsukawa, Masanori M; Furuichi, Yoshihiro Y; Arase, Yoshitaka Y; Horio, Kazue K; Hidaka, Hisashi H; Nakazawa, Takahide T; Kako, Makoto M; Kagawa, Tatehiro T; Iwakiri, Katsuhiko K; Nakajima, Atsushi A; Terai, Shuji S; Tanaka, Yasuhito Y; Koizumi, Wasaburo W

Publication Date: 2022

Variant appearance in text: rs2896019

PubMed Link: 34808618

Variant Present in the following documents:

• Main text

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Association of Genetic Risk Score With NAFLD in An Ethnically Diverse Cohort.

Hepatology Communications

Wang, Jun J; Conti, David V DV; Bogumil, David D; Sheng, Xin X; Noureddin, Mazen M; Wilkens, Lynne R LR; Le Marchand, Loic L; Rosen, Hugo R HR; Haiman, Christopher A CA; Setiawan, Veronica Wendy VW

Publication Date: 2021-10

Variant appearance in text: rs2896019

PubMed Link: 34558842

Variant Present in the following documents:

• Main text
• HEP4-5-1689.pdf

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Association between PNPLA3 rs738409 polymorphism and nonalcoholic fatty liver disease: a systematic review and meta-analysis.

Bmc Endocrine Disorders

Salari, Nader N; Darvishi, Niloufar N; Mansouri, Kamran K; Ghasemi, Hooman H; Hosseinian-Far, Melika M; Darvishi, Fateme F; Mohammadi, Masoud M

Publication Date: 2021-06-19

Variant appearance in text: rs2896019

PubMed Link: 34147109

Variant Present in the following documents:

• Main text
• 12902_2021_Article_789.pdf

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Genetic and epigenetic disease modifiers: non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD).

Translational Gastroenterology And Hepatology

Choudhary, Narendra Singh NS; Duseja, Ajay A

Publication Date: 2021

Variant appearance in text: rs2896019

PubMed Link: 33409397

Variant Present in the following documents:

• Main text

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The role of omics in the pathophysiology, diagnosis and treatment of non-alcoholic fatty liver disease.

Metabolism: Clinical And Experimental

Perakakis, Nikolaos N; Stefanakis, Konstantinos K; Mantzoros, Christos S CS

Publication Date: 2020-10

Variant appearance in text: rs2896019

PubMed Link: 32712221

Variant Present in the following documents:

• Main text
• main.pdf

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A genome-wide association study on liver enzymes in Korean population.

Plos One

Seo, Ji Yeon JY; Lee, Jong-Eun JE; Chung, Goh Eun GE; Shin, Eunsoon E; Kwak, Min-Sun MS; Yang, Jong In JI; Yim, Jeong Yoon JY

Publication Date: 2020

Variant appearance in text: rs2896019

PubMed Link: 32084209

Variant Present in the following documents:

• Main text
• pone.0229374.pdf

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PNPLA3-A Potential Therapeutic Target for Personalized Treatment of Chronic Liver Disease.

Frontiers In Medicine

Dong, Xiaocheng Charlie XC

Publication Date: 2019

Variant appearance in text: rs2896019

PubMed Link: 31921875

Variant Present in the following documents:

• Main text
• fmed-06-00304.pdf

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Genome-Wide Association Study Identifies Loci for Liver Enzyme Concentrations in Mexican Americans: The GUARDIAN Consortium.

Obesity (Silver Spring, Md.)

Young, Kendra A KA; Palmer, Nicholette D ND; Fingerlin, Tasha E TE; Langefeld, Carl D CD; Norris, Jill M JM; Wang, Nan N; Xiang, Anny H AH; Guo, Xiuqing X; Williams, Adrienne H AH; Chen, Yii-Der I YI; Taylor, Kent D KD; Rotter, Jerome I JI; Raffel, Leslie J LJ; Goodarzi, Mark O MO; Watanabe, Richard M RM; Wagenknecht, Lynne E LE

Publication Date: 2019-08

Variant appearance in text: rs2896019

PubMed Link: 31219225

Variant Present in the following documents:

• Main text
• nihms-1528348.pdf

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Genetic and Epigenetic Culprits in the Pathogenesis of Nonalcoholic Fatty Liver Disease.

Journal Of Clinical And Experimental Hepatology

Kovalic, Alexander J AJ; Banerjee, Pratik P; Tran, Quynh T QT; Singal, Ashwani K AK; Satapathy, Sanjaya K SK

Publication Date: 2018-12

Variant appearance in text: rs2896019

PubMed Link: 30564000

Variant Present in the following documents:

• Main text

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Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers.

Plos One

Kawaguchi, Takahisa T; Shima, Toshihide T; Mizuno, Masayuki M; Mitsumoto, Yasuhide Y; Umemura, Atsushi A; Kanbara, Yoshihiro Y; Tanaka, Saiyu S; Sumida, Yoshio Y; Yasui, Kohichiro K; Takahashi, Meiko M; Matsuo, Keitaro K; Itoh, Yoshito Y; Tokushige, Katsutoshi K; Hashimoto, Etsuko E; Kiyosawa, Kendo K; Kawaguchi, Masanori M; Itoh, Hiroyuki H; Uto, Hirofumi H; Komorizono, Yasuji Y; Shirabe, Ken K; Takami, Shiro S; Takamura, Toshinari T; Kawanaka, Miwa M; Yamada, Ryo R; Matsuda, Fumihiko F; Okanoue, Takeshi T

Publication Date: 2018

Variant appearance in text: rs2896019

PubMed Link: 29385134

Variant Present in the following documents:

• Main text
• pone.0185490.pdf

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Genetic variants in COL13A1, ADIPOQ and SAMM50, in addition to the PNPLA3 gene, confer susceptibility to elevated transaminase levels in an admixed Mexican population.

Experimental And Molecular Pathology

Larrieta-Carrasco, Elena E; Flores, Yvonne N YN; Macías-Kauffer, Luis R LR; Ramírez-Palacios, Paula P; Quiterio, Manuel M; Ramírez-Salazar, Eric G EG; León-Mimila, Paola P; Rivera-Paredez, Berenice B; Cabrera-Álvarez, Guillermo G; Canizales-Quinteros, Samuel S; Zhang, Zuo-Feng ZF; López-Pérez, Tania V TV; Salmerón, Jorge J; Velázquez-Cruz, Rafael R

Publication Date: 2018-02

Variant appearance in text: rs2896019

PubMed Link: 29307798

Variant Present in the following documents:

• Main text

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Association of patatin-like phospholipase domain-containing protein 3 gene polymorphisms with susceptibility of nonalcoholic fatty liver disease in a Han Chinese population.

Medicine

Song, Guohe G; Xiao, Chao C; Wang, Kai K; Wang, Yupeng Y; Chen, Jian J; Yu, Yang Y; Wang, Zhaowen Z; Deng, Guilong G; Sun, Xing X; Zhong, Lin L; Zhou, Chongzhi C; Qi, Xiaosheng X; Wang, Shuyun S; Peng, Zhihai Z; Wang, Xiaoliang X

Publication Date: 2016-08

Variant appearance in text: rs2896019

PubMed Link: 27537584

Variant Present in the following documents:

• Main text
• medi-95-e4569.pdf

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Genetic analysis of nonalcoholic fatty liver disease within a Caribbean-Hispanic population.

Molecular Genetics & Genomic Medicine

Edelman, Deborah D; Kalia, Harmit H; Delio, Maria M; Alani, Mustafa M; Krishnamurthy, Karthik K; Abd, Mortadha M; Auton, Adam A; Wang, Tao T; Wolkoff, Allan W AW; Morrow, Bernice E BE

Publication Date: 2015-11

Variant appearance in text: PNPLA3: 979+542T>G; rs2896019

PubMed Link: 26740948

Variant Present in the following documents:

• Main text
• MGG3-3-558.pdf

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Role of genetic polymorphisms in hepatitis C virus chronic infection.

World Journal Of Clinical Cases

Coppola, Nicola N; Pisaturo, Mariantonietta M; Sagnelli, Caterina C; Onorato, Lorenzo L; Sagnelli, Evangelista E

Publication Date: 2015-09-16

Variant appearance in text: rs2896019

PubMed Link: 26380828

Variant Present in the following documents:

• Main text

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Liver enzymes, metabolomics and genome-wide association studies: from systems biology to the personalized medicine.

World Journal Of Gastroenterology

Sookoian, Silvia S; Pirola, Carlos J CJ

Publication Date: 2015-01-21

Variant appearance in text: rs2896019

PubMed Link: 25624707

Variant Present in the following documents:

• Main text

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Genome-wide analysis of hepatic lipid content in extreme obesity.

Acta Diabetologica

DiStefano, Johanna K JK; Kingsley, Christopher C; Craig Wood, G G; Chu, Xin X; Argyropoulos, George G; Still, Christopher D CD; Doné, Stefania Cotta SC; Legendre, Christophe C; Tembe, Waibhav W; Gerhard, Glenn S GS

Publication Date: 2015-04

Variant appearance in text: rs2896019

PubMed Link: 25246029

Variant Present in the following documents:

• Main text

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Non-alcoholic fatty liver disease and type 2 diabetes mellitus: the liver disease of our age?

World Journal Of Gastroenterology

Firneisz, Gábor G

Publication Date: 2014-07-21

Variant appearance in text: rs2896019

PubMed Link: 25083080

Variant Present in the following documents:

• Main text

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Clinical differences between alcoholic liver disease and nonalcoholic fatty liver disease.

World Journal Of Gastroenterology

Toshikuni, Nobuyuki N; Tsutsumi, Mikihiro M; Arisawa, Tomiyasu T

Publication Date: 2014-07-14

Variant appearance in text: rs2896019

PubMed Link: 25024597

Variant Present in the following documents:

• Main text

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The effect of PNPLA3 on fibrosis progression and development of hepatocellular carcinoma: a meta-analysis.

The American Journal Of Gastroenterology

Singal, Amit G AG; Manjunath, Hema H; Yopp, Adam C AC; Beg, Muhammad S MS; Marrero, Jorge A JA; Gopal, Purva P; Waljee, Akbar K AK

Publication Date: 2014-03

Variant appearance in text: rs2896019

PubMed Link: 24445574

Variant Present in the following documents:

• Main text

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Genetic polymorphisms of the human PNPLA3 gene are strongly associated with severity of non-alcoholic fatty liver disease in Japanese.

Plos One

Kawaguchi, Takahisa T; Sumida, Yoshio Y; Umemura, Atsushi A; Matsuo, Keitaro K; Takahashi, Meiko M; Takamura, Toshinari T; Yasui, Kohichiroh K; Saibara, Toshiji T; Hashimoto, Etsuko E; Kawanaka, Miwa M; Watanabe, Sumio S; Kawata, Sumio S; Imai, Yasuharu Y; Kokubo, Miki M; Shima, Toshihide T; Park, Hyohun H; Tanaka, Hideo H; Tajima, Kazuo K; Yamada, Ryo R; Matsuda, Fumihiko F; Okanoue, Takeshi T; ,

Publication Date: 2012

Variant appearance in text: rs2896019

PubMed Link: 22719876

Variant Present in the following documents:

• Main text
• pone.0038322.pdf

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The association of genetic variants with hepatic steatosis in patients with genotype 1 chronic hepatitis C infection.

Digestive Diseases And Sciences

Clark, Paul J PJ; Thompson, Alexander J AJ; Zhu, Qianqian Q; Vock, David M DM; Zhu, Mingfu M; Patel, Keyur K; Harrison, Stephen A SA; Naggie, Susanna S; Ge, Dongliang D; Tillmann, Hans L HL; Urban, Thomas J TJ; Shianna, Kevin K; Fellay, Jacques J; Goodman, Zachary Z; Noviello, Stephanie S; Pedicone, Lisa D LD; Afdhal, Nezam N; Sulkowski, Mark M; Albrecht, Janice K JK; Goldstein, David B DB; McHutchison, John G JG; Muir, Andrew J AJ

Publication Date: 2012-08

Variant appearance in text: rs2896019

PubMed Link: 22543885

Variant Present in the following documents:

• Main text

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