Publications:

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Effect of CYP3A4 and PPARA polymorphism on concentration-to-dose ratio and adverse effects of tacrolimus in Pakistani liver transplant recipients.

Pakistan Journal Of Medical Sciences

Azam, Fahad F; Khan, Moosa M; Shaheen, Abida A; Bhatti, AbuBakar Hafeez AH

Publication Date: 2022

Variant appearance in text: rs4823613

PubMed Link: 36246675

Variant Present in the following documents:

• Main text
• PJMS-38-1893.pdf

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Insights into the Pharmacogenetics of Tacrolimus Pharmacokinetics and Pharmacodynamics.

Pharmaceutics

Brunet, Mercè M; Pastor-Anglada, Marçal M

Publication Date: 2022-08-23

Variant appearance in text: PPARA: 208+3819A>G

PubMed Link: 36145503

Variant Present in the following documents:

• Main text
• pharmaceutics-14-01755.pdf

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Why We Need to Take a Closer Look at Genetic Contributions to CYP3A Activity.

Frontiers In Pharmacology

Zhai, Qinglian Q; van der Lee, Maaike M; van Gelder, Teun T; Swen, Jesse J JJ

Publication Date: 2022

Variant appearance in text: rs4823613

PubMed Link: 35784699

Variant Present in the following documents:

• Main text
• fphar-13-912618.pdf

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SwissPKcdw - A clinical data warehouse for the optimization of pediatric dosing regimens.

Cpt: Pharmacometrics & Systems Pharmacology

Goers, Roland R; Coman Schmid, Diana D; Jäggi, Vera F VF; Paioni, Paolo P; Okoniewski, Michal J MJ; Parker, Althea A; Bangerter, Beat B; Georgakopoulou, Sofia S; Sengstag, Thierry T; Bielicki, Julia J; Tilen, Romy R; Vermeul, Swen S; Krämer, Stefanie D SD; Berger, Christoph C; Rinn, Bernd B; Meyer Zu Schwabedissen, Henriette E HE

Publication Date: 2021-11-02

Variant appearance in text: rs4823613

PubMed Link: 34729953

Variant Present in the following documents:

• Main text
• PSP4-10-1578.pdf

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SwissPKcdw - A clinical data warehouse for the optimization of pediatric dosing regimens.

Cpt: Pharmacometrics & Systems Pharmacology

Goers, Roland R; Coman Schmid, Diana D; Jäggi, Vera F VF; Paioni, Paolo P; Okoniewski, Michal J MJ; Parker, Althea A; Bangerter, Beat B; Georgakopoulou, Sofia S; Sengstag, Thierry T; Bielicki, Julia J; Tilen, Romy R; Vermeul, Swen S; Krämer, Stefanie D SD; Berger, Christoph C; Rinn, Bernd B; Meyer Zu Schwabedissen, Henriette E HE

Publication Date: 2021-12

Variant appearance in text: rs4823613

PubMed Link: 34729953

Variant Present in the following documents:

• Main text
• PSP4-10-1578.pdf

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Polymorphisms analysis for association between ADIPO signaling pathway and genetic susceptibility to T2DM in Chinese han population.

Adipocyte

Yu, Haibing H; Hu, Wei W; Lin, Chunwen C; Xu, Lin L; Liu, Hao H; Luo, Ling L; Chen, Rong R; Huang, Jialu J; Chen, Weiying W; Yang, Chen C; Kong, Danli D; Ding, Yuanlin Y

Publication Date: 2021-12

Variant appearance in text: rs4823613

PubMed Link: 34641739

Variant Present in the following documents:

• Main text
• KADI_10_1978728.pdf

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Diabetes and Cardiovascular Risk in Renal Transplant Patients.

International Journal Of Molecular Sciences

Rysz, Jacek J; Franczyk, Beata B; Radek, Maciej M; Ciałkowska-Rysz, Aleksandra A; Gluba-Brzózka, Anna A

Publication Date: 2021-03-26

Variant appearance in text: rs4823613

PubMed Link: 33810367

Variant Present in the following documents:

• Main text
• ijms-22-03422.pdf

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Effect of CYP3A4*22 and PPAR-α Genetic Variants on Platelet Reactivity in Patients Treated with Clopidogrel and Lipid-Lowering Drugs Undergoing Elective Percutaneous Coronary Intervention.

Genes

Bergmeijer, Thomas O TO; Yasmina, Alfi A; Vos, Gerrit J A GJA; Janssen, Paul W A PWA; Hackeng, Christian M CM; Kelder, Johannes C JC; Verma, Shefali S SS; Ritchie, Marylyn D MD; Gong, Li L; Klein, Teri E TE; Icpc Investigators, ; de Boer, Anthonius A; Klungel, Olaf H OH; Ten Berg, Jurriën M JM; Deneer, Vera H M VHM

Publication Date: 2020-09-11

Variant appearance in text: rs4823613

PubMed Link: 32932966

Variant Present in the following documents:

• Main text
• genes-11-01068-s001.pdf
• genes-11-01068.pdf

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Importance of genetic polymorphisms in liver transplantation outcomes.

World Journal Of Gastroenterology

Kelava, Tomislav T; Turcic, Petra P; Markotic, Antonio A; Ostojic, Ana A; Sisl, Dino D; Mrzljak, Anna A

Publication Date: 2020-03-28

Variant appearance in text: rs4823613

PubMed Link: 32256016

Variant Present in the following documents:

• Main text
• WJG-26-1273.pdf

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Early Tacrolimus Concentrations After Lung Transplant Are Predicted by Combined Clinical and Genetic Factors and Associated With Acute Kidney Injury.

Clinical Pharmacology And Therapeutics

Miano, Todd A TA; Flesch, Judd D JD; Feng, Rui R; Forker, Caitlin M CM; Brown, Melanie M; Oyster, Michelle M; Kalman, Laurel L; Rushefski, Melanie M; Cantu, Edward E; Porteus, Mary M; Yang, Wei W; Localio, A Russel AR; Diamond, Joshua M JM; Christie, Jason D JD; Shashaty, Michael G S MGS

Publication Date: 2020-02

Variant appearance in text: PPARA: 208+3819A>G

PubMed Link: 31513279

Variant Present in the following documents:

• Main text

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Population pharmacokinetics of cyclosporine in Chinese children receiving hematopoietic stem cell transplantation.

Acta Pharmacologica Sinica

Li, Tai-Feng TF; Hu, Lei L; Ma, Xiao-Lu XL; Huang, Lin L; Liu, Xue-Mei XM; Luo, Xing-Xian XX; Feng, Wan-Yu WY; Wu, Chun-Fu CF

Publication Date: 2019-12

Variant appearance in text: rs4823613

PubMed Link: 31341257

Variant Present in the following documents:

• Main text
• 41401_2019_Article_277.pdf

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Pharmacogenetics of artemether-lumefantrine influence on nevirapine disposition: Clinically significant drug-drug interaction?

British Journal Of Clinical Pharmacology

Abdullahi, Sa'ad T ST; Olagunju, Adeniyi A; Soyinka, Julius O JO; Bolarinwa, Rahman A RA; Olarewaju, Olusola J OJ; Bakare-Odunola, Moji T MT; Owen, Andrew A; Khoo, Saye S

Publication Date: 2019-03

Variant appearance in text: rs4823613

PubMed Link: 30471138

Variant Present in the following documents:

• Main text

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Pharmacokinetics, Pharmacodynamics and Pharmacogenetics of Tacrolimus in Kidney Transplantation.

Current Drug Metabolism

Yu, Meng M; Liu, Mouze M; Zhang, Wei W; Ming, Yingzi Y

Publication Date: 2018

Variant appearance in text: PPARA: 208+3819A>G

PubMed Link: 29380698

Variant Present in the following documents:

• Main text
• CDM-19-513.pdf

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Attempted validation of 44 reported SNPs associated with tacrolimus troughs in a cohort of kidney allograft recipients.

Pharmacogenomics

Oetting, William S WS; Wu, Baolin B; Schladt, David P DP; Guan, Weihua W; Remmel, Rory P RP; Dorr, Casey C; Mannon, Roslyn B RB; Matas, Arthur J AJ; Israni, Ajay K AK; Jacobson, Pamala A PA

Publication Date: 2018-02

Variant appearance in text: rs4823613

PubMed Link: 29318894

Variant Present in the following documents:

• Main text

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Genetic factors in pathogenesis of diabetes mellitus after kidney transplantation.

Therapeutics And Clinical Risk Management

Tarnowski, Maciej M; Słuczanowska-Głabowska, Sylwia S; Pawlik, Andrzej A; Mazurek-Mochol, Małgorzata M; Dembowska, Elżbieta E

Publication Date: 2017

Variant appearance in text: rs4823613

PubMed Link: 28435278

Variant Present in the following documents:

• Main text
• tcrm-13-439.pdf

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The Pharmacogenetics of Tacrolimus in Corticosteroid-Sparse Pediatric and Adult Kidney Transplant Recipients.

Drugs In R&D

Madsen, Mads Juul MJ; Bergmann, Troels K TK; Brøsen, Kim K; Thiesson, Helle Charlotte HC

Publication Date: 2017-06

Variant appearance in text: PPARA: 208+3819A>G; rs4823613

PubMed Link: 28229376

Variant Present in the following documents:

• Main text
• 40268_2017_Article_177.pdf

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Identification of Haplotype Tag Single-Nucleotide Polymorphisms within the PPAR Family Genes and Their Clinical Relevance in Patients with Major Trauma.

International Journal Of Environmental Research And Public Health

Gao, Jun-Wei JW; Zeng, Ling L; Zhang, An-Qiang AQ; Wang, Xiao X; Pan, Wei W; Du, Ding-Yuan DY; Zhang, Lian-Yang LY; Gu, Wei W; Jiang, Jian-Xin JX

Publication Date: 2016-03-26

Variant appearance in text: rs4823613

PubMed Link: 27023591

Variant Present in the following documents:

• Main text

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Peroxisome proliferator-activated receptor alpha, PPARα, directly regulates transcription of cytochrome P450 CYP2C8.

Frontiers In Pharmacology

Thomas, Maria M; Winter, Stefan S; Klumpp, Britta B; Turpeinen, Miia M; Klein, Kathrin K; Schwab, Matthias M; Zanger, Ulrich M UM

Publication Date: 2015

Variant appearance in text: rs4823613

PubMed Link: 26582990

Variant Present in the following documents:

• Main text
• fphar-06-00261.pdf

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The Rotterdam Study: 2016 objectives and design update.

European Journal Of Epidemiology

Hofman, Albert A; Brusselle, Guy G O GG; Darwish Murad, Sarwa S; van Duijn, Cornelia M CM; Franco, Oscar H OH; Goedegebure, André A; Ikram, M Arfan MA; Klaver, Caroline C W CC; Nijsten, Tamar E C TE; Peeters, Robin P RP; Stricker, Bruno H Ch BH; Tiemeier, Henning W HW; Uitterlinden, André G AG; Vernooij, Meike W MW

Publication Date: 2015-08

Variant appearance in text: rs4823613

PubMed Link: 26386597

Variant Present in the following documents:

• Main text

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Role of peroxisome proliferator-activated receptors gene polymorphisms in type 2 diabetes and metabolic syndrome.

World Journal Of Diabetes

Dong, Chen C; Zhou, Hui H; Shen, Chong C; Yu, Lu-Gang LG; Ding, Yi Y; Zhang, Yong-Hong YH; Guo, Zhi-Rong ZR

Publication Date: 2015-05-15

Variant appearance in text: rs4823613

PubMed Link: 25987964

Variant Present in the following documents:

• Main text

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Parsing interindividual drug variability: an emerging role for systems pharmacology.

Wiley Interdisciplinary Reviews. Systems Biology And Medicine

Turner, Richard M RM; Park, B Kevin BK; Pirmohamed, Munir M

Publication Date: 2015

Variant appearance in text: rs4823613

PubMed Link: 25950758

Variant Present in the following documents:

• Main text

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Role of pharmacogenomics in dialysis and transplantation.

Current Opinion In Nephrology And Hypertension

Birdwell, Kelly K

Publication Date: 2014-11

Variant appearance in text: rs4823613

PubMed Link: 25162201

Variant Present in the following documents:

• Main text

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Identification of genes contributing to cardiovascular disease in overweight and obese individuals from West Virginia.

The West Virginia Medical Journal

Dementieva, Yulia Y; Green, Todd L TL; Primerano, Donald A DA; Wei, Liping L; Denvir, James J; Wehner, Paulette P; Dodson, Sarah S; Flood, Mark R MR; Pollock, Bonnie A BA; Huff, Melinda M; Hill, Contessa C; Kreisberg, Robert R; Francis, Amanda A; Morrison, Katie K; Blackwood, Holly H; Davis, Mary M; Lee, Huey Miin HM; Warren, Stafford S; ,

Publication Date: 2012

Variant appearance in text: rs4823613

PubMed Link: 25134189

Variant Present in the following documents:

• Main text

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The influence of CYP3A, PPARA, and POR genetic variants on the pharmacokinetics of tacrolimus and cyclosporine in renal transplant recipients.

European Journal Of Clinical Pharmacology

Lunde, Ingrid I; Bremer, Sara S; Midtvedt, Karsten K; Mohebi, Beata B; Dahl, Miriam M; Bergan, Stein S; Åsberg, Anders A; Christensen, Hege H

Publication Date: 2014-06

Variant appearance in text: PPARA: 208+3819A>G; rs4823613

PubMed Link: 24658827

Variant Present in the following documents:

• Main text

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More potent lipid-lowering effect by rosuvastatin compared with fluvastatin in everolimus-treated renal transplant recipients.

Transplantation

Robertsen, Ida I; Asberg, Anders A; Granseth, Tone T; Vethe, Nils Tore NT; Akhlaghi, Fatemeh F; Ghareeb, Mwlod M; Molden, Espen E; Reier-Nilsen, Morten M; Holdaas, Hallvard H; Midtvedt, Karsten K

Publication Date: 2014-06-27

Variant appearance in text: rs4823613

PubMed Link: 24521776

Variant Present in the following documents:

• Main text

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Cytochrome P450 3A4*22, PPAR-α, and ARNT polymorphisms and clopidogrel response.

Clinical Pharmacology : Advances And Applications

Kreutz, Rolf P RP; Owens, Janelle J; Jin, Yan Y; Nystrom, Perry P; Desta, Zeruesenay Z; Kreutz, Yvonne Y; Breall, Jeffrey A JA; Li, Lang L; Chiang, Chienwei C; Kovacs, Richard J RJ; Flockhart, David A DA

Publication Date: 2013

Variant appearance in text: rs4823613

PubMed Link: 24353446

Variant Present in the following documents:

• Main text
• cpaa-5-185.pdf

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