TIGIT c.673_674delinsGC ;(p.Y225A)

Variant ID: 3-114026916-TA-GC

NM_173799.3(TIGIT):c.673_674delinsGC;(p.Y225A)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Emergence of the CD226 Axis in Cancer Immunotherapy.

Frontiers In Immunology
Conner, Michael M; Hance, Ken W KW; Yadavilli, Sapna S; Smothers, James J; Waight, Jeremy D JD
Publication Date: 2022

Variant appearance in text: TIGIT: Y225A
PubMed Link: 35812451
Variant Present in the following documents:
  • Main text
  • fimmu-13-914406.pdf
View BVdb publication page



TIGIT/CD226 Axis Regulates Anti-Tumor Immunity.

Pharmaceuticals (Basel, Switzerland)
Yeo, Jinah J; Ko, Minkyung M; Lee, Dong-Hee DH; Park, Yoon Y; Jin, Hyung-Seung HS
Publication Date: 2021-02-28

Variant appearance in text: TIGIT: Y225A
PubMed Link: 33670993
Variant Present in the following documents:
  • Main text
  • pharmaceuticals-14-00200.pdf
View BVdb publication page



Hitting the complexity of the TIGIT-CD96-CD112R-CD226 axis for next-generation cancer immunotherapy.

Bmb Reports
Jin, Hyung-Seung HS; Park, Yoon Y
Publication Date: 2021-01

Variant appearance in text: TIGIT: Y225A
PubMed Link: 33298247
Variant Present in the following documents:
  • Main text
View BVdb publication page



Immune checkpoint molecules in natural killer cells as potential targets for cancer immunotherapy.

Signal Transduction And Targeted Therapy
Cao, Yuqing Y; Wang, Xiaoyu X; Jin, Tianqiang T; Tian, Yu Y; Dai, Chaoliu C; Widarma, Crystal C; Song, Rui R; Xu, Feng F
Publication Date: 2020-10-29

Variant appearance in text: TIGIT: Y225A
PubMed Link: 33122640
Variant Present in the following documents:
  • Main text
  • 41392_2020_Article_348.pdf
View BVdb publication page



T-cell immunoglobulin and ITIM domain (TIGIT) receptor/poliovirus receptor (PVR) ligand engagement suppresses interferon-γ production of natural killer cells via β-arrestin 2-mediated negative signaling.

The Journal Of Biological Chemistry
Li, Man M; Xia, Pengyan P; Du, Ying Y; Liu, Shengwu S; Huang, Guanling G; Chen, Jun J; Zhang, Honglian H; Hou, Ning N; Cheng, Xuan X; Zhou, Luyu L; Li, Peifeng P; Yang, Xiao X; Fan, Zusen Z
Publication Date: 2014-06-20

Variant appearance in text: TIGIT: Y225A
PubMed Link: 24817116
Variant Present in the following documents:
  • Main text
View BVdb publication page



Recruitment of Grb2 and SHIP1 by the ITT-like motif of TIGIT suppresses granule polarization and cytotoxicity of NK cells.

Cell Death And Differentiation
Liu, S S; Zhang, H H; Li, M M; Hu, D D; Li, C C; Ge, B B; Jin, B B; Fan, Z Z
Publication Date: 2013-03

Variant appearance in text: TIGIT: Y225A
PubMed Link: 23154388
Variant Present in the following documents:
  • Main text
View BVdb publication page