Effect of polymorphisms in drug metabolism and transportation on plasma concentration of atorvastatin and its metabolites in patients with chronic kidney disease.
Frontiers In Pharmacology
Jiang, Zebin Z; Wu, Zemin Z; Liu, Ruixue R; Du, Qin Q; Fu, Xian X; Li, Min M; Kuang, Yongjun Y; Lin, Shen S; Wu, Jiaxuan J; Xie, Weiji W; Shi, Ganggang G; Peng, Yanqiang Y; Zheng, Fuchun F
Combined electronic medical records and gene polymorphism characteristics to establish an anti-tuberculosis drug-induced hepatic injury (ATDH) prediction model and evaluate the prediction value.
The Effects of Cumulative Dose and Polymorphisms in CYP2B6 on the Mitotane Plasma Trough Concentrations in Chinese Patients With Advanced Adrenocortical Carcinoma.
Frontiers In Oncology
Liu, Xin X; Shang, Junmei J; Fu, Qiang Q; Lu, Lin L; Deng, Jianhua J; Tang, Yan Y; Li, Jiantao J; Mei, Dan D; Zhang, Bo B; Zhang, Shuyang S
Retrospective Analysis of the Risk Factors of Perioperative Bacterial Infection and Correlation with Clinical Prognosis in Kidney Transplant Recipients.
Warfarin Pharmacogenomics for Precision Medicine in Real-Life Clinical Practice in Southern Africa: Harnessing 73 Variants in 29 Pharmacogenes.
Omics : A Journal Of Integrative Biology
Muyambo, Sarudzai S; Ndadza, Arinao A; Soko, Nyarai D ND; Kruger, Bianca B; Kadzirange, Gerard G; Chimusa, Emile E; Masimirembwa, Collen M CM; Ntsekhe, Mpiko M; Nhachi, Charles F B CFB; Dandara, Collet C
Warfarin Pharmacogenomics for Precision Medicine in Real-Life Clinical Practice in Southern Africa: Harnessing 73 Variants in 29 Pharmacogenes.
Omics : A Journal Of Integrative Biology
Muyambo, Sarudzai S; Ndadza, Arinao A; Soko, Nyarai D ND; Kruger, Bianca B; Kadzirange, Gerard G; Chimusa, Emile E; Masimirembwa, Collen M CM; Ntsekhe, Mpiko M; Nhachi, Charles F B CFB; Dandara, Collet C
Pharmacogenetic predictors of nevirapine pharmacokinetics in Ghanaian children living with HIV with or without TB coinfection.
Infection, Genetics And Evolution : Journal Of Molecular Epidemiology And Evolutionary Genetics In Infectious Diseases
Langaee, Taimour T; Al-Shaer, Mohammad H MH; Gong, Yan Y; Lima, Elizabeth E; Antwi, Sampson S; Enimil, Anthony A; Dompreh, Albert A; Yang, Hongmei H; Alghamdi, Wael A WA; Wiesner, Lubbe L; Peloquin, Charles A CA; Kwara, Awewura A
Associations between Pregnane X Receptor and Breast Cancer Growth and Progression.
Cells
Creamer, Bradley A BA; Sloan, Shelly N B SNB; Dennis, Jennifer F JF; Rogers, Robert R; Spencer, Sidney S; McCuen, Andrew A; Persaud, Purnadeo P; Staudinger, Jeff L JL
Steroid hormone-related polymorphisms associate with the development of bone erosions in rheumatoid arthritis and help to predict disease progression: Results from the REPAIR consortium.
Scientific Reports
Sánchez-Maldonado, Jose M JM; Cáliz, Rafael R; Canet, Luz L; Horst, Rob Ter RT; Bakker, Olivier O; den Broeder, Alfons A AA; Martínez-Bueno, Manuel M; Canhão, Helena H; Rodríguez-Ramos, Ana A; Lupiañez, Carmen B CB; Soto-Pino, María José MJ; García, Antonio A; Pérez-Pampin, Eva E; González-Utrilla, Alfonso A; Escudero, Alejandro A; Segura-Catena, Juana J; Netea-Maier, Romana T RT; Ferrer, Miguel Ángel MÁ; Collantes-Estevez, Eduardo E; López Nevot, Miguel Ángel MÁ; Li, Yang Y; Jurado, Manuel M; Fonseca, João E JE; Netea, Mihai G MG; Coenen, Marieke J H MJH; Sainz, Juan J
Impact of NR1I2, adenosine triphosphate-binding cassette transporters genetic polymorphisms on the pharmacokinetics of ginsenoside compound K in healthy Chinese volunteers.
Journal Of Ginseng Research
Zhou, Luping L; Chen, Lulu L; Wang, Yaqin Y; Huang, Jie J; Yang, Guoping G; Tan, Zhirong Z; Wang, Yicheng Y; Liao, Jianwei J; Zhou, Gan G; Hu, Kai K; Li, Zhenyu Z; Ouyang, Dongsheng D
Attempted validation of 44 reported SNPs associated with tacrolimus troughs in a cohort of kidney allograft recipients.
Pharmacogenomics
Oetting, William S WS; Wu, Baolin B; Schladt, David P DP; Guan, Weihua W; Remmel, Rory P RP; Dorr, Casey C; Mannon, Roslyn B RB; Matas, Arthur J AJ; Israni, Ajay K AK; Jacobson, Pamala A PA
Publication Date: 2018-02
Variant appearance in text: NR1I2: 795-93G>A; rs6785049
Pharmacogenetic analysis of high-dose methotrexate treatment in children with osteosarcoma.
Oncotarget
Hegyi, Marta M; Arany, Adam A; Semsei, Agnes F AF; Csordas, Katalin K; Eipel, Oliver O; Gezsi, Andras A; Kutszegi, Nora N; Csoka, Monika M; Muller, Judit J; Erdelyi, Daniel J DJ; Antal, Peter P; Szalai, Csaba C; Kovacs, Gabor T GT
An Expanded Analysis of Pharmacogenetics Determinants of Efavirenz Response that Includes 3'-UTR Single Nucleotide Polymorphisms among Black South African HIV/AIDS Patients.
Frontiers In Genetics
Swart, Marelize M; Evans, Jonathan J; Skelton, Michelle M; Castel, Sandra S; Wiesner, Lubbe L; Smith, Peter J PJ; Dandara, Collet C
Comprehensive Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Evaluation of Once-Daily Efavirenz 400 and 600 mg in Treatment-Naïve HIV-Infected Patients at 96 Weeks: Results of the ENCORE1 Study.
Clinical Pharmacokinetics
Dickinson, Laura L; Amin, Janaki J; Else, Laura L; Boffito, Marta M; Egan, Deirdre D; Owen, Andrew A; Khoo, Saye S; Back, David D; Orrell, Catherine C; Clarke, Amanda A; Losso, Marcelo M; Phanuphak, Praphan P; Carey, Dianne D; Cooper, David A DA; Emery, Sean S; Puls, Rebekah R
Are Immune Modulating Single Nucleotide Polymorphisms Associated with Necrotizing Enterocolitis?
Scientific Reports
Franklin, Ashanti L AL; Said, Mariam M; Cappiello, Clint D CD; Gordish-Dressman, Heather H; Tatari-Calderone, Zohreh Z; Vukmanovic, Stanislav S; Rais-Bahrami, Khodayar K; Luban, Naomi L C NL; Devaney, Joseph M JM; Sandler, Anthony D AD
Gender-Dimorphic Impact of PXR Genotype and Haplotype on Hepatotoxicity During Antituberculosis Treatment.
Medicine
Wang, Jann Yuan JY; Tsai, Ching Hui CH; Lee, Yungling Leo YL; Lee, Li Na LN; Hsu, Chia Lin CL; Chang, Hsiu Ching HC; Chen, Jong Ming JM; Hsu, Cheng An CA; Yu, Chong Jen CJ; Yang, Pan Chyr PC
The Affymetrix DMET Plus platform reveals unique distribution of ADME-related variants in ethnic Arabs.
Disease Markers
Wakil, Salma M SM; Nguyen, Cao C; Muiya, Nzioka P NP; Andres, Editha E; Lykowska-Tarnowska, Agnieszka A; Baz, Batoul B; Tahir, Asma I AI; Meyer, Brian F BF; Morahan, Grant G; Dzimiri, Nduna N
IL8 polymorphisms and overall survival in pazopanib- or sunitinib-treated patients with renal cell carcinoma.
British Journal Of Cancer
Xu, C-F CF; Johnson, T T; Garcia-Donas, J J; Choueiri, T K TK; Sternberg, C N CN; Davis, I D ID; Bing, N N; Deen, K C KC; Xue, Z Z; McCann, L L; Esteban, E E; Whittaker, J C JC; Spraggs, C F CF; Rodríguez-Antona, C C; Pandite, L N LN; Motzer, R J RJ
Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus.
Gastroenterology
Palles, Claire C; Chegwidden, Laura L; Li, Xinzhong X; Findlay, John M JM; Farnham, Garry G; Castro Giner, Francesc F; Peppelenbosch, Maikel P MP; Kovac, Michal M; Adams, Claire L CL; Prenen, Hans H; Briggs, Sarah S; Harrison, Rebecca R; Sanders, Scott S; MacDonald, David D; Haigh, Chris C; Tucker, Art A; Love, Sharon S; Nanji, Manoj M; deCaestecker, John J; Ferry, David D; Rathbone, Barrie B; Hapeshi, Julie J; Barr, Hugh H; Moayyedi, Paul P; Watson, Peter P; Zietek, Barbara B; Maroo, Neera N; Gay, Laura L; Underwood, Tim T; Boulter, Lisa L; McMurtry, Hugh H; Monk, David D; Patel, Praful P; Ragunath, Krish K; Al Dulaimi, David D; Murray, Iain I; Koss, Konrad K; Veitch, Andrew A; Trudgill, Nigel N; Nwokolo, Chuka C; Rembacken, Bjorn B; Atherfold, Paul P; Green, Elaine E; Ang, Yeng Y; Kuipers, Ernst J EJ; Chow, Wu W; Paterson, Stuart S; Kadri, Sudarshan S; Beales, Ian I; Grimley, Charles C; Mullins, Paul P; Beckett, Conrad C; Farrant, Mark M; Dixon, Andrew A; Kelly, Sean S; Johnson, Matthew M; Wajed, Shahjehan S; Dhar, Anjan A; Sawyer, Elinor E; Roylance, Rebecca R; Onstad, Lynn L; Gammon, Marilie D MD; Corley, Douglas A DA; Shaheen, Nicholas J NJ; Bird, Nigel C NC; Hardie, Laura J LJ; Reid, Brian J BJ; Ye, Weimin W; Liu, Geoffrey G; Romero, Yvonne Y; Bernstein, Leslie L; Wu, Anna H AH; Casson, Alan G AG; Fitzgerald, Rebecca R; Whiteman, David C DC; Risch, Harvey A HA; Levine, David M DM; Vaughan, Tom L TL; Verhaar, Auke P AP; van den Brande, Jan J; Toxopeus, Eelke L EL; Spaander, Manon C MC; Wijnhoven, Bas P L BP; van der Laan, Luc J W LJ; Krishnadath, Kausilia K; Wijmenga, Cisca C; Trynka, Gosia G; McManus, Ross R; Reynolds, John V JV; O'Sullivan, Jacintha J; MacMathuna, Padraic P; McGarrigle, Sarah A SA; Kelleher, Dermot D; Vermeire, Severine S; Cleynen, Isabelle I; Bisschops, Raf R; Tomlinson, Ian I; Jankowski, Janusz J