PPARG c.-9+32385C>T

Variant ID: 3-12386337-C-T

NM_138711.6(PPARG):c.-9+32385C>T

This variant was identified in 25 publications

View GRCh38 version.




Publications:


Common Genetic Aberrations Associated with Metabolic Interferences in Human Type-2 Diabetes and Acute Myeloid Leukemia: A Bioinformatics Approach.

International Journal Of Molecular Sciences
Kyriakou, Theodora-Christina TC; Papageorgis, Panagiotis P; Christodoulou, Maria-Ioanna MI
Publication Date: 2021-08-28

Variant appearance in text: rs4684847
PubMed Link: 34502231
Variant Present in the following documents:
  • Main text
  • ijms-22-09322.pdf
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Genetic Variants in Transcription Factor Binding Sites in Humans: Triggered by Natural Selection and Triggers of Diseases.

International Journal Of Molecular Sciences
Tseng, Chia-Chun CC; Wong, Man-Chun MC; Liao, Wei-Ting WT; Chen, Chung-Jen CJ; Lee, Su-Chen SC; Yen, Jeng-Hsien JH; Chang, Shun-Jen SJ
Publication Date: 2021-04-18

Variant appearance in text: rs4684847
PubMed Link: 33919522
Variant Present in the following documents:
  • Main text
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Association of Peroxisome Proliferator-Activated Receptors (PPARs) with Diabetic Retinopathy in Human and Animal Models: Analysis of the Literature and Genome Browsers.

Ppar Research
Tajnšek, Špela Š; Petrovič, Danijel D; Globočnik Petrovič, Mojca M; Kunej, Tanja T
Publication Date: 2020

Variant appearance in text: rs4684847
PubMed Link: 32190036
Variant Present in the following documents:
  • Main text
  • PPAR2020-1783564.pdf
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PRRX1-induced epithelial-to-mesenchymal transition in salivary adenoid cystic carcinoma activates the metabolic reprogramming of free fatty acids to promote invasion and metastasis.

Cell Proliferation
Jiang, Ya-Ping YP; Tang, Ya-Ling YL; Wang, Sha-Sha SS; Wu, Jia-Shun JS; Zhang, Mei M; Pang, Xin X; Wu, Jing-Biao JB; Chen, Yu Y; Tang, Ya-Jie YJ; Liang, Xin-Hua XH
Publication Date: 2020-01

Variant appearance in text: rs4684847
PubMed Link: 31657086
Variant Present in the following documents:
  • Main text
  • CPR-53-e12705.pdf
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Investigation of allele-specific expression of genes involved in adipogenesis and lipid metabolism suggests complex regulatory mechanisms of PPARGC1A expression in porcine fat tissues.

Bmc Genetics
Stachowiak, Monika M; Szczerbal, Izabela I; Flisikowski, Krzysztof K
Publication Date: 2018-11-29

Variant appearance in text: rs4684847
PubMed Link: 30497374
Variant Present in the following documents:
  • Main text
  • 12863_2018_Article_696.pdf
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Haplotype Analysis of PPARγ Gene Polymorphisms and the Lipoprotein (a) Level.

Iranian Journal Of Public Health
Shen, Chao C; Fan, Wei W; Xie, Hui-Jian HJ; Wu, Ming M; Zhou, Zheng-Yuan ZY; Guo, Zhi-Rong ZR; Dong, Chen C
Publication Date: 2018-07

Variant appearance in text: rs4684847
PubMed Link: 30181995
Variant Present in the following documents:
  • Main text
  • IJPH-47-973.pdf
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Computational analyses of obesity associated loci generated by genome-wide association studies.

Plos One
Cheng, Mengrong M; Mei, Bing B; Zhou, Qian Q; Zhang, Manling M; Huang, Han H; Han, Lanchun L; Huang, Qingyang Q
Publication Date: 2018

Variant appearance in text: rs4684847
PubMed Link: 29966015
Variant Present in the following documents:
  • Main text
  • pone.0199987.pdf
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Emerging applications of genome-editing technology to examine functionality of GWAS-associated variants for complex traits.

Physiological Genomics
Smith, Andrew J P AJP; Deloukas, Panos P; Munroe, Patricia B PB
Publication Date: 2018-07-01

Variant appearance in text: rs4684847
PubMed Link: 29652634
Variant Present in the following documents:
  • Main text
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Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.

Nature Genetics
Mahajan, Anubha A; Wessel, Jennifer J; Willems, Sara M SM; Zhao, Wei W; Robertson, Neil R NR; Chu, Audrey Y AY; Gan, Wei W; Kitajima, Hidetoshi H; Taliun, Daniel D; Rayner, N William NW; Guo, Xiuqing X; Lu, Yingchang Y; Li, Man M; Jensen, Richard A RA; Hu, Yao Y; Huo, Shaofeng S; Lohman, Kurt K KK; Zhang, Weihua W; Cook, James P JP; Prins, Bram Peter BP; Flannick, Jason J; Grarup, Niels N; Trubetskoy, Vassily Vladimirovich VV; Kravic, Jasmina J; Kim, Young Jin YJ; Rybin, Denis V DV; Yaghootkar, Hanieh H; Müller-Nurasyid, Martina M; Meidtner, Karina K; Li-Gao, Ruifang R; Varga, Tibor V TV; Marten, Jonathan J; Li, Jin J; Smith, Albert Vernon AV; An, Ping P; Ligthart, Symen S; Gustafsson, Stefan S; Malerba, Giovanni G; Demirkan, Ayse A; Tajes, Juan Fernandez JF; Steinthorsdottir, Valgerdur V; Wuttke, Matthias M; Lecoeur, Cécile C; Preuss, Michael M; Bielak, Lawrence F LF; Graff, Marielisa M; Highland, Heather M HM; Justice, Anne E AE; Liu, Dajiang J DJ; Marouli, Eirini E; Peloso, Gina Marie GM; Warren, Helen R HR; , ; , ; , ; Afaq, Saima S; Afzal, Shoaib S; Ahlqvist, Emma E; Almgren, Peter P; Amin, Najaf N; Bang, Lia B LB; Bertoni, Alain G AG; Bombieri, Cristina C; Bork-Jensen, Jette J; Brandslund, Ivan I; Brody, Jennifer A JA; Burtt, Noël P NP; Canouil, Mickaël M; Chen, Yii-Der Ida YI; Cho, Yoon Shin YS; Christensen, Cramer C; Eastwood, Sophie V SV; Eckardt, Kai-Uwe KU; Fischer, Krista K; Gambaro, Giovanni G; Giedraitis, Vilmantas V; Grove, Megan L ML; de Haan, Hugoline G HG; Hackinger, Sophie S; Hai, Yang Y; Han, Sohee S; Tybjærg-Hansen, Anne A; Hivert, Marie-France MF; Isomaa, Bo B; Jäger, Susanne S; Jørgensen, Marit E ME; Jørgensen, Torben T; Käräjämäki, Annemari A; Kim, Bong-Jo BJ; Kim, Sung Soo SS; Koistinen, Heikki A HA; Kovacs, Peter P; Kriebel, Jennifer J; Kronenberg, Florian F; Läll, Kristi K; Lange, Leslie A LA; Lee, Jung-Jin JJ; Lehne, Benjamin B; Li, Huaixing H; Lin, Keng-Hung KH; Linneberg, Allan A; Liu, Ching-Ti CT; Liu, Jun J; Loh, Marie M; Mägi, Reedik R; Mamakou, Vasiliki V; McKean-Cowdin, Roberta R; Nadkarni, Girish G; Neville, Matt M; Nielsen, Sune F SF; Ntalla, Ioanna I; Peyser, Patricia A PA; Rathmann, Wolfgang W; Rice, Kenneth K; Rich, Stephen S SS; Rode, Line L; Rolandsson, Olov O; Schönherr, Sebastian S; Selvin, Elizabeth E; Small, Kerrin S KS; Stančáková, Alena A; Surendran, Praveen P; Taylor, Kent D KD; Teslovich, Tanya M TM; Thorand, Barbara B; Thorleifsson, Gudmar G; Tin, Adrienne A; Tönjes, Anke A; Varbo, Anette A; Witte, Daniel R DR; Wood, Andrew R AR; Yajnik, Pranav P; Yao, Jie J; Yengo, Loïc L; Young, Robin R; Amouyel, Philippe P; Boeing, Heiner H; Boerwinkle, Eric E; Bottinger, Erwin P EP; Chowdhury, Rajiv R; Collins, Francis S FS; Dedoussis, George G; Dehghan, Abbas A; Deloukas, Panos P; Ferrario, Marco M MM; Ferrières, Jean J; Florez, Jose C JC; Frossard, Philippe P; Gudnason, Vilmundur V; Harris, Tamara B TB; Heckbert, Susan R SR; Howson, Joanna M M JMM; Ingelsson, Martin M; Kathiresan, Sekar S; Kee, Frank F; Kuusisto, Johanna J; Langenberg, Claudia C; Launer, Lenore J LJ; Lindgren, Cecilia M CM; Männistö, Satu S; Meitinger, Thomas T; Melander, Olle O; Mohlke, Karen L KL; Moitry, Marie M; Morris, Andrew D AD; Murray, Alison D AD; de Mutsert, Renée R; Orho-Melander, Marju M; Owen, Katharine R KR; Perola, Markus M; Peters, Annette A; Province, Michael A MA; Rasheed, Asif A; Ridker, Paul M PM; Rivadineira, Fernando F; Rosendaal, Frits R FR; Rosengren, Anders H AH; Salomaa, Veikko V; Sheu, Wayne H-H WH; Sladek, Rob R; Smith, Blair H BH; Strauch, Konstantin K; Uitterlinden, André G AG; Varma, Rohit R; Willer, Cristen J CJ; Blüher, Matthias M; Butterworth, Adam S AS; Chambers, John Campbell JC; Chasman, Daniel I DI; Danesh, John J; van Duijn, Cornelia C; Dupuis, Josée J; Franco, Oscar H OH; Franks, Paul W PW; Froguel, Philippe P; Grallert, Harald H; Groop, Leif L; Han, Bok-Ghee BG; Hansen, Torben T; Hattersley, Andrew T AT; Hayward, Caroline C; Ingelsson, Erik E; Kardia, Sharon L R SLR; Karpe, Fredrik F; Kooner, Jaspal Singh JS; Köttgen, Anna A; Kuulasmaa, Kari K; Laakso, Markku M; Lin, Xu X; Lind, Lars L; Liu, Yongmei Y; Loos, Ruth J F RJF; Marchini, Jonathan J; Metspalu, Andres A; Mook-Kanamori, Dennis D; Nordestgaard, Børge G BG; Palmer, Colin N A CNA; Pankow, James S JS; Pedersen, Oluf O; Psaty, Bruce M BM; Rauramaa, Rainer R; Sattar, Naveed N; Schulze, Matthias B MB; Soranzo, Nicole N; Spector, Timothy D TD; Stefansson, Kari K; Stumvoll, Michael M; Thorsteinsdottir, Unnur U; Tuomi, Tiinamaija T; Tuomilehto, Jaakko J; Wareham, Nicholas J NJ; Wilson, James G JG; Zeggini, Eleftheria E; Scott, Robert A RA; Barroso, Inês I; Frayling, Timothy M TM; Goodarzi, Mark O MO; Meigs, James B JB; Boehnke, Michael M; Saleheen, Danish D; Morris, Andrew P AP; Rotter, Jerome I JI; McCarthy, Mark I MI
Publication Date: 2018-04

Variant appearance in text: rs4684847
PubMed Link: 29632382
Variant Present in the following documents:
  • Main text
  • nihms938867.pdf
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Clinical relevance of peroxisome proliferator-activated receptor-γ gene polymorphisms with sepsis.

Journal Of Clinical Laboratory Analysis
Liu, Yu Y; Wan, Wenhui W; Fang, Fang F; Guo, Lei L; Zhao, Yusheng Y; Zhang, Xinghu X; Huang, Fang F
Publication Date: 2018-05

Variant appearance in text: rs4684847
PubMed Link: 29055064
Variant Present in the following documents:
  • Main text
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Allele-specific quantitative proteomics unravels molecular mechanisms modulated by cis-regulatory PPARG locus variation.

Nucleic Acids Research
Lee, Heekyoung H; Qian, Kun K; von Toerne, Christine C; Hoerburger, Lena L; Claussnitzer, Melina M; Hoffmann, Christoph C; Glunk, Viktoria V; Wahl, Simone S; Breier, Michaela M; Eck, Franziska F; Jafari, Leili L; Molnos, Sophie S; Grallert, Harald H; Dahlman, Ingrid I; Arner, Peter P; Brunner, Cornelia C; Hauner, Hans H; Hauck, Stefanie M SM; Laumen, Helmut H
Publication Date: 2017-04-07

Variant appearance in text: rs4684847
PubMed Link: 28334807
Variant Present in the following documents:
  • Main text
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Interaction between peroxisome proliferator-activated receptor gamma polymorphism and obesity on type 2 diabetes in a Chinese Han population.

Diabetology & Metabolic Syndrome
Lv, Xiaohui X; Zhang, Li L; Sun, Jiayu J; Cai, Zhigang Z; Gu, Qing Q; Zhang, Ruipeng R; Shan, Aiyun A
Publication Date: 2017

Variant appearance in text: rs4684847
PubMed Link: 28123453
Variant Present in the following documents:
  • Main text
  • 13098_2017_Article_205.pdf
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Monogenic Diabetes: What It Teaches Us on the Common Forms of Type 1 and Type 2 Diabetes.

Endocrine Reviews
Yang, Yisheng Y; Chan, Lawrence L
Publication Date: 2016-06

Variant appearance in text: rs4684847
PubMed Link: 27035557
Variant Present in the following documents:
  • Main text
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Computational Characterization of Osteoporosis Associated SNPs and Genes Identified by Genome-Wide Association Studies.

Plos One
Qin, Longjuan L; Liu, Yuyong Y; Wang, Ya Y; Wu, Guiju G; Chen, Jie J; Ye, Weiyuan W; Yang, Jiancai J; Huang, Qingyang Q
Publication Date: 2016

Variant appearance in text: rs4684847
PubMed Link: 26930606
Variant Present in the following documents:
  • Main text
  • pone.0150070.pdf
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Interaction between peroxisome proliferator- activated receptor gamma polymorphism and overweight on diabetic retinopathy in a Chinese case-control study.

International Journal Of Clinical And Experimental Medicine
Wang, Yan Y; Wang, Xin-Hua XH; Li, Ruo-Xi RX
Publication Date: 2015

Variant appearance in text: rs4684847
PubMed Link: 26885119
Variant Present in the following documents:
  • Main text
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Association of peroxisome proliferator-activated receptor-gamma gene polymorphisms and gene-gene interaction with asthma risk in a Chinese adults population.

International Journal Of Clinical And Experimental Medicine
Li, Wancheng W; Dai, Wenjing W; Sun, Jian J; Zhang, Wei W; Jiang, Yi Y; Ma, Chunlan C; Wang, Chunmao C; He, Jie J
Publication Date: 2015

Variant appearance in text: rs4684847
PubMed Link: 26770574
Variant Present in the following documents:
  • Main text
View BVdb publication page



Gene-Gene Interactions among Pparα/δ/γ Polymorphisms for Apolipoprotein (Apo) A-I/Apob Ratio in Chinese Han Population.

Iranian Journal Of Public Health
Hai, Bo B; Xie, Huijian H; Guo, Zhirong Z; Dong, Chen C; Wu, Ming M; Chen, Qiu Q; Zhou, Zhengyuan Z; Zhu, Qiurong Q; Liu, Mengmeng M; Fan, Wei W; Zhou, Hui H
Publication Date: 2014-06

Variant appearance in text: rs4684847
PubMed Link: 26110145
Variant Present in the following documents:
  • Main text
  • IJPH-43-749.pdf
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Association and interaction of PPARα, δ, and γ gene polymorphisms with low-density lipoprotein-cholesterol in a Chinese Han population.

Genetic Testing And Molecular Biomarkers
Fan, Wei W; Shen, Chao C; Wu, Ming M; Zhou, Zheng-Yuan ZY; Guo, Zhi-Rong ZR
Publication Date: 2015-07

Variant appearance in text: rs4684847
PubMed Link: 26098621
Variant Present in the following documents:
  • Main text
View BVdb publication page



Role of peroxisome proliferator-activated receptors gene polymorphisms in type 2 diabetes and metabolic syndrome.

World Journal Of Diabetes
Dong, Chen C; Zhou, Hui H; Shen, Chong C; Yu, Lu-Gang LG; Ding, Yi Y; Zhang, Yong-Hong YH; Guo, Zhi-Rong ZR
Publication Date: 2015-05-15

Variant appearance in text: rs4684847
PubMed Link: 25987964
Variant Present in the following documents:
  • Main text
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Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms.

Cell
Claussnitzer, Melina M; Dankel, Simon N SN; Klocke, Bernward B; Grallert, Harald H; Glunk, Viktoria V; Berulava, Tea T; Lee, Heekyoung H; Oskolkov, Nikolay N; Fadista, Joao J; Ehlers, Kerstin K; Wahl, Simone S; Hoffmann, Christoph C; Qian, Kun K; Rönn, Tina T; Riess, Helene H; Müller-Nurasyid, Martina M; Bretschneider, Nancy N; Schroeder, Timm T; Skurk, Thomas T; Horsthemke, Bernhard B; , ; Spieler, Derek D; Klingenspor, Martin M; Seifert, Martin M; Kern, Michael J MJ; Mejhert, Niklas N; Dahlman, Ingrid I; Hansson, Ola O; Hauck, Stefanie M SM; Blüher, Matthias M; Arner, Peter P; Groop, Leif L; Illig, Thomas T; Suhre, Karsten K; Hsu, Yi-Hsiang YH; Mellgren, Gunnar G; Hauner, Hans H; Laumen, Helmut H
Publication Date: 2014-01-16

Variant appearance in text: rs4684847
PubMed Link: 24439387
Variant Present in the following documents:
  • Main text
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Association of peroxisome proliferator-activated receptor α/δ/γ with obesity, and gene-gene interaction, in the Chinese Han population.

Journal Of Epidemiology
Luo, Wenshu W; Guo, Zhirong Z; Wu, Ming M; Hao, Chao C; Hu, Xiaoshu X; Zhou, Zhengyuan Z; Zhou, Zhiwu Z; Yao, Xingjuan X; Zhang, Lijun L; Liu, Jingchao J
Publication Date: 2013

Variant appearance in text: rs4684847
PubMed Link: 23545576
Variant Present in the following documents:
  • Main text
  • je-23-187.pdf
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Relationships between selected gene polymorphisms and blood pressure sensitivity to weight loss in elderly persons with hypertension.

Hypertension (Dallas, Tex. : 1979)
Kostis, William J WJ; Cabrera, Javier J; Hooper, W Craig WC; Whelton, Paul K PK; Espeland, Mark A MA; Cosgrove, Nora M NM; Cheng, Jerry Q JQ; Deng, Yingzi Y; De Staerck, Christine C; Pyle, Meredith M; Maruthur, Nisa N; Reyes, Ingrid I; Anderson, Cheryl A M CA; Liu, Jie J; Kostis, John B JB
Publication Date: 2013-04

Variant appearance in text: rs4684847
PubMed Link: 23438931
Variant Present in the following documents:
  • Main text
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Single nucleotide polymorphisms in obesity-related genes and all-cause and cause-specific mortality: a prospective cohort study.

Bmc Medical Genetics
Gallicchio, Lisa L; Chang, Howard H HH; Christo, Dana K DK; Thuita, Lucy L; Huang, Han Yao HY; Strickland, Paul P; Ruczinski, Ingo I; Clipp, Sandra S; Helzlsouer, Kathy J KJ
Publication Date: 2009-10-09

Variant appearance in text: rs4684847
PubMed Link: 19818126
Variant Present in the following documents:
  • Main text
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Genetic polymorphisms of peroxisome proliferator-activated receptors and the risk of cardiovascular morbidity and mortality in a community-based cohort in washington county, Maryland.

Ppar Research
Gallicchio, L L; Kalesan, Bindu B; Huang, Han-Yao HY; Strickland, Paul P; Hoffman, Sandra C SC; Helzlsouer, Kathy J KJ
Publication Date: 2008

Variant appearance in text: rs4684847
PubMed Link: 18288282
Variant Present in the following documents:
  • Main text
  • PPAR2008-276581.pdf
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