Publications:

Importance of the Proximity and Orientation of Ligand-Linkage to the Design of Cinnamate-GW9662 Hybrid Compounds as Covalent PPARγ Agonists.

Molecules (Basel, Switzerland)

Utsugi, Yuki Y; Kobuchi, Hirona H; Kawamura, Yukio Y; Atito, Ahmed Salahelden Aboelhamd ASA; Nagao, Masaya M; Isoda, Hiroko H; Miyamae, Yusaku Y

Publication Date: 2019-05-27

Variant appearance in text: PPARgamma: Cys285Ala

PubMed Link: 31137814

Variant Present in the following documents:

• molecules-24-02019.pdf

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A compound-based proteomic approach discloses 15-ketoatractyligenin methyl ester as a new PPARγ partial agonist with anti-proliferative ability.

Scientific Reports

Vasaturo, Michele M; Fiengo, Lorenzo L; De Tommasi, Nunziatina N; Sabatino, Lina L; Ziccardi, Pamela P; Colantuoni, Vittorio V; Bruno, Maurizio M; Cerchia, Carmen C; Novellino, Ettore E; Lupo, Angelo A; Lavecchia, Antonio A; Piaz, Fabrizio Dal FD

Publication Date: 2017-01-24

Variant appearance in text: PPARgamma: C285A

PubMed Link: 28117438

Variant Present in the following documents:

• srep41273.pdf

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Structural basis for PPARγ transactivation by endocrine-disrupting organotin compounds.

Scientific Reports

Harada, Shusaku S; Hiromori, Youhei Y; Nakamura, Shota S; Kawahara, Kazuki K; Fukakusa, Shunsuke S; Maruno, Takahiro T; Noda, Masanori M; Uchiyama, Susumu S; Fukui, Kiichi K; Nishikawa, Jun-ichi J; Nagase, Hisamitsu H; Kobayashi, Yuji Y; Yoshida, Takuya T; Ohkubo, Tadayasu T; Nakanishi, Tsuyoshi T

Publication Date: 2015-02-17

Variant appearance in text: PPARgamma: C285A

PubMed Link: 25687586

Variant Present in the following documents:

• srep08520.pdf

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An alternate binding site for PPARγ ligands.

Nature Communications

Hughes, Travis S TS; Giri, Pankaj Kumar PK; de Vera, Ian Mitchelle S IM; Marciano, David P DP; Kuruvilla, Dana S DS; Shin, Youseung Y; Blayo, Anne-Laure AL; Kamenecka, Theodore M TM; Burris, Thomas P TP; Griffin, Patrick R PR; Kojetin, Douglas J DJ

Publication Date: 2014-04-07

Variant appearance in text: PPARgamma: Cys285Ala

PubMed Link: 24705063

Variant Present in the following documents:

• nihms573621.pdf

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Covalent peroxisome proliferator-activated receptor gamma adduction by nitro-fatty acids: selective ligand activity and anti-diabetic signaling actions.

The Journal Of Biological Chemistry

Schopfer, Francisco J FJ; Cole, Marsha P MP; Groeger, Alison L AL; Chen, Chen-Shan CS; Khoo, Nicholas K H NK; Woodcock, Steven R SR; Golin-Bisello, Franca F; Motanya, U Nkiru UN; Li, Yong Y; Zhang, Jifeng J; Garcia-Barrio, Minerva T MT; Rudolph, Tanja K TK; Rudolph, Volker V; Bonacci, Gustavo G; Baker, Paul R S PR; Xu, H Eric HE; Batthyany, Carlos I CI; Chen, Y Eugene YE; Hallis, Tina M TM; Freeman, Bruce A BA

Publication Date: 2010-04-16

Variant appearance in text: PPARgamma: C285A

PubMed Link: 20097754

Variant Present in the following documents:

• Main text

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