Application of Prostate Cancer Models for Preclinical Study: Advantages and Limitations of Cell Lines, Patient-Derived Xenografts, and Three-Dimensional Culture of Patient-Derived Cells.
Androgen receptor-dependent and -independent mechanisms driving prostate cancer progression: Opportunities for therapeutic targeting from multiple angles.
Oncotarget
Hoang, David T DT; Iczkowski, Kenneth A KA; Kilari, Deepak D; See, William W; Nevalainen, Marja T MT
Proteomic Upregulation of Fatty Acid Synthase and Fatty Acid Binding Protein 5 and Identification of Cancer- and Race-Specific Pathway Associations in Human Prostate Cancer Tissues.
Journal Of Cancer
Myers, Jennifer S JS; von Lersner, Ariana K AK; Sang, Qing-Xiang Amy QX
miR-137 Targets p160 Steroid Receptor Coactivators SRC1, SRC2, and SRC3 and Inhibits Cell Proliferation.
Molecular Endocrinology (Baltimore, Md.)
Eedunuri, Vijay Kumar VK; Rajapakshe, Kimal K; Fiskus, Warren W; Geng, Chuandong C; Chew, Sue Anne SA; Foley, Christopher C; Shah, Shrijal S SS; Shou, John J; Mohamed, Junaith S JS; Coarfa, Cristian C; O'Malley, Bert W BW; Mitsiades, Nicholas N
Expression and functional role of orphan receptor GPR158 in prostate cancer growth and progression.
Plos One
Patel, Nitin N; Itakura, Tatsuo T; Jeong, Shinwu S; Liao, Chun-Peng CP; Roy-Burman, Pradip P; Zandi, Ebrahim E; Groshen, Susan S; Pinski, Jacek J; Coetzee, Gerhard A GA; Gross, Mitchell E ME; Fini, M Elizabeth ME
Androgen suppresses the proliferation of androgen receptor-positive castration-resistant prostate cancer cells via inhibition of Cdk2, CyclinA, and Skp2.
Plos One
Kokontis, John M JM; Lin, Hui-Ping HP; Jiang, Shih Sheng SS; Lin, Ching-Yu CY; Fukuchi, Junichi J; Hiipakka, Richard A RA; Chung, Chi-Jung CJ; Chan, Tzu-Min TM; Liao, Shutsung S; Chang, Chung-Ho CH; Chuu, Chih-Pin CP
Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells.
Proceedings Of The National Academy Of Sciences Of The United States Of America
De Leon, Johanny Tonos JT; Iwai, Aki A; Feau, Clementine C; Garcia, Yenni Y; Balsiger, Heather A HA; Storer, Cheryl L CL; Suro, Raquel M RM; Garza, Kristine M KM; Lee, Sunmin S; Kim, Yeong Sang YS; Chen, Yu Y; Ning, Yang-Min YM; Riggs, Daniel L DL; Fletterick, Robert J RJ; Guy, R Kiplin RK; Trepel, Jane B JB; Neckers, Leonard M LM; Cox, Marc B MB
Leupaxin, a novel coactivator of the androgen receptor, is expressed in prostate cancer and plays a role in adhesion and invasion of prostate carcinoma cells.
Molecular Endocrinology (Baltimore, Md.)
Kaulfuss, Silke S; Grzmil, Michal M; Hemmerlein, Bernhard B; Thelen, Paul P; Schweyer, Stefan S; Neesen, Jürgen J; Bubendorf, Lukas L; Glass, Andrew G AG; Jarry, Hubertus H; Auber, Bernd B; Burfeind, Peter P
The androgen receptor can signal through Wnt/beta-Catenin in prostate cancer cells as an adaptation mechanism to castration levels of androgens.
Bmc Cell Biology
Schweizer, Liang L; Rizzo, Cheryl A CA; Spires, Thomas E TE; Platero, J Suso JS; Wu, Qiuyan Q; Lin, Tai-An TA; Gottardis, Marco M MM; Attar, Ricardo M RM
Discovery of antiandrogen activity of nonsteroidal scaffolds of marketed drugs.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Bisson, W H WH; Cheltsov, A V AV; Bruey-Sedano, N N; Lin, B B; Chen, J J; Goldberger, N N; May, L T LT; Christopoulos, A A; Dalton, J T JT; Sexton, P M PM; Zhang, X-K XK; Abagyan, R R