SI c.1580A>T ;(p.Y527F)

Variant ID: 3-164767596-T-A

NM_001041.3(SI):c.1580A>T;(p.Y527F)

This variant was identified in 13 publications

View GRCh38 version.




Publications:


An Ethanol Extract of Perilla frutescens Leaves Suppresses Adrenergic Agonist-Induced Metastatic Ability of Cancer Cells by Inhibiting Src-Mediated EMT.

Molecules (Basel, Switzerland)
Jeong, Jae-Hoon JH; Park, Hyun-Ji HJ; Chi, Gyoo-Yong GY; Choi, Yung-Hyun YH; Park, Shin-Hyung SH
Publication Date: 2023-04-12

Variant appearance in text: SI: Y527F
PubMed Link: 37110648
Variant Present in the following documents:
  • molecules-28-03414.pdf
View BVdb publication page



Src family kinases inhibit differentiation of intestinal epithelial cells through the Hippo effector YAP1.

Biology Open
Fallah, Sepideh S; Beaulieu, Jean-François JF
Publication Date: 2021-11-15

Variant appearance in text: SI: Y527F
PubMed Link: 34693980
Variant Present in the following documents:
  • Main text
  • biolopen-10-058904.pdf
View BVdb publication page



Time-Variant SRC Kinase Activation Determines Endothelial Permeability Response.

Cell Chemical Biology
Klomp, Jennifer E JE; Shaaya, Mark M; Matsche, Jacob J; Rebiai, Rima R; Aaron, Jesse S JS; Collins, Kerrie B KB; Huyot, Vincent V; Gonzalez, Annette M AM; Muller, William A WA; Chew, Teng-Leong TL; Malik, Asrar B AB; Karginov, Andrei V AV
Publication Date: 2019-08-15

Variant appearance in text: SI: Y527F
PubMed Link: 31130521
Variant Present in the following documents:
  • Main text
View BVdb publication page



Syntenin mediates SRC function in exosomal cell-to-cell communication.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Imjeti, Naga Sailaja NS; Menck, Kerstin K; Egea-Jimenez, Antonio Luis AL; Lecointre, Celine C; Lembo, Frederique F; Bouguenina, Habib H; Badache, Ali A; Ghossoub, Rania R; David, Guido G; Roche, Serge S; Zimmermann, Pascale P
Publication Date: 2017-11-21

Variant appearance in text: SI: Y527F
PubMed Link: 29109268
Variant Present in the following documents:
  • Main text
  • pnas.201713433.pdf
  • pnas.201713433SI.pdf
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Ameloblastin induces tumor suppressive phenotype and enhances chemosensitivity to doxorubicin via Src-Stat3 inactivation in osteosarcoma.

Scientific Reports
Ando, Toshinori T; Kudo, Yasusei Y; Iizuka, Shinji S; Tsunematsu, Takaaki T; Umehara, Hanako H; Shrestha, Madhu M; Matsuo, Toshihiro T; Kubo, Tadahiko T; Shimose, Shouji S; Arihiro, Koji K; Ogawa, Ikuko I; Ochi, Mitsuo M; Takata, Takashi T
Publication Date: 2017-01-05

Variant appearance in text: SI: Y527F
PubMed Link: 28054649
Variant Present in the following documents:
  • srep40187.pdf
View BVdb publication page



Activation of oncogenic tyrosine kinase signaling promotes insulin receptor-mediated cone photoreceptor survival.

Oncotarget
Rajala, Ammaji A; Wang, Yuhong Y; Rajala, Raju V S RV
Publication Date: 2016-07-26

Variant appearance in text: SI: Y527F
PubMed Link: 27391439
Variant Present in the following documents:
  • oncotarget-07-46924.pdf
View BVdb publication page



Identification of biallelic LRRK1 mutations in osteosclerotic metaphyseal dysplasia and evidence for locus heterogeneity.

Journal Of Medical Genetics
Iida, Aritoshi A; Xing, Weirong W; Docx, Martine K F MK; Nakashima, Tomoki T; Wang, Zheng Z; Kimizuka, Mamori M; Van Hul, Wim W; Rating, Dietz D; Spranger, Jürgen J; Ohashi, Hirohumi H; Miyake, Noriko N; Matsumoto, Naomichi N; Mohan, Subburaman S; Nishimura, Gen G; Mortier, Geert G; Ikegawa, Shiro S
Publication Date: 2016-08

Variant appearance in text: SI: Y527F
PubMed Link: 27055475
Variant Present in the following documents:
  • Main text
View BVdb publication page



Src Inhibition Blocks c-Myc Translation and Glucose Metabolism to Prevent the Development of Breast Cancer.

Cancer Research
Jain, Shalini S; Wang, Xiao X; Chang, Chia-Chi CC; Ibarra-Drendall, Catherine C; Wang, Hai H; Zhang, Qingling Q; Brady, Samuel W SW; Li, Ping P; Zhao, Hong H; Dobbs, Jessica J; Kyrish, Matt M; Tkaczyk, Tomasz S TS; Ambrose, Adrian A; Sistrunk, Christopher C; Arun, Banu K BK; Richards-Kortum, Rebecca R; Jia, Wei W; Seewaldt, Victoria L VL; Yu, Dihua D
Publication Date: 2015-11-15

Variant appearance in text: SI: Y527F
PubMed Link: 26383165
Variant Present in the following documents:
  • Main text
View BVdb publication page



Digoxin Suppresses Tumor Malignancy through Inhibiting Multiple Src-Related Signaling Pathways in Non-Small Cell Lung Cancer.

Plos One
Lin, Sheng-Yi SY; Chang, Hsiu-Hui HH; Lai, Yi-Hua YH; Lin, Ching-Hsiung CH; Chen, Min-Hsuan MH; Chang, Gee-Chen GC; Tsai, Meng-Feng MF; Chen, Jeremy J W JJ
Publication Date: 2015

Variant appearance in text: SI: Y527F
PubMed Link: 25955608
Variant Present in the following documents:
  • pone.0123305.pdf
View BVdb publication page



Src-dependent Tks5 phosphorylation regulates invadopodia-associated invasion in prostate cancer cells.

The Prostate
Burger, Karen L KL; Learman, Brian S BS; Boucherle, Amy K AK; Sirintrapun, S Joseph SJ; Isom, Scott S; Díaz, Begoña B; Courtneidge, Sara A SA; Seals, Darren F DF
Publication Date: 2014-02

Variant appearance in text: SI: Y527F
PubMed Link: 24174371
Variant Present in the following documents:
  • Main text
View BVdb publication page



Tyrosine 416 is phosphorylated in the closed, repressed conformation of c-Src.

Plos One
Irtegun, Sevgi S; Wood, Rebecca J RJ; Ormsby, Angelique R AR; Mulhern, Terrence D TD; Hatters, Danny M DM
Publication Date: 2013

Variant appearance in text: SI: Y527F
PubMed Link: 23923048
Variant Present in the following documents:
  • Main text
  • pone.0071035.pdf
View BVdb publication page



The endosomal adaptor protein APPL1 impairs the turnover of leading edge adhesions to regulate cell migration.

Molecular Biology Of The Cell
Broussard, Joshua A JA; Lin, Wan-hsin WH; Majumdar, Devi D; Anderson, Bridget B; Eason, Brady B; Brown, Claire M CM; Webb, Donna J DJ
Publication Date: 2012-04

Variant appearance in text: SI: Y527F
PubMed Link: 22379109
Variant Present in the following documents:
  • 1486.pdf
View BVdb publication page



VEGF modulates NMDA receptors activity in cerebellar granule cells through Src-family kinases before synapse formation.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Meissirel, Claire C; Ruiz de Almodovar, Carmen C; Knevels, Ellen E; Coulon, Cathy C; Chounlamountri, Naura N; Segura, Inmaculada I; de Rossi, Pierre P; Vinckier, Stefan S; Anthonis, Kristof K; Deléglise, Bérangère B; de Mol, Maria M; Ali, Carine C; Dassonville, Karel K; Loyens, Ellen E; Honnorat, Jérôme J; Michotte, Yvette Y; Rogemond, Véronique V; Smolders, Ilse I; Voets, Thomas T; Vivien, Denis D; Vanden Berghe, Pieter P; Van den Bosch, Ludo L; Robberecht, Wim W; Chédotal, Alain A; Oliviero, Salvatore S; Dewerchin, Mieke M; Schmucker, Dietmar D; Thomasset, Nicole N; Salin, Paul P; Carmeliet, Peter P
Publication Date: 2011-08-16

Variant appearance in text: SI: Y527F
PubMed Link: 21804034
Variant Present in the following documents:
  • Main text
View BVdb publication page