SI c.643_644delinsTA ;(p.T215Y)

Variant ID: 3-164783212-GT-TA

NM_001041.3(SI):c.643_644delinsTA;(p.T215Y)

This variant was identified in 19 publications

View GRCh38 version.




Publications:


Possible involvement of distinct phylogenetic clusters of HIV-1 variants in the discrepancies between coreceptor tropism predictions based on viral RNA and proviral DNA.

Journal Of Pharmaceutical Health Care And Sciences
Kotani, Hiroshi H; Sudo, Koji K; Hasegawa, Naoki N; Fujiwara, Hiroshi H; Hayakawa, Tomohisa T; Iketani, Osamu O; Yamaguchi, Masaya M; Mochizuki, Mayumi M; Iwata, Satoshi S; Kato, Shingo S
Publication Date: 2016

Variant appearance in text: SI: T215Y
PubMed Link: 27833760
Variant Present in the following documents:
  • Main text
  • 40780_2016_Article_65.pdf
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Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis-Binding of Foscarnet.

Acs Chemical Biology
Das, Kalyan K; Balzarini, Jan J; Miller, Matthew T MT; Maguire, Anita R AR; DeStefano, Jeffrey J JJ; Arnold, Eddy E
Publication Date: 2016-08-19

Variant appearance in text: SI: T215Y
PubMed Link: 27192549
Variant Present in the following documents:
  • Main text
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Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Brai, Annalaura A; Fazi, Roberta R; Tintori, Cristina C; Zamperini, Claudio C; Bugli, Francesca F; Sanguinetti, Maurizio M; Stigliano, Egidio E; Esté, José J; Badia, Roger R; Franco, Sandra S; Martinez, Miguel A MA; Martinez, Javier P JP; Meyerhans, Andreas A; Saladini, Francesco F; Zazzi, Maurizio M; Garbelli, Anna A; Maga, Giovanni G; Botta, Maurizio M
Publication Date: 2016-05-10

Variant appearance in text: SI: T215Y
PubMed Link: 27118832
Variant Present in the following documents:
  • Main text
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Optimization of the antiviral potency and lipophilicity of halogenated 2,6-diarylpyridinamines as a novel class of HIV-1 NNRTIS.

Chemmedchem
Wu, Zhi-Yuan ZY; Liu, Na N; Qin, Bingjie B; Huang, Li L; Yu, Fei F; Qian, Keduo K; Morris-Natschke, Susan L SL; Jiang, Shibo S; Chen, Chin Ho CH; Lee, Kuo-Hsiung KH; Xie, Lan L
Publication Date: 2014-07

Variant appearance in text: SI: T215Y
PubMed Link: 24895029
Variant Present in the following documents:
  • Main text
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Molecular dynamics study of HIV-1 RT-DNA-nevirapine complexes explains NNRTI inhibition and resistance by connection mutations.

Proteins
Vijayan, R S K RS; Arnold, Eddy E; Das, Kalyan K
Publication Date: 2014-05

Variant appearance in text: SI: T215Y
PubMed Link: 24174331
Variant Present in the following documents:
  • Main text
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HIV-1 drug-resistance surveillance among treatment-experienced and -naïve patients after the implementation of antiretroviral therapy in Ghana.

Plos One
Nii-Trebi, Nicholas I NI; Ibe, Shiro S; Barnor, Jacob S JS; Ishikawa, Koichi K; Brandful, James A M JA; Ofori, Sampson B SB; Yamaoka, Shoji S; Ampofo, William K WK; Sugiura, Wataru W
Publication Date: 2013

Variant appearance in text: SI: T215Y
PubMed Link: 23977189
Variant Present in the following documents:
  • Main text
  • pone.0071972.pdf
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Design, synthesis, and preclinical evaluations of novel 4-substituted 1,5-diarylanilines as potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) drug candidates.

Journal Of Medicinal Chemistry
Sun, Lian-Qi LQ; Zhu, Lei L; Qian, Keduo K; Qin, Bingjie B; Huang, Li L; Chen, Chin Ho CH; Lee, Kuo-Hsiung KH; Xie, Lan L
Publication Date: 2012-08-23

Variant appearance in text: SI: T215Y
PubMed Link: 22856541
Variant Present in the following documents:
  • Main text
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Factors limiting the transmission of HIV mutations conferring drug resistance: fitness costs and genetic bottlenecks.

Scientific Reports
Wagner, Bradley G BG; Garcia-Lerma, J Gerardo JG; Blower, Sally S
Publication Date: 2012

Variant appearance in text: SI: T215Y
PubMed Link: 22432052
Variant Present in the following documents:
  • Main text
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Randomized trial of time-limited interruptions of protease inhibitor-based antiretroviral therapy (ART) vs. continuous therapy for HIV-1 infection.

Plos One
Firnhaber, Cynthia C; Azzoni, Livio L; Foulkes, Andrea S AS; Gross, Robert R; Yin, Xiangfan X; Van Amsterdam, Desiree D; Schulze, Doreen D; Glencross, Deborah K DK; Stevens, Wendy W; Hunt, Gillian G; Morris, Lynn L; Fox, Lawrence L; Sanne, Ian I; Montaner, Luis J LJ
Publication Date: 2011

Variant appearance in text: SI: T215Y
PubMed Link: 21738668
Variant Present in the following documents:
  • pone.0021450.s002.pdf
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Design, synthesis, and evaluation of diarylpyridines and diarylanilines as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.

Journal Of Medicinal Chemistry
Tian, Xingtao X; Qin, Bingjie B; Wu, Zhiyuan Z; Wang, Xiaofeng X; Lu, Hong H; Morris-Natschke, Susan L SL; Chen, Chin Ho CH; Jiang, Shibo S; Lee, Kuo-Hsiung KH; Xie, Lan L
Publication Date: 2010-12-09

Variant appearance in text: SI: T215Y
PubMed Link: 21049929
Variant Present in the following documents:
  • Main text
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Diarylaniline derivatives as a distinct class of HIV-1 non-nucleoside reverse transcriptase inhibitors.

Journal Of Medicinal Chemistry
Qin, Bingjie B; Jiang, Xingkai X; Lu, Hong H; Tian, Xingtao X; Barbault, Florent F; Huang, Li L; Qian, Keduo K; Chen, Chin-Ho CH; Huang, Rong R; Jiang, Shibo S; Lee, Kuo-Hsiung KH; Xie, Lan L
Publication Date: 2010-07-08

Variant appearance in text: SI: T215Y
PubMed Link: 20527972
Variant Present in the following documents:
  • Main text
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Inhibition of human immunodeficiency virus type 1 by triciribine involves the accessory protein nef.

Antimicrobial Agents And Chemotherapy
Ptak, Roger G RG; Gentry, Brian G BG; Hartman, Tracy L TL; Watson, Karen M KM; Osterling, M Clayton MC; Buckheit, Robert W RW; Townsend, Leroy B LB; Drach, John C JC
Publication Date: 2010-04

Variant appearance in text: SI: T215Y
PubMed Link: 20086149
Variant Present in the following documents:
  • Main text
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Detecting and understanding combinatorial mutation patterns responsible for HIV drug resistance.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Zhang, Jing J; Hou, Tingjun T; Wang, Wei W; Liu, Jun S JS
Publication Date: 2010-01-26

Variant appearance in text: SI: T215Y
PubMed Link: 20080674
Variant Present in the following documents:
  • Main text
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Replication and drug resistant mutation of HIV-1 subtype B' (Thailand B) variants isolated from HAART treatment individuals in China.

Virology Journal
Sun, Jianping J; Ma, Liying L; Yu, Xiaoling X; Huang, Yang Y; Yuan, Lin L; Shao, Yiming Y
Publication Date: 2009-11-18

Variant appearance in text: SI: T215Y
PubMed Link: 19922621
Variant Present in the following documents:
  • Main text
  • 1743-422X-6-201.pdf
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Envelope coreceptor tropism, drug resistance, and viral evolution among subtype C HIV-1-infected individuals receiving nonsuppressive antiretroviral therapy.

Journal Of Acquired Immune Deficiency Syndromes (1999)
Kassaye, Seble S; Johnston, Elizabeth E; McColgan, Bryan B; Kantor, Rami R; Zijenah, Lynn L; Katzenstein, David D
Publication Date: 2009-01-01

Variant appearance in text: SI: T215Y
PubMed Link: 19295330
Variant Present in the following documents:
  • Main text
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Preclinical evaluation of GS-9160, a novel inhibitor of human immunodeficiency virus type 1 integrase.

Antimicrobial Agents And Chemotherapy
Jones, Gregg S GS; Yu, Fang F; Zeynalzadegan, Ameneh A; Hesselgesser, Joseph J; Chen, Xiaowu X; Chen, James J; Jin, Haolun H; Kim, Choung U CU; Wright, Matthew M; Geleziunas, Romas R; Tsiang, Manuel M
Publication Date: 2009-03

Variant appearance in text: SI: T215Y
PubMed Link: 19104010
Variant Present in the following documents:
  • Main text
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Mutations in the connection domain of HIV-1 reverse transcriptase increase 3'-azido-3'-deoxythymidine resistance.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Nikolenko, Galina N GN; Delviks-Frankenberry, Krista A KA; Palmer, Sarah S; Maldarelli, Frank F; Fivash, Matthew J MJ; Coffin, John M JM; Pathak, Vinay K VK
Publication Date: 2007-01-02

Variant appearance in text: SI: T215Y
PubMed Link: 17179211
Variant Present in the following documents:
  • Main text
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Randomized, controlled trial of therapy interruption in chronic HIV-1 infection.

Plos Medicine
Papasavvas, Emmanouil E; Kostman, Jay R JR; Mounzer, Karam K; Grant, Robert M RM; Gross, Robert R; Gallo, Cele C; Azzoni, Livio L; Foulkes, Andrea A; Thiel, Brian B; Pistilli, Maxwell M; Mackiewicz, Agnieszka A; Shull, Jane J; Montaner, Luis J LJ
Publication Date: 2004-12

Variant appearance in text: SI: T215Y
PubMed Link: 15630469
Variant Present in the following documents:
  • pmed.0010064.pdf
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