Possible involvement of distinct phylogenetic clusters of HIV-1 variants in the discrepancies between coreceptor tropism predictions based on viral RNA and proviral DNA.
Journal Of Pharmaceutical Health Care And Sciences
Kotani, Hiroshi H; Sudo, Koji K; Hasegawa, Naoki N; Fujiwara, Hiroshi H; Hayakawa, Tomohisa T; Iketani, Osamu O; Yamaguchi, Masaya M; Mochizuki, Mayumi M; Iwata, Satoshi S; Kato, Shingo S
Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Brai, Annalaura A; Fazi, Roberta R; Tintori, Cristina C; Zamperini, Claudio C; Bugli, Francesca F; Sanguinetti, Maurizio M; Stigliano, Egidio E; Esté, José J; Badia, Roger R; Franco, Sandra S; Martinez, Miguel A MA; Martinez, Javier P JP; Meyerhans, Andreas A; Saladini, Francesco F; Zazzi, Maurizio M; Garbelli, Anna A; Maga, Giovanni G; Botta, Maurizio M
Optimization of the antiviral potency and lipophilicity of halogenated 2,6-diarylpyridinamines as a novel class of HIV-1 NNRTIS.
Chemmedchem
Wu, Zhi-Yuan ZY; Liu, Na N; Qin, Bingjie B; Huang, Li L; Yu, Fei F; Qian, Keduo K; Morris-Natschke, Susan L SL; Jiang, Shibo S; Chen, Chin Ho CH; Lee, Kuo-Hsiung KH; Xie, Lan L
HIV-1 drug-resistance surveillance among treatment-experienced and -naïve patients after the implementation of antiretroviral therapy in Ghana.
Plos One
Nii-Trebi, Nicholas I NI; Ibe, Shiro S; Barnor, Jacob S JS; Ishikawa, Koichi K; Brandful, James A M JA; Ofori, Sampson B SB; Yamaoka, Shoji S; Ampofo, William K WK; Sugiura, Wataru W
Design, synthesis, and preclinical evaluations of novel 4-substituted 1,5-diarylanilines as potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) drug candidates.
Journal Of Medicinal Chemistry
Sun, Lian-Qi LQ; Zhu, Lei L; Qian, Keduo K; Qin, Bingjie B; Huang, Li L; Chen, Chin Ho CH; Lee, Kuo-Hsiung KH; Xie, Lan L
Inhibition of human immunodeficiency virus type 1 by triciribine involves the accessory protein nef.
Antimicrobial Agents And Chemotherapy
Ptak, Roger G RG; Gentry, Brian G BG; Hartman, Tracy L TL; Watson, Karen M KM; Osterling, M Clayton MC; Buckheit, Robert W RW; Townsend, Leroy B LB; Drach, John C JC
Envelope coreceptor tropism, drug resistance, and viral evolution among subtype C HIV-1-infected individuals receiving nonsuppressive antiretroviral therapy.
Journal Of Acquired Immune Deficiency Syndromes (1999)
Kassaye, Seble S; Johnston, Elizabeth E; McColgan, Bryan B; Kantor, Rami R; Zijenah, Lynn L; Katzenstein, David D
Preclinical evaluation of GS-9160, a novel inhibitor of human immunodeficiency virus type 1 integrase.
Antimicrobial Agents And Chemotherapy
Jones, Gregg S GS; Yu, Fang F; Zeynalzadegan, Ameneh A; Hesselgesser, Joseph J; Chen, Xiaowu X; Chen, James J; Jin, Haolun H; Kim, Choung U CU; Wright, Matthew M; Geleziunas, Romas R; Tsiang, Manuel M
Mutations in the connection domain of HIV-1 reverse transcriptase increase 3'-azido-3'-deoxythymidine resistance.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Nikolenko, Galina N GN; Delviks-Frankenberry, Krista A KA; Palmer, Sarah S; Maldarelli, Frank F; Fivash, Matthew J MJ; Coffin, John M JM; Pathak, Vinay K VK
Randomized, controlled trial of therapy interruption in chronic HIV-1 infection.
Plos Medicine
Papasavvas, Emmanouil E; Kostman, Jay R JR; Mounzer, Karam K; Grant, Robert M RM; Gross, Robert R; Gallo, Cele C; Azzoni, Livio L; Foulkes, Andrea A; Thiel, Brian B; Pistilli, Maxwell M; Mackiewicz, Agnieszka A; Shull, Jane J; Montaner, Luis J LJ